LUC00327I2 - - Google Patents

Info

Publication number: LUC00327I2
Authority: LU; Luxembourg

Application number

LU00327C

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-16

Filing date

2023-12-27

Publication date

2026-02-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40251685&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00327(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2023-12-27 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2026-02-02 Publication of LUC00327I2 publication Critical patent/LUC00327I2/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

LU00327C 2007-10-16 2023-12-27 LUC00327I2 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US98039707P	2007-10-16	2007-10-16

Publications (1)

Publication Number	Publication Date
LUC00327I2 true LUC00327I2 (fr)	2026-02-02

Family

ID=40251685

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LU00326C LUC00326I9 (fr)	2007-10-16	2023-12-27
LU00327C LUC00327I2 (fr)	2007-10-16	2023-12-27

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
LU00326C LUC00326I9 (fr)	2007-10-16	2023-12-27

Country Status (40)

Country	Link
US (4)	US8268800B2 (fr)
EP (2)	EP2447272B1 (fr)
JP (2)	JP5496899B2 (fr)
KR (1)	KR101543049B1 (fr)
CN (1)	CN101827856B (fr)
AT (1)	ATE548374T1 (fr)
BR (1)	BRPI0818672B8 (fr)
CA (1)	CA2702274C (fr)
CO (1)	CO6270330A2 (fr)
CR (1)	CR11427A (fr)
CY (3)	CY1112781T1 (fr)
DK (1)	DK2207786T3 (fr)
EA (1)	EA018757B1 (fr)
EC (1)	ECSP10010095A (fr)
ES (2)	ES2616566T3 (fr)
FI (2)	FIC20230040I1 (fr)
FR (2)	FR23C1052I2 (fr)
GT (1)	GT201000088A (fr)
HR (1)	HRP20120419T1 (fr)
HU (2)	HUS2300045I1 (fr)
IL (1)	IL204732A (fr)
JO (1)	JO2778B1 (fr)
LT (2)	LTC2207786I2 (fr)
LU (2)	LUC00326I9 (fr)
ME (1)	ME00997B (fr)
MX (1)	MX2010004109A (fr)
MY (1)	MY147970A (fr)
NI (1)	NI201000055A (fr)
NL (2)	NL301256I2 (fr)
NO (2)	NO2023047I1 (fr)
NZ (1)	NZ584229A (fr)
PL (1)	PL2207786T3 (fr)
PT (1)	PT2207786E (fr)
RS (1)	RS52323B (fr)
SA (1)	SA08290661B1 (fr)
SI (1)	SI2207786T1 (fr)
TW (1)	TWI445539B (fr)
UA (1)	UA99476C2 (fr)
WO (1)	WO2009052287A1 (fr)
ZA (1)	ZA201002178B (fr)

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HUE055911T2 (hu)	2008-05-15	2021-12-28	Celgene Corp	Citidin-analógokat tartalmazó orális készítmények, és eljárások azok alkalmazására
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ES2628609T3 (es) *	2009-04-06	2017-08-03	Otsuka Pharmaceutical Co., Ltd.	Combinación de fármacos antineoplásicos a base de citidina con inhibidor de citidina deaminasa y uso del mismo en el tratamiento de cáncer
EP2417146B1 (fr) *	2009-04-06	2016-07-13	Otsuka Pharmaceutical Co., Ltd.	(2'-desoxy-ribofuranosyl)-1,3,4,7-tetrahydro-(1,3)diazepin-2-on derivate zur behandlung von krebs
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SI2709613T2 (sl)	2011-09-16	2020-12-31	Gilead Pharmasset LLC c/o Gilead Sciences, Inc.	Postopki za zdravljenje HCV
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JP2016529293A (ja)	2013-08-27	2016-09-23	ギリアドファーマセットエルエルシー	２つの抗ウイルス化合物の組合せ製剤
RU2681939C2 (ru)	2013-10-29	2019-03-14	Оцука Фармасьютикал Ко., Лтд.	Путь синтезирования 2'-дезокси-2'2'-дифтортетрагидроуридинов
JP6783224B2 (ja)	2014-04-04	2020-11-11	デルマーファーマシューティカルズ	肺の非小細胞癌腫及び卵巣癌を処置するためのジアンヒドロガラクチトール及びその類縁体又は誘導体の使用
US10034872B2 (en)	2014-08-22	2018-07-31	Celgene Corporation	Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies
CA3007357C (fr)	2015-12-03	2023-12-05	Epidestiny, Inc.	Compositions contenant de la decitabine, de la 5-azacytidine et de la tetrahydrouridine
WO2017158396A1 (fr)	2016-03-16	2017-09-21	INSERM (Institut National de la Santé et de la Recherche Médicale)	Inhibiteurs de cytidine désaminase pour le traitement du cancer du pancréas
AU2019216531A1 (en)	2018-02-02	2020-09-24	Maverix Oncology, Inc.	Small molecule drug conjugates of gemcitabine monophosphate
WO2020047177A1 (fr) *	2018-08-28	2020-03-05	Essenlix Corporation	Amélioration de la précision d'un dosage
US11224610B2 (en) *	2018-09-19	2022-01-18	Otsuka Pharmaceutical Co., Ltd.	Low dose combination CDA substrate drug/cedazuridine with extended administration
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JO2778B1 (en)	2007-10-16	2014-03-15	ايساي انك	Certain Compounds, Compositions and Methods
WO2010047698A1 (fr)	2008-10-22	2010-04-29	University Of Alabama At Birmingham	Répression de maladies auto-immunes par un inhibiteur de la cytidine désaminase induite par activation
ES2628609T3 (es)	2009-04-06	2017-08-03	Otsuka Pharmaceutical Co., Ltd.	Combinación de fármacos antineoplásicos a base de citidina con inhibidor de citidina deaminasa y uso del mismo en el tratamiento de cáncer
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EP2417146B1 (fr)	2009-04-06	2016-07-13	Otsuka Pharmaceutical Co., Ltd.	(2'-desoxy-ribofuranosyl)-1,3,4,7-tetrahydro-(1,3)diazepin-2-on derivate zur behandlung von krebs
WO2010118010A1 (fr)	2009-04-06	2010-10-14	Eisai Inc.	Association de décitabine et d'un inhibiteur de la cytidine désaminase et utilisation de cette association dans le traitement du cancer

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Also Published As

Publication number	Publication date
ECSP10010095A (es)	2010-07-30
SA08290661B1 (ar)	2012-06-10
JP5859588B2 (ja)	2016-02-10
LTPA2023539I1 (fr)	2024-02-26
TWI445539B (zh)	2014-07-21
EP2447272A1 (fr)	2012-05-02
FR23C1052I2 (fr)	2025-02-07
US20090137521A1 (en)	2009-05-28
HK1146410A1 (en)	2011-06-03
JP2011500713A (ja)	2011-01-06
NL301256I1 (fr)	2024-01-03
US20120289475A1 (en)	2012-11-15
BRPI0818672B1 (pt)	2020-10-20
HRP20120419T1 (hr)	2012-07-31
WO2009052287A1 (fr)	2009-04-23
FR23C1051I1 (fr)	2024-01-26
JP5496899B2 (ja)	2014-05-21
IL204732A0 (en)	2010-11-30
AU2008312435A1 (en)	2009-04-23
JP2014177455A (ja)	2014-09-25
GT201000088A (es)	2012-03-13
KR20100091978A (ko)	2010-08-19
CA2702274A1 (fr)	2009-04-23
EP2207786A1 (fr)	2010-07-21
EA018757B1 (ru)	2013-10-30
CR11427A (es)	2010-08-16
TW200924786A (en)	2009-06-16
HUS2300044I1 (hu)	2024-01-28
CY2023029I1 (el)	2024-02-16
LUC00326I9 (fr)	2026-02-25
ME00997B (fr)	2012-10-20
JO2778B1 (en)	2014-03-15
EP2447272B1 (fr)	2017-02-01
NO2023047I1 (no)	2023-12-21
PT2207786E (pt)	2012-05-28
US20140186335A1 (en)	2014-07-03
NZ584229A (en)	2012-06-29
AU2008312435B2 (en)	2014-04-17
FR23C1051I2 (fr)	2025-02-07
US8951987B2 (en)	2015-02-10
CO6270330A2 (es)	2011-04-20
AU2008312435A8 (en)	2014-07-24
MX2010004109A (es)	2010-08-10
US9567363B2 (en)	2017-02-14
BRPI0818672B8 (pt)	2021-05-25
HUS2300045I1 (hu)	2024-01-28
LTC2207786I2 (fr)	2025-09-10
US20150210730A1 (en)	2015-07-30
ZA201002178B (en)	2011-05-25
LUC00326I2 (fr)	2026-02-02
FR23C1052I1 (fr)	2024-01-26
ES2384011T3 (es)	2012-06-28
ES2616566T3 (es)	2017-06-13
CY1112781T1 (el)	2016-02-10
FIC20230039I1 (fi)	2023-12-22
EP2207786B1 (fr)	2012-03-07
BRPI0818672A2 (pt)	2015-04-14
US8618075B2 (en)	2013-12-31
PL2207786T3 (pl)	2012-09-28
CN101827856A (zh)	2010-09-08
NI201000055A (es)	2010-08-13
US8268800B2 (en)	2012-09-18
SI2207786T1 (sl)	2012-10-30
FIC20230040I1 (fi)	2023-12-22
CN101827856B (zh)	2013-02-06
EA201000642A1 (ru)	2010-10-29
DK2207786T3 (da)	2012-06-18
IL204732A (en)	2013-07-31
NL301256I2 (nl)	2024-01-11
NL301257I2 (nl)	2025-11-06
NO2023048I1 (en)	2023-12-21
KR101543049B1 (ko)	2015-08-07
CY2023028I1 (el)	2024-02-16
CA2702274C (fr)	2015-12-29
RS52323B (sr)	2012-12-31
MY147970A (en)	2013-02-28
UA99476C2 (en)	2012-08-27
LTPA2023538I1 (fr)	2024-02-26
ATE548374T1 (de)	2012-03-15

Publication	Publication Date	Title
NL301256I1 (fr)	2024-01-03
BRPI0819773A2 (fr)	2009-06-04
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