MA26816A1 - Derives d'amino-triazolopyridine - Google Patents

Derives d'amino-triazolopyridine

Info

Publication number
MA26816A1
MA26816A1 MA26540A MA26540A MA26816A1 MA 26816 A1 MA26816 A1 MA 26816A1 MA 26540 A MA26540 A MA 26540A MA 26540 A MA26540 A MA 26540A MA 26816 A1 MA26816 A1 MA 26816A1
Authority
MA
Morocco
Prior art keywords
amino
triazolopyridine derivatives
triazolopyridine
derivatives
Prior art date
Application number
MA26540A
Other languages
English (en)
Inventor
Trottmann Gerda Huber
Roland Jakob-Roetne
Matthias Heinrich Nettekoven
Claus Riemer
Walter Hunkeler
Gavin John Kilpatrick
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26816A1 publication Critical patent/MA26816A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA26540A 1999-09-06 2002-03-06 Derives d'amino-triazolopyridine MA26816A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99117578 1999-09-06

Publications (1)

Publication Number Publication Date
MA26816A1 true MA26816A1 (fr) 2004-12-20

Family

ID=8238933

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26540A MA26816A1 (fr) 1999-09-06 2002-03-06 Derives d'amino-triazolopyridine

Country Status (22)

Country Link
US (1) US6355653B1 (fr)
EP (1) EP1214322A2 (fr)
JP (1) JP2003528811A (fr)
KR (1) KR20020027625A (fr)
CN (1) CN1379777A (fr)
AR (1) AR037484A1 (fr)
AU (1) AU7511000A (fr)
BR (1) BR0013792A (fr)
CA (1) CA2383998A1 (fr)
CZ (1) CZ20021220A3 (fr)
HR (1) HRP20020172A2 (fr)
HU (1) HUP0203316A3 (fr)
IL (1) IL148167A0 (fr)
MA (1) MA26816A1 (fr)
MX (1) MXPA02001748A (fr)
NO (1) NO20021077L (fr)
PE (1) PE20010629A1 (fr)
PL (1) PL354240A1 (fr)
TR (1) TR200200579T2 (fr)
WO (1) WO2001017999A2 (fr)
YU (1) YU13502A (fr)
ZA (1) ZA200201055B (fr)

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US6514989B1 (en) * 2001-07-20 2003-02-04 Hoffmann-La Roche Inc. Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives
US6693116B2 (en) 2001-10-08 2004-02-17 Hoffmann-La Roche Inc. Adenosine receptor ligands
CA2462806A1 (fr) 2001-10-08 2003-04-17 F. Hoffmann-La Roche Ag Amide d'acide 8-amino-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylique
IL161573A0 (en) 2001-11-30 2004-09-27 Schering Corp [1,2,4]-TRIAZOLE BICYCLIC ADENOSINE A2a RECEPTOR ANTAGONISTS
HUP0105407A3 (en) * 2001-12-21 2004-04-28 Sanofi Aventis Triazolo[1,5-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
BR0306919A (pt) 2002-01-28 2004-11-09 Kyowa Hakko Kogyo Kk Métodos para reduzir ou suprimir a efetividade adversa da terapia de l-dopa e/ou do agonista da dopamina, e para tratamento moderado de l-dopa, composição para tratamento moderado de l-dopa, método para tratar doença de parkinson e/ou complicações motoras de l-dopa, composição para o tratamento da doença de parkinson, e, métodos para prolongar o tratamento eficaz da doença de parkinson, e para tratar os distúrbios de movimento
EP1560818A1 (fr) * 2002-06-13 2005-08-10 Pfizer Inc. Agents anti-gnrh non peptidiques, compositions pharmaceutiques et procedes d'utilisation
WO2005070927A2 (fr) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a]pyridines
WO2006068954A2 (fr) * 2004-12-21 2006-06-29 Schering Corporation Antagonistes de recepteur a2a de pyrazolo [1,5-a]pyrimidine adenosine
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
CA2657247A1 (fr) * 2006-07-28 2008-01-31 Boehringer Ingelheim International Gmbh Composes modulant le recepteur cb2
WO2008039645A1 (fr) * 2006-09-25 2008-04-03 Boehringer Ingelheim International Gmbh Composés modulant le recepteur cb2
EP2096923B1 (fr) * 2006-11-27 2014-01-22 H. Lundbeck A/S Dérivés d'hétéroaryl-amides
JP2010511018A (ja) * 2006-12-01 2010-04-08 ガラパゴス・ナムローゼ・フェンノートシャップ 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物
CN101772498A (zh) * 2007-04-10 2010-07-07 H.隆德贝克有限公司 作为p2x7拮抗剂的杂芳基酰胺类似物
WO2009017954A1 (fr) * 2007-08-01 2009-02-05 Phenomix Corporation Inhibiteurs de kinase jak2
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
CA2704684A1 (fr) * 2007-11-07 2009-05-14 Boehringer Ingelheim International Gmbh Composes modulant le recepteur cb2
US20120015988A1 (en) * 2008-05-13 2012-01-19 Boehringer Ingelheim International Gmbh Sulfone Compounds Which Modulate The CB2 Receptor
RU2560153C2 (ru) * 2008-06-20 2015-08-20 Дженентек, Инк. Триазолпиридиновые соединения, ингибирующие jak, и способы
AU2009259867A1 (en) 2008-06-20 2009-12-23 Genentech, Inc. Triazolopyridine JAK inhibitor compounds and methods
CA2730037A1 (fr) * 2008-07-10 2010-01-14 Boehringer Ingelheim International Gmbh Composes sulfones qui modulent le recepteur cb2
TWI453207B (zh) * 2008-09-08 2014-09-21 Signal Pharm Llc 胺基三唑并吡啶,其組合物及使用其之治療方法
KR20110063485A (ko) * 2008-09-25 2011-06-10 베링거 인겔하임 인터내셔날 게엠베하 Cb2 수용체를 선택적으로 조절하는 설포닐 화합물
MY153913A (en) * 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
MX2011012961A (es) 2009-06-05 2012-01-30 Cephalon Inc Preparacion y usos de derivados de 1,2,4-triazolo[1,5a]-piridina.
US8299103B2 (en) 2009-06-15 2012-10-30 Boehringer Ingelheim International Gmbh Compounds which selectively modulate the CB2 receptor
JP5756800B2 (ja) 2009-06-16 2015-07-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Cb2受容体を調節するアゼチジン2−カルボキサミド誘導体
PT2455381E (pt) * 2009-07-17 2014-06-24 Japan Tobacco Inc Composto de triazolopiridina e sua acção como inibidor da prolil-hidroxilase e indutor da produção de eritropoietina
WO2011037795A1 (fr) * 2009-09-22 2011-03-31 Boehringer Ingelheim International Gmbh Composés à modulation sélective du récepteur cb2
WO2011088015A1 (fr) 2010-01-15 2011-07-21 Boehringer Ingelheim International Gmbh Composés qui modulent le récepteur cb2
JP5746228B2 (ja) 2010-03-05 2015-07-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Cb2受容体を選択的に調節するテトラゾール化合物
US8846936B2 (en) 2010-07-22 2014-09-30 Boehringer Ingelheim International Gmbh Sulfonyl compounds which modulate the CB2 receptor
PE20141553A1 (es) * 2011-09-19 2014-10-30 Hoffmann La Roche Compuestos de triazolopiridina como inhibidores de la ped10a
EP2757882B1 (fr) 2011-09-22 2020-11-04 Merck Sharp & Dohme Corp. Composés imidazopyridyliques utilisables en tant qu'inhibiteurs de l'aldostérone synthase
EP2757883B1 (fr) 2011-09-22 2021-01-13 Merck Sharp & Dohme Corp. Composés triazolopyridyle à utiliser en tant qu'inhibiteurs de l'aldostérone synthase
EP2803668A1 (fr) 2013-05-17 2014-11-19 Boehringer Ingelheim International Gmbh Nouveau (cyano-dimethyl-methyl)-isoxazoles et - [1,3,4] thiadiazoles
BR112018068681A2 (pt) 2016-03-16 2019-01-15 Bayer Cropscience Ag derivados de n-(cianobenzil)-6-(ciclopropil-carbonilamino)-4-(fenil)-piridina-2-carboxamida e compostos relacionados como pesticidas e agentes de proteção de plantas
CN106543175B (zh) * 2016-10-28 2018-06-01 上海大学 三芳基[1,2,4]三氮唑[1,5-a]吡啶衍生物及其制备方法
RU2764655C2 (ru) * 2017-03-16 2022-01-19 Цзянсу Хэнжуй Медицин Ко., Лтд. ПРОИЗВОДНОЕ ГЕТЕРОАРИЛ[4,3-с]ПИРИМИДИН-5-АМИНА, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО МЕДИЦИНСКИЕ ПРИМЕНЕНИЯ
US20190292188A1 (en) 2018-02-27 2019-09-26 Incyte Corporation Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
MA52940A (fr) 2018-05-18 2021-04-28 Incyte Corp Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
CN113166153B (zh) 2018-07-05 2024-11-01 因赛特公司 作为a2a/a2b抑制剂的稠合吡嗪衍生物
WO2020054712A1 (fr) * 2018-09-12 2020-03-19 日本化薬株式会社 Agent de lutte contre les organismes nuisibles
KR20210116488A (ko) 2018-12-20 2021-09-27 인사이트 코포레이션 액티빈 수용체-유사 키나제-2의 억제제로서의 이미다조피리다진 및 이미다조피리딘 화합물
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
CN115867553B (zh) * 2021-01-09 2026-03-06 巴格沃克斯研究有限公司 作为腺苷2A受体和腺苷2B受体拮抗剂的二氨基吡唑[1, 5-a]并嘧啶-6-腈化合物
CN116082335B (zh) * 2023-01-16 2026-02-24 上海凌凯科技股份有限公司 一种二芳基醚化合物的制备方法

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AU2639299A (en) 1998-02-24 1999-09-15 Kyowa Hakko Kogyo Co. Ltd. Remedies/preventives for parkinson's disease

Also Published As

Publication number Publication date
CA2383998A1 (fr) 2001-03-15
IL148167A0 (en) 2002-09-12
HUP0203316A3 (en) 2004-07-28
AR037484A1 (es) 2004-11-17
BR0013792A (pt) 2002-05-14
WO2001017999A2 (fr) 2001-03-15
US6355653B1 (en) 2002-03-12
EP1214322A2 (fr) 2002-06-19
PL354240A1 (en) 2003-12-29
CN1379777A (zh) 2002-11-13
CZ20021220A3 (cs) 2002-10-16
TR200200579T2 (tr) 2002-12-23
NO20021077D0 (no) 2002-03-05
NO20021077L (no) 2002-03-05
PE20010629A1 (es) 2001-05-30
YU13502A (sh) 2004-11-25
HUP0203316A2 (hu) 2003-01-28
HRP20020172A2 (en) 2003-10-31
WO2001017999A3 (fr) 2001-12-06
ZA200201055B (en) 2003-07-30
AU7511000A (en) 2001-04-10
JP2003528811A (ja) 2003-09-30
KR20020027625A (ko) 2002-04-13
MXPA02001748A (es) 2002-08-06

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