LUC00159I2 - - Google Patents

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Publication number
LUC00159I2
LUC00159I2 LU00159C LUC00159C LUC00159I2 LU C00159 I2 LUC00159 I2 LU C00159I2 LU 00159 C LU00159 C LU 00159C LU C00159 C LUC00159 C LU C00159C LU C00159 I2 LUC00159 I2 LU C00159I2
Authority
LU
Luxembourg
Application number
LU00159C
Original Assignee
Recordati Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43735742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00159(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Ag filed Critical Recordati Ag
Publication of LUC00159I1 publication Critical patent/LUC00159I1/fr
Publication of LUC00159I2 publication Critical patent/LUC00159I2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/6506Five-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU00159C 2010-01-14 2020-06-16 LUC00159I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29498010P 2010-01-14 2010-01-14
PCT/US2011/021100 WO2011088188A1 (fr) 2010-01-14 2011-01-13 Utilisation d'un agent de modification d'hormones surrénaliennes

Publications (2)

Publication Number Publication Date
LUC00159I1 LUC00159I1 (fr) 2020-06-16
LUC00159I2 true LUC00159I2 (fr) 2021-07-06

Family

ID=43735742

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00159C LUC00159I2 (fr) 2010-01-14 2020-06-16

Country Status (33)

Country Link
US (2) US8609862B2 (fr)
EP (2) EP3527208A1 (fr)
JP (4) JP5602250B2 (fr)
KR (1) KR101412206B1 (fr)
CN (2) CN105440038A (fr)
AU (1) AU2011205290C1 (fr)
BR (1) BR112012017458B1 (fr)
CA (1) CA2786443C (fr)
CL (1) CL2012001961A1 (fr)
CY (2) CY1121320T1 (fr)
DK (1) DK2523731T3 (fr)
ES (1) ES2707596T3 (fr)
HR (1) HRP20190064T1 (fr)
HU (2) HUE041967T2 (fr)
IL (1) IL220804A0 (fr)
LT (2) LT2523731T (fr)
LU (1) LUC00159I2 (fr)
MA (1) MA33904B1 (fr)
ME (1) ME03371B (fr)
MX (2) MX2012008212A (fr)
NL (1) NL301043I2 (fr)
NO (1) NO2020012I1 (fr)
NZ (1) NZ601077A (fr)
PH (1) PH12012501422B1 (fr)
PL (1) PL2523731T3 (fr)
PT (1) PT2523731T (fr)
RS (1) RS58234B1 (fr)
SG (1) SG182393A1 (fr)
SI (1) SI2523731T1 (fr)
TN (1) TN2012000352A1 (fr)
TR (1) TR201900515T4 (fr)
WO (1) WO2011088188A1 (fr)
ZA (1) ZA201205058B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5602250B2 (ja) * 2010-01-14 2014-10-08 ノバルティス アーゲー 副腎ホルモン修飾剤の使用
EP2582375A4 (fr) 2010-06-16 2013-12-25 Embera Neurotherapeutics Inc Compositions et procédés pour le traitement de l'addiction, des troubles psychiatriques, et d'une maladie neurodégénérative
AR086665A1 (es) 2011-06-14 2014-01-15 Lilly Co Eli Inhibidor de aldosterona sintasa y composiciones farmaceuticas
US9351973B2 (en) 2011-09-22 2016-05-31 Merck Sharp & Dohme Corp. Pyrazolopyridyl compounds as aldosterone synthase inhibitors
EP2757882B1 (fr) 2011-09-22 2020-11-04 Merck Sharp & Dohme Corp. Composés imidazopyridyliques utilisables en tant qu'inhibiteurs de l'aldostérone synthase
EP2757883B1 (fr) 2011-09-22 2021-01-13 Merck Sharp & Dohme Corp. Composés triazolopyridyle à utiliser en tant qu'inhibiteurs de l'aldostérone synthase
EP2804863B1 (fr) * 2012-01-17 2015-12-02 Novartis AG Nouvelles formes et sels d'un inhibiteur de l'aldostérone synthase imidazole dihydropyrrolo [1,2-c]ou ou de l'inhibiteur de l'aromatase
EP2836228B1 (fr) * 2012-04-12 2024-03-20 Novartis AG Combinaison d'analogues de la somatostatine et d'inhibiteurs de la 11-bêta-hydroxylase
CA2886117C (fr) 2012-10-05 2022-05-31 Merck Sharp & Dohme Corp. Composes d'indoline utilises comme inhibiteurs de l'aldosterone synthase
JP2015093832A (ja) * 2013-11-08 2015-05-18 日本メジフィジックス株式会社 放射性ハロゲン標識化合物又はその塩、これを含む医薬
PE20170201A1 (es) * 2014-07-07 2017-04-08 Novartis Ag Formas de dosificacion farmaceutica
WO2016048984A1 (fr) * 2014-09-25 2016-03-31 Cortendo Ab (Publ) Méthodes et compositions pour le traitement du syndrome de cushing basées sur le 2s,4r kétoconazole
EP3250555B1 (fr) * 2015-01-29 2021-03-03 Recordati AG Procédé de production de dérivés d'imidazoles condensés
US20160287565A1 (en) 2015-04-06 2016-10-06 Millendo Therapeutics, Inc. Combination therapy for treating disorders associated with excess cortisol production
CN108025008A (zh) * 2015-06-22 2018-05-11 安比拉神经疗法公司 用于治疗物质使用障碍、成瘾和精神病的组合物和方法
WO2018165649A1 (fr) 2017-03-10 2018-09-13 Embera Neurotherapeutics, Inc. Compositions pharmaceutiques et leurs utilisations

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889861A (en) * 1982-12-21 1989-12-26 Ciba-Geigy Corp. Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors
US4814333A (en) 1987-07-28 1989-03-21 The Trustees Of Dartmouth College Method for treatment of hypercortisolemic, depressed patients
US5503843A (en) 1994-04-22 1996-04-02 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
US5658881A (en) 1994-10-14 1997-08-19 Twk, Inc. Method for topical inhibition of the metabolic activity of cytochrome P450
DE19814087A1 (de) * 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
US7417038B1 (en) 1998-10-15 2008-08-26 Imperial Innovations Limited Methods of treating cachexia
EP1392676B1 (fr) * 2001-02-16 2006-12-13 Aventis Pharmaceuticals Inc. Nouveaux derives d'uree heterocycliques et leur utilisation en tant que ligands des recepteurs de la dopamine d3
TWI263640B (en) 2001-12-19 2006-10-11 Bristol Myers Squibb Co Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
GB0212412D0 (en) * 2002-05-29 2002-07-10 Novartis Ag Combination of organic compounds
JP5138875B2 (ja) 2005-07-19 2013-02-06 株式会社デンソー センサ装置
GT200600381A (es) * 2005-08-25 2007-03-28 Compuestos organicos
TW200804378A (en) 2005-12-09 2008-01-16 Speedel Experimenta Ag Organic compounds
CA2645678A1 (fr) 2006-03-16 2007-09-20 Yeda Research And Development Co. Ltd. Procede et composition pour la protection du tissu neuronal de degats induits par des niveaux eleves de glutamate
MX2008015008A (es) 2006-05-26 2008-12-05 Novartis Ag INHIBIDORES DE SINTASA DE ALDOSTERONA Y/O DE 11ß-HIDROXILASA.
EP1886695A1 (fr) 2006-06-27 2008-02-13 Speedel Experimenta AG Combinaisons pharmacéutiques avec inhibiteurs de l'aldosterone synthase et antagonistes du recepteur de glucocorticoides où inhibiteurs de la synthese de cortisol où antagonistes du facteur de libération de la corticotropine
CA2660701A1 (fr) * 2006-08-25 2008-03-06 Novartis Ag Derives d'imidazole fusionnes destines a traiter les troubles medies par l'aldosterone synthase et/ou par 11-beta-hydroxylase et/ou aromatase
KR20090090395A (ko) * 2006-12-18 2009-08-25 노파르티스 아게 4-이미다졸릴-1,2,3,4-테트라히드로퀴놀린 유도체 및 알도스테론/11-베타-히드록실라제 억제제로서의 그의 용도
EP2095819A1 (fr) * 2008-02-28 2009-09-02 Maastricht University Dérivés de N-benzyle imidazole et leur utilisation comme inhibiteurs de l'aldosterone synthase
AR072297A1 (es) 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
JP5602250B2 (ja) * 2010-01-14 2014-10-08 ノバルティス アーゲー 副腎ホルモン修飾剤の使用
EP2804863B1 (fr) * 2012-01-17 2015-12-02 Novartis AG Nouvelles formes et sels d'un inhibiteur de l'aldostérone synthase imidazole dihydropyrrolo [1,2-c]ou ou de l'inhibiteur de l'aromatase
EP2836228B1 (fr) * 2012-04-12 2024-03-20 Novartis AG Combinaison d'analogues de la somatostatine et d'inhibiteurs de la 11-bêta-hydroxylase

Also Published As

Publication number Publication date
NL301043I1 (nl) 2020-06-17
CN102711916B (zh) 2015-09-02
US8609862B2 (en) 2013-12-17
BR112012017458B1 (pt) 2020-10-20
ZA201205058B (en) 2014-04-30
IL220804A0 (en) 2012-08-30
MA33904B1 (fr) 2013-01-02
WO2011088188A1 (fr) 2011-07-21
JP2018150326A (ja) 2018-09-27
LT2523731T (lt) 2019-02-11
ME03371B (fr) 2020-01-20
CL2012001961A1 (es) 2013-03-22
KR20120116482A (ko) 2012-10-22
RU2598708C2 (ru) 2016-09-27
NO2020012I1 (no) 2020-06-09
MX2012008212A (es) 2012-08-03
NL301043I2 (nl) 2020-07-06
EP2523731A1 (fr) 2012-11-21
HUS000508I2 (hu) 2021-03-29
CN105440038A (zh) 2016-03-30
LTC2523731I2 (lt) 2022-05-10
CY1121320T1 (el) 2020-05-29
HUS2000018I1 (hu) 2020-07-28
CN102711916A (zh) 2012-10-03
JP2015013859A (ja) 2015-01-22
HRP20190064T1 (hr) 2019-03-08
PH12012501422B1 (en) 2018-09-12
US20140171392A1 (en) 2014-06-19
SI2523731T1 (sl) 2019-02-28
US20120295888A1 (en) 2012-11-22
RS58234B1 (sr) 2019-03-29
LTPA2020512I1 (lt) 2020-07-27
BR112012017458A2 (pt) 2017-12-19
CY2020018I2 (el) 2020-11-25
JP2013517280A (ja) 2013-05-16
TN2012000352A1 (en) 2014-01-30
EP3527208A1 (fr) 2019-08-21
TR201900515T4 (tr) 2019-02-21
JP2017002063A (ja) 2017-01-05
KR101412206B1 (ko) 2014-06-25
CY2020018I1 (el) 2020-11-25
NZ601077A (en) 2014-07-25
CA2786443C (fr) 2018-12-11
PH12012501422A1 (en) 2012-10-22
CA2786443A1 (fr) 2011-07-21
RU2012134510A (ru) 2014-02-20
AU2011205290A1 (en) 2012-08-02
MX354022B (es) 2018-02-08
PT2523731T (pt) 2019-01-21
SG182393A1 (en) 2012-08-30
AU2011205290B2 (en) 2014-06-26
LUC00159I1 (fr) 2020-06-16
HUE041967T2 (hu) 2019-06-28
JP6425688B2 (ja) 2018-11-21
DK2523731T3 (en) 2019-02-04
EP2523731B1 (fr) 2018-10-24
PL2523731T3 (pl) 2019-04-30
ES2707596T3 (es) 2019-04-04
JP6181610B2 (ja) 2017-08-16
US9434754B2 (en) 2016-09-06
AU2011205290C1 (en) 2014-11-06
JP5602250B2 (ja) 2014-10-08

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