MA27056A1 - Derives d'azolylcarbinols d'aryle (ou d'heteroaryle) pour le traitement de l'incontinence d'urine. - Google Patents

Derives d'azolylcarbinols d'aryle (ou d'heteroaryle) pour le traitement de l'incontinence d'urine.

Info

Publication number
MA27056A1
MA27056A1 MA27514A MA27514A MA27056A1 MA 27056 A1 MA27056 A1 MA 27056A1 MA 27514 A MA27514 A MA 27514A MA 27514 A MA27514 A MA 27514A MA 27056 A1 MA27056 A1 MA 27056A1
Authority
MA
Morocco
Prior art keywords
heteroaryl
aryl
derivatives
treatment
azolylcarbinols
Prior art date
Application number
MA27514A
Other languages
English (en)
Inventor
Ramon Marce-Vidal
Blas Andaluz-Mataro
Jordi Frigola-Constansa
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of MA27056A1 publication Critical patent/MA27056A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

DERIVES D'AZOLYLCARBINOLS D'ARYLE (OU D'HETEROARYLE) POUR LE TRAITEMENT DE L'INCONTINENCE D'URINE Dérivés d'azolylcarbinols d'aryle (ou d'hétéroaryle) de la formule générale (I), dans lesquels Ar représente un radical phényle ou un radical thiényle, substitués sur option, R1 représente un atome d'hydrogène ou un groupe alkyle inférieur, R2 représente un dialkylaminoalkyle ou azaheterocyclylalkyle et Het représente un azole non substitué ou substitué sur option par un ou deux substituants, et leurs sels physiologiquement acceptables; sont utiles en tant que médicaments dans la thérapeutique humaine et/ou vétérinaire pour traiter l'incontinence urinaire chez les mammifères, y compris l'homme.
MA27514A 2001-07-06 2004-02-04 Derives d'azolylcarbinols d'aryle (ou d'heteroaryle) pour le traitement de l'incontinence d'urine. MA27056A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101587A ES2180449B1 (es) 2001-07-06 2001-07-06 Derivados de aril (o heteroaril) azolilcarbinoles para el tratamiento de la incontinencia urinaria.

Publications (1)

Publication Number Publication Date
MA27056A1 true MA27056A1 (fr) 2004-12-20

Family

ID=8498326

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27514A MA27056A1 (fr) 2001-07-06 2004-02-04 Derives d'azolylcarbinols d'aryle (ou d'heteroaryle) pour le traitement de l'incontinence d'urine.

Country Status (23)

Country Link
US (2) US20030022925A1 (fr)
EP (1) EP1413305B1 (fr)
JP (1) JP2004521150A (fr)
KR (1) KR20040030788A (fr)
CN (1) CN1543344A (fr)
AR (1) AR034679A1 (fr)
AT (1) ATE327752T1 (fr)
BR (1) BR0211237A (fr)
CA (1) CA2452646A1 (fr)
CY (1) CY1105113T1 (fr)
DE (1) DE60211913T2 (fr)
DK (1) DK1413305T3 (fr)
ES (2) ES2180449B1 (fr)
MA (1) MA27056A1 (fr)
MX (1) MXPA04000065A (fr)
NO (1) NO20040031L (fr)
NZ (1) NZ530817A (fr)
PL (1) PL369062A1 (fr)
PT (1) PT1413305E (fr)
RU (1) RU2308268C2 (fr)
UA (1) UA79238C2 (fr)
WO (1) WO2003004022A1 (fr)
ZA (1) ZA200400780B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142929A1 (en) * 2001-07-06 2004-07-22 Ramon Merce-Vidal Derivatives of aryl (or heteroaryl) azolylcarbinoles for the treatment of urinary incontinence
DE10335566A1 (de) * 2003-07-31 2005-02-24 Grünenthal GmbH Arzneimittel enthaltend Derivate von Aryl( oder Heteroaryl)azolylcarbinolen
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
ES2244326B1 (es) * 2004-04-05 2007-02-16 Laboratorios Del Dr. Esteve, S.A. Combinacion de substancias activas.
EP1584335A3 (fr) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Combinaison de substances actives comprenant un composé carbinol et un opioïde
US20060040924A1 (en) * 2004-06-22 2006-02-23 Laboratorios Dr. Esteve S.A. Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of renal colic
EP1784178A1 (fr) * 2004-07-30 2007-05-16 Laboratorios Del Dr. Esteve, S.A. Aryl (ou heteroaryl) azolylcarbinols
EP1743892A1 (fr) * 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Composés pyrazoline substitués, leur préparation et utilisation comme médicaments
US7897589B2 (en) * 2005-07-15 2011-03-01 Laboratorios Del Dr. Esteve, S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
EP1757587A1 (fr) * 2005-07-15 2007-02-28 Laboratorios Del Dr. Esteve, S.A. Composés de pyrazoline substituée, leur préparation et leur usage comme médicaments
EP1743890A1 (fr) * 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. Dérivés 4,5-dihydro-1H-pyrazole, leur, préparation et utilisation comme médicaments.
US20070021485A1 (en) * 2005-07-22 2007-01-25 Gomis Antonio F Aryl (or heteroaryl) azolylcarbinols
WO2007017127A2 (fr) * 2005-07-29 2007-02-15 Laboratorios Del Dr. Esteve, S.A Forme dosifiee a liberation controlee de composes pyrazole
US8722079B2 (en) 2008-04-18 2014-05-13 Warsaw Orthopedic, Inc. Methods for treating conditions such as dystonia and post-stroke spasticity with clonidine
EP2151234A1 (fr) * 2008-07-28 2010-02-10 Laboratorios Del. Dr. Esteve, S.A. Formulation pharmaceutique comprenant un composé récepteur CB1 dans une solution solide et/ou une dispersion solide
WO2010123999A2 (fr) * 2009-04-21 2010-10-28 Auspex Pharmaceuticals, Inc. Modulateurs 1-méthylpyrazole de la substance p, du peptide apparenté au gène de la calcitonine, des récepteurs adrénergiques et/ou des récepteurs 5-ht

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE891865A (fr) * 1981-01-30 1982-07-22 Sandoz Sa Nouveaux medicaments a base de derives condenses de l'imidazole pour le traitement des troubles urinaires
FR2613720B1 (fr) * 1987-04-10 1990-01-19 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
ES2150353B1 (es) * 1998-04-15 2001-07-01 Esteve Labor Dr Tienilazolilalcoxietanaminas, su preparacion y su aplicacion como medicamentos.
ES2137136B1 (es) * 1998-05-18 2000-07-01 Esteve Labor Dr Empleo de derivados de aril (o heteroaril) azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de la inflamacion neurogenica.
ES2150378B1 (es) * 1998-08-07 2001-07-01 Esteve Labor Dr Empleo de derivados de aril(o heteroaril)azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de los trastornos mediados por un exceso de substancia p.

Also Published As

Publication number Publication date
AR034679A1 (es) 2004-03-03
CY1105113T1 (el) 2010-03-03
US20050131049A1 (en) 2005-06-16
MXPA04000065A (es) 2004-05-21
ES2263792T3 (es) 2006-12-16
WO2003004022A1 (fr) 2003-01-16
ES2180449B1 (es) 2004-01-16
DE60211913D1 (de) 2006-07-06
JP2004521150A (ja) 2004-07-15
CA2452646A1 (fr) 2003-01-16
KR20040030788A (ko) 2004-04-09
EP1413305B1 (fr) 2006-05-31
US20030022925A1 (en) 2003-01-30
ZA200400780B (en) 2005-01-31
ATE327752T1 (de) 2006-06-15
RU2004103475A (ru) 2005-06-10
BR0211237A (pt) 2004-08-10
NZ530817A (en) 2005-07-29
UA79238C2 (en) 2007-06-11
NO20040031L (no) 2004-03-02
PT1413305E (pt) 2006-09-29
ES2180449A1 (es) 2003-02-01
DE60211913T2 (de) 2007-05-24
RU2308268C2 (ru) 2007-10-20
DK1413305T3 (da) 2006-09-18
PL369062A1 (en) 2005-04-18
CN1543344A (zh) 2004-11-03
EP1413305A1 (fr) 2004-04-28

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