MA35070B1 - Traitements ophtalmiques - Google Patents
Traitements ophtalmiquesInfo
- Publication number
- MA35070B1 MA35070B1 MA36378A MA36378A MA35070B1 MA 35070 B1 MA35070 B1 MA 35070B1 MA 36378 A MA36378 A MA 36378A MA 36378 A MA36378 A MA 36378A MA 35070 B1 MA35070 B1 MA 35070B1
- Authority
- MA
- Morocco
- Prior art keywords
- sil
- compositions
- opioid
- analgesic
- pain
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 5
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 239000000314 lubricant Substances 0.000 abstract 2
- 229940005483 opioid analgesics Drugs 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 229940127557 pharmaceutical product Drugs 0.000 abstract 2
- 229960004380 tramadol Drugs 0.000 abstract 2
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 abstract 2
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 abstract 1
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 abstract 1
- 206010013774 Dry eye Diseases 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000607 artificial tear Substances 0.000 abstract 1
- 208000010217 blepharitis Diseases 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940014041 hyaluronate Drugs 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229960003943 hypromellose Drugs 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des compositions aqueuses appropriées pour une administration topique à l'Sil humain ou animal, contenant au moins un lubrifiant ophtalmique polymère soluble dans l'eau, tel que le hyaluronate, un gel de carbomère ou l'hypromellose, conjointement avec un analgésique soluble dans l'eau. L'analgésique peut être un opioïde, en particulier un opioïde ayant une affinité pour les récepteurs 5-HT, tels que le tramadole. Des taux typiques de tramadol devraient se situer dans la plage allant de 0,5 % à 1,0 % p/v. Les compositions aqueuses peuvent, par exemple, être utilisées comme larmes artificielles et comme lubrifiants ophtalmiques généraux pour le traitement d'états tels que la sécheresse oculaire ou la blépharite. Des compositions supplémentaires combinent des agents actifs du point de vue ophtalmologique, tels que des produits pharmaceutiques, avec des opioïdes, tel que le tramadol, en particulier. Ces compositions peuvent être utilisées pour traiter l'Sil tout en réduisant la douleur ou l'inconfort qui serait normalement produit par l'administration de ces produits pharmaceutiques particuliers à l'Sil, et tout en augmentant l'efficacité des produits pharmaceutiques. L'invention concerne également des compositions, contenant des opioïdes ayant une activité de récepteur 5-H, qui sont d'utilité générale dans le soulagement de la douleur dans et autour de l'Sil.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1105732.0A GB201105732D0 (en) | 2011-04-05 | 2011-04-05 | Ophthalmic lubricants |
| GBGB1105731.2A GB201105731D0 (en) | 2011-04-05 | 2011-04-05 | Topical analgesics |
| PCT/GB2012/000330 WO2012136969A2 (fr) | 2011-04-05 | 2012-04-05 | Traitements ophtalmiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA35070B1 true MA35070B1 (fr) | 2014-04-03 |
Family
ID=46086008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA36378A MA35070B1 (fr) | 2011-04-05 | 2012-04-05 | Traitements ophtalmiques |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20140088199A1 (fr) |
| EP (2) | EP3799866A1 (fr) |
| JP (2) | JP6148664B2 (fr) |
| KR (2) | KR102165246B1 (fr) |
| CN (2) | CN103687594A (fr) |
| BR (1) | BR112013025493A2 (fr) |
| CA (1) | CA2869280C (fr) |
| ES (1) | ES2836808T3 (fr) |
| HK (1) | HK1254720A1 (fr) |
| MA (1) | MA35070B1 (fr) |
| MX (1) | MX346312B (fr) |
| WO (1) | WO2012136969A2 (fr) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012136969A2 (fr) * | 2011-04-05 | 2012-10-11 | Anant Sharma | Traitements ophtalmiques |
| GB201217522D0 (en) * | 2012-10-01 | 2012-11-14 | Sharma Anant | ophthalmic therapy |
| GB2516138C (en) * | 2013-04-09 | 2015-12-09 | Cresset Biomolecular Discovery Ltd | The treatment of inflammatory disorders |
| ES2540151B1 (es) * | 2013-10-11 | 2016-02-29 | Farmalider S.A. | Composición farmacéutica de ibuprofeno y tramadol para uso oftálmico |
| RU2549472C1 (ru) * | 2013-12-26 | 2015-04-27 | Илья Александрович Марков | Фармацевтическая композиция в форме капель для профилактики и лечения аллергических заболеваний глаз |
| EP3091985B1 (fr) * | 2014-01-10 | 2024-05-08 | Manistee Therapeutics, Inc. | Prostanglandines pour leur utilisation topique dans le traitement des migraines. |
| WO2016172712A2 (fr) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Composition ophtalmique |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| WO2016022066A1 (fr) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Compositions pharmaceutiques pour blépharite et encroûtement des paupières liés à demodex |
| US9877964B2 (en) | 2015-02-24 | 2018-01-30 | Ocugen, Inc. | Methods and compositions for treating dry eye disease and other eye disorders |
| MX2017010544A (es) * | 2015-02-24 | 2018-06-18 | Univ Illinois | Metodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos del ojo. |
| EP3302426A4 (fr) | 2015-05-29 | 2018-12-05 | Sydnexis, Inc. | Formulations pharmaceutiques stabilisées de d2o |
| ES2604816B1 (es) * | 2015-09-09 | 2018-01-29 | Farmalider, S.A. | Composición farmacéutica de tramadol para uso oftálmico |
| ES2871199T3 (es) * | 2015-09-24 | 2021-10-28 | Matrix Biology Inst | Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas |
| CN108697665A (zh) * | 2015-09-30 | 2018-10-23 | 乔治·爱德华·霍格 | 局部镇痛性疼痛缓解制剂、其制备和使用方法 |
| CN105232449B (zh) * | 2015-10-30 | 2019-04-09 | 上海昊海生物科技股份有限公司 | 盐酸莫西沙星透明质酸钠缓释纳米凝胶及其制备方法 |
| WO2018071619A1 (fr) * | 2016-10-12 | 2018-04-19 | Ps Therapies Ltd | Larmes artificielles, lentilles de contact et compositions de véhicule pour médicament et leurs procédés d'utilisation |
| WO2018212846A1 (fr) | 2017-05-19 | 2018-11-22 | Ocugen, Inc. | Compositions ophtalmiques et leurs procédés d'utilisation |
| PL3634415T3 (pl) * | 2017-06-08 | 2026-04-07 | Eye Therapies, Llc | Kompozycje okulistyczne zawierające brymonidynę i ketotifen do zastosowania w leczeniu alergii |
| AU2018385766B2 (en) | 2017-12-15 | 2022-12-01 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| MX2018003456A (es) | 2017-12-21 | 2019-09-06 | Gruenenthal Gmbh | Combinacion farmaceutica en la forma de comprimidos en bicapa que comprende ketorolaco trometamina y tramadol clorhidrato, y su uso para el tratamiento del dolor. |
| CN111886001A (zh) * | 2018-03-13 | 2020-11-03 | 参天制药株式会社 | 滴眼型洗眼药用组合物 |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| FR3096890B1 (fr) * | 2019-06-07 | 2021-05-14 | H4 Orphan Pharma | Utilisation d’une molécule opioïde pour traiter l’œil sec et l’œil allergique. |
| WO2021018750A1 (fr) | 2019-07-26 | 2021-02-04 | Proqr Therapeutics Ii B.V. | Compositions ophtalmiques comprenant des polymères viscosifiants et des acides nucléiques |
| US11504269B2 (en) | 2019-11-19 | 2022-11-22 | Jennifer L. Fabian | Therapeutic bra |
| US20230077811A1 (en) * | 2020-02-11 | 2023-03-16 | Tufts Medical Center, Inc. | Activation of neuropeptide receptors on plasmacytoid dendritic cells to treat or prevent ocular diseases associated with neovascularization and inflammation |
| WO2021216909A1 (fr) * | 2020-04-23 | 2021-10-28 | Okogen, Inc. | Traitement de conjonctivite virale |
| CN112007028A (zh) * | 2020-09-03 | 2020-12-01 | 北京博纳致恒科技有限责任公司 | 一种复合睫状肌松弛剂的人工泪液及用途 |
| WO2022183051A1 (fr) * | 2021-02-26 | 2022-09-01 | Vyluma Inc. | Méthodes et formulations pour l'administration topique de gabapentinoïdes |
| WO2023285878A1 (fr) * | 2021-07-13 | 2023-01-19 | Aviation-Ophthalmology | Procédés de détection, de traitement et de prévention de maladies, troubles et états oculaires induits par gpr68 |
| WO2024010039A1 (fr) * | 2022-07-06 | 2024-01-11 | ロート製薬株式会社 | Composition ophtalmologique |
| JPWO2024010045A1 (fr) * | 2022-07-06 | 2024-01-11 | ||
| TW202408468A (zh) * | 2022-07-06 | 2024-03-01 | 日商樂敦製藥股份有限公司 | 眼科組成物 |
| JPWO2024010040A1 (fr) * | 2022-07-06 | 2024-01-11 | ||
| WO2025146828A1 (fr) * | 2024-01-05 | 2025-07-10 | ロート製薬株式会社 | Composition ophtalmique |
| WO2025159099A1 (fr) * | 2024-01-24 | 2025-07-31 | 国立大学法人北海道大学 | Composition pharmaceutique, agent de traitement du blépharospasme, agent de traitement de l'hypersensibilité ou de la dystonie, et souris de modèle de symptômes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6384043B1 (en) | 1993-02-01 | 2002-05-07 | Gholam A. Peyman | Methods of alleviating pain sensations of the denuded eye with opioid analgesics |
| US6017963A (en) * | 1995-11-14 | 2000-01-25 | Euro-Celtique, S.A. | Formulation for intranasal administration |
| ES2174337T3 (es) * | 1996-12-16 | 2002-11-01 | Alcon Lab Inc | Uso topico de los agonistas opioides kappa para el tratamiento del dolor ocular. |
| US6174878B1 (en) * | 1999-08-31 | 2001-01-16 | Alcon Laboratories, Inc. | Topical use of kappa opioid agonists to treat otic pain |
| JP2004143157A (ja) * | 2002-10-01 | 2004-05-20 | Taisho Pharmaceut Co Ltd | 点眼剤 |
| US20060172972A1 (en) * | 2002-12-20 | 2006-08-03 | Chakshu Research Inc | Formulation and method for administration of ophthalmologically active agents |
| US8236292B2 (en) | 2004-06-04 | 2012-08-07 | Camurus Ab | Liquid depot formulations |
| EP1611877A1 (fr) * | 2004-06-28 | 2006-01-04 | Universidade de Coimbra | Méthodes pour la préparation d'articles ophthalmiques thérapeutiques à la libération prolongée en utilisant des fluides compressés pour l'imprégnation des medicaments |
| WO2007057508A2 (fr) | 2005-11-18 | 2007-05-24 | Orion Corporation | Traitement de la douleur |
| US20070254841A1 (en) * | 2006-01-25 | 2007-11-01 | Ophthalmic Research Associates, Inc. | Formulations and methods for treating dry eye |
| WO2008153746A1 (fr) * | 2007-05-24 | 2008-12-18 | Aciex Therapeutics, Inc. | Formulations et procédés de traitement de l'œil sec |
| EP2311446A1 (fr) * | 2009-10-16 | 2011-04-20 | Laboratorios Del. Dr. Esteve, S.A. | Compositions comprenant du Tramadol et du Célécoxib pour le traitement de la douleur |
| WO2012136969A2 (fr) * | 2011-04-05 | 2012-10-11 | Anant Sharma | Traitements ophtalmiques |
-
2012
- 2012-04-05 WO PCT/GB2012/000330 patent/WO2012136969A2/fr not_active Ceased
- 2012-04-05 EP EP20200285.3A patent/EP3799866A1/fr active Pending
- 2012-04-05 CN CN201280025096.6A patent/CN103687594A/zh active Pending
- 2012-04-05 JP JP2014503208A patent/JP6148664B2/ja active Active
- 2012-04-05 CN CN201711200533.4A patent/CN107982211A/zh active Pending
- 2012-04-05 KR KR1020187038197A patent/KR102165246B1/ko active Active
- 2012-04-05 ES ES12721571T patent/ES2836808T3/es active Active
- 2012-04-05 EP EP12721571.3A patent/EP2694048B1/fr active Active
- 2012-04-05 US US14/009,397 patent/US20140088199A1/en not_active Abandoned
- 2012-04-05 BR BR112013025493A patent/BR112013025493A2/pt not_active Application Discontinuation
- 2012-04-05 CA CA2869280A patent/CA2869280C/fr active Active
- 2012-04-05 MA MA36378A patent/MA35070B1/fr unknown
- 2012-04-05 MX MX2013011314A patent/MX346312B/es active IP Right Grant
- 2012-04-05 KR KR1020137029016A patent/KR20140145948A/ko not_active Ceased
-
2016
- 2016-03-21 US US15/076,098 patent/US9913813B2/en active Active
-
2017
- 2017-03-07 JP JP2017043172A patent/JP6419876B2/ja active Active
-
2018
- 2018-10-26 HK HK18113731.7A patent/HK1254720A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6148664B2 (ja) | 2017-06-14 |
| EP3799866A1 (fr) | 2021-04-07 |
| JP6419876B2 (ja) | 2018-11-07 |
| BR112013025493A2 (pt) | 2017-03-01 |
| CA2869280A1 (fr) | 2012-10-11 |
| WO2012136969A3 (fr) | 2013-01-03 |
| US20160199320A1 (en) | 2016-07-14 |
| JP2014513073A (ja) | 2014-05-29 |
| US9913813B2 (en) | 2018-03-13 |
| CN107982211A (zh) | 2018-05-04 |
| MX2013011314A (es) | 2014-03-27 |
| KR102165246B1 (ko) | 2020-10-13 |
| WO2012136969A2 (fr) | 2012-10-11 |
| JP2017141243A (ja) | 2017-08-17 |
| ES2836808T3 (es) | 2021-06-28 |
| KR20140145948A (ko) | 2014-12-24 |
| KR20190004815A (ko) | 2019-01-14 |
| MX346312B (es) | 2017-03-15 |
| HK1254720A1 (zh) | 2019-07-26 |
| EP2694048B1 (fr) | 2020-10-07 |
| EP2694048A2 (fr) | 2014-02-12 |
| CA2869280C (fr) | 2020-03-10 |
| US20140088199A1 (en) | 2014-03-27 |
| CN103687594A (zh) | 2014-03-26 |
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