MA32453B1 - Manoparticules inograniques, leur preparation et leurs utilisations - Google Patents
Manoparticules inograniques, leur preparation et leurs utilisationsInfo
- Publication number
- MA32453B1 MA32453B1 MA33490A MA33490A MA32453B1 MA 32453 B1 MA32453 B1 MA 32453B1 MA 33490 A MA33490 A MA 33490A MA 33490 A MA33490 A MA 33490A MA 32453 B1 MA32453 B1 MA 32453B1
- Authority
- MA
- Morocco
- Prior art keywords
- particles
- relates
- health
- vivo
- field
- Prior art date
Links
- 239000002245 particle Substances 0.000 abstract 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000010894 electron beam technology Methods 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229910010272 inorganic material Inorganic materials 0.000 abstract 1
- 239000011147 inorganic material Substances 0.000 abstract 1
- 230000005865 ionizing radiation Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La présente invention concerne de nouvelles particules excitables pouvant être utilisées dans le domaine de la santé. Elle concerne plus particulièrement des particules pouvant générer des électrons et/ou un photon à haute énergie lorsqu'elles sont excitées par des rayonnements ionisants tels que le rayons x, les rayons gamma, un isotope radioactif et/ou des faisceaux électroniques. Elle concerne les utilisations de ces particules dans le domaine de la santé, notamment de la santé humaine. Les particules de l'invention sont constituées d'une matière inorganique contenant de l'oxygène, en particulier un oxyde, ladite matière présentant une densité appropriée et pouvant être activée in vitro, ex vivo ou in vivo par excitation externe réglable, en vue de perturber, de modifier ou de détruire des cellules cibles, des tissus ou des organes. L'invention concerne en outre des méthodes de production desdites particules, et des compositions pharmaceutiques ou pour dispositifs médicaux contenant ces particules.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08157686A EP2130553A1 (fr) | 2008-06-05 | 2008-06-05 | Nanoparticules inorganiques de haute densité pour détruire des cellules in-vivo |
| US6020208P | 2008-06-10 | 2008-06-10 | |
| PCT/EP2009/056880 WO2009147214A2 (fr) | 2008-06-05 | 2009-06-04 | Nanoparticules inorganiques, leur préparation et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32453B1 true MA32453B1 (fr) | 2011-07-03 |
Family
ID=39734334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA33490A MA32453B1 (fr) | 2008-06-05 | 2011-01-04 | Manoparticules inograniques, leur preparation et leurs utilisations |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8845507B2 (fr) |
| EP (4) | EP2130553A1 (fr) |
| JP (1) | JP5734181B2 (fr) |
| KR (1) | KR101639281B1 (fr) |
| CN (1) | CN102056628B (fr) |
| AU (1) | AU2009254550B2 (fr) |
| BR (1) | BRPI0913410B1 (fr) |
| CA (1) | CA2727576C (fr) |
| CY (2) | CY1118217T1 (fr) |
| DK (2) | DK2300054T3 (fr) |
| EA (1) | EA023012B1 (fr) |
| ES (2) | ES2602048T3 (fr) |
| HR (2) | HRP20161465T8 (fr) |
| HU (2) | HUE030669T2 (fr) |
| IL (1) | IL209625A (fr) |
| LT (2) | LT3150227T (fr) |
| MA (1) | MA32453B1 (fr) |
| MX (1) | MX2010013322A (fr) |
| NZ (1) | NZ589888A (fr) |
| PL (2) | PL2300054T3 (fr) |
| PT (2) | PT2300054T (fr) |
| SG (1) | SG10201405288WA (fr) |
| SI (2) | SI2300054T1 (fr) |
| TR (1) | TR201819077T4 (fr) |
| WO (1) | WO2009147214A2 (fr) |
| ZA (1) | ZA201100082B (fr) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070164238A1 (en) * | 2003-02-24 | 2007-07-19 | Pomper Mark E | Mobile radiation treatment vehicle and method |
| US8459714B2 (en) | 2006-05-19 | 2013-06-11 | Breya, Llc. | Mobile radiation therapy |
| US8657354B2 (en) | 2006-05-19 | 2014-02-25 | Breya, Llc. | Mobile radiation therapy |
| US9232618B2 (en) | 2007-08-06 | 2016-01-05 | Immunolight, Llc | Up and down conversion systems for production of emitted light from various energy sources including radio frequency, microwave energy and magnetic induction sources for upconversion |
| US9399075B2 (en) | 2008-12-29 | 2016-07-26 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US8728440B2 (en) | 2012-08-23 | 2014-05-20 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
| EP2275137A1 (fr) | 2009-07-10 | 2011-01-19 | Nanobiotix | Nanoparticules métalliques, leur préparation et utilisations |
| CN105931696B (zh) * | 2010-04-23 | 2017-07-07 | 皮瑟莱根特科技有限责任公司 | 纳米晶体的合成、盖帽和分散 |
| JP2014503446A (ja) | 2010-10-27 | 2014-02-13 | ピクセリジェント・テクノロジーズ,エルエルシー | ナノ結晶の合成、キャップ形成および分散 |
| US9359689B2 (en) | 2011-10-26 | 2016-06-07 | Pixelligent Technologies, Llc | Synthesis, capping and dispersion of nanocrystals |
| HK1203353A1 (en) | 2011-12-16 | 2015-10-30 | Nanobiotix | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
| EP2877212A4 (fr) * | 2012-06-14 | 2016-04-27 | Univ Arkansas | Compositions et procédés pour une détection et un traitement non invasifs de cellules hypoxiques in vivo |
| US8821838B2 (en) | 2012-08-23 | 2014-09-02 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| UA116007C2 (uk) * | 2013-01-25 | 2018-01-25 | Нанобіотікс | Композиції неорганічних наночастинок у комбінації з іонізуючим випромінюванням для лікування раку |
| WO2014130429A2 (fr) * | 2013-02-19 | 2014-08-28 | National Health Research Institutes | Nanoagrégats de platine en cage pour produits chimiothérapeutiques anticancéreux |
| UA116380C2 (uk) | 2013-05-30 | 2018-03-12 | Нанобіотікс | Посилення терапевтичної або профілактичної ефективності фармацевтичної сполуки |
| EA201690050A1 (ru) | 2013-06-20 | 2016-05-31 | Нанобиотикс | Композиции и способы для применения в медицинской диагностике |
| CA2928952A1 (fr) * | 2013-12-16 | 2015-06-25 | Genentech, Inc. | Composes peptidomimetiques et conjugues anticorps-medicament de ceux-ci |
| EP2886128A1 (fr) * | 2013-12-20 | 2015-06-24 | Nanobiotix | Compositions pharmaceutiques comportant des nanoparticules, leur préparation et leur utilisation |
| TW201628656A (zh) | 2014-11-25 | 2016-08-16 | 奈諾生技公司 | 醫藥組合物、其製備與用途 |
| JP6836510B2 (ja) | 2014-11-25 | 2021-03-03 | キュラディグム・エスアエスCuradigm Sas | 少なくとも2つの異なるナノ粒子と医薬化合物とを組み合わせた医薬組成物、その調製及び使用 |
| HUE056175T2 (hu) | 2014-11-25 | 2022-01-28 | Curadigm Sas | Gyógyászati készítmények, elõállításuk és alkalmazásaik |
| HK1245086A1 (zh) | 2014-11-25 | 2018-08-24 | Nanobiotix | 处方药物组成及其制备和使用 |
| WO2016083331A1 (fr) | 2014-11-25 | 2016-06-02 | Nanobiotix | Composition pharmaceutique, sa préparation et ses utilisations |
| EP3242670B1 (fr) * | 2015-01-08 | 2020-06-24 | Purdue Research Foundation | Formulations non toxiques de nanoparticules radioluminescentes destinées à être utilisées en tant qu'agents radio-sensibilisants du cancer |
| US11096962B2 (en) * | 2015-05-28 | 2021-08-24 | Nanobiotix | Nanoparticles for use as a therapeutic vaccine |
| US11389536B2 (en) | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
| CN109010828B (zh) * | 2018-10-12 | 2020-10-20 | 中国科学院高能物理研究所 | 一种二硫化钼/二氧化铪的复合纳米材料、其制备方法及用途 |
| CN109616308B (zh) * | 2018-11-07 | 2020-09-04 | 湖北第二师范学院 | 一种球形纳米氧化铱dna提取磁性粉末及其生产方法 |
| CN109771645B (zh) * | 2019-03-07 | 2021-08-24 | 广西师范大学 | 一种二氧化钌复合卵清蛋白纳米材料的制备及其应用 |
| WO2021239730A1 (fr) * | 2020-05-26 | 2021-12-02 | Nanobiotix | Nanoparticules, rayonnement ionisant et leurs combinaisons thérapeutiques innovantes |
| IL302571A (en) * | 2020-11-05 | 2023-07-01 | Nanobiotix | Compositions of nanoparticles for treatment of cancer |
| WO2022117529A1 (fr) * | 2020-12-01 | 2022-06-09 | Nanobiotix | Particules poreuses, à haute teneur en z et exemptes de carbone en tant que radioactivateurs |
| KR20250149955A (ko) | 2022-12-12 | 2025-10-17 | 나노비오띡스 | 방사선증강제로서 사용하기 위한 또는 생물학적 조직 시각화를 위한 신규한 금속 산화물 나노입자 및 이의 조성물 |
| EP4595983A1 (fr) | 2024-02-05 | 2025-08-06 | BXTA Nanotherapy Limited | Nanoparticules fonctionnalisées avec un agent stabilisant et un agent de ciblage |
| WO2026074471A1 (fr) * | 2024-10-02 | 2026-04-09 | Janssen Pharmaceutica Nv | Polythérapies avec des nanoparticules d'oxyde d'hafnium et des anticorps pd-l1 destinés à être utilisés dans le traitement du cancer du poumon non à petites cellules |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6287526A (ja) * | 1985-10-11 | 1987-04-22 | Akira Fujishima | 抗腫瘍剤 |
| WO2000006244A2 (fr) | 1998-07-30 | 2000-02-10 | Hainfeld James F | Particules metalliques de chargement dans des vesicules membranaires cellulaires et particule metallique utilisee pour l'imagerie et la therapie |
| EP1696957A2 (fr) | 2003-12-17 | 2006-09-06 | Philips Intellectual Property & Standards GmbH | Radiotherapie et imagerie medicale au moyen de nanoparticules emettant des rayons ultraviolets |
| FR2869803B1 (fr) | 2004-05-10 | 2006-07-28 | Nanobiotix Sarl | Particules activables, preparation et utilisations |
| US20070092927A1 (en) * | 2005-06-13 | 2007-04-26 | University Of Dayton | Photocatalytic particles with directed and controlled redox activity |
| JP2007075696A (ja) * | 2005-09-13 | 2007-03-29 | Mitsubishi Materials Corp | 多孔質光触媒膜 |
| RU2009104312A (ru) * | 2006-07-10 | 2010-08-20 | Конинклейке Филипс Электроникс Н.В. (Nl) | Наночастицы типа "ядро-оболочка" для терапии и диагностических целей |
| EP1920784A1 (fr) * | 2006-11-13 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Sensibilisateurs de radiation pour la thérapie par rayonnements ionisants et pour l'imagerie |
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2008
- 2008-06-05 EP EP08157686A patent/EP2130553A1/fr not_active Withdrawn
-
2009
- 2009-06-04 SI SI200931555A patent/SI2300054T1/sl unknown
- 2009-06-04 PL PL09757595T patent/PL2300054T3/pl unknown
- 2009-06-04 US US12/994,162 patent/US8845507B2/en active Active
- 2009-06-04 NZ NZ589888A patent/NZ589888A/en unknown
- 2009-06-04 BR BRPI0913410-7A patent/BRPI0913410B1/pt active IP Right Grant
- 2009-06-04 SG SG10201405288WA patent/SG10201405288WA/en unknown
- 2009-06-04 CA CA2727576A patent/CA2727576C/fr active Active
- 2009-06-04 HU HUE09757595A patent/HUE030669T2/en unknown
- 2009-06-04 TR TR2018/19077T patent/TR201819077T4/tr unknown
- 2009-06-04 ES ES09757595.5T patent/ES2602048T3/es active Active
- 2009-06-04 EA EA201071429A patent/EA023012B1/ru unknown
- 2009-06-04 PT PT97575955T patent/PT2300054T/pt unknown
- 2009-06-04 ES ES16187263T patent/ES2702249T3/es active Active
- 2009-06-04 EP EP16187263.5A patent/EP3150227B1/fr active Active
- 2009-06-04 JP JP2011512129A patent/JP5734181B2/ja active Active
- 2009-06-04 PL PL16187263T patent/PL3150227T3/pl unknown
- 2009-06-04 MX MX2010013322A patent/MX2010013322A/es active IP Right Grant
- 2009-06-04 KR KR1020117000259A patent/KR101639281B1/ko active Active
- 2009-06-04 LT LTEP16187263.5T patent/LT3150227T/lt unknown
- 2009-06-04 EP EP09757595.5A patent/EP2300054B1/fr active Active
- 2009-06-04 WO PCT/EP2009/056880 patent/WO2009147214A2/fr not_active Ceased
- 2009-06-04 DK DK09757595.5T patent/DK2300054T3/en active
- 2009-06-04 HU HUE16187263A patent/HUE040247T2/hu unknown
- 2009-06-04 CN CN2009801211030A patent/CN102056628B/zh active Active
- 2009-06-04 HR HRP20161465TT patent/HRP20161465T8/hr unknown
- 2009-06-04 AU AU2009254550A patent/AU2009254550B2/en active Active
- 2009-06-04 PT PT16187263T patent/PT3150227T/pt unknown
- 2009-06-04 DK DK16187263.5T patent/DK3150227T3/en active
- 2009-06-04 SI SI200931905T patent/SI3150227T1/sl unknown
- 2009-06-04 EP EP18203014.8A patent/EP3461502A1/fr active Pending
- 2009-06-04 LT LTEP09757595.5T patent/LT2300054T/lt unknown
-
2010
- 2010-11-29 IL IL209625A patent/IL209625A/en active IP Right Grant
-
2011
- 2011-01-04 MA MA33490A patent/MA32453B1/fr unknown
- 2011-01-04 ZA ZA2011/00082A patent/ZA201100082B/en unknown
-
2016
- 2016-11-01 CY CY20161101109T patent/CY1118217T1/el unknown
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2018
- 2018-11-27 HR HRP20181993TT patent/HRP20181993T1/hr unknown
- 2018-12-19 CY CY181101377T patent/CY1121078T1/el unknown
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