MA25758A1 - Inhibiteurs de protease. - Google Patents

Inhibiteurs de protease.

Info

Publication number: MA25758A1
Authority: MA; Morocco
Prior art keywords: protease inhibitors; protease; inhibitors
Prior art date: 2000-06-14

Application number

MA26952A

Other languages

English (en)

Inventor

W Marquis Robert Jr

Ru Yu

F Veber Daniel

D Cummings Maxwell

K Thompson Scott

S Yamashita Dennis

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-14

Filing date

2002-12-13

Publication date

2003-04-01

2002-12-13 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2003-04-01 Publication of MA25758A1 publication Critical patent/MA25758A1/fr

Links

229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
239000000137 peptide hydrolase inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

MA26952A 2000-06-14 2002-12-13 Inhibiteurs de protease. MA25758A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59384500A	2000-06-14	2000-06-14

Publications (1)

Publication Number	Publication Date
MA25758A1 true MA25758A1 (fr)	2003-04-01

Family

ID=24376433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA26952A MA25758A1 (fr)	2000-06-14	2002-12-13	Inhibiteurs de protease.

Country Status (25)

Country	Link
EP (1)	EP1307204A4 (fr)
JP (1)	JP2004503502A (fr)
KR (1)	KR20030008220A (fr)
CN (1)	CN1444481A (fr)
AP (1)	AP2002002671A0 (fr)
AR (1)	AR032622A1 (fr)
AU (1)	AU2001268407A1 (fr)
BG (1)	BG107327A (fr)
BR (1)	BR0111693A (fr)
CA (1)	CA2412353A1 (fr)
CZ (1)	CZ20024086A3 (fr)
EA (1)	EA200300018A1 (fr)
EC (1)	ECSP024388A (fr)
HU (1)	HUP0301231A2 (fr)
IL (1)	IL153421A0 (fr)
MA (1)	MA25758A1 (fr)
MX (1)	MXPA02012442A (fr)
NO (1)	NO20025786L (fr)
NZ (1)	NZ522965A (fr)
OA (1)	OA12288A (fr)
PE (1)	PE20011374A1 (fr)
PL (1)	PL360508A1 (fr)
SK (1)	SK17592002A3 (fr)
WO (1)	WO2001095911A1 (fr)
ZA (1)	ZA200209808B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001034159A1 (fr) *	1999-11-10	2001-05-17	Smithkline Beecham Corporation	Inhibiteurs de protease
EP1231921A4 (fr) *	1999-11-10	2004-06-23	Smithkline Beecham Corp	Inhibiteurs de proteases
CN1635903A (zh) *	2000-11-22	2005-07-06	史密丝克莱恩比彻姆公司	蛋白酶抑制剂
NZ526883A (en)	2001-02-20	2005-11-25	Chugai Pharmaceutical Co Ltd	Azoles as malonyl-coa decarboxylase inhibitors useful as metabolic modulators
US7709510B2 (en)	2001-02-20	2010-05-04	Chugai Seiyaku Kabushiki Kaisha	Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
AU2002342682A1 (en) *	2001-05-17	2002-11-25	Smithkline Beecham Corporation	Protease inhibitors
GB0220187D0 (en) *	2002-08-30	2002-10-09	Novartis Ag	Organic compounds
CA2533749C (fr)	2003-08-01	2012-07-10	Chugai Seiyaku Kabushiki Kaisha	Composes de piperidine utiles en tant qu'inhibiteurs de malonyl-coa decarboxylase
JP4727578B2 (ja)	2003-08-01	2011-07-20	中外製薬株式会社	マロニル−ＣｏＡデカルボキシラーゼ阻害剤として有用な複素環式化合物
EP2208495B1 (fr)	2003-08-01	2011-12-14	Chugai Seiyaku Kabushiki Kaisha	Composes azole a base de cyanoguanidine-utilises comme inhibiteurs de malonyl-coa decarboxylase
EP2240491B1 (fr)	2008-01-09	2015-07-15	Amura Therapeutics Limited	DÉRIVÉS DE TÉTRAHYDROFURO(2,3-b)PYRROL-3-ONE COMME INHIBITEURS DE CYSTÉINE PROTÉINASES
CN103275070A (zh) *	2013-05-10	2013-09-04	郑彪	调节单核细胞增殖的四环化合物及其应用
US9427441B2 (en)	2014-02-19	2016-08-30	Indiana University Research And Technology Corporation	Targeting primary cilia to treat glaucoma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DZ2285A1 (fr) *	1996-08-08	2002-12-25	Smithkline Beecham Corp	Inhibiteurs de protéase de la cystéine.
KR100630986B1 (ko) *	1998-12-23	2006-10-09	스미스클라인 비참 코포레이션	프로테아제 억제제
EP1231921A4 (fr) *	1999-11-10	2004-06-23	Smithkline Beecham Corp	Inhibiteurs de proteases
EP1235577A4 (fr) *	1999-11-10	2003-04-09	Smithkline Beecham Corp	Inhibiteurs de protease
WO2002017924A1 (fr) *	2000-09-01	2002-03-07	Smithkline Beecham Corporation	Procede de traitement
CN1635903A (zh) *	2000-11-22	2005-07-06	史密丝克莱恩比彻姆公司	蛋白酶抑制剂
AU2002342682A1 (en) *	2001-05-17	2002-11-25	Smithkline Beecham Corporation	Protease inhibitors

2001
- 2001-06-14 NZ NZ522965A patent/NZ522965A/en unknown
- 2001-06-14 IL IL15342101A patent/IL153421A0/xx unknown
- 2001-06-14 AR ARP010102840A patent/AR032622A1/es not_active Application Discontinuation
- 2001-06-14 PE PE2001000566A patent/PE20011374A1/es not_active Application Discontinuation
- 2001-06-14 PL PL36050801A patent/PL360508A1/xx not_active Application Discontinuation
- 2001-06-14 AP APAP/P/2002/002671A patent/AP2002002671A0/en unknown
- 2001-06-14 HU HU0301231A patent/HUP0301231A2/hu unknown
- 2001-06-14 JP JP2002510089A patent/JP2004503502A/ja active Pending
- 2001-06-14 BR BR0111693-2A patent/BR0111693A/pt not_active IP Right Cessation
- 2001-06-14 EP EP01946344A patent/EP1307204A4/fr not_active Withdrawn
- 2001-06-14 SK SK1759-2002A patent/SK17592002A3/sk not_active Application Discontinuation
- 2001-06-14 CA CA002412353A patent/CA2412353A1/fr not_active Abandoned
- 2001-06-14 OA OA1200200377A patent/OA12288A/en unknown
- 2001-06-14 AU AU2001268407A patent/AU2001268407A1/en not_active Abandoned
- 2001-06-14 CZ CZ20024086A patent/CZ20024086A3/cs unknown
- 2001-06-14 CN CN01813500A patent/CN1444481A/zh active Pending
- 2001-06-14 MX MXPA02012442A patent/MXPA02012442A/es unknown
- 2001-06-14 WO PCT/US2001/019062 patent/WO2001095911A1/fr not_active Ceased
- 2001-06-14 EA EA200300018A patent/EA200300018A1/ru unknown
- 2001-06-14 KR KR1020027017045A patent/KR20030008220A/ko not_active Withdrawn
2002
- 2002-11-28 BG BG107327A patent/BG107327A/bg unknown
- 2002-12-02 NO NO20025786A patent/NO20025786L/no not_active Application Discontinuation
- 2002-12-03 ZA ZA200209808A patent/ZA200209808B/en unknown
- 2002-12-12 EC EC2002004388A patent/ECSP024388A/es unknown
- 2002-12-13 MA MA26952A patent/MA25758A1/fr unknown

Also Published As

Publication number	Publication date
PE20011374A1 (es)	2002-04-07
SK17592002A3 (sk)	2003-05-02
WO2001095911A1 (fr)	2001-12-20
NO20025786D0 (no)	2002-12-02
CA2412353A1 (fr)	2001-12-20
BR0111693A (pt)	2004-04-06
EP1307204A4 (fr)	2004-06-02
PL360508A1 (en)	2004-09-06
OA12288A (en)	2003-12-12
JP2004503502A (ja)	2004-02-05
EA200300018A1 (ru)	2003-06-26
BG107327A (bg)	2003-07-31
AP2002002671A0 (en)	2002-12-31
NZ522965A (en)	2004-06-25
EP1307204A1 (fr)	2003-05-07
AR032622A1 (es)	2003-11-19
NO20025786L (no)	2003-02-12
MXPA02012442A (es)	2003-04-25
IL153421A0 (en)	2003-07-06
ZA200209808B (en)	2004-07-09
CN1444481A (zh)	2003-09-24
KR20030008220A (ko)	2003-01-24
AU2001268407A1 (en)	2001-12-24
CZ20024086A3 (cs)	2003-05-14
HUP0301231A2 (hu)	2003-08-28
ECSP024388A (es)	2003-02-06

Publication	Publication Date	Title
CY2012007I1 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
MX242679B (es)	2006-12-14	Antranilamidas insecticidas.
FI20000004A0 (fi)	2000-01-03	Flavonoidilääke...
NL1017973A1 (nl)	2001-11-13	Inrichting.
DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
BR0108365B1 (pt)	2010-06-29	refrigerador.
MA26775A1 (fr)	2004-12-20	Inhibiteurs de metalloproteases dihetero substituees.
MA25758A1 (fr)	2003-04-01	Inhibiteurs de protease.
CH695519A5 (de)	2006-06-15	Sperrstromthyristor.
BR0101696B1 (pt)	2008-11-18	refrigerador.
NO20025005L (no)	2002-12-06	Proteaseinhibitorer
DZ2815A1 (fr)	2003-12-01	Inhibiteurs de protéase.
NO20032328D0 (no)	2003-05-22	Proteaseinhibitorer
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
ES1046656Y (es)	2001-06-16	Microplanta de transferencia de residuos solidos urbanos.
ZA200207478B (en)	2003-10-08	Protease inhibitors.
ES1049032Y (es)	2002-03-16	Bitubo.
ES1047010Y (es)	2001-07-16	Portalamparas.
ES1045851Y (es)	2001-04-01	Cubitera.
ES1047305Y (es)	2001-08-16	Embudo anti-rebosamiento.
ES1047836Y (es)	2001-10-01	Hidrobicicleta.
IT1316979B1 (it)	2003-05-13	Grigliatrice.
IT249307Y1 (it)	2003-04-08	Ciabatta.
ITNA20000054V0 (it)	2000-11-21	Bloccatappo.
AR027834A1 (es)	2003-04-16	Mediastinoscopio transhiatal.