MA29806B1 - Derives de 2-aminothiazoles et 2- aminooxazoles,procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques - Google Patents

Derives de 2-aminothiazoles et 2- aminooxazoles,procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques

Info

Publication number
MA29806B1
MA29806B1 MA30782A MA30782A MA29806B1 MA 29806 B1 MA29806 B1 MA 29806B1 MA 30782 A MA30782 A MA 30782A MA 30782 A MA30782 A MA 30782A MA 29806 B1 MA29806 B1 MA 29806B1
Authority
MA
Morocco
Prior art keywords
disorders
aminothiazoles
derivatives
processes
aminooxazoles
Prior art date
Application number
MA30782A
Other languages
English (en)
Inventor
Stefanie Keil
Matthias Urmann
Maike Glien
Wolfgang Wendler
Karen Chandross
Lan Lee
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MA29806B1 publication Critical patent/MA29806B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D419/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES DÉRIVÉS DE 2-AMINOTHIAZOLES ET 2-AMINOOXAZOLES SOUS TOUTES LEURS FORMES STÉRÉOISOMÈRES, ÉNANTIOMÈRES ET DE MÉLANGES DANS N'IMPORTE QUEL RAPPORT, LES SELS PHYSIOLOGIQUEMENT ACCEPTABLES ET LES FORMES TAUTOMÈRES DE DEUX-CI QUI EXERCENT UNE ACTIVITÉ AGONISTE SUR LES RÉCEPTEURS PPAR$G(D). L'INVENTION DÉCRIT AINSI DES COMPOSÉS REPRÉSENTÉS PAR LA FORMULE (I), DANS LAQUELLE LES RADICAUX SONT TELS QUE DÉFINIS DANS LA DESCRIPTION, AINSI QUE LES SELS PHYSIOLOGIQUEMENT ACCEPTABLES DE CEUX-CI ET LES PROCÉDÉS UTILISÉS POUR LES OBTENIR. CES COMPOSÉS SONT UTILISÉS POUR TRAITER ET/OU PRÉVENIR LES TROUBLES DU MÉTABOLISME DES ACIDES GRAS, LES TROUBLES DE L'UTILISATION DU GLUCOSE, LES TROUBLES IMPLIQUANT L'INSULINORÉSISTANCE ET LA DÉMYÉLINISATION, AINSI QUE D'AUTRES TROUBLES NEURODÉGÉNÉRATIFS DU SYSTÈME NERVEUX CENTRAL ET PÉRIPHÉRIQUE
MA30782A 2005-09-29 2008-03-24 Derives de 2-aminothiazoles et 2- aminooxazoles,procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques MA29806B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05021279 2005-09-29

Publications (1)

Publication Number Publication Date
MA29806B1 true MA29806B1 (fr) 2008-09-01

Family

ID=35764446

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30782A MA29806B1 (fr) 2005-09-29 2008-03-24 Derives de 2-aminothiazoles et 2- aminooxazoles,procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques

Country Status (20)

Country Link
US (1) US7655679B2 (fr)
EP (1) EP1931659B1 (fr)
JP (1) JP2009509987A (fr)
KR (1) KR20080048510A (fr)
CN (1) CN101277953A (fr)
AR (1) AR056542A1 (fr)
AT (1) ATE480536T1 (fr)
AU (1) AU2006299090A1 (fr)
BR (1) BRPI0616477A2 (fr)
CA (1) CA2624100A1 (fr)
DE (1) DE602006016830D1 (fr)
IL (1) IL190230A0 (fr)
MA (1) MA29806B1 (fr)
MY (1) MY148883A (fr)
NO (1) NO20081368L (fr)
NZ (1) NZ566876A (fr)
RU (1) RU2008112199A (fr)
TW (1) TW200732328A (fr)
UY (1) UY29832A1 (fr)
WO (1) WO2007039176A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008327106B2 (en) 2007-11-20 2012-10-04 Sumitomo Chemical Company, Limited Pyridine compound, pesticidal composition and method of controlling pest
US9073881B2 (en) 2011-09-23 2015-07-07 Hoffmann-La Roche Inc. Benzoic acid derivatives
WO2013066839A2 (fr) * 2011-10-31 2013-05-10 Glaxosmithkline Llc Composés et procédés
BR112021024165A2 (pt) * 2019-05-31 2022-04-26 Avolynt Composições e métodos para o tratamento de doenças metabólicas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641796A (en) 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
GB9919413D0 (en) 1999-08-18 1999-10-20 Zeneca Ltd Chemical compounds
AU2003224632A1 (en) * 2002-03-01 2003-09-16 Smithkline Beecham Corporation Hppars activators
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
DE602004004631D1 (de) 2004-04-01 2007-03-22 Sanofi Aventis Deutschland Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika

Also Published As

Publication number Publication date
US20080227834A1 (en) 2008-09-18
BRPI0616477A2 (pt) 2011-06-21
TW200732328A (en) 2007-09-01
EP1931659B1 (fr) 2010-09-08
EP1931659A1 (fr) 2008-06-18
KR20080048510A (ko) 2008-06-02
MY148883A (en) 2013-06-14
CN101277953A (zh) 2008-10-01
UY29832A1 (es) 2007-04-30
NZ566876A (en) 2010-05-28
ATE480536T1 (de) 2010-09-15
DE602006016830D1 (de) 2010-10-21
US7655679B2 (en) 2010-02-02
CA2624100A1 (fr) 2007-04-12
WO2007039176A1 (fr) 2007-04-12
AR056542A1 (es) 2007-10-10
RU2008112199A (ru) 2009-10-10
NO20081368L (no) 2008-06-18
JP2009509987A (ja) 2009-03-12
IL190230A0 (en) 2008-11-03
AU2006299090A1 (en) 2007-04-12

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