MA27509A1 - Formulations a liberation prolongee contenant de la lamotrigine - Google Patents
Formulations a liberation prolongee contenant de la lamotrigineInfo
- Publication number
- MA27509A1 MA27509A1 MA28074A MA28074A MA27509A1 MA 27509 A1 MA27509 A1 MA 27509A1 MA 28074 A MA28074 A MA 28074A MA 28074 A MA28074 A MA 28074A MA 27509 A1 MA27509 A1 MA 27509A1
- Authority
- MA
- Morocco
- Prior art keywords
- sustained release
- lamotrigin
- release formulations
- formulations containing
- methods
- Prior art date
Links
- PYZRQGJRPPTADH-UHFFFAOYSA-N lamotrigine Chemical compound NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl PYZRQGJRPPTADH-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960001848 lamotrigine Drugs 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne une formulation à libération prolongée contenant de la lamotrigine, ou un dérivé de la lamotrigine acceptable sur le plan pharmaceutique, ainsi que des méthodes de traitement et des procédés d'utilisation de ces formulations.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0217492A GB0217492D0 (en) | 2002-07-29 | 2002-07-29 | Novel method of treatment |
| GB0217493A GB0217493D0 (en) | 2002-07-29 | 2002-07-29 | Novel methods of treatment |
| GB0313801A GB0313801D0 (en) | 2003-06-13 | 2003-06-13 | Novel methods of treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27509A1 true MA27509A1 (fr) | 2005-09-01 |
Family
ID=31499035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28074A MA27509A1 (fr) | 2002-07-29 | 2005-01-28 | Formulations a liberation prolongee contenant de la lamotrigine |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20050032799A1 (fr) |
| EP (1) | EP1524981B1 (fr) |
| JP (2) | JP4744142B2 (fr) |
| KR (1) | KR100882707B1 (fr) |
| CN (1) | CN100363007C (fr) |
| AR (1) | AR040709A1 (fr) |
| AT (1) | ATE424827T1 (fr) |
| AU (1) | AU2003260336C1 (fr) |
| BR (1) | BRPI0313148B8 (fr) |
| CA (1) | CA2493301A1 (fr) |
| CO (1) | CO5680405A2 (fr) |
| CY (1) | CY1109119T1 (fr) |
| DE (1) | DE60326590D1 (fr) |
| DK (1) | DK1524981T3 (fr) |
| ES (1) | ES2323268T3 (fr) |
| IL (1) | IL166424A (fr) |
| IS (1) | IS2681B (fr) |
| MA (1) | MA27509A1 (fr) |
| MX (1) | MXPA05001243A (fr) |
| MY (1) | MY141049A (fr) |
| NO (1) | NO334221B1 (fr) |
| NZ (1) | NZ537885A (fr) |
| PL (1) | PL213565B1 (fr) |
| PT (1) | PT1524981E (fr) |
| RU (1) | RU2325163C2 (fr) |
| SI (1) | SI1524981T1 (fr) |
| TW (1) | TWI342213B (fr) |
| WO (1) | WO2004012741A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7939102B2 (en) * | 2002-06-07 | 2011-05-10 | Torrent Pharmaceuticals Ltd. | Controlled release formulation of lamotrigine |
| CN100363007C (zh) * | 2002-07-29 | 2008-01-23 | 葛兰素集团有限公司 | 含拉莫三嗪的缓释制剂 |
| US20050169994A1 (en) * | 2003-11-25 | 2005-08-04 | Burke Matthew D. | Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods |
| US20060039975A1 (en) * | 2004-08-20 | 2006-02-23 | Zalman Vilkov | Paroxetine formulations |
| JP5666087B2 (ja) * | 2005-04-06 | 2015-02-12 | アダマス・ファーマシューティカルズ・インコーポレーテッド | Cns関連疾患の治療のための方法及び組成物 |
| WO2008109343A1 (fr) * | 2007-03-01 | 2008-09-12 | Memory Pharmaceuticals Corporation | Procédés de traitement des troubles bipolaires et des déficiences de la mémoire et/ou cognitives associées avec ceux-ci avec du (+)-4-(2-chloro-3-cyanophényl)-1,4-dihydro-2,6-diméthylpyridine-3,5-dicarboxylate d'isopropyle et de 2-méthoxyéthyle |
| US20090022789A1 (en) * | 2007-07-18 | 2009-01-22 | Supernus Pharmaceuticals, Inc. | Enhanced formulations of lamotrigine |
| US8486927B2 (en) * | 2007-11-09 | 2013-07-16 | Thar Pharmaceuticals | Crystalline forms of lamotrigine |
| US20090196924A1 (en) * | 2008-02-04 | 2009-08-06 | Pramod Kharwade | Controlled-release lamotrigine formulations |
| AU2009270768A1 (en) * | 2008-07-18 | 2010-01-21 | Valeant Pharmaceuticals International | Modified release formulation and methods of use |
| US20100323016A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
| US20100323015A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
| AU2010325960C1 (en) | 2009-12-02 | 2015-08-06 | Adamas Pharma, Llc | Amantadine compositions and methods of use |
| WO2011086568A1 (fr) * | 2010-01-13 | 2011-07-21 | Accutest Research Laboratories (I) Pvt. Ltd | Composition à libération contrôlée pour la lamotrigine |
| MX2013008946A (es) * | 2011-02-03 | 2013-10-25 | Lupin Ltd | Composiciones farmaceuticas orales de bepotastina de liberacion controlada. |
| WO2014159275A1 (fr) * | 2013-03-14 | 2014-10-02 | PharmTak, Inc. | Compositions pharmaceutiques à libération contrôlée comprenant de la lamotrigine et procédés de production de celles-ci |
| CN103920134A (zh) * | 2014-05-08 | 2014-07-16 | 崔韡 | 一种治疗儿童眩晕的缓释片及其制备方法 |
| RU2624229C2 (ru) * | 2015-12-21 | 2017-07-03 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Таблетки клозапина с замедленным высвобождением и способ их получения |
| RU2613192C1 (ru) * | 2016-02-18 | 2017-03-15 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Таблетки клозапина с пролонгированным высвобождением |
| US20200046716A1 (en) * | 2017-02-03 | 2020-02-13 | Jubilant Generics Limited | Lamotrigine suspension dosage form |
| CN117860718A (zh) | 2017-08-24 | 2024-04-12 | 阿达玛斯药物有限责任公司 | 金刚烷胺组合物、其制备和使用方法 |
| SG11202003391XA (en) * | 2017-10-27 | 2020-05-28 | Chang Gung Memorial Hospital Linkou | Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof |
| US20190247331A1 (en) | 2018-02-15 | 2019-08-15 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
| US10213393B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság | Composition and method for treating neurological disease |
| US10213394B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
| CN120168449A (zh) * | 2018-04-25 | 2025-06-20 | 纽罗森特里亚股份有限公司 | 苏糖酸镁组合物及其用途 |
| CN114948868B (zh) * | 2021-04-16 | 2023-04-14 | 上海奥科达医药科技股份有限公司 | 一种拉莫三嗪水合物的晶体形式、其制备方法及包含其的组合物 |
| CN116942606A (zh) * | 2022-04-18 | 2023-10-27 | 上海奥科达医药科技股份有限公司 | 拉莫三嗪悬浮液和干混悬剂的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704295A (en) * | 1983-09-19 | 1987-11-03 | Colorcon, Inc. | Enteric film-coating compositions |
| US4556552A (en) * | 1983-09-19 | 1985-12-03 | Colorcon, Inc. | Enteric film-coating compositions |
| JPH0667828B2 (ja) * | 1985-10-09 | 1994-08-31 | 日研化学株式会社 | バルプロ酸ナトリウムの持続性顆粒製剤 |
| US4775536A (en) * | 1986-02-24 | 1988-10-04 | Bristol-Myers Company | Enteric coated tablet and process for making |
| US4816262A (en) * | 1986-08-28 | 1989-03-28 | Universite De Montreal | Controlled release tablet |
| GB8820353D0 (en) * | 1988-08-26 | 1988-09-28 | Staniforth J N | Controlled release tablet |
| IL91398A (en) * | 1988-08-30 | 1994-05-30 | Pfizer | Pharmaceutical delivery device comprising active substance surrounded by asymmetric membrane |
| US5827819A (en) * | 1990-11-01 | 1998-10-27 | Oregon Health Sciences University | Covalent polar lipid conjugates with neurologically active compounds for targeting |
| DK0542364T3 (da) * | 1991-11-13 | 1996-03-11 | Glaxo Canada | Anordning til reguleret frigivelse |
| IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
| US5733575A (en) * | 1994-10-07 | 1998-03-31 | Bpsi Holdings, Inc. | Enteric film coating compositions, method of coating therewith, and coated forms |
| AUPN605795A0 (en) * | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
| CA2264182A1 (fr) * | 1996-08-23 | 1998-02-26 | Algos Pharmaceutical Corporation | Anticonvulsivant renfermant une composition pour traiter la douleur neurogene |
| GB9625795D0 (en) * | 1996-12-12 | 1997-01-29 | Smithkline Beecham Plc | Novel treatment |
| US6046716A (en) * | 1996-12-19 | 2000-04-04 | Colorado Microdisplay, Inc. | Display system having electrode modulation to alter a state of an electro-optic layer |
| CA2216215A1 (fr) * | 1997-04-05 | 1998-10-05 | Isa Odidi | Formulations a liberation prolongee, utilisant des polymeres intelligents, avec caracteristiques de mouillabilite opposees, correspondant a une hydrophobie et a une hydrophilie |
| GB9726987D0 (en) * | 1997-12-22 | 1998-02-18 | Glaxo Group Ltd | Compounds |
| EP1652516A3 (fr) * | 1998-11-02 | 2006-05-17 | ALZA Corporation | Délivrance osmotique contrôlée d'agents actifs |
| GB9930079D0 (en) * | 1999-12-20 | 2000-02-09 | Glaxo Group Ltd | Medicaments |
| GB0024517D0 (en) * | 2000-10-06 | 2000-11-22 | Glaxo Group Ltd | Use of medicaments |
| DE10224170A1 (de) * | 2002-05-31 | 2003-12-11 | Desitin Arzneimittel Gmbh | Pharmazeutische Zusammensetzung mit verzögerter Wirkstofffreisetzung |
| CN100363007C (zh) * | 2002-07-29 | 2008-01-23 | 葛兰素集团有限公司 | 含拉莫三嗪的缓释制剂 |
-
2003
- 2003-07-28 CN CNB038223716A patent/CN100363007C/zh not_active Expired - Lifetime
- 2003-07-28 SI SI200331585T patent/SI1524981T1/sl unknown
- 2003-07-28 KR KR1020057001633A patent/KR100882707B1/ko not_active Expired - Lifetime
- 2003-07-28 BR BRPI0313148A patent/BRPI0313148B8/pt not_active IP Right Cessation
- 2003-07-28 AR AR20030102702A patent/AR040709A1/es not_active Application Discontinuation
- 2003-07-28 DK DK03766343T patent/DK1524981T3/da active
- 2003-07-28 MY MYPI20032831A patent/MY141049A/en unknown
- 2003-07-28 AT AT03766343T patent/ATE424827T1/de active
- 2003-07-28 TW TW092120477A patent/TWI342213B/zh not_active IP Right Cessation
- 2003-07-28 PT PT03766343T patent/PT1524981E/pt unknown
- 2003-07-28 ES ES03766343T patent/ES2323268T3/es not_active Expired - Lifetime
- 2003-07-28 MX MXPA05001243A patent/MXPA05001243A/es active IP Right Grant
- 2003-07-28 AU AU2003260336A patent/AU2003260336C1/en not_active Expired
- 2003-07-28 PL PL374982A patent/PL213565B1/pl unknown
- 2003-07-28 NZ NZ537885A patent/NZ537885A/en not_active IP Right Cessation
- 2003-07-28 WO PCT/EP2003/008368 patent/WO2004012741A1/fr not_active Ceased
- 2003-07-28 JP JP2004525362A patent/JP4744142B2/ja not_active Expired - Lifetime
- 2003-07-28 CA CA002493301A patent/CA2493301A1/fr not_active Withdrawn
- 2003-07-28 EP EP03766343A patent/EP1524981B1/fr not_active Expired - Lifetime
- 2003-07-28 DE DE60326590T patent/DE60326590D1/de not_active Expired - Lifetime
- 2003-07-28 RU RU2005105353/14A patent/RU2325163C2/ru active
- 2003-07-29 US US10/629,177 patent/US20050032799A1/en not_active Abandoned
-
2005
- 2005-01-20 IL IL166424A patent/IL166424A/en unknown
- 2005-01-28 CO CO05007005A patent/CO5680405A2/es not_active Application Discontinuation
- 2005-01-28 MA MA28074A patent/MA27509A1/fr unknown
- 2005-02-22 NO NO20050948A patent/NO334221B1/no not_active IP Right Cessation
- 2005-02-23 IS IS7707A patent/IS2681B/is unknown
-
2009
- 2009-05-29 CY CY20091100580T patent/CY1109119T1/el unknown
-
2010
- 2010-10-15 JP JP2010232745A patent/JP2011057683A/ja active Pending
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