MA23411A1 - Procede de preparation de glycosides steroidiens servant d'agents hypocholesterolemique et anti atherosclereux. - Google Patents

Procede de preparation de glycosides steroidiens servant d'agents hypocholesterolemique et anti atherosclereux.

Info

Publication number
MA23411A1
MA23411A1 MA23740A MA23740A MA23411A1 MA 23411 A1 MA23411 A1 MA 23411A1 MA 23740 A MA23740 A MA 23740A MA 23740 A MA23740 A MA 23740A MA 23411 A1 MA23411 A1 MA 23411A1
Authority
MA
Morocco
Prior art keywords
atherosclereous
hypocholesterolemic
serving
agents
steroid glycosides
Prior art date
Application number
MA23740A
Other languages
English (en)
Inventor
Paul Denimmo Michael
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA23411A1 publication Critical patent/MA23411A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA23740A 1993-12-28 1994-12-27 Procede de preparation de glycosides steroidiens servant d'agents hypocholesterolemique et anti atherosclereux. MA23411A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17409993A 1993-12-28 1993-12-28

Publications (1)

Publication Number Publication Date
MA23411A1 true MA23411A1 (fr) 1995-07-01

Family

ID=22634815

Family Applications (1)

Application Number Title Priority Date Filing Date
MA23740A MA23411A1 (fr) 1993-12-28 1994-12-27 Procede de preparation de glycosides steroidiens servant d'agents hypocholesterolemique et anti atherosclereux.

Country Status (11)

Country Link
US (1) US5939398A (fr)
EP (1) EP0737202A1 (fr)
JP (1) JPH09500906A (fr)
AU (1) AU7948394A (fr)
CA (1) CA2180148A1 (fr)
CO (1) CO4230020A1 (fr)
FI (1) FI946105A7 (fr)
IL (1) IL112115A0 (fr)
MA (1) MA23411A1 (fr)
PE (1) PE4696A1 (fr)
WO (1) WO1995018143A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698527A (en) * 1995-08-08 1997-12-16 Merck & Co., Inc. Steroidal glycosides as antihyperlipidemic agents
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
PL195897B1 (pl) * 1998-03-26 2007-11-30 Phytopharm Plc Zastosowanie smilageniny
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DK1355644T3 (da) 2001-01-26 2006-10-23 Schering Corp Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
HU230253B1 (hu) 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング　コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
CN102727501A (zh) * 2002-03-27 2012-10-17 菲特法姆股份有限公司 皂角苷配基及其衍生物的用途
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives
PL210114B1 (pl) * 2002-10-28 2011-12-30 Phytopharm Plc Sposób stereospecyficznego wytwarzania 3β-hydroksy-5β-H-steroidowych sapogenin
WO2004043457A1 (fr) 2002-11-06 2004-05-27 Schering Corporation Inhibiteurs d'absorption de cholesterol pour le traitement de troubles auto-immuns
JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング　コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
CA2517571C (fr) 2003-03-07 2011-07-05 Schering Corporation Azetidinones substituees , procedes pour leur preparation, formulations et utilisations de celles-ci
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
WO1993011150A1 (fr) * 1991-11-25 1993-06-10 Pfizer Inc. Procede de preparation de glycosides de peracyle steroides
US5629295A (en) * 1992-06-26 1997-05-13 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
EP0647233A1 (fr) * 1992-06-26 1995-04-12 Pfizer Inc. PROCEDE DE SYNTHESE DE $g(b)-O-CELLOBIOSIDE HEPTAALCANOATE STEROIDIEN
AU2453295A (en) * 1994-09-20 1996-04-19 Pfizer Inc. Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor

Also Published As

Publication number Publication date
IL112115A0 (en) 1995-03-15
WO1995018143A1 (fr) 1995-07-06
PE4696A1 (es) 1996-03-09
AU7948394A (en) 1995-07-17
FI946105A0 (fi) 1994-12-27
JPH09500906A (ja) 1997-01-28
CA2180148A1 (fr) 1995-07-06
CO4230020A1 (es) 1995-10-19
EP0737202A1 (fr) 1996-10-16
US5939398A (en) 1999-08-17
FI946105A7 (fi) 1995-06-29

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