MA30413B1 - Nouvelles compositions pharmaceutiques faiblement dosees contenant du nimesulide, leur preparation et utilisation - Google Patents

Nouvelles compositions pharmaceutiques faiblement dosees contenant du nimesulide, leur preparation et utilisation

Info

Publication number
MA30413B1
MA30413B1 MA31384A MA31384A MA30413B1 MA 30413 B1 MA30413 B1 MA 30413B1 MA 31384 A MA31384 A MA 31384A MA 31384 A MA31384 A MA 31384A MA 30413 B1 MA30413 B1 MA 30413B1
Authority
MA
Morocco
Prior art keywords
preparation
low dose
nimesulide
pharmaceutical compositions
compositions containing
Prior art date
Application number
MA31384A
Other languages
English (en)
Inventor
Rajesh Jain
Kour Chand Jindal
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of MA30413B1 publication Critical patent/MA30413B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une forme pharmaceutique faiblement dosée contenant du nimésulide ou ses sels acceptables pharmaceutiquement, esters, solvates ou hydrates, ainsi que des excipients acceptables pharmaceutiquement. Cette invention a aussi trait à un procédé de préparation de ces formes pharmaceutiques et à leurs méthodes thérapeutiques d'utilisation. Les compositions faiblement dosées (10) sont élaborées pour présenter une certaine biodisponibilité qui est efficace dans le traitement de troubles soignés par des AINS, notamment des troubles qui nécessitent des régimes de traitement à long terme, comme l'arthrite. Ces compositions permettent de diminuer le coût thérapeutique des maladies impliquant des thérapies à long terme, elles sont faciles à produire et débouchent sur la diminution des effets secondaires associés au dosage dans le cadre d'une thérapie au nimésulide.
MA31384A 2006-04-24 2008-11-14 Nouvelles compositions pharmaceutiques faiblement dosees contenant du nimesulide, leur preparation et utilisation MA30413B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1033DE2006 2006-04-24

Publications (1)

Publication Number Publication Date
MA30413B1 true MA30413B1 (fr) 2009-05-04

Family

ID=38624596

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31384A MA30413B1 (fr) 2006-04-24 2008-11-14 Nouvelles compositions pharmaceutiques faiblement dosees contenant du nimesulide, leur preparation et utilisation

Country Status (14)

Country Link
US (1) US20090258947A1 (fr)
EP (1) EP2015740A4 (fr)
JP (1) JP2009534462A (fr)
KR (1) KR20090007608A (fr)
CN (1) CN101431992A (fr)
AU (1) AU2007242405A1 (fr)
BR (1) BRPI0710916A2 (fr)
CA (1) CA2649620A1 (fr)
CR (1) CR10454A (fr)
EA (1) EA200870469A1 (fr)
MA (1) MA30413B1 (fr)
MX (1) MX2008013605A (fr)
RS (1) RS20080497A (fr)
WO (1) WO2007122637A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013108263A1 (fr) 2012-01-18 2013-07-25 Zota Health Care Ltd Formulation pharmaceutique destinée à réduire l'inflammation des os et le frottement articulaire avec une qualité de cartilage améliorée
PL2811833T3 (pl) 2012-02-06 2016-05-31 William L Pridgen Połączenie famcyklowiru i celekoksybu na czynnościowe zespoły somatyczne
CA3042642A1 (fr) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Comprime extrude anti-abus a liberation immediate
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
CA2955229C (fr) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Forme posologique remplie de liquide anti-abus a liberation immediate
CN105434377B (zh) * 2014-08-29 2018-07-03 武汉光谷人福生物医药有限公司 美索舒利片剂及其制备方法
CN105434388B (zh) * 2014-08-29 2018-06-19 武汉光谷人福生物医药有限公司 美索舒利薄膜衣片
CN105435239B (zh) * 2014-08-29 2019-04-26 武汉光谷人福生物医药有限公司 美索舒利薄膜衣片及其制备方法
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
RU2593777C1 (ru) * 2015-04-20 2016-08-10 Общество с ограниченной ответственностью "Трейдсервис" Гелевая форма нимесулида, обладающая противовоспалительным и анальгетическим действием
CN108653225B (zh) * 2018-08-15 2021-01-08 湖北舒邦药业有限公司 一种尼美舒利制剂及其制备方法
CN118773142A (zh) * 2024-05-23 2024-10-15 江南大学 一株分泌尼美舒利单克隆抗体的杂交瘤细胞株及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2023552A6 (es) * 1990-05-22 1992-01-16 Leetrim Limited Procedimiento para la preparacion de compuestos de inclusion de nimesulida con ciclodextrina.
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
IN186315B (fr) * 1996-12-12 2001-08-04 Panacea Biotec Ltd
CN1277550A (zh) * 1997-09-11 2000-12-20 尼科梅德丹麦有限公司 非甾体抗炎药物(NSAIDs)的改进释放的复合型组合物
JPH1192355A (ja) * 1997-09-17 1999-04-06 Shiseido Co Ltd 皮膚外用剤
IN190018B (fr) * 1999-09-28 2003-05-31 Panacea Biotec Ltd
CZ20021076A3 (cs) * 1999-09-28 2002-08-14 Panacea Biotec Limited Prostředky s kontrolovaným uvolňováním obsahující nimesulid
NZ524104A (en) * 2000-09-08 2004-12-24 Pharmacia Italia S Exemestane as chemopreventing agent
AU2003237988A1 (en) * 2002-06-13 2003-12-31 Mount Sinai School Of Medicine Of New York University Inhibiting progressive cognitive impairment
AU2006271150A1 (en) * 2005-07-20 2007-01-25 Panacea Biotec Ltd. Novel pharmaceutical modified release dosage form cyclooxygenase enzyme inhibitor

Also Published As

Publication number Publication date
RS20080497A (sr) 2009-05-06
MX2008013605A (es) 2008-10-30
CN101431992A (zh) 2009-05-13
WO2007122637A1 (fr) 2007-11-01
CR10454A (es) 2009-01-12
CA2649620A1 (fr) 2007-11-01
EP2015740A4 (fr) 2009-11-11
BRPI0710916A2 (pt) 2011-08-23
JP2009534462A (ja) 2009-09-24
US20090258947A1 (en) 2009-10-15
EP2015740A1 (fr) 2009-01-21
AU2007242405A1 (en) 2007-11-01
KR20090007608A (ko) 2009-01-19
EA200870469A1 (ru) 2009-04-28

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