MA30981B1 - Derives de sulfonyl-phenyl-2h-(1,2,4)oxadiazol-5-one, procedes de preparation associes et utilisation comme medicaments - Google Patents

Derives de sulfonyl-phenyl-2h-(1,2,4)oxadiazol-5-one, procedes de preparation associes et utilisation comme medicaments

Info

Publication number
MA30981B1
MA30981B1 MA31971A MA31971A MA30981B1 MA 30981 B1 MA30981 B1 MA 30981B1 MA 31971 A MA31971 A MA 31971A MA 31971 A MA31971 A MA 31971A MA 30981 B1 MA30981 B1 MA 30981B1
Authority
MA
Morocco
Prior art keywords
disorders
oxadiazol
sulfonyl
phenyl
derivatives
Prior art date
Application number
MA31971A
Other languages
English (en)
Inventor
Stefanie Keil
Matthias Urmann
Karl Schoenafinger
Wolfgang Wendler
Maike Glien
Hans-Ludwig Schaefer
Eugen Falk
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37998695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA30981(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MA30981B1 publication Critical patent/MA30981B1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/00—Antineoplastic agents
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)

Abstract

L'INVENTION PORTE SUR DES SULFONYL-PHÉNYL-OXADIAZOLONES ET SUR LEURS SELS PHYSIOLOGIQUEMENT ACCEPTABLES ET DÉRIVÉS PHYSIOLOGIQUEMENT FONCTIONNELS MONTRANT UNE ACTIVITÉ AGONISTE DE PPARDELTA OU DE PPARDELTA ET PPARGAMMA. ON DÉCRIT DES COMPOSÉS REPRÉSENTÉS PAR LA FORMULE I, DANS LAQUELLE LES RADICAUX SONT TELS QUE DÉFINIS, ET LEURS SELS PHYSIOLOGIQUEMENT ACCEPTABLES ET DES PROCÉDÉS PERMETTANT DE LES PRÉPARER. LES COMPOSÉS SONT APPROPRIÉS POUR LE TRAITEMENT ET/OU LA PRÉVENTION DE TROUBLES DU MÉTABOLISME DES ACIDES GRAS ET DES TROUBLES DE L'UTILISATION DU GLUCOSE AINSI QUE DE TROUBLES DANS LESQUELS LA RÉSISTANCE À L'INSULINE EST MISE EN JEU ET LA DÉMYÉLINISATION ET AUTRES TROUBLES NEURODÉGÉNÉRATIFS DU SYSTÈME NERVEUX CENTRAL ET PÉRIPHÉRIQUE.
MA31971A 2006-12-14 2009-06-10 Derives de sulfonyl-phenyl-2h-(1,2,4)oxadiazol-5-one, procedes de preparation associes et utilisation comme medicaments MA30981B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06025880A EP1932843A1 (fr) 2006-12-14 2006-12-14 Dérivés de sulfonyl-phenyl-2H(1,2,4) oxadiazole-5-one, procédés de préparation de ceux-ci et leur usage sous forme de médicaments

Publications (1)

Publication Number Publication Date
MA30981B1 true MA30981B1 (fr) 2009-12-01

Family

ID=37998695

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31971A MA30981B1 (fr) 2006-12-14 2009-06-10 Derives de sulfonyl-phenyl-2h-(1,2,4)oxadiazol-5-one, procedes de preparation associes et utilisation comme medicaments

Country Status (24)

Country Link
US (1) US8173674B2 (fr)
EP (2) EP1932843A1 (fr)
JP (1) JP2010512352A (fr)
KR (1) KR20090087922A (fr)
CN (1) CN101558064A (fr)
AR (1) AR064299A1 (fr)
AU (1) AU2007331805A1 (fr)
BR (1) BRPI0720416A2 (fr)
CA (1) CA2672347A1 (fr)
CL (1) CL2007003614A1 (fr)
CO (1) CO6210729A2 (fr)
CR (1) CR10778A (fr)
EC (1) ECSP099409A (fr)
MA (1) MA30981B1 (fr)
MX (1) MX2009005535A (fr)
NO (1) NO20092293L (fr)
PE (1) PE20081404A1 (fr)
RU (1) RU2009126745A (fr)
SV (1) SV2009003293A (fr)
TN (1) TN2009000242A1 (fr)
TW (1) TW200843749A (fr)
UY (1) UY30783A1 (fr)
WO (1) WO2008071311A1 (fr)
ZA (1) ZA200903160B (fr)

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MX2010013264A (es) 2008-06-09 2011-02-25 Sanofi Aventis Sulfonamidas n-heterociclicas aneladas con grupo de cabeza de oxadiazolona, procesos para su preparacion y su uso como sustancias farmaceuticas.
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
EP2582709B1 (fr) 2010-06-18 2018-01-24 Sanofi Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013045413A1 (fr) 2011-09-27 2013-04-04 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
PT4119561T (pt) * 2012-05-25 2024-09-30 Corcept Therapeutics Inc Moduladores de recetores de glucocorticoides de azadecalina fundida com heteroaril-cetona
US12226412B2 (en) 2012-05-25 2025-02-18 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
US8859774B2 (en) 2012-05-25 2014-10-14 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
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EP3165094A1 (fr) 2015-11-03 2017-05-10 Basf Se Oxadiazoles substitués pour lutter contre les champignons phytopathogènes
US20180317490A1 (en) 2015-11-04 2018-11-08 Basf Se Substituted oxadiazoles for combating phytopathogenic fungi
MX2018006235A (es) 2015-11-19 2018-08-01 Basf Se Oxadiazoles sustituidos para combatir hongos fitopatogenos.
JP2018537457A (ja) 2015-11-19 2018-12-20 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 植物病原菌を駆除するための置換オキサジアゾール
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BR112018074569B1 (pt) 2016-06-09 2022-10-04 Basf Se Compostos, uso de n-(2,4-difluorofenil)-4-[5-(trifluorometil)-1,2,4-oxadiazol-3-il] benzamida, composição agroquímica e método para combater fungos nocivos fitopatogênicos
WO2017211650A1 (fr) 2016-06-09 2017-12-14 Basf Se Oxadiazoles substitués pour lutter contre des champignons phytopathogènes
BR112019011293A2 (pt) 2016-12-19 2019-10-08 Basf Se compostos de fórmula i, intermediários, composição agroquímica, uso e método para combater fungos nocivos fitopatogênicos
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CA3055076C (fr) 2017-03-31 2022-02-22 Corcept Therapeutics, Inc. Modulateurs du recepteur de glucocorticoides destines au traitement du cancer du col de l'uterus
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WO2018234139A1 (fr) 2017-06-19 2018-12-27 Basf Se 2-[[5-(trifluorométhyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)acétamides pour lutter contre des champignons phytopathogènes
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