MA34527B1 - Anticorps contre la metalloproteinase de matrice 9 - Google Patents
Anticorps contre la metalloproteinase de matrice 9Info
- Publication number
- MA34527B1 MA34527B1 MA35741A MA35741A MA34527B1 MA 34527 B1 MA34527 B1 MA 34527B1 MA 35741 A MA35741 A MA 35741A MA 35741 A MA35741 A MA 35741A MA 34527 B1 MA34527 B1 MA 34527B1
- Authority
- MA
- Morocco
- Prior art keywords
- matrix
- antibodies against
- mmp9
- functional fragment
- metalloproteinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La présente invention concerne des compositions et des procédés d'utilisation mettant en Suvre des protéines de liaison, par exemple, des anticorps et des fragments de liaison d'antigène de ceux-ci, qui se lient à la protéine de métalloprotéinase de matrice 9 (MMP9) (MMP9 est également appelée gélatinase B), les protéines de liaison comprenant une chaîne lourde d'immunoglobuline (Ig) (ou un fragment fonctionnel de celle-ci) et une chaîne légère de Ig (ou un fragment fonctionnel de celle-ci).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37788610P | 2010-08-27 | 2010-08-27 | |
| PCT/US2011/049448 WO2012027721A2 (fr) | 2010-08-27 | 2011-08-26 | Anticorps contre la métalloprotéinase de matrice 9 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34527B1 true MA34527B1 (fr) | 2013-09-02 |
Family
ID=45724100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35741A MA34527B1 (fr) | 2010-08-27 | 2011-08-26 | Anticorps contre la metalloproteinase de matrice 9 |
Country Status (29)
| Country | Link |
|---|---|
| US (7) | US8377443B2 (fr) |
| EP (1) | EP2608809B1 (fr) |
| JP (3) | JP5878538B2 (fr) |
| KR (4) | KR101881724B1 (fr) |
| CN (2) | CN104530238B (fr) |
| AP (2) | AP3948A (fr) |
| AU (1) | AU2011293125B2 (fr) |
| BR (1) | BR112013004579B1 (fr) |
| CA (1) | CA2808418C (fr) |
| CL (1) | CL2013000535A1 (fr) |
| CO (1) | CO6680656A2 (fr) |
| CR (1) | CR20130132A (fr) |
| EA (1) | EA031729B1 (fr) |
| EC (1) | ECSP13012525A (fr) |
| ES (1) | ES2739505T3 (fr) |
| IL (2) | IL224614A (fr) |
| MA (1) | MA34527B1 (fr) |
| MX (1) | MX342413B (fr) |
| NZ (2) | NZ701444A (fr) |
| PE (1) | PE20131376A1 (fr) |
| PH (2) | PH12013500347A1 (fr) |
| PL (1) | PL2608809T3 (fr) |
| PT (1) | PT2608809T (fr) |
| SG (2) | SG10201506703VA (fr) |
| SI (1) | SI2608809T1 (fr) |
| TR (1) | TR201910348T4 (fr) |
| UA (1) | UA109908C2 (fr) |
| WO (1) | WO2012027721A2 (fr) |
| ZA (2) | ZA201301338B (fr) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2608809B1 (fr) * | 2010-08-27 | 2019-05-22 | Gilead Biologics, Inc. | Anticorps contre la métalloprotéinase de matrice 9 |
| EP3604339B1 (fr) | 2011-01-14 | 2021-03-10 | The Regents Of The University Of California | Anticorps thérapeutiques contre la protéine ror-1 et leurs procédés d'utilisation |
| WO2013130078A1 (fr) * | 2012-02-29 | 2013-09-06 | Gilead Biologics, Inc. | Anticorps dirigés contre la métalloprotéinase 9 de la matrice |
| HK1204926A1 (en) | 2012-02-29 | 2015-12-11 | 吉联亚生物科技有限公司 | Antibodies to matrix metalloproteinase 9 |
| MX2015014053A (es) * | 2013-04-05 | 2016-04-07 | Claudia Zylberberg | Metaloproteinasas de matriz y sus usos. |
| WO2015081127A2 (fr) | 2013-11-26 | 2015-06-04 | Gilead Sciences, Inc. | Therapies pour le traitement de troubles myeloproliferatifs |
| CA2937320A1 (fr) | 2014-01-20 | 2015-07-23 | Gilead Sciences, Inc. | Therapies pour le traitement de cancers |
| EP2985296A1 (fr) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Anticorps spécifiques de MMP9 |
| EP2985295A1 (fr) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Anticorps spécifiques de MMP9 |
| TW201639573A (zh) | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
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