MA37809A1 - Administration de médicament biodégradable pour compositions hydrophobes - Google Patents

Administration de médicament biodégradable pour compositions hydrophobes

Info

Publication number
MA37809A1
MA37809A1 MA37809A MA37809A MA37809A1 MA 37809 A1 MA37809 A1 MA 37809A1 MA 37809 A MA37809 A MA 37809A MA 37809 A MA37809 A MA 37809A MA 37809 A1 MA37809 A1 MA 37809A1
Authority
MA
Morocco
Prior art keywords
drug delivery
biodegradable drug
hydrophobic compositions
polyester
polyethylene glycol
Prior art date
Application number
MA37809A
Other languages
English (en)
Other versions
MA37809B1 (fr
Inventor
Georges Gaudriault
Christophe Roberge
Original Assignee
Medincell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49117888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA37809(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medincell filed Critical Medincell
Publication of MA37809A1 publication Critical patent/MA37809A1/fr
Publication of MA37809B1 publication Critical patent/MA37809B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne des compositions pour l'administration de médicament biodégradable comprenant un copolymère tribloc contenant un polyester et un polyéthylèneglycol et un copolymère dibloc contenant un polyester et un polyéthylèneglycol à coiffe terminale, ainsi qu'au moins une substance pharmaceutiquement active ou substance active hydrophobe telle que l'acétate de médroxyprogestérone, le lévonorgestrel, la cyclosporine, la progestérone ou la bupivacaïne.
MA37809A 2012-06-27 2013-06-27 Administration de médicament biodégradable pour compositions hydrophobes MA37809B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261665192P 2012-06-27 2012-06-27
PCT/IB2013/001547 WO2014001904A1 (fr) 2012-06-27 2013-06-27 Administration de médicament biodégradable pour compositions hydrophobes

Publications (2)

Publication Number Publication Date
MA37809A1 true MA37809A1 (fr) 2017-07-31
MA37809B1 MA37809B1 (fr) 2018-12-31

Family

ID=49117888

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37809A MA37809B1 (fr) 2012-06-27 2013-06-27 Administration de médicament biodégradable pour compositions hydrophobes

Country Status (23)

Country Link
US (5) US20150150987A1 (fr)
EP (1) EP2866837B1 (fr)
JP (1) JP6134788B2 (fr)
KR (1) KR102189442B1 (fr)
CN (1) CN104582733B (fr)
AU (1) AU2013282891B2 (fr)
BR (1) BR112014031773B1 (fr)
CA (1) CA2877083C (fr)
CL (1) CL2014003531A1 (fr)
CO (1) CO7160098A2 (fr)
CR (1) CR20140581A (fr)
CU (1) CU24287B1 (fr)
EA (1) EA031522B1 (fr)
ES (1) ES2938586T3 (fr)
IL (1) IL236472B (fr)
IN (1) IN2014DN11063A (fr)
MA (1) MA37809B1 (fr)
MX (1) MX353280B (fr)
SG (1) SG11201408658PA (fr)
TN (1) TN2014000520A1 (fr)
UA (1) UA113549C2 (fr)
WO (2) WO2014001905A1 (fr)
ZA (1) ZA201409291B (fr)

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US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
CA3042642A1 (fr) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Comprime extrude anti-abus a liberation immediate
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3099313B1 (fr) * 2014-01-27 2021-04-21 Centre National De La Recherche Scientifique Analogues rétro-inverso de spadine à effets antidépresseurs accrus
EP3145489A1 (fr) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Formulations d'hormones substitutives combinées naturelles et traitement hormonal substitutif
CA2955229C (fr) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Forme posologique remplie de liquide anti-abus a liberation immediate
WO2016054197A1 (fr) * 2014-09-30 2016-04-07 University Of Tennessee Research Foundation Forme de gélification in situ pour l'administration de médicaments à action prolongée
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
FR3027522B1 (fr) 2014-10-27 2016-12-09 I Ceram Composition poreuse chargee en principe actif
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US20200155449A1 (en) 2015-11-16 2020-05-21 Medincell Method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
WO2017173071A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Composition pharmaceutique d'hormone stéroïde
WO2018081138A1 (fr) * 2016-10-24 2018-05-03 Yale University Implants contraceptifs biodégradables
WO2018172850A1 (fr) 2017-03-20 2018-09-27 Teva Pharmaceuticals International Gmbh Formulations d'olanzapine à libération prolongée
EP3655017B1 (fr) * 2017-07-17 2025-01-22 Medincell S.A. Composition pharmaceutique
GB2568526A (en) 2017-11-20 2019-05-22 Rebio Tech Oy Composition
CN108078911A (zh) * 2017-12-08 2018-05-29 复旦大学 用于动物避孕的热致水凝胶缓释兽药注射剂及其制备方法
CA3110250A1 (fr) 2018-08-22 2020-02-27 Bacainn Therapeutics, Ltd. Compositions de cyclosporine et methodes d'utilisation
GB201900258D0 (en) 2019-01-08 2019-02-27 Medincell Pharmaceutical composition
MX2022003051A (es) * 2019-09-13 2022-06-14 Medincell S A Formulaciones para la administracion de farmacos.
CN111700876A (zh) * 2020-03-12 2020-09-25 上海市肿瘤研究所 一种治疗系统性红斑狼疮的载药递送给药系统及其制备方法
WO2022129417A1 (fr) 2020-12-16 2022-06-23 Medincell Méthodes et compositions pour le traitement prophylactique du virus sars-cov-2 (covid-19)
FI20215186A1 (en) 2021-02-19 2022-08-20 Rebio Tech Oy Compositions for ophthalmic treatment
JP2024511353A (ja) 2021-03-17 2024-03-13 メドインセルル エス．エー． リスペリドン及び生分解性ポリマーを含む長時間作用型注射用製剤
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Also Published As

Publication number Publication date
EP2866837B1 (fr) 2022-12-14
BR112014031773B1 (pt) 2020-10-13
US20220354956A1 (en) 2022-11-10
WO2014001905A1 (fr) 2014-01-03
EA201492172A1 (ru) 2015-09-30
IL236472A0 (en) 2015-02-26
IL236472B (en) 2020-02-27
US20190160171A1 (en) 2019-05-30
IN2014DN11063A (fr) 2015-09-25
BR112014031773A2 (pt) 2017-06-27
MX2014015902A (es) 2015-07-17
WO2014001904A1 (fr) 2014-01-03
SG11201408658PA (en) 2015-02-27
CO7160098A2 (es) 2015-01-15
US20200085958A1 (en) 2020-03-19
UA113549C2 (xx) 2017-02-10
CN104582733B (zh) 2017-07-04
KR102189442B1 (ko) 2020-12-11
MA37809B1 (fr) 2018-12-31
CN104582733A (zh) 2015-04-29
CL2014003531A1 (es) 2015-08-28
US20210008216A1 (en) 2021-01-14
HK1208374A1 (en) 2016-03-04
CA2877083C (fr) 2020-10-06
MX353280B (es) 2018-01-05
AU2013282891B2 (en) 2018-04-12
CA2877083A1 (fr) 2014-01-02
CU20140148A7 (es) 2015-03-30
AU2013282891A1 (en) 2015-01-22
JP6134788B2 (ja) 2017-05-24
EP2866837A1 (fr) 2015-05-06
EA031522B1 (ru) 2019-01-31
CR20140581A (es) 2015-02-06
ES2938586T3 (es) 2023-04-12
US20150150987A1 (en) 2015-06-04
ZA201409291B (en) 2017-05-31
AU2013282891A2 (en) 2015-02-05
JP2015522001A (ja) 2015-08-03
CU24287B1 (es) 2017-12-08
KR20150027265A (ko) 2015-03-11
TN2014000520A1 (en) 2016-03-30

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