MA23893A1 - 5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant - Google Patents

5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant

Info

Publication number
MA23893A1
MA23893A1 MA24263A MA24263A MA23893A1 MA 23893 A1 MA23893 A1 MA 23893A1 MA 24263 A MA24263 A MA 24263A MA 24263 A MA24263 A MA 24263A MA 23893 A1 MA23893 A1 MA 23893A1
Authority
MA
Morocco
Prior art keywords
triazolo
pyrazolo
dihydro
preparation
compositions containing
Prior art date
Application number
MA24263A
Other languages
English (en)
Inventor
Cooper Kelvin
Jacob Duplantier Allen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA23893A1 publication Critical patent/MA23893A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA24263A 1995-06-06 1996-06-05 5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant MA23893A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB1995/000429 WO1996039408A1 (fr) 1995-06-06 1995-06-06 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2-4-TRIAZOLO[4,3-α]PYRIDINES TRICYCLIQUES
CA002223624A CA2223624C (fr) 1995-06-06 1995-06-06 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2-4-triazolo[4,3-.alpha.]pyridines tricycliques
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
MA23893A1 true MA23893A1 (fr) 1996-12-31

Family

ID=89994031

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24263A MA23893A1 (fr) 1995-06-06 1996-06-05 5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant

Country Status (43)

Country Link
US (1) US6004974A (fr)
EP (1) EP0837860B1 (fr)
JP (1) JP3107827B2 (fr)
KR (2) KR100191972B1 (fr)
CN (1) CN1061044C (fr)
AP (1) AP609A (fr)
AR (1) AR002745A1 (fr)
AT (1) ATE214700T1 (fr)
AU (1) AU694871B2 (fr)
BG (1) BG62568B1 (fr)
BR (1) BR9602627A (fr)
CA (1) CA2223624C (fr)
CO (1) CO4700460A1 (fr)
CZ (1) CZ287251B6 (fr)
DE (1) DE69525978T2 (fr)
DK (1) DK0837860T3 (fr)
DZ (1) DZ2044A1 (fr)
ES (1) ES2172583T3 (fr)
FI (1) FI114097B (fr)
HR (1) HRP960268B1 (fr)
HU (1) HUP9601541A3 (fr)
IL (1) IL118485A (fr)
IS (1) IS1913B (fr)
LV (1) LV11620B (fr)
MA (1) MA23893A1 (fr)
MX (1) MX9709897A (fr)
MY (1) MY116527A (fr)
NO (1) NO306256B1 (fr)
NZ (1) NZ286734A (fr)
OA (1) OA10458A (fr)
PL (1) PL184195B1 (fr)
PT (1) PT837860E (fr)
RO (1) RO115881B1 (fr)
RU (1) RU2161158C2 (fr)
SA (1) SA96170065B1 (fr)
SG (1) SG54341A1 (fr)
SI (1) SI9600186A (fr)
SK (1) SK282167B6 (fr)
TN (1) TNSN96083A1 (fr)
TR (1) TR199600482A1 (fr)
TW (1) TW460469B (fr)
WO (1) WO1996039408A1 (fr)
YU (1) YU49346B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
EP1380585B1 (fr) * 1999-04-30 2004-11-10 Pfizer Products Inc. Pyrazolopyridinone comme intermédiaire
US6326495B2 (en) 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
CZ302882B6 (cs) 1999-08-21 2012-01-04 Nycomed Gmbh Farmaceutický prostredek
US6555572B2 (en) 2000-03-16 2003-04-29 Inflazyme Pharmaceuticals Ltd. Benzylated PDE4 inhibitors
DE60216588T2 (de) * 2001-05-25 2007-09-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kombination eines pde4-inhibitors mit tiotropium zur behandlung obstruktiver atemwegserkrankungen
SK14312003A3 (sk) * 2001-05-25 2004-08-03 Pfizer Inc. Inhibítor PDE4 a anticholinergné činidlo v kombinácii na liečbu obštrukčných chorôb dýchacích ciest
GB0122031D0 (en) * 2001-09-12 2001-10-31 Pfizer Ltd Use of pde4 inhibitors in a dry powder inhaler
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
WO2006075748A1 (fr) * 2005-01-17 2006-07-20 Santen Pharmaceutical Co., Ltd. Agent therapeutique pour maladie conjonctivale allergique
DK1898903T3 (da) * 2005-06-10 2013-07-01 Merck Sharp & Dohme Inhibitorer af Akt-aktivitet
RU2008119323A (ru) 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Фармацевтические композиции мускаринового рецептора
RS53084B (sr) 2006-07-05 2014-06-30 Takeda Gmbh Kombinacija inhibitora hmg-coa reduktaze rosuvastatina sa inhibitorom fosfodiesteraze 4, kao što je roflumilast, roflumilast-n-oksid za lečenje inflamatornih plućnih obolenja
JP5579724B2 (ja) * 2008-10-17 2014-08-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ホスファチジルイノシトール−３−キナーゼ（ｐｉ−３キナーゼ）阻害剤としてのテトラ−アザ−複素環
WO2011067145A1 (fr) 2009-12-04 2011-06-09 Nerviano Medical Sciences S.R.L. Dérivés de tricyclopyrazole
WO2013084182A1 (fr) 2011-12-08 2013-06-13 Glenmark Pharmaceuticals S.A. Composition pharmaceutique comprenant un inhibiteur de l'enzyme pde4 et un agent analgésique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697532A (en) * 1970-08-12 1972-10-10 Squibb & Sons Inc 5-methyldipyrazolo {8 3,4-b;3{40 ,4{40 -d{9 {0 pyridin-3(2h)-ones
SU1048746A1 (ru) * 1982-01-29 1987-12-30 Институт физико-органической химии и углехимии АН УССР Гидробромид 8-адамантил-1,з-диметилимидазо 4,5-с имидазо 1,2-а пиридин-2-она,обладающий спазмолитическим действием
FR2579208B1 (fr) * 1985-03-22 1987-05-07 Sanofi Sa Nouveaux derives de le 5-h pyrido (3', 4' : 4,5) pyrrolo (3,2-c) pyridine, leur procede de preparation et leur activite antitumorale
US4940715A (en) * 1988-05-17 1990-07-10 Kissei Pharmaceutical Co., Ltd. 5H-pyrazolo[4,3-A] quinolizin-5-one compounds exhibiting therapeutic activities
CA2030056C (fr) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines et leur utilisation pour la prevention ou le traitement de l'infection par le hiv
HUT74170A (en) * 1993-07-06 1996-11-28 Pfizer Bicyclic tetrahydro pyrazolopyridines
CA2143143A1 (fr) * 1994-03-08 1995-09-09 Toshihiko Tanaka Derives de la 3-phenylpyrrolidine

Also Published As

Publication number Publication date
DK0837860T3 (da) 2002-05-27
AU694871B2 (en) 1998-07-30
CN1061044C (zh) 2001-01-24
IS1913B (is) 2004-02-03
IL118485A (en) 2000-02-17
NO306256B1 (no) 1999-10-11
DE69525978D1 (de) 2002-04-25
CZ287251B6 (en) 2000-10-11
TW460469B (en) 2001-10-21
SK282167B6 (sk) 2001-11-06
SI9600186A (en) 1997-04-30
ATE214700T1 (de) 2002-04-15
FI114097B (fi) 2004-08-13
CO4700460A1 (es) 1998-12-29
EP0837860B1 (fr) 2002-03-20
RU2161158C2 (ru) 2000-12-27
JPH10510242A (ja) 1998-10-06
LV11620B (en) 1997-04-20
OA10458A (en) 2002-03-27
PL314459A1 (en) 1996-12-09
YU49346B (sh) 2005-07-19
AP609A (en) 1997-09-03
HRP960268A2 (en) 1997-08-31
AR002745A1 (es) 1998-04-29
AU5477396A (en) 1996-12-19
IL118485A0 (en) 1996-09-12
YU34696A (sh) 1999-07-28
BG100640A (bg) 1997-03-31
SG54341A1 (en) 1998-11-16
KR100225719B1 (en) 1999-10-15
FI974434A0 (fi) 1997-12-05
WO1996039408A1 (fr) 1996-12-12
CZ162696A3 (en) 1997-01-15
BG62568B1 (bg) 2000-02-29
NZ286734A (en) 1998-02-26
BR9602627A (pt) 1998-09-01
AP9600806A0 (en) 1996-07-31
US6004974A (en) 1999-12-21
HUP9601541A3 (en) 1997-05-28
TR199600482A1 (tr) 1997-03-21
SK71896A3 (en) 1997-05-07
HU9601541D0 (en) 1996-07-29
PL184195B1 (pl) 2002-09-30
FI974434L (fi) 1997-12-05
JP3107827B2 (ja) 2000-11-13
PT837860E (pt) 2002-07-31
SA96170065B1 (ar) 2005-12-21
CA2223624A1 (fr) 1996-12-12
NO962320L (no) 1996-12-09
CA2223624C (fr) 2001-02-20
DE69525978T2 (de) 2002-12-19
MY116527A (en) 2004-02-28
HRP960268B1 (en) 2002-12-31
KR970003440A (ko) 1997-01-28
DZ2044A1 (fr) 2002-07-21
ES2172583T3 (es) 2002-10-01
HUP9601541A2 (en) 1997-02-28
KR100191972B1 (ko) 1999-06-15
MX9709897A (es) 1998-03-31
LV11620A (lv) 1996-12-20
EP0837860A1 (fr) 1998-04-29
CN1142499A (zh) 1997-02-12
NO962320D0 (no) 1996-06-05
TNSN96083A1 (fr) 2005-03-15
IS4350A (is) 1996-12-07
RO115881B1 (ro) 2000-07-28

Similar Documents

Publication Publication Date Title
MA23893A1 (fr) 5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant
MA19048A1 (fr) Imidazo [1,2-a] pyridine,procedes pour leur preparation et composition pharmaceutiques les contenant .
DZ2321A1 (fr) Aralkyl-et arylkylidène-lactames et -imides hétér ocycliques procédés pour leur préparation et compositions pharamceutiques les contenant.
FR2610634B1 (fr) Nouveaux polyimide-siloxanes, procedes pour leur preparatio n et articles les contenant
FR2647789B1 (fr) Composes photochromiques de type indolino-spiro-oxazine, leur procede de preparation, compositions et articles photochromiques contenant de tels composes
MA22521A1 (fr) Compositions anti- transpirantes en batonnets-gels contenant un derive de la 2-oxazolidinone, et procede pour leur preparation
MA23880A1 (fr) Amines bicycliques utiles comme insecticides, procede pour leur preparation et compositions les contenant
MA26653A1 (fr) Pyrrolo [2,3- d] pyrimidines nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant
IL89347A0 (en) Thieno(3,2-b)pyridines,process for their preparation and pharmaceutical compositions containing them
ZA899434B (en) 9-a2a-3-(oxa-thia)-biocyclo 3,2,1 nonane derivatives,process intermediates for their preparation and pharmaceutical compositions containing them
HU202520B (en) Process for producing 6,11-dihydro-11-(4-piperidinylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridines and pharmaceutical compositions comprising same
FR2705095B1 (fr) Nouveaux indoles substitués, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
BE894927A (fr) Derives de l'ergoline, procede pour leur preparation et medicaments les contenant
FR2512442B1 (fr) Derives de cyclopentadiene, procede de leur preparation, composition les contenant et procede de fabrication d'articles moules les utilisant
FR2565981B1 (fr) Nouveaux derives de thieno (2,3-b) pyrrole, leur procede de preparation et les compositions pharmaceutiques les renfermant
MA21588A1 (fr) Derives d'ether de n-pheryl pyrazole-4-yle, compositions les contenant et leur procede de preparation.
FR2562071B1 (fr) Triazolo(4,3-b)pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant
OA07341A (fr) Nouveaux oximéthers, procédé pour leur préparation, agents contenant les nouveaux oximéthers et leur application.
MA23651A1 (fr) Spirostanylglycosides cristallins, procede pour leur preparation et compositions les contenant
FR2530637B1 (fr) Derives n-carbamoyl d'isothiazolo-(5,4b)pyridine one-3, leur procede de preparation et compositions anti-acneiques les contenant
HUP9602054A2 (en) Benzofuro- and benzothieno[3,2-b]pyridine derivatives, pharmaceutical compositions containing them, and process for the preparation thereof
HUT70504A (en) Thieno[3,4-c]pyrrol derivatives, pharmaceutical compositions containing them and process for preparing them
FR2526425B1 (fr) Derives de cycloalcanes, procede pour leur preparation et compositions les contenant
FR2573762B1 (fr) Derives 4-hydroxyphenylthioalkyliques substitues, compositions les contenant et leur procede d'emploi
FR2647451B1 (fr) Derives d'imidazo(1,2-a)pyridine, procede de preparation, compositions pharmaceutiques les contenant