LV11273A - Naftohinoni pneumocystis carinii infekciju arstesanai un profilaksei - Google Patents
Naftohinoni pneumocystis carinii infekciju arstesanai un profilakseiInfo
- Publication number
- LV11273A LV11273A LV950113A LV950113A LV11273A LV 11273 A LV11273 A LV 11273A LV 950113 A LV950113 A LV 950113A LV 950113 A LV950113 A LV 950113A LV 11273 A LV11273 A LV 11273A
- Authority
- LV
- Latvia
- Prior art keywords
- group
- treatment
- infections
- pneumocystis carinii
- naftoquinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/12—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/24—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
- C07C225/26—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
- C07C225/30—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/24—Quinones containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888819478A GB8819478D0 (en) | 1988-08-16 | 1988-08-16 | Medicaments |
| GB888819479A GB8819479D0 (en) | 1988-08-16 | 1988-08-16 | Medicaments |
| GB888819480A GB8819480D0 (en) | 1988-08-16 | 1988-08-16 | Medicaments |
| GB888819477A GB8819477D0 (en) | 1988-08-16 | 1988-08-16 | Medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV11273A true LV11273A (lv) | 1996-06-20 |
| LV11273B LV11273B (en) | 1996-10-20 |
Family
ID=27450160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-95-113A LV11273B (en) | 1988-08-16 | 1995-04-26 | Naphthoquinones for the treatment and prophylaxis of pneumocystis carinii infections |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP0580185B1 (lv) |
| JP (1) | JP2804302B2 (lv) |
| AT (1) | ATE178311T1 (lv) |
| AU (1) | AU633836B2 (lv) |
| CA (1) | CA1329621C (lv) |
| CY (1) | CY1863A (lv) |
| DE (2) | DE68928964T2 (lv) |
| DK (1) | DK175787B1 (lv) |
| ES (2) | ES2052012T3 (lv) |
| FI (1) | FI893835A7 (lv) |
| HK (1) | HK103395A (lv) |
| HU (1) | HU208624B (lv) |
| IE (1) | IE65715B1 (lv) |
| IL (1) | IL91308A (lv) |
| LV (1) | LV11273B (lv) |
| MX (1) | MX9202995A (lv) |
| NZ (1) | NZ230313A (lv) |
| PT (2) | PT91456B (lv) |
| SA (1) | SA95160138B1 (lv) |
| SG (1) | SG23618G (lv) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0567162A1 (en) * | 1989-09-22 | 1993-10-27 | The Wellcome Foundation Limited | Medicaments for the treatment of toxoplasmosis |
| GB8921516D0 (en) * | 1989-09-22 | 1989-11-08 | Wellcome Found | Medicaments |
| GB9103075D0 (en) * | 1991-02-13 | 1991-03-27 | Washington Odur Ayuko | Trinitrobenzene derivatives and their therapeutic use |
| GB9121316D0 (en) * | 1991-10-09 | 1991-11-20 | Wellcome Found | Heterocyclic compounds |
| GB9126874D0 (en) * | 1991-12-18 | 1992-02-19 | Wellcome Found | Medicaments |
| GB9207517D0 (en) * | 1992-04-06 | 1992-05-20 | Wellcome Found | Heterocyclic compounds |
| GB9216859D0 (en) * | 1992-08-07 | 1992-09-23 | Wellcome Found | Medicaments |
| GB9224739D0 (en) * | 1992-11-26 | 1993-01-13 | Wellcome Found | Medicaments |
| GB9226905D0 (en) | 1992-12-24 | 1993-02-17 | Wellcome Found | Pharmaceutical preparation |
| WO1996013254A1 (en) * | 1994-10-26 | 1996-05-09 | Glaxo Wellcome House | Pharmaceutical composition comprising atovaquone |
| GB9613309D0 (en) * | 1996-06-25 | 1996-08-28 | Univ Sheffield | Quinone bacterial inhibitors |
| EP1779892A4 (en) * | 2004-07-30 | 2010-05-19 | Japan Health Science Found | AGAINST PROTOZOON |
| WO2009007991A2 (en) | 2007-04-19 | 2009-01-15 | Ipca Laboratories Limited | A new process for preparation of atovaquone and novel intermediates thereof |
| ITMI20070941A1 (it) * | 2007-05-09 | 2008-11-10 | Chimico Internazi0Nale S P A L | Procedimento per la preparazione di naftochinoni trans2,3-disostituiti |
| US9169232B2 (en) * | 2011-09-16 | 2015-10-27 | Alkem Laboratories Limited | 3-(5-methyl-2-oxo-l, 3-dioxol-4-yl) methyloxy-2-trans-[(4-chloro phenyl) cyclohexyl][1,4]naphthaquinone-atovaquone prodrug |
| EA201990064A1 (ru) | 2016-06-20 | 2019-05-31 | Дзе Скриппс Рисерч Инститьют | Противомалярийные композиции и варианты их применения |
| WO2022144920A1 (en) * | 2020-12-30 | 2022-07-07 | Ipca Laboratories Limited | Atovaquone prodrugs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1553424A (en) * | 1976-02-10 | 1979-09-26 | Wellcome Found | Method of treating protozal diseases |
| US4485117A (en) * | 1981-10-16 | 1984-11-27 | Hudson Alan T | Antiprotozoal compounds |
| GB8310140D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Antiprotozoal agents |
| GB8310141D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Naphthoquinone derivatives |
| GB8500292D0 (en) * | 1985-01-07 | 1985-02-13 | Wellcome Found | Treatment of babesiosis |
| DE3801743A1 (de) * | 1987-07-03 | 1989-01-19 | Bayer Ag | Schaedlingsbekaempfungsmittel auf basis von substituierten 1,4-naphthochinonen und neue substituierte 1,4-naphthochinone |
-
1989
- 1989-08-15 IE IE261689A patent/IE65715B1/en not_active IP Right Cessation
- 1989-08-15 JP JP1210543A patent/JP2804302B2/ja not_active Expired - Lifetime
- 1989-08-15 IL IL9130889A patent/IL91308A/en not_active IP Right Cessation
- 1989-08-15 CA CA000608367A patent/CA1329621C/en not_active Expired - Lifetime
- 1989-08-15 DK DK198903999A patent/DK175787B1/da not_active IP Right Cessation
- 1989-08-15 AU AU39948/89A patent/AU633836B2/en not_active Expired
- 1989-08-15 EP EP93113704A patent/EP0580185B1/en not_active Expired - Lifetime
- 1989-08-15 NZ NZ230313A patent/NZ230313A/en unknown
- 1989-08-15 AT AT93113704T patent/ATE178311T1/de not_active IP Right Cessation
- 1989-08-15 EP EP89308268A patent/EP0362996B1/en not_active Expired - Lifetime
- 1989-08-15 SG SG1995904207A patent/SG23618G/en unknown
- 1989-08-15 DE DE68928964T patent/DE68928964T2/de not_active Expired - Lifetime
- 1989-08-15 ES ES89308268T patent/ES2052012T3/es not_active Expired - Lifetime
- 1989-08-15 HU HU911004A patent/HU208624B/hu unknown
- 1989-08-15 DE DE68914930T patent/DE68914930T2/de not_active Expired - Lifetime
- 1989-08-15 FI FI893835A patent/FI893835A7/fi not_active Application Discontinuation
- 1989-08-15 ES ES93113704T patent/ES2130199T3/es not_active Expired - Lifetime
- 1989-08-16 PT PT91456A patent/PT91456B/pt not_active IP Right Cessation
-
1992
- 1992-06-18 MX MX9202995A patent/MX9202995A/es active IP Right Grant
-
1995
- 1995-04-26 LV LVP-95-113A patent/LV11273B/en unknown
- 1995-06-29 HK HK103395A patent/HK103395A/en not_active IP Right Cessation
- 1995-07-06 PT PT101734A patent/PT101734B/pt not_active IP Right Cessation
- 1995-08-05 SA SA95160138A patent/SA95160138B1/ar unknown
-
1996
- 1996-04-05 CY CY186396A patent/CY1863A/xx unknown
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