LV11002B - A solvent-free pharmaceutical preparation to be administered orally having delayed release of active compound and method of preparation thereof lísungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzígerter wirkstofffreisetzung und verfahren zu deren herstellung - Google Patents

A solvent-free pharmaceutical preparation to be administered orally having delayed release of active compound and method of preparation thereof lísungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzígerter wirkstofffreisetzung und verfahren zu deren herstellung Download PDF

Info

Publication number
LV11002B
LV11002B LVP-95-164A LV950164A LV11002B LV 11002 B LV11002 B LV 11002B LV 950164 A LV950164 A LV 950164A LV 11002 B LV11002 B LV 11002B
Authority
LV
Latvia
Prior art keywords
active ingredient
pharmaceutical preparation
oral administration
slow release
der
Prior art date
Application number
LVP-95-164A
Other languages
English (en)
Latvian (lv)
Other versions
LV11002A (lv
Inventor
Ulrich Muench
Hans-Juergen Mika
Bernhard Emschermann
Rainer Schmidt
Bernhard Sczepanik
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6415859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV11002(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of LV11002A publication Critical patent/LV11002A/xx
Publication of LV11002B publication Critical patent/LV11002B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
LVP-95-164A 1990-10-08 1995-06-09 A solvent-free pharmaceutical preparation to be administered orally having delayed release of active compound and method of preparation thereof lísungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzígerter wirkstofffreisetzung und verfahren zu deren herstellung LV11002B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4031881A DE4031881C2 (de) 1990-10-08 1990-10-08 Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung

Publications (2)

Publication Number Publication Date
LV11002A LV11002A (lv) 1996-02-20
LV11002B true LV11002B (en) 1996-06-20

Family

ID=6415859

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-164A LV11002B (en) 1990-10-08 1995-06-09 A solvent-free pharmaceutical preparation to be administered orally having delayed release of active compound and method of preparation thereof lísungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzígerter wirkstofffreisetzung und verfahren zu deren herstellung

Country Status (24)

Country Link
US (1) US5453283A (fr)
EP (1) EP0552227B2 (fr)
JP (1) JP3233929B2 (fr)
KR (1) KR0166599B1 (fr)
AT (1) ATE116843T1 (fr)
CA (1) CA2093666C (fr)
CZ (1) CZ284923B6 (fr)
DE (2) DE4031881C2 (fr)
DK (1) DK0552227T4 (fr)
ES (1) ES2067250T5 (fr)
FI (1) FI108401B (fr)
GR (1) GR3015131T3 (fr)
HR (1) HRP920960B1 (fr)
HU (2) HUT64211A (fr)
IE (1) IE76142B1 (fr)
LV (1) LV11002B (fr)
PL (1) PL167593B1 (fr)
PT (1) PT99168B (fr)
RU (1) RU2101009C1 (fr)
SI (1) SI9111618B (fr)
SK (1) SK279446B6 (fr)
UA (1) UA26449C2 (fr)
WO (1) WO1992005774A1 (fr)
YU (1) YU48766B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2128499C1 (ru) * 1992-12-23 1999-04-10 Сайтек С.Р.Л. Способ получения фармацевтических форм с контролированным высвобождением действующего вещества и формы, полученные данным способом
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
EP0818990A1 (fr) * 1995-04-03 1998-01-21 Abbott Laboratories Melanges homogenes de medicaments fondant a basse temperature et d'additifs, destines a une liberation lente
HRP970485A2 (en) 1996-09-13 1998-08-31 Joerg Rosenberg Process for producing solid pharmaceutical forms
US5851555A (en) * 1997-08-15 1998-12-22 Fuisz Technologies Ltd. Controlled release dosage forms containing water soluble drugs
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE10029201A1 (de) 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
CA2421885A1 (fr) * 2000-10-27 2002-05-02 Nitromed, Inc. Methodes de traitement de maladies vasculaires caracterisees par une insuffisance en monoxyde d'azote
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
RU2267318C1 (ru) * 2004-05-25 2006-01-10 Закрытое акционерное общество "ФАРМАПЭК" Пролонгированный антиангинальный препарат изосорбида динитрата и способ его получения
MY148074A (en) * 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
US7241805B2 (en) 2005-06-27 2007-07-10 Biovail Laboratories, Inc. Modified release formulations of a bupropion salt
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
KR101659983B1 (ko) 2012-12-31 2016-09-26 주식회사 삼양바이오팜 용융 압출된 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제
WO2017086835A1 (fr) * 2015-11-17 2017-05-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Composition pharmaceutique possédant un effet thérapeutique vis-à-vis des maladies démyélinisantes (et variantes)
AU2018360383A1 (en) 2017-11-02 2020-05-21 Natureceuticals Sdn. Bhd. Extract of orthosiphon stamineus, formulations, and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297357A (fr) * 1962-08-31
US3308217A (en) * 1965-02-09 1967-03-07 Lowy Lawrence Method of granulating materials for subsequent forming into tablets
ES403326A1 (es) * 1971-06-04 1975-05-01 Boehringer Mannheim Gmbh Procedimiento para la granulacion de masas para tabletas enforma de polvo.
FR2581541B1 (fr) * 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
US5246714A (en) * 1985-10-11 1993-09-21 Aktiebolaget Hassle Drug preparation
DE3612211A1 (de) * 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
DE3743946A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
DE3812567A1 (de) * 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
DE3830353A1 (de) * 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline

Also Published As

Publication number Publication date
FI108401B (fi) 2002-01-31
UA26449C2 (uk) 1999-08-30
IE76142B1 (en) 1997-10-08
GR3015131T3 (en) 1995-05-31
WO1992005774A1 (fr) 1992-04-16
YU48766B (sh) 1999-12-27
SK279446B6 (sk) 1998-11-04
SI9111618B (sl) 1999-08-31
EP0552227A1 (fr) 1993-07-28
YU161891A (sh) 1994-06-10
PL167593B1 (pl) 1995-09-30
DE4031881A1 (de) 1992-04-09
HUT64211A (en) 1993-12-28
HRP920960A2 (en) 1995-08-31
DE4031881C2 (de) 1994-02-24
SI9111618A (en) 1997-12-31
JP3233929B2 (ja) 2001-12-04
DK0552227T4 (da) 1999-07-19
FI931576L (fi) 1993-04-07
CS305091A3 (en) 1992-04-15
PT99168A (pt) 1992-09-30
US5453283A (en) 1995-09-26
LV11002A (lv) 1996-02-20
JPH06501685A (ja) 1994-02-24
HU211845A9 (en) 1995-12-28
DE59104271D1 (de) 1995-02-23
FI931576A0 (fi) 1993-04-07
DK0552227T3 (da) 1995-03-27
EP0552227B2 (fr) 1998-11-04
CA2093666A1 (fr) 1992-04-09
HU9300995D0 (en) 1993-07-28
ES2067250T3 (es) 1995-03-16
KR930701963A (ko) 1993-09-08
ES2067250T5 (es) 1999-02-01
HRP920960B1 (en) 1998-10-31
KR0166599B1 (ko) 1999-01-15
EP0552227B1 (fr) 1995-01-11
RU2101009C1 (ru) 1998-01-10
ATE116843T1 (de) 1995-01-15
CA2093666C (fr) 1998-05-19
CZ284923B6 (cs) 1999-04-14
IE913592A1 (en) 1992-04-08
PT99168B (pt) 1999-04-30

Similar Documents

Publication Publication Date Title
AT392901B (de) Verfahren zur herstellung einer granulaeren form mit verzoegerter freisetzung von pharmazeutisch wirksamen substanzen
DE69629755T3 (de) Irbesartanhaltiges Arzneimittel
DE69213800T2 (de) Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze
EP0552227B2 (fr) Preparation pharmaceutique exempte de solvants, administree oralement, a liberation retardee du principe actif, ainsi que procede pour sa fabrication
DE69305335T2 (de) Pharmazeutische zubereitung und verfahren für ihre herstellung
DE69212879T2 (de) Magensaftstabile pharmazeutische Formulierungen zur Oral Verbreichung von Gallensäuren
DE69418252T2 (de) Stabilisierte, feste pharmazeutische Zubereitung, die Dextromethorphan Phenylpropanolamine und Coffein enthält
CH658188A5 (de) Lagerstabile schnellzerfallende pharmazeutische presslinge.
EP1165081B1 (fr) Procede de preparation de compositions pharmaceutiques de tolperisone pour administration orale
DE2224534B2 (de) Pharmazeutisches praeparat mit langsamer wirkstoffabgabe
DE4332394A1 (de) Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
EP0715846A1 (fr) Composition pharmaceutique pour administration orale contenant des aminoacides
DE3314003A1 (de) Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
EP0715857A2 (fr) Composition pharmaceutique pour application orale contenant un acide aminé hydrosoluble comme accélérateur de la désintégration
DE3520184A1 (de) Neue galenische retardform
DE3719818A1 (de) Pharmazeutische zusammensetzungen
EP0796103A1 (fr) Utilisation de l'encens pour le traitement de la maladie d'alzheimer
EP0167909B2 (fr) Préparations pharmaceutiques solides contenant dihydropyridine et procédé pour leur préparation
EP0855183A2 (fr) Fabrication de préparations masquant le mauvais goût de dérivés quinoloniques antibactériens
DE68905573T2 (de) Leicht absorbierbare nb-818 enthaltende arzneizubereitung.
DE60005012T2 (de) Geschmacksmaskierte zubereitungen
DE10061137B4 (de) Neue pharmazeutische Zubereitung
DE3602577A1 (de) 9,10-dihydrogenierte ergotalkaloide enthaltende pharmazeutische zusammensetzungen
DE2950154C2 (fr)
EP1663160B1 (fr) Forme galenique multiparticulaire orale formulee par fusion