MA28495B1 - Derives d'oxadiazolone agonistes de ppar-delta - Google Patents

Derives d'oxadiazolone agonistes de ppar-delta

Info

Publication number
MA28495B1
MA28495B1 MA29354A MA29354A MA28495B1 MA 28495 B1 MA28495 B1 MA 28495B1 MA 29354 A MA29354 A MA 29354A MA 29354 A MA29354 A MA 29354A MA 28495 B1 MA28495 B1 MA 28495B1
Authority
MA
Morocco
Prior art keywords
ppar
agonist
delta
oxadiazolone derivatives
oxadiazolone
Prior art date
Application number
MA29354A
Other languages
English (en)
Inventor
Stefanie Keil
Wolfgang Wendler
Maike Glien
Jochen Goerlitzer
Karen Chandross
Daniel G Mcgarry
Jean Merrill
Patrick Bernardelli
Baptiste Ronan
Corinne Terrier
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA28495B1 publication Critical patent/MA28495B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA29354A 2004-04-01 2006-09-29 Derives d'oxadiazolone agonistes de ppar-delta MA28495B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04007879A EP1586573B1 (fr) 2004-04-01 2004-04-01 Oxadiazolones, procédé pour leur préparation, usage comme agents pharmaceutiques

Publications (1)

Publication Number Publication Date
MA28495B1 true MA28495B1 (fr) 2007-03-01

Family

ID=34924545

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29354A MA28495B1 (fr) 2004-04-01 2006-09-29 Derives d'oxadiazolone agonistes de ppar-delta

Country Status (37)

Country Link
US (3) US20070179191A1 (fr)
EP (3) EP1586573B1 (fr)
JP (1) JP2007530612A (fr)
KR (1) KR20060135857A (fr)
CN (1) CN100582104C (fr)
AR (1) AR050576A1 (fr)
AT (1) ATE435225T1 (fr)
AU (1) AU2005231916A1 (fr)
BR (1) BRPI0509517A (fr)
CA (1) CA2561627A1 (fr)
CR (1) CR8572A (fr)
CY (1) CY1109370T1 (fr)
DE (2) DE602004004631D1 (fr)
DK (1) DK1740583T3 (fr)
DO (1) DOP2005000051A (fr)
EC (1) ECSP066892A (fr)
ES (1) ES2329484T3 (fr)
GT (1) GT200500028A (fr)
HR (1) HRP20090493T1 (fr)
IL (1) IL178056A0 (fr)
MA (1) MA28495B1 (fr)
MY (1) MY142431A (fr)
NO (1) NO20064981L (fr)
PA (1) PA8628701A1 (fr)
PE (1) PE20060323A1 (fr)
PL (1) PL1740583T3 (fr)
PT (1) PT1740583E (fr)
RS (1) RS51186B (fr)
RU (1) RU2374243C2 (fr)
SI (1) SI1740583T1 (fr)
SV (1) SV2006002071A (fr)
TN (1) TNSN06317A1 (fr)
TW (1) TW200602342A (fr)
UA (1) UA84203C2 (fr)
UY (1) UY28837A1 (fr)
WO (1) WO2005097786A1 (fr)
ZA (1) ZA200606870B (fr)

Families Citing this family (16)

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KR20060017929A (ko) * 2004-08-04 2006-02-28 동화약품공업주식회사 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물
BRPI0616465A2 (pt) 2005-09-29 2011-06-21 Sanofi Aventis derivados de fenil-[1,2,4]-oxadiazol-5-ona com grupo fenila, bem como seu uso, composição farmacêutica compreendo os mesmos e processo de preparação da referida composição farmacêutica
NZ566877A (en) 2005-09-29 2010-05-28 Sanofi Aventis Phenyl-1,2,4-oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
NZ566876A (en) 2005-09-29 2010-05-28 Sanofi Aventis Derivatives of 2-aminthiazoles and 2-aminooxazoles, processes for their preparation and their use as pharmaceuticals
KR20090066289A (ko) 2006-09-08 2009-06-23 로드아일랜드하스피틀 알코올 유발성 뇌 질환의 치료, 예방 및 역행
KR101922515B1 (ko) 2006-09-08 2019-02-20 로드아일랜드하스피틀 알코올 유발성 간 질환의 치료, 예방 및 역행
EP1932843A1 (fr) 2006-12-14 2008-06-18 sanofi-aventis Dérivés de sulfonyl-phenyl-2H(1,2,4) oxadiazole-5-one, procédés de préparation de ceux-ci et leur usage sous forme de médicaments
WO2009149819A1 (fr) * 2008-06-09 2009-12-17 Sanofi-Aventis Pyrrolidine sulfonamides annelés avec groupement de tête oxadiazolone, procédés pour leur préparation et leur utilisation comme médicaments
NZ589694A (en) 2008-06-09 2012-05-25 Sanofi Aventis Annelated n-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
EP2288607B1 (fr) * 2008-06-09 2014-09-24 Sanofi Sulfonamides comprenant un hétérocycle et un groupe de tête oxadiazolone, procédés pour les préparer et leur utilisation comme produits pharmaceutiques
ES2617873T3 (es) * 2008-10-10 2017-06-20 Vm Discovery, Inc. Composiciones y métodos para tratar trastornos de alcoholismo, dolor y otras enfermedades
CN102202672A (zh) 2008-10-10 2011-09-28 达拉生物科学公司 使用穗霉素衍生物治疗或预防疼痛的方法
BR112012002311A2 (pt) * 2009-08-05 2016-05-31 Daiichi Sankyo Co Ltd composto, composição farmacêutica, e, uso do composto.
BR112012002293A2 (pt) * 2009-08-05 2016-06-14 Daiichi Sankyo Co Ltd composto, composição farmacêutica, e, uso do composto
WO2015061481A1 (fr) 2013-10-23 2015-04-30 Dara Biosciences, Inc. Méthodes de traitement de tumeurs liquides à l'aide de compositions comprenant des dérivés de spicamycine
WO2021092279A1 (fr) * 2019-11-06 2021-05-14 Board Of Regents, The University Of Texas System Procédés de traitement de maladies de dysmyélinisation/dysmyélinisantes

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Also Published As

Publication number Publication date
EP2083006A1 (fr) 2009-07-29
ATE435225T1 (de) 2009-07-15
US7709509B2 (en) 2010-05-04
PL1740583T3 (pl) 2009-12-31
JP2007530612A (ja) 2007-11-01
BRPI0509517A (pt) 2007-09-11
SV2006002071A (es) 2006-01-30
CY1109370T1 (el) 2014-07-02
PT1740583E (pt) 2009-09-16
EP1740583A1 (fr) 2007-01-10
EP1586573A1 (fr) 2005-10-19
IL178056A0 (en) 2006-12-31
DOP2005000051A (es) 2005-12-15
ECSP066892A (es) 2006-11-24
GT200500028A (es) 2006-06-09
DE602005015204D1 (de) 2009-08-13
KR20060135857A (ko) 2006-12-29
TW200602342A (en) 2006-01-16
US20080255212A1 (en) 2008-10-16
AU2005231916A1 (en) 2005-10-20
TNSN06317A1 (en) 2007-12-03
US20070179191A1 (en) 2007-08-02
UA84203C2 (en) 2008-09-25
PA8628701A1 (es) 2006-11-25
ZA200606870B (en) 2008-04-30
DE602004004631D1 (de) 2007-03-22
NO20064981L (no) 2006-12-28
CN1938300A (zh) 2007-03-28
EP1740583B1 (fr) 2009-07-01
UY28837A1 (es) 2005-10-31
ES2329484T3 (es) 2009-11-26
CN100582104C (zh) 2010-01-20
RU2006138498A (ru) 2008-05-10
PE20060323A1 (es) 2006-03-31
HRP20090493T1 (hr) 2009-10-31
EP1586573B1 (fr) 2007-02-07
RS51186B (sr) 2010-10-31
SI1740583T1 (sl) 2009-12-31
CR8572A (es) 2007-12-04
DK1740583T3 (da) 2009-10-19
WO2005097786A1 (fr) 2005-10-20
MY142431A (en) 2010-11-30
RU2374243C2 (ru) 2009-11-27
CA2561627A1 (fr) 2005-10-20
US20080262052A1 (en) 2008-10-23
AR050576A1 (es) 2006-11-08
HK1100408A1 (zh) 2007-09-21

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