MA34051B1 - Composition vaccinale anti-pneumococcique à conjugué protéine-polysaccharide de valence 15 - Google Patents

Composition vaccinale anti-pneumococcique à conjugué protéine-polysaccharide de valence 15

Info

Publication number
MA34051B1
MA34051B1 MA35187A MA35187A MA34051B1 MA 34051 B1 MA34051 B1 MA 34051B1 MA 35187 A MA35187 A MA 35187A MA 35187 A MA35187 A MA 35187A MA 34051 B1 MA34051 B1 MA 34051B1
Authority
MA
Morocco
Prior art keywords
protein
valence
vaccine composition
polysaccharide conjugate
pneumococcal vaccine
Prior art date
Application number
MA35187A
Other languages
Arabic (ar)
English (en)
Inventor
Michael J Caulfield
Patrick L Ahl
Jeffrey T Blue
Jayme L Cannon
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of MA34051B1 publication Critical patent/MA34051B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention porte sur une composition immunogène multivalente ayant 15 conjugués distincts protéine-polysaccharide. Chaque conjugué comprend un polysaccharide capsulaire préparé à partir d'un sérotype différent de
MA35187A 2010-02-09 2011-02-03 Composition vaccinale anti-pneumococcique à conjugué protéine-polysaccharide de valence 15 MA34051B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30272610P 2010-02-09 2010-02-09
PCT/US2011/023526 WO2011100151A1 (fr) 2010-02-09 2011-02-03 Composition vaccinale anti-pneumococcique à conjugué protéine-polysaccharide de valence 15

Publications (1)

Publication Number Publication Date
MA34051B1 true MA34051B1 (fr) 2013-03-05

Family

ID=44353903

Family Applications (1)

Application Number Title Priority Date Filing Date
MA35187A MA34051B1 (fr) 2010-02-09 2011-02-03 Composition vaccinale anti-pneumococcique à conjugué protéine-polysaccharide de valence 15

Country Status (25)

Country Link
US (2) US8192746B2 (fr)
EP (1) EP2533805A4 (fr)
JP (2) JP2013518891A (fr)
KR (1) KR101538535B1 (fr)
CN (1) CN102858365A (fr)
AR (2) AR080122A1 (fr)
AU (1) AU2011216095B2 (fr)
BR (1) BR112012019757B8 (fr)
CA (1) CA2788680C (fr)
CL (1) CL2012002195A1 (fr)
EC (1) ECSP12012100A (fr)
IL (1) IL221283A0 (fr)
MA (1) MA34051B1 (fr)
MX (1) MX2012009206A (fr)
MY (1) MY159984A (fr)
NZ (1) NZ601711A (fr)
PE (1) PE20121698A1 (fr)
PH (1) PH12012501559A1 (fr)
RU (1) RU2012138368A (fr)
SG (2) SG183199A1 (fr)
TN (1) TN2012000377A1 (fr)
TW (1) TW201136603A (fr)
UA (1) UA106115C2 (fr)
WO (1) WO2011100151A1 (fr)
ZA (1) ZA201205737B (fr)

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Also Published As

Publication number Publication date
CA2788680C (fr) 2014-12-16
IL221283A0 (en) 2012-10-31
PH12012501559A1 (en) 2012-10-22
ZA201205737B (en) 2013-04-24
NZ601711A (en) 2014-03-28
KR20120114345A (ko) 2012-10-16
US20110195086A1 (en) 2011-08-11
CN102858365A (zh) 2013-01-02
MY159984A (en) 2017-02-15
US8192746B2 (en) 2012-06-05
BR112012019757B1 (pt) 2020-11-17
US20120301502A1 (en) 2012-11-29
TN2012000377A1 (en) 2014-01-30
TW201136603A (en) 2011-11-01
AR116043A2 (es) 2021-03-25
WO2011100151A1 (fr) 2011-08-18
UA106115C2 (uk) 2014-07-25
ECSP12012100A (es) 2013-03-28
AU2011216095A1 (en) 2012-08-09
SG183199A1 (en) 2012-09-27
JP2014012720A (ja) 2014-01-23
EP2533805A4 (fr) 2013-08-28
SG10201500350PA (en) 2015-03-30
AU2011216095B2 (en) 2013-07-18
BR112012019757A2 (pt) 2016-05-10
AR080122A1 (es) 2012-03-14
PE20121698A1 (es) 2012-12-11
KR101538535B1 (ko) 2015-07-22
RU2012138368A (ru) 2014-03-20
JP2013518891A (ja) 2013-05-23
EP2533805A1 (fr) 2012-12-19
MX2012009206A (es) 2012-08-23
CL2012002195A1 (es) 2012-11-30
CA2788680A1 (fr) 2011-08-18
BR112012019757B8 (pt) 2023-04-25

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