MA33290B1 - Pipéridines substituées - Google Patents

Pipéridines substituées

Info

Publication number
MA33290B1
MA33290B1 MA34375A MA34375A MA33290B1 MA 33290 B1 MA33290 B1 MA 33290B1 MA 34375 A MA34375 A MA 34375A MA 34375 A MA34375 A MA 34375A MA 33290 B1 MA33290 B1 MA 33290B1
Authority
MA
Morocco
Prior art keywords
diseases
substituted piperidines
treating
preventing
piperidines
Prior art date
Application number
MA34375A
Other languages
English (en)
Inventor
Dirk Heimbach
Susanne Roehrig
Grande Yolanda Cancho
Eckhard Bender
Katja Zimmermann
Anja Buchmueller
Christoph Gerdes
Mark Jean Gnoth
Kersten Matthias Gericke
Mario Jeske
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of MA33290B1 publication Critical patent/MA33290B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Non-Alcoholic Beverages (AREA)

Abstract

L'invention concerne de nouvelles pipéridines substituées, des procédés pour les produire, leur utilisation pour traiter et/ou prévenir des maladies, ainsi que leur utilisation pour produire des médicaments pour traiter et/ou prévenir des maladies, en particulier des maladies cardiovasculaires et des maladies tumorales.
MA34375A 2009-05-27 2010-05-19 Pipéridines substituées MA33290B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009022896A DE102009022896A1 (de) 2009-05-27 2009-05-27 Substituierte Piperidine
PCT/EP2010/003059 WO2010136144A1 (fr) 2009-05-27 2010-05-19 Pipéridines substituées

Publications (1)

Publication Number Publication Date
MA33290B1 true MA33290B1 (fr) 2012-05-02

Family

ID=42543057

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34375A MA33290B1 (fr) 2009-05-27 2010-05-19 Pipéridines substituées

Country Status (28)

Country Link
US (2) US20120220563A1 (fr)
EP (1) EP2435427A1 (fr)
JP (1) JP5718320B2 (fr)
KR (1) KR20120044289A (fr)
CN (2) CN102596944B (fr)
AR (1) AR076692A1 (fr)
AU (1) AU2010252345A1 (fr)
BR (1) BRPI1012055A2 (fr)
CA (1) CA2763400A1 (fr)
CL (1) CL2011002965A1 (fr)
CO (1) CO6470823A2 (fr)
CR (1) CR20110628A (fr)
CU (1) CU20110215A7 (fr)
DE (1) DE102009022896A1 (fr)
DO (1) DOP2011000364A (fr)
EA (1) EA201190312A1 (fr)
EC (2) ECSP11011483A (fr)
GT (1) GT201100300A (fr)
IL (1) IL215901A0 (fr)
MA (1) MA33290B1 (fr)
MX (1) MX2011012505A (fr)
PE (1) PE20120934A1 (fr)
SG (1) SG175753A1 (fr)
TN (1) TN2011000595A1 (fr)
TW (1) TW201109326A (fr)
UY (2) UY32638A (fr)
WO (1) WO2010136144A1 (fr)
ZA (1) ZA201108565B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022892A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
AP2014007606A0 (en) 2011-10-07 2014-05-31 Takeda Pharmaceutical 1-Arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases
EP3445762B1 (fr) 2016-04-20 2023-09-13 Bristol-Myers Squibb Company Composes heterocycliques bicyliques substitues
EP3535258B1 (fr) 2016-11-03 2021-11-24 Bristol-Myers Squibb Company Dérivés hétérocycliques bicycliques substitués utiles en tant qu'inhibiteurs de canal romk
HUE056142T2 (hu) 2017-06-01 2022-01-28 Bristol Myers Squibb Co Szubsztituált nitrogéntartalmú vegyületek
WO2023044364A1 (fr) 2021-09-15 2023-03-23 Enko Chem, Inc. Inhibiteurs de protoporphyrinogène oxydase

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767144A (en) * 1994-08-19 1998-06-16 Abbott Laboratories Endothelin antagonists
WO1997036873A1 (fr) 1996-04-03 1997-10-09 Merck & Co., Inc. Piperidines, pyrrolidines et hexahydro-1h-azepines declenchant la liberation de l'hormone de croissance
US6403612B2 (en) * 2000-01-31 2002-06-11 Merck & Co., Inc. Thrombin receptor antagonists
BR0213325A (pt) 2001-10-15 2004-10-13 Janssen Pharmaceutica Nv Derivados de 4-fenil-4-[1h-imidazol-2-il]-piperidina substituìda para a redução de dano isquêmico
EP1480957A1 (fr) * 2002-03-01 2004-12-01 Smithkline Beecham Corporation Activateurs de hppars
US8071624B2 (en) 2004-06-24 2011-12-06 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
UA95769C2 (ru) * 2004-06-24 2011-09-12 Инсайт Корпорейшн N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
WO2006002350A1 (fr) 2004-06-24 2006-01-05 Incyte Corporation Composes amido et leur utilisation en tant que produits pharmaceutiques
CA2571258A1 (fr) 2004-06-24 2006-01-05 Incyte Corporation Composes amido et leur utilisation comme produits pharmaceutiques
AU2005273986A1 (en) 2004-08-10 2006-02-23 Incyte Corporation Amido compounds and their use as pharmaceuticals
JP2007008913A (ja) * 2004-09-17 2007-01-18 Tanabe Seiyaku Co Ltd ピペリジン化合物およびその製法
DE102004045796A1 (de) * 2004-09-22 2006-03-23 Merck Patent Gmbh Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung
DE102004061750A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Heteroaryl-substituierte Pyrazoline
CA2621255A1 (fr) 2005-09-21 2007-04-05 Incyte Corporation Utilisation pharmaceutique de composes amido
AU2007210018A1 (en) 2006-01-31 2007-08-09 Incyte Corporation Amido compounds and their use as pharmaceuticals
US20070213311A1 (en) 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
JP2009535420A (ja) 2006-05-01 2009-10-01 インサイト・コーポレイション １１−βヒドロキシルステロイドデヒドロゲナーゼタイプ１のモジュレーターとしてのテトラ置換ウレア
CN101932577B (zh) * 2007-11-30 2013-07-17 拜耳知识产权有限责任公司 杂芳基取代的哌啶
DE102009014484A1 (de) * 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022897A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine

Also Published As

Publication number Publication date
JP2012528090A (ja) 2012-11-12
DOP2011000364A (es) 2012-02-29
WO2010136144A1 (fr) 2010-12-02
EP2435427A1 (fr) 2012-04-04
MX2011012505A (es) 2011-12-14
ECSP11011483A (es) 2011-12-30
BRPI1012055A2 (pt) 2016-05-17
CN104744452A (zh) 2015-07-01
ZA201108565B (en) 2013-01-30
TN2011000595A1 (en) 2013-05-24
US8084469B2 (en) 2011-12-27
GT201100300A (es) 2013-08-21
CN102596944A (zh) 2012-07-18
US20110021489A1 (en) 2011-01-27
US20120220563A1 (en) 2012-08-30
CL2011002965A1 (es) 2012-07-06
CN102596944B (zh) 2015-08-26
UY32636A (es) 2010-12-31
CA2763400A1 (fr) 2010-12-02
AU2010252345A1 (en) 2011-12-08
IL215901A0 (en) 2012-01-31
CO6470823A2 (es) 2012-06-29
EA201190312A1 (ru) 2012-05-30
SG175753A1 (en) 2011-12-29
ECSP11011482A (es) 2011-12-30
DE102009022896A1 (de) 2010-12-02
TW201109326A (en) 2011-03-16
JP5718320B2 (ja) 2015-05-13
CU20110215A7 (es) 2012-03-15
PE20120934A1 (es) 2012-08-01
UY32638A (es) 2010-10-29
AR076692A1 (es) 2011-06-29
KR20120044289A (ko) 2012-05-07
CR20110628A (es) 2012-03-22

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