LV10725B - Brain derived neurotrophic factor - Google Patents

Brain derived neurotrophic factor Download PDF

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Publication number
LV10725B
LV10725B LVP-93-1133A LV931133A LV10725B LV 10725 B LV10725 B LV 10725B LV 931133 A LV931133 A LV 931133A LV 10725 B LV10725 B LV 10725B
Authority
LV
Latvia
Prior art keywords
bdnf
ngf
disease
neurons
protein
Prior art date
Application number
LVP-93-1133A
Other languages
English (en)
Latvian (lv)
Other versions
LV10725A (lv
Inventor
Hyman Carolyn
Alderson Ralph
Yancopoulos George
Barde Yves-Alain
Thoenen Hans Friedrich Erwin
Hohn Andreas
Lottspeich Friedrich
Ronald M Lindsay
Hofer Magdalena
Leibrock Joachim
Edgar David
Hengerer Bastian
Dan B Lindholm
Zafra Francisco
Original Assignee
Max Planck Ges Zur Firderung D
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/400,591 external-priority patent/US5180820A/en
Application filed by Max Planck Ges Zur Firderung D, Regeneron Pharma filed Critical Max Planck Ges Zur Firderung D
Publication of LV10725A publication Critical patent/LV10725A/xx
Publication of LV10725B publication Critical patent/LV10725B/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LVP-93-1133A 1989-08-30 1993-10-06 Brain derived neurotrophic factor LV10725B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/400,591 US5180820A (en) 1989-08-30 1989-08-30 Brain-derived neurotrophic factor
US07/570,657 US5229500A (en) 1989-08-30 1990-08-20 Brain derived neurotrophic factor
PCT/US1990/004915 WO1991003568A1 (en) 1989-08-30 1990-08-29 Brain derived neurotrophic factor

Publications (2)

Publication Number Publication Date
LV10725A LV10725A (lv) 1995-06-20
LV10725B true LV10725B (en) 1995-12-20

Family

ID=27017110

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-1133A LV10725B (en) 1989-08-30 1993-10-06 Brain derived neurotrophic factor

Country Status (20)

Country Link
US (2) US5229500A (de)
EP (1) EP0440777B1 (de)
KR (1) KR100188189B1 (de)
CN (1) CN1124343C (de)
AT (1) ATE148921T1 (de)
AU (1) AU647412B2 (de)
CA (1) CA2040412C (de)
DE (1) DE69029934T2 (de)
DK (1) DK0440777T3 (de)
ES (1) ES2098271T3 (de)
FI (1) FI105342B (de)
HK (1) HK1006578A1 (de)
IE (1) IE903128A1 (de)
IL (1) IL95512A0 (de)
LV (1) LV10725B (de)
NO (1) NO303584B1 (de)
PT (1) PT95152B (de)
SG (1) SG46954A1 (de)
SK (1) SK422990A3 (de)
WO (1) WO1991003568A1 (de)

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Also Published As

Publication number Publication date
AU647412B2 (en) 1994-03-24
IE903128A1 (en) 1991-03-13
PT95152A (pt) 1991-05-22
NO911689D0 (no) 1991-04-29
NO303584B1 (no) 1998-08-03
KR100188189B1 (en) 1999-06-01
EP0440777A1 (de) 1991-08-14
IL95512A0 (en) 1991-06-30
US5229500A (en) 1993-07-20
FI912104A0 (fi) 1991-04-30
FI105342B (fi) 2000-07-31
SK279668B6 (sk) 1999-02-11
PT95152B (pt) 1998-06-30
WO1991003568A1 (en) 1991-03-21
ATE148921T1 (de) 1997-02-15
US5438121A (en) 1995-08-01
SG46954A1 (en) 1998-03-20
EP0440777B1 (de) 1997-02-12
SK422990A3 (en) 1999-02-11
LV10725A (lv) 1995-06-20
ES2098271T3 (es) 1997-05-01
AU6337390A (en) 1991-04-08
CN1124343C (zh) 2003-10-15
KR920701432A (ko) 1992-08-11
DE69029934T2 (de) 1997-07-24
HK1006578A1 (en) 1999-03-05
CA2040412C (en) 2003-03-18
CN1052142A (zh) 1991-06-12
NO911689L (no) 1991-06-25
EP0440777A4 (en) 1992-05-13
DK0440777T3 (da) 1997-04-21
CA2040412A1 (en) 1991-03-01
DE69029934D1 (de) 1997-03-27

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