MA27901A1 - Antagonistes du recepteur de l'acetylcholine muscarinique - Google Patents

Antagonistes du recepteur de l'acetylcholine muscarinique

Info

Publication number
MA27901A1
MA27901A1 MA28705A MA28705A MA27901A1 MA 27901 A1 MA27901 A1 MA 27901A1 MA 28705 A MA28705 A MA 28705A MA 28705 A MA28705 A MA 28705A MA 27901 A1 MA27901 A1 MA 27901A1
Authority
MA
Morocco
Prior art keywords
antagonists
muscarinic receptor
acetylcholine muscarinic
acetylcholine
receptor
Prior art date
Application number
MA28705A
Other languages
English (en)
Inventor
Kristen E Belmonte
Jakob Busch-Petersen
Dramane Laine
Michael R Palovich
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MA27901A1 publication Critical patent/MA27901A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Des antagonistes des récepteurs d'acétylcholine muscariniques et des méthodes pour leur utilisation sont proposés.
MA28705A 2003-07-17 2006-01-06 Antagonistes du recepteur de l'acetylcholine muscarinique MA27901A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48798203P 2003-07-17 2003-07-17

Publications (1)

Publication Number Publication Date
MA27901A1 true MA27901A1 (fr) 2006-05-02

Family

ID=34102736

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28705A MA27901A1 (fr) 2003-07-17 2006-01-06 Antagonistes du recepteur de l'acetylcholine muscarinique

Country Status (19)

Country Link
US (1) US7495010B2 (fr)
EP (1) EP1648461A4 (fr)
JP (1) JP2007525478A (fr)
KR (1) KR20060054316A (fr)
CN (1) CN1822839A (fr)
AR (1) AR045914A1 (fr)
AU (1) AU2004259238A1 (fr)
BR (1) BRPI0412537A (fr)
CA (1) CA2532433A1 (fr)
IL (1) IL172912A0 (fr)
IS (1) IS8296A (fr)
MA (1) MA27901A1 (fr)
MX (1) MXPA06000663A (fr)
NO (1) NO20060777L (fr)
PE (1) PE20050250A1 (fr)
RU (1) RU2006104851A (fr)
TW (1) TW200519108A (fr)
WO (1) WO2005009362A2 (fr)
ZA (1) ZA200600167B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005037280A1 (fr) * 2003-10-14 2005-04-28 Glaxo Group Limited Antagonistes du recepteur muscarinique de l'acetylcholine
AU2004281167A1 (en) * 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
PE20050489A1 (es) * 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
WO2005087236A1 (fr) * 2004-03-11 2005-09-22 Glaxo Group Limited Nouveaux antagonistes du recepteur de l'acetylcholine muscarinique m3
EP1725238A4 (fr) * 2004-03-17 2009-04-01 Glaxo Group Ltd Antagonistes du recepteur muscarinique a l'acetylcholine m 3
JP2007529513A (ja) * 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
UY28871A1 (es) * 2004-04-27 2005-11-30 Glaxo Group Ltd Antagonistas del receptor de acetilcolina muscarinico
AU2012202307B2 (en) * 2004-04-27 2015-05-07 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
EP1747219A4 (fr) * 2004-05-13 2010-05-26 Glaxo Group Ltd Domaine de l'invention antagonistes récepteurs d'acétyle choline muscarinique
WO2006055553A2 (fr) * 2004-11-15 2006-05-26 Glaxo Group Limited Nouveaux antagonistes des recepteurs muscariniques de type m3 de l'acetylcholine
EP1937267A4 (fr) * 2005-08-02 2009-08-26 Glaxo Group Ltd Antagonistes des recepteurs de l' acetylcholine muscarinique m3
WO2007022351A2 (fr) * 2005-08-18 2007-02-22 Glaxo Group Limited Antagonistes de recepteurs d'acetylcholine muscarinique
PE20091553A1 (es) 2008-02-06 2009-10-30 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
UY31636A1 (es) 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
AR070562A1 (es) 2008-02-06 2010-04-21 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
WO2010094643A1 (fr) 2009-02-17 2010-08-26 Glaxo Group Limited Dérivés de quinoline et applications associées dans la rhinite et l'urticaire
EP3248970A1 (fr) 2016-05-27 2017-11-29 Zentiva K.S. Les formes du bromure d'uméclidinium
CN118987229A (zh) * 2024-09-10 2024-11-22 北京大学 一种Chrm4特异性拮抗剂在制备治疗肺部2型免疫炎症性疾病的药物中的应用

Family Cites Families (47)

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US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800482A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Olefinic derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800481A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Tertiary alcohol derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
AT298118B (de) 1967-06-08 1972-04-25 Siemens Ag Verfahren zur Umsetzung von Spannungen in digitale Werte und Vorrichtung zur Durchführung des Verfahrens
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EP1613307A4 (fr) 2003-04-07 2008-03-12 Glaxo Group Ltd Antagonistes du recepteur muscarinique m sb 3 /sb de l'acetylcholine
PE20050711A1 (es) 2003-07-17 2005-09-10 Glaxo Group Ltd Compuestos 8-azoniabiciclo[3.2.1] octanos como antagonistas de los receptores muscarinicos de la acetilcolina
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WO2005037280A1 (fr) 2003-10-14 2005-04-28 Glaxo Group Limited Antagonistes du recepteur muscarinique de l'acetylcholine
AU2004281167A1 (en) 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
PE20050489A1 (es) 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
ES2329586T3 (es) 2003-11-21 2009-11-27 Theravance, Inc. Compuestos que tienen actividad agonista del receptor beta2 adrenergico y antagonista del receptor muscarino.
PE20050861A1 (es) 2003-12-03 2005-12-10 Glaxo Group Ltd Derivados de sales ciclicas de amonio cuaternario como antagonistas del receptor muscarinico de acetilcolina
PE20050897A1 (es) 2003-12-03 2005-11-06 Glaxo Group Ltd Nuevos antagonistas del receptor muscarinico m3 de acetilcolina
JP2007529514A (ja) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
JP2007529513A (ja) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
EP1725240A4 (fr) 2004-03-17 2009-03-25 Glaxo Group Ltd Antagonistes du recepteur d'acetylcholine muscarinique
EP1725238A4 (fr) 2004-03-17 2009-04-01 Glaxo Group Ltd Antagonistes du recepteur muscarinique a l'acetylcholine m 3
UY28871A1 (es) 2004-04-27 2005-11-30 Glaxo Group Ltd Antagonistas del receptor de acetilcolina muscarinico
EP1747219A4 (fr) 2004-05-13 2010-05-26 Glaxo Group Ltd Domaine de l'invention antagonistes récepteurs d'acétyle choline muscarinique
EP1749012A4 (fr) 2004-05-28 2009-07-29 Glaxo Group Ltd Antagonistes du recepteur d'acetylcholine muscarinique
WO2006050239A2 (fr) 2004-10-29 2006-05-11 Glaxo Group Limited Antagonistes des recepteurs de l'acetylcholine muscarinique
WO2006055553A2 (fr) 2004-11-15 2006-05-26 Glaxo Group Limited Nouveaux antagonistes des recepteurs muscariniques de type m3 de l'acetylcholine
WO2006055503A2 (fr) 2004-11-15 2006-05-26 Glaxo Group Limited Nouveaux antagonistes du recepteur d'acetylcholine muscarinique m3
PE20061162A1 (es) 2004-12-06 2006-10-14 Smithkline Beecham Corp Compuestos derivados olefinicos de 8-azoniabiciclo[3.2.1]octanos
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WO2006065788A2 (fr) 2004-12-13 2006-06-22 Glaxo Group Limited Nouveaux antagonistes du recepteur muscarinique de l'acetylcholine
WO2006065755A2 (fr) 2004-12-13 2006-06-22 Glaxo Group Limited Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique
WO2007018508A1 (fr) 2005-07-28 2007-02-15 Glaxo Group Limited Nouveaux antagonistes du récepteur muscarinique m3 de l’acétylcholine
WO2007018514A1 (fr) 2005-07-28 2007-02-15 Glaxo Group Limited Nouveaux antagonistes récepteurs d’acétylcholine muscarinique m3
EP1937267A4 (fr) 2005-08-02 2009-08-26 Glaxo Group Ltd Antagonistes des recepteurs de l' acetylcholine muscarinique m3
US20080234315A1 (en) 2005-08-02 2008-09-25 Jakob Busch-Petersen M3 Muscarinic Acetylcholine Receptor Antagonists
WO2007022351A2 (fr) 2005-08-18 2007-02-22 Glaxo Group Limited Antagonistes de recepteurs d'acetylcholine muscarinique

Also Published As

Publication number Publication date
IL172912A0 (en) 2006-06-11
US7495010B2 (en) 2009-02-24
EP1648461A2 (fr) 2006-04-26
CA2532433A1 (fr) 2005-02-03
MXPA06000663A (es) 2006-03-30
RU2006104851A (ru) 2006-06-27
US20060178396A1 (en) 2006-08-10
JP2007525478A (ja) 2007-09-06
CN1822839A (zh) 2006-08-23
WO2005009362A3 (fr) 2005-04-07
KR20060054316A (ko) 2006-05-22
EP1648461A4 (fr) 2009-04-01
AU2004259238A1 (en) 2005-02-03
TW200519108A (en) 2005-06-16
ZA200600167B (en) 2007-01-31
PE20050250A1 (es) 2005-04-08
WO2005009362A2 (fr) 2005-02-03
NO20060777L (no) 2006-04-11
IS8296A (is) 2006-02-13
AR045914A1 (es) 2005-11-16
BRPI0412537A (pt) 2006-09-19

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