BRPI1012055A2 - "piperidinas substituídas" - Google Patents

"piperidinas substituídas"

Info

Publication number
BRPI1012055A2
BRPI1012055A2 BRPI1012055A BRPI1012055A BRPI1012055A2 BR PI1012055 A2 BRPI1012055 A2 BR PI1012055A2 BR PI1012055 A BRPI1012055 A BR PI1012055A BR PI1012055 A BRPI1012055 A BR PI1012055A BR PI1012055 A2 BRPI1012055 A2 BR PI1012055A2
Authority
BR
Brazil
Prior art keywords
substituted piperidines
piperidines
substituted
Prior art date
Application number
BRPI1012055A
Other languages
English (en)
Inventor
Anja Buchmuller
Christoph Gerdes
Dirk Heimbach
Eckhard Bender
Katja Zimmermann
Kersten Matthias Gericke
Mario Jeske
Mark Jean Gnoth
Susanne Röhrig
Yolanda Cancho Grande
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of BRPI1012055A2 publication Critical patent/BRPI1012055A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Non-Alcoholic Beverages (AREA)
BRPI1012055A 2009-05-27 2010-05-19 "piperidinas substituídas" BRPI1012055A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009022896A DE102009022896A1 (de) 2009-05-27 2009-05-27 Substituierte Piperidine
PCT/EP2010/003059 WO2010136144A1 (de) 2009-05-27 2010-05-19 Substituierte piperidine

Publications (1)

Publication Number Publication Date
BRPI1012055A2 true BRPI1012055A2 (pt) 2016-05-17

Family

ID=42543057

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1012055A BRPI1012055A2 (pt) 2009-05-27 2010-05-19 "piperidinas substituídas"

Country Status (28)

Country Link
US (2) US20120220563A1 (pt)
EP (1) EP2435427A1 (pt)
JP (1) JP5718320B2 (pt)
KR (1) KR20120044289A (pt)
CN (2) CN104744452A (pt)
AR (1) AR076692A1 (pt)
AU (1) AU2010252345A1 (pt)
BR (1) BRPI1012055A2 (pt)
CA (1) CA2763400A1 (pt)
CL (1) CL2011002965A1 (pt)
CO (1) CO6470823A2 (pt)
CR (1) CR20110628A (pt)
CU (1) CU20110215A7 (pt)
DE (1) DE102009022896A1 (pt)
DO (1) DOP2011000364A (pt)
EA (1) EA201190312A1 (pt)
EC (2) ECSP11011482A (pt)
GT (1) GT201100300A (pt)
IL (1) IL215901A0 (pt)
MA (1) MA33290B1 (pt)
MX (1) MX2011012505A (pt)
PE (1) PE20120934A1 (pt)
SG (1) SG175753A1 (pt)
TN (1) TN2011000595A1 (pt)
TW (1) TW201109326A (pt)
UY (2) UY32638A (pt)
WO (1) WO2010136144A1 (pt)
ZA (1) ZA201108565B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022892A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
US8648079B2 (en) 2011-10-07 2014-02-11 Takeda Pharmaceutical Company Limited Heterocyclic compounds
EP3445762B1 (en) 2016-04-20 2023-09-13 Bristol-Myers Squibb Company Substituted bicyclic heterocyclic compounds
CN110139862B (zh) 2016-11-03 2024-01-16 百时美施贵宝公司 可用作romk通道抑制剂的经取代的二环杂环衍生物
EP3929194B1 (en) 2017-06-01 2024-04-17 Bristol-Myers Squibb Company Substituted nitrogen containing compounds
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767144A (en) * 1994-08-19 1998-06-16 Abbott Laboratories Endothelin antagonists
AU2722297A (en) 1996-04-03 1997-10-22 Merck & Co., Inc. Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
US6403612B2 (en) * 2000-01-31 2002-06-11 Merck & Co., Inc. Thrombin receptor antagonists
CA2462374C (en) 2001-10-15 2011-01-18 Janssen Pharmaceutica N.V. Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage
JP4383177B2 (ja) * 2002-03-01 2009-12-16 スミスクライン ビーチャム コーポレーション ｈＰＰＡＲ活性化剤
MXPA06014572A (es) 2004-06-24 2007-03-12 Incyte Corp Compuestos amido y su uso como farmaceuticos.
WO2006012226A2 (en) 2004-06-24 2006-02-02 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
US20060009491A1 (en) 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
CN1993128A (zh) * 2004-06-24 2007-07-04 因塞特公司 N－取代的哌啶及它们作为药物的用途
EA200700251A1 (ru) 2004-08-10 2007-08-31 Инсайт Корпорейшн Амидосоединения и их применение в качестве фармацевтических средств
JP2007008913A (ja) * 2004-09-17 2007-01-18 Tanabe Seiyaku Co Ltd ピペリジン化合物およびその製法
DE102004045796A1 (de) * 2004-09-22 2006-03-23 Merck Patent Gmbh Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung
DE102004061750A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Heteroaryl-substituierte Pyrazoline
CA2621255A1 (en) 2005-09-21 2007-04-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
BRPI0707408A2 (pt) 2006-01-31 2011-05-03 Incyte Corp compostos de amido e seu uso como produtos farmacêuticos
WO2007101270A1 (en) 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
JP2009535420A (ja) 2006-05-01 2009-10-01 インサイト・コーポレイション １１−βヒドロキシルステロイドデヒドロゲナーゼタイプ１のモジュレーターとしてのテトラ置換ウレア
JP5450435B2 (ja) * 2007-11-30 2014-03-26 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ヘテロアリールで置換されたピペリジン類
DE102009014484A1 (de) * 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022897A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine

Also Published As

Publication number Publication date
EP2435427A1 (de) 2012-04-04
EA201190312A1 (ru) 2012-05-30
DE102009022896A1 (de) 2010-12-02
CN102596944A (zh) 2012-07-18
JP2012528090A (ja) 2012-11-12
SG175753A1 (en) 2011-12-29
MX2011012505A (es) 2011-12-14
CU20110215A7 (es) 2012-03-15
CR20110628A (es) 2012-03-22
MA33290B1 (fr) 2012-05-02
US20110021489A1 (en) 2011-01-27
ECSP11011482A (es) 2011-12-30
PE20120934A1 (es) 2012-08-01
GT201100300A (es) 2013-08-21
CA2763400A1 (en) 2010-12-02
AR076692A1 (es) 2011-06-29
UY32638A (es) 2010-10-29
CL2011002965A1 (es) 2012-07-06
IL215901A0 (en) 2012-01-31
UY32636A (es) 2010-12-31
US20120220563A1 (en) 2012-08-30
CN104744452A (zh) 2015-07-01
US8084469B2 (en) 2011-12-27
WO2010136144A1 (de) 2010-12-02
CN102596944B (zh) 2015-08-26
TW201109326A (en) 2011-03-16
AU2010252345A1 (en) 2011-12-08
DOP2011000364A (es) 2012-02-29
TN2011000595A1 (en) 2013-05-24
ZA201108565B (en) 2013-01-30
ECSP11011483A (es) 2011-12-30
KR20120044289A (ko) 2012-05-07
CO6470823A2 (es) 2012-06-29
JP5718320B2 (ja) 2015-05-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.