MA27457A1 - Formulations de derive d'acide nodulisporique pour un traitement cutane localise contre les parasites. - Google Patents

Formulations de derive d'acide nodulisporique pour un traitement cutane localise contre les parasites.

Info

Publication number
MA27457A1
MA27457A1 MA28236A MA28236A MA27457A1 MA 27457 A1 MA27457 A1 MA 27457A1 MA 28236 A MA28236 A MA 28236A MA 28236 A MA28236 A MA 28236A MA 27457 A1 MA27457 A1 MA 27457A1
Authority
MA
Morocco
Prior art keywords
nodulisporic acid
acid derivative
skin treatment
present
treatment against
Prior art date
Application number
MA28236A
Other languages
English (en)
Inventor
Mark D Soll
Albert Boeckh
Bode Ronus De
Eijk Peter Johannes Sevaas Van
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of MA27457A1 publication Critical patent/MA27457A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention propose, entre autres, des compositions pour dépôt destinées au traitement ou à la prophylaxie d'infestations par des parasites chez des mammifères ou des oiseaux qui comprend : (1) au moins un dérivé de l'acide nodulisporique ; (2) un véhicule vecteur liquide acceptable ; et (3) facultativement, un inhibiteur de cristallisation. L'invention propose également un procédé destiné au traitement d'infestations parasitaires ou à la prophylaxie d'infestation par des parasites chez des mammifères ou des oiseaux qui comprend appliquer de manière topique audit mammifère ou oiseau une quantité efficace d'une composition conformément à la présente invention. En outre, la présente invention se rapporte à un procédé d'amidification destiné à préparer des dérivés amide de l'acide nodulisporique et à l'intermédiaire formé dans ce procédé.
MA28236A 2002-10-02 2005-04-25 Formulations de derive d'acide nodulisporique pour un traitement cutane localise contre les parasites. MA27457A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41562702P 2002-10-02 2002-10-02
US10/618,975 US20040077703A1 (en) 2002-10-02 2003-07-14 Nodulisporic acid derivative spot-on formulations for combating parasites

Publications (1)

Publication Number Publication Date
MA27457A1 true MA27457A1 (fr) 2005-07-01

Family

ID=32073382

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28236A MA27457A1 (fr) 2002-10-02 2005-04-25 Formulations de derive d'acide nodulisporique pour un traitement cutane localise contre les parasites.

Country Status (21)

Country Link
US (1) US20040077703A1 (fr)
EP (1) EP1545211B1 (fr)
JP (1) JP2006502241A (fr)
KR (2) KR20070099668A (fr)
CN (1) CN100496244C (fr)
AP (1) AP2047A (fr)
AU (1) AU2003279002A1 (fr)
BR (1) BR0314531A (fr)
CA (1) CA2500822C (fr)
CO (1) CO5700750A2 (fr)
CR (2) CR7810A (fr)
EA (1) EA009683B1 (fr)
EC (1) ECSP055736A (fr)
ES (1) ES2482101T3 (fr)
GE (1) GEP20084414B (fr)
MA (1) MA27457A1 (fr)
MX (1) MXPA05003581A (fr)
NZ (1) NZ539227A (fr)
UA (1) UA83199C2 (fr)
WO (1) WO2004030457A1 (fr)
ZA (1) ZA200502904B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9416065B2 (en) * 2007-02-12 2016-08-16 Archer Daniels Midland Company Adjuvants and methods of using them
CA2706448C (fr) * 2007-11-26 2016-08-16 Merial Limited Systemes de solvants pour solutions a application cutanee, utilisables dans le cadre de la lutte contre les parasites
EP2875726A1 (fr) 2013-11-13 2015-05-27 Ceva Animal Health Nouvelles applications de compositions vétérinaires dans le traitement contre les parasites
KR101687973B1 (ko) 2015-12-08 2016-12-21 주식회사 씨티씨바이오 마이크로필름 코팅을 이용한 동물 사료용 프리믹스 제조방법
CN111542602B (zh) * 2017-09-29 2025-03-11 维多利亚联结有限公司 多节孢酸(Nodulisporic acid)的异源生物合成
KR102178885B1 (ko) * 2020-01-17 2020-11-13 강현준 카프릴산을 포함하는 안정한 해충 방제제 및 이의 제조방법
WO2026073866A1 (fr) 2024-10-01 2026-04-09 Syngenta Crop Protection Ag Procédés de lutte contre des insectes de la famille des pentatomidae

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753377B1 (fr) * 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US6426333B1 (en) * 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
EP0237482A1 (fr) * 1986-03-06 1987-09-16 Ciba-Geigy Ag Dérivés de la C(29)-carbonyloxy-milbémycine pour la lutte contre les parasites d'espèces végétales ou animales
EP0342710B1 (fr) * 1986-03-25 1993-05-19 Sankyo Company Limited Dérivés du type macrolide, leur préparation et leur utilisation
GB8613914D0 (en) * 1986-06-07 1986-07-09 Coopers Animal Health Liquid formulations
ATE75745T1 (de) * 1986-07-02 1992-05-15 Ciba Geigy Ag Pestizide.
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) * 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
DE3888936T2 (de) * 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
CA2036148A1 (fr) * 1990-06-29 1991-12-30 Hiroki Tomioka Derive de 1-phenylimidazole ainsi que sa production et son utilisation
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
EP0611774B1 (fr) * 1993-02-19 1999-05-26 F. Hoffmann-La Roche Ag Production des amides et des peptides sans racemisation en présence de quantités catalytiques d'un composé N-hydroxylé
GB9315108D0 (en) * 1993-07-21 1993-09-01 Pfizer Ltd Antiparasitic agents
US5399582A (en) * 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
GB9402916D0 (en) * 1994-02-16 1994-04-06 Pfizer Ltd Antiparasitic agents
JPH0827018A (ja) * 1994-07-22 1996-01-30 Sanwa Kagaku Kenkyusho Co Ltd 生理活性ペプチド又は蛋白質を含有する薬剤組成物
AUPM969994A0 (en) * 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US5595998A (en) * 1994-12-15 1997-01-21 Wolin; Ronald L. Pyrazoloquinolines
PL185563B1 (pl) * 1995-03-20 2003-06-30 Merck & Co Inc Pochodne kwasu nodulisporowego oraz zawierające je kompozycje farmaceutyczne
US6221894B1 (en) * 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5595991A (en) * 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
US5962499A (en) * 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
FR2739255B1 (fr) * 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
US6010710A (en) * 1996-03-29 2000-01-04 Merial Direct pour-on skin solution for antiparasitic use in cattle and sheep
IE80657B1 (en) * 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US5885607A (en) * 1996-03-29 1999-03-23 Rhone Merieux N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs
US5834260A (en) * 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
DE69720016T2 (de) * 1996-09-19 2004-01-22 Merck & Co., Inc. Nodulisporinsäurederivate
US6136838A (en) * 1998-03-19 2000-10-24 Merck & Co., Inc. Sulfurpentafluorophenylpyrazoles for controlling ectoparasitic infestations
ATE239701T1 (de) * 1998-03-30 2003-05-15 Lg Chemical Ltd Polyethoxylierte retinamid-derivate und verfahren zu ihrer herstellung
US6399796B2 (en) * 2000-03-17 2002-06-04 Roche Vitamins Inc. Activation of a Diels-Alder reaction of a sterol 5,7-diene
US6399786B1 (en) * 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
US20050234119A1 (en) * 2004-04-16 2005-10-20 Soll Mark D Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals
US20080003282A1 (en) * 2005-04-18 2008-01-03 Soll Mark D Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals

Also Published As

Publication number Publication date
CA2500822A1 (fr) 2004-04-15
US20040077703A1 (en) 2004-04-22
CN1700859A (zh) 2005-11-23
AU2003279002A1 (en) 2004-04-23
GEP20084414B (en) 2008-07-10
EP1545211A1 (fr) 2005-06-29
EA200500579A1 (ru) 2005-08-25
WO2004030457A1 (fr) 2004-04-15
ECSP055736A (es) 2005-09-20
UA83199C2 (ru) 2008-06-25
ES2482101T3 (es) 2014-08-01
HK1072348A1 (en) 2005-08-26
CR10319A (es) 2008-10-21
BR0314531A (pt) 2005-08-09
EA009683B1 (ru) 2008-02-28
CA2500822C (fr) 2013-12-24
ZA200502904B (en) 2005-10-19
MXPA05003581A (es) 2005-06-17
NZ539227A (en) 2007-01-26
JP2006502241A (ja) 2006-01-19
CN100496244C (zh) 2009-06-10
KR20050059235A (ko) 2005-06-17
EP1545211B1 (fr) 2014-04-30
KR20070099668A (ko) 2007-10-09
AP2047A (en) 2009-09-18
AP2005003289A0 (en) 2005-06-30
CR7810A (es) 2005-05-25
CO5700750A2 (es) 2006-11-30

Similar Documents

Publication Publication Date Title
MA65277B1 (fr) Inhibiteurs de l'inflammasome nlrp3
MA27452A1 (fr) Derives d'indole servant d'agonistes beta-2
UY28280A1 (es) 2- hidroxi - 3- diaminoalcanos de benzamida
MA30342B1 (fr) Nouvelles compositions pour des troubles capillaires et procede de preparation de celles-ci
MA30722B1 (fr) Utilisation de derives de l'adenosine en tant qu'agonistes du recepteurs a2a
MA32466B1 (fr) Derives de triazole utiles pour le traitement de maladies
MXPA04000328A (es) Derivados de alfa-hidroxiamida estatina para tratamiento de enfermedad de alzheimer.
TNSN04151A1 (fr) Derives de nicotinamide utiles comme inhibiteurs de pde4
MA27457A1 (fr) Formulations de derive d'acide nodulisporique pour un traitement cutane localise contre les parasites.
DOP2004001052A (es) Inhibidores heterociclil amino de 11-beta-hidroxiesteroide deshidrogenasa tipo 1
MA26997A1 (fr) Derives de 3-(4-amidopyrrole-2-ylmethylidene)-2-indolinone utilisables comme inhibiteurs de proteine-kinases
TN2009000138A1 (fr) Biaryl-ether-urees
BR9904998B1 (pt) derivados de hidroxamida do ácido 5-oxo-pirrolidina-2-carboxìlico e composição farmacêutica.
MA29156B1 (fr) Procede pour lutter contre des maladies provoquees par des champignons sur des legumineuses
MA29170B1 (fr) Derives puriniques agissant comme des agonistes du recepteur a2a
EA200400595A1 (ru) Бензимидазолы, применяемые в качестве ингибиторов протеинкиназы
WO2003027068A3 (fr) Amines substituees pour le traitement de la maladie d'alzheimer
MA35874B1 (fr) Dérivés d'amide cycliques à utiliser en tant qu'inhibiteurs de 11-bêta-hydroxystéroïde déshydrogénase et utilisations de ceux-ci
MA29554B1 (fr) Nouveaux derives d'amide d'acide piperidine carboxylique
EE200100513A (et) Rakkude adhesiooni inhibeerivad põletikuvastased ja immunosupressiivsed ühendid
BR9909620A (pt) Inibidores de metaloproteases de hidroxamato de pirrolidina substituìdo
MA31761B1 (fr) Nouveaux inhibiteurs de seh et leur utilisation
MA27135A1 (fr) Agents antidiabetiques oraux
BR9910494A (pt) Composições sólidas contendo derivados de ácido gama-aminobutìrico e processo para o seu preparo
MA30313B1 (fr) Amines secondaires en tant qu'inhibiteurs de la renine