MA31456B1 - Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant - Google Patents

Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant

Info

Publication number
MA31456B1
MA31456B1 MA32435A MA32435A MA31456B1 MA 31456 B1 MA31456 B1 MA 31456B1 MA 32435 A MA32435 A MA 32435A MA 32435 A MA32435 A MA 32435A MA 31456 B1 MA31456 B1 MA 31456B1
Authority
MA
Morocco
Prior art keywords
iron
drugs
complex
derivatives
mixture
Prior art date
Application number
MA32435A
Other languages
Arabic (ar)
English (en)
Inventor
Stefan Reim
Erik Philipp
Felix Funk
Hans-Martin Müller
Peter Geisser
Original Assignee
Vifor Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38287550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA31456(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vifor Int Ag filed Critical Vifor Int Ag
Publication of MA31456B1 publication Critical patent/MA31456B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un complexe de fer et de dérivés d'hydrates de carbone, pouvant être obtenu à partir d'une solution saline de fer(iii) aqueuse et d'une solution aqueuse du produit de l'oxydation, et par dérivatisation consécutive d'une ou plusieurs maltodextrines avec une solution d'hypochlorite aqueuse à un ph alcalin. En cas d'utilisation d'une maltodextrine, l'équivalent dextrose de celle-ci se situe entre 5 et 20, et en cas d'utilisation d'un mélange de plusieurs maltodextrines, l'équivalent dextrose du mélange se situe entre 5 et 20 et l'équivalent dextrose de chaque maltodextrine contenue dans le mélange se situe entre 2 et 40, la dérivatisation consécutive étant réalisée avec un réactif adéquat. L'invention concerne également des procédés de fabrication de ces complexes et des médicaments de prophylaxie et de traitement d'états de carences en fer.
MA32435A 2007-05-29 2009-12-21 Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant MA31456B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07109081A EP1997833A1 (fr) 2007-05-29 2007-05-29 Complexes fer-dérivé d'hydrate de carbone hydrosolubles, leur fabrication et médicaments contenants ces complexes
PCT/EP2008/056276 WO2008145586A1 (fr) 2007-05-29 2008-05-21 Complexes de fer et de dérivés d'hydrates de carbone solubles dans l'eau, leur fabrication et médicaments les contenant

Publications (1)

Publication Number Publication Date
MA31456B1 true MA31456B1 (fr) 2010-06-01

Family

ID=38287550

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32435A MA31456B1 (fr) 2007-05-29 2009-12-21 Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant

Country Status (26)

Country Link
US (1) US8263577B2 (fr)
EP (2) EP1997833A1 (fr)
JP (1) JP5259700B2 (fr)
KR (1) KR101168085B1 (fr)
CN (1) CN101679530B (fr)
AR (1) AR065997A1 (fr)
AU (1) AU2008257683B2 (fr)
BR (1) BRPI0811985B8 (fr)
CA (1) CA2682587C (fr)
CL (1) CL2008001549A1 (fr)
CO (1) CO6241161A2 (fr)
ES (1) ES2547304T3 (fr)
GT (1) GT200900308A (fr)
IL (1) IL201294A (fr)
MA (1) MA31456B1 (fr)
MX (1) MX2009012889A (fr)
MY (1) MY158004A (fr)
NZ (1) NZ581487A (fr)
PE (1) PE20090317A1 (fr)
PL (1) PL2148890T3 (fr)
PT (1) PT2148890E (fr)
RU (1) RU2441881C2 (fr)
TN (1) TN2009000443A1 (fr)
TW (1) TWI372621B (fr)
WO (1) WO2008145586A1 (fr)
ZA (1) ZA200907672B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10249552A1 (de) * 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
PT1973549T (pt) 2006-01-06 2016-10-25 Luitpold Pharm Inc Métodos e composições para administração de ferro
LT3156075T (lt) 2009-03-25 2021-01-11 Pharmacosmos Holding A/S Oligosacharidas ir jo paruošimo būdas
EP2496595A2 (fr) * 2009-11-04 2012-09-12 Symed Labs Limited Procédé de préparation d'un complexe de carboxymaltose ferrique
US9394324B2 (en) 2010-03-23 2016-07-19 Vifor (International) Ag Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias
CN101891832B (zh) * 2010-07-22 2012-01-04 山东农业大学 一种无碱均相生产氧化淀粉方法
WO2012104204A1 (fr) 2011-01-31 2012-08-09 Vifor (International) Ag Composés à base d'un complexe de fer-hydrate de carbone pour la thérapie intraveineuse du paludisme
CA2849926C (fr) * 2011-10-13 2020-07-21 Vidasym, Inc. Composition de fibre de fer, sa preparation et ses utilisations
WO2014138016A1 (fr) 2013-03-08 2014-09-12 Vidasym, Inc. Compositions complexes à constituant ion métallique-fibre fonctionnelle, leur préparation et leurs utilisations
US9370202B2 (en) 2013-03-15 2016-06-21 LG Bionano, LLC Encapsulated metal ion nanoclusters
CN107438626A (zh) * 2015-03-23 2017-12-05 苏文生命科学有限公司 水溶性三价铁碳水化合物复合物的制备
CN105125577B (zh) * 2015-07-29 2018-05-18 南京生命能科技开发有限公司 一种稳定的糖-铁复合物及其制备方法
CN105520955B (zh) * 2015-12-21 2018-05-11 南京生命能科技开发有限公司 一种羧基麦芽糖铁药用组合物及其制备方法
US20210155651A1 (en) * 2018-04-05 2021-05-27 Msn Laboratories Private Limited, R&D Center Process for the preparation of iron (iii) carboxymaltose
CN115368477B (zh) * 2021-05-21 2023-05-02 武汉科福新药有限责任公司 高得率、高含铁量的羧基麦芽糖铁的制备方法
CN115368478B (zh) * 2021-05-21 2023-07-04 武汉科福新药有限责任公司 一种羧基麦芽糖铁的制备方法
CN115322265A (zh) * 2022-08-29 2022-11-11 滨州学院 一种羧基麦芽糖控制性氧化与纯化工艺
WO2026017897A1 (fr) 2024-07-18 2026-01-22 Malian Biologicals Gmbh Supplémentation en fer dans des troubles affectifs et/ou un trouble de stress post-traumatique (ptsd) et/ou des maladies dépendantes de la sérotonine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172860B1 (da) * 1998-03-25 1999-08-16 Pharmacosmos Holding As Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
DE10249552A1 (de) * 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US7964568B2 (en) * 2003-05-30 2011-06-21 Chromaceutical Advanced Technologies, Inc. Synthesis of high molecular weight iron-saccharidic complexes
ITMO20050056A1 (it) * 2005-03-15 2006-09-16 Biofer Spa Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
EP1757299A1 (fr) * 2005-08-25 2007-02-28 Vifor (International) Ag Complexes de fer III pour traiter les manques de fer en patients avec la maladie intestinale inflammatoire

Also Published As

Publication number Publication date
ES2547304T3 (es) 2015-10-05
JP5259700B2 (ja) 2013-08-07
TWI372621B (en) 2012-09-21
WO2008145586A1 (fr) 2008-12-04
AU2008257683B2 (en) 2012-06-21
BRPI0811985B8 (pt) 2021-05-25
CN101679530B (zh) 2012-07-04
NZ581487A (en) 2012-04-27
BRPI0811985A2 (pt) 2014-11-18
EP2148890A1 (fr) 2010-02-03
JP2010528166A (ja) 2010-08-19
GT200900308A (es) 2011-09-06
KR20100010502A (ko) 2010-02-01
RU2009149175A (ru) 2011-07-10
BRPI0811985B1 (pt) 2020-04-07
ZA200907672B (en) 2010-07-28
IL201294A0 (en) 2010-05-31
CA2682587C (fr) 2013-05-14
MX2009012889A (es) 2009-12-10
MY158004A (en) 2016-08-30
RU2441881C2 (ru) 2012-02-10
EP2148890B1 (fr) 2015-08-19
US8263577B2 (en) 2012-09-11
IL201294A (en) 2013-06-27
EP1997833A1 (fr) 2008-12-03
CO6241161A2 (es) 2011-01-20
CA2682587A1 (fr) 2008-12-04
PT2148890E (pt) 2015-10-15
PL2148890T3 (pl) 2016-01-29
CN101679530A (zh) 2010-03-24
PE20090317A1 (es) 2009-04-24
TW200900055A (en) 2009-01-01
CL2008001549A1 (es) 2009-09-25
US20100305063A1 (en) 2010-12-02
HK1140219A1 (en) 2010-10-08
AR065997A1 (es) 2009-07-15
TN2009000443A1 (en) 2011-03-31
KR101168085B1 (ko) 2012-07-24
AU2008257683A1 (en) 2008-12-04

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