MA37888B1 - Composition pharmaceutique enrobée contenant du régorafenib - Google Patents
Composition pharmaceutique enrobée contenant du régorafenibInfo
- Publication number
- MA37888B1 MA37888B1 MA37888A MA37888A MA37888B1 MA 37888 B1 MA37888 B1 MA 37888B1 MA 37888 A MA37888 A MA 37888A MA 37888 A MA37888 A MA 37888A MA 37888 B1 MA37888 B1 MA 37888B1
- Authority
- MA
- Morocco
- Prior art keywords
- pharmaceutical composition
- composition containing
- coated pharmaceutical
- containing regorafenib
- regorafenib
- Prior art date
Links
- 239000002138 L01XE21 - Regorafenib Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- FNHKPVJBJVTLMP-UHFFFAOYSA-N regorafenib Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=C(F)C(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 FNHKPVJBJVTLMP-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004836 regorafenib Drugs 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne une composition pharmaceutique enrobée contenant du régorafenib, son hydrate, son solvat, son métabolite ou son sel pharmaceutiquement acceptable ou son polymorphe ainsi qu'un procédé de préparation et son utilisation pour le traitement de troubles.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12183331 | 2012-09-06 | ||
| PCT/US2013/058257 WO2014039677A1 (fr) | 2012-09-06 | 2013-09-05 | Composition pharmaceutique enrobée contenant du régorafenib |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA37888A1 MA37888A1 (fr) | 2018-07-31 |
| MA37888B1 true MA37888B1 (fr) | 2019-08-30 |
Family
ID=46963450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA37888A MA37888B1 (fr) | 2012-09-06 | 2013-09-05 | Composition pharmaceutique enrobée contenant du régorafenib |
Country Status (43)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| JP2016531151A (ja) * | 2013-09-13 | 2016-10-06 | バイエル ファーマ アクチエンゲゼルシャフト | レファメチニブを含有する医薬組成物 |
| CN104586808B (zh) * | 2014-12-27 | 2017-08-18 | 北京元延医药科技股份有限公司 | 抗肿瘤药物组合物 |
| CN105136956A (zh) * | 2015-09-11 | 2015-12-09 | 江苏嘉逸医药有限公司 | 一种快速测定瑞戈非尼含量的方法 |
| CN105267167A (zh) * | 2015-09-11 | 2016-01-27 | 江苏嘉逸医药有限公司 | 一种瑞戈非尼口服固体药物组合物的制备方法 |
| CN106880607A (zh) * | 2015-12-15 | 2017-06-23 | 北大方正集团有限公司 | 一种含有瑞戈非尼的口腔崩解片及其制备方法 |
| CN106880615A (zh) * | 2015-12-15 | 2017-06-23 | 北大方正集团有限公司 | 一种瑞戈非尼的口服固体制剂及其制备方法 |
| CN105496975B (zh) * | 2015-12-17 | 2019-01-04 | 河南润弘制药股份有限公司 | 一种瑞戈非尼片剂及其制备方法 |
| CN106913527A (zh) * | 2015-12-28 | 2017-07-04 | 江苏先声药业有限公司 | 一种瑞戈非尼速释微丸及其制备方法 |
| CN105879049B (zh) * | 2016-05-13 | 2019-03-26 | 浙江大学 | 一种瑞戈非尼与β-环糊精的包合物及其制备方法 |
| CN107661296A (zh) * | 2016-07-27 | 2018-02-06 | 江苏先声药业有限公司 | 一种瑞戈非尼固体分散体及其制备方法 |
| PE20200859A1 (es) * | 2017-06-02 | 2020-08-25 | Bayer Healthcare Llc | Combinacion farmaceutica que comprende regonafenib y nivolumab como anticancerigeno |
| MX2021000068A (es) * | 2018-07-06 | 2021-03-25 | Agios Pharmaceuticals Inc | Formas y composiciones farmaceuticas de ivosidenib. |
| CN111053751A (zh) * | 2018-10-16 | 2020-04-24 | 正大天晴药业集团股份有限公司 | 瑞戈非尼的缓释片剂及其制备方法 |
| TWI799599B (zh) * | 2019-06-06 | 2023-04-21 | 華納國際生物科技股份有限公司 | 醫藥或保健品自乳化固體分散組成物 |
| EP3861989A1 (fr) * | 2020-02-07 | 2021-08-11 | Bayer Aktiengesellschaft | Composition pharmaceutique contenant du régorafénib et un agent de stabilisation |
| CN112587485A (zh) * | 2021-01-08 | 2021-04-02 | 湖南南新制药股份有限公司 | 一种药物固体分散体及其制备方法 |
| CN113018274A (zh) * | 2021-03-10 | 2021-06-25 | 药源生物科技(启东)有限公司 | 一种含羟丙甲纤维素的药物组合物及其制备方法 |
| TR2023002707A2 (tr) * | 2023-03-10 | 2024-09-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Regorafenib içeren bir farmasötik bileşim. |
| WO2025242583A1 (fr) | 2024-05-24 | 2025-11-27 | Bayer Consumer Care Ag | Nouvelle formulation comprenant de l'élinzanétant dans une dispersion solide |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100137023A (ko) * | 2002-09-20 | 2010-12-29 | 안드렉스 랩스 엘엘씨 | 약제학적 정제 |
| CN1265793C (zh) * | 2002-11-18 | 2006-07-26 | 杭州容立医药科技有限公司 | 左西替利嗪伪麻黄碱复方口服制剂及制备方法 |
| EA010485B1 (ru) * | 2003-07-23 | 2008-10-30 | Байер Фамэсьютиклс Копэрейшн | Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты) |
| MY191349A (en) * | 2004-08-27 | 2022-06-17 | Bayer Pharmaceuticals Corp | New pharmaceutical compositions for the treatment of hyper-proliferative disorders |
| CA2633411A1 (fr) * | 2005-12-15 | 2007-06-21 | Bayer Healthcare Ag | Diaryle-urees pour le traitement de maladies inflammatoires de la peau, l'oeil et/ou l'oreille |
| AR062927A1 (es) * | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
| WO2008044111A1 (fr) * | 2006-10-13 | 2008-04-17 | Pfizer Products Inc. | Cachet de formulation pharmaceutique |
| US20100179184A1 (en) * | 2006-12-07 | 2010-07-15 | Matthew John Moon | Article of manufacture for prasugrel |
| EP2214651A1 (fr) * | 2007-10-25 | 2010-08-11 | Bayer Yakuhin, Ltd. | Comprimé enrobé sous presse contenant de la nifédipine et son procédé de préparation |
| AR081060A1 (es) * | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| CA2835364C (fr) * | 2011-05-20 | 2018-10-02 | Astrazeneca Uk Limited | Composition pharmaceutique de rosuvastatine calcique |
-
2013
- 2013-09-04 UY UY0001035006A patent/UY35006A/es active IP Right Grant
- 2013-09-04 AR ARP130103145A patent/AR092439A1/es not_active Application Discontinuation
- 2013-09-04 JO JOP/2013/0268A patent/JO3479B1/ar active
- 2013-09-05 CN CN202310409897.2A patent/CN116392484A/zh active Pending
- 2013-09-05 KR KR1020157008402A patent/KR102162036B1/ko active Active
- 2013-09-05 PE PE2015000289A patent/PE20151005A1/es active IP Right Grant
- 2013-09-05 PL PL13762967T patent/PL2892507T3/pl unknown
- 2013-09-05 CN CN201380049461.1A patent/CN104902878A/zh active Pending
- 2013-09-05 PT PT137629671T patent/PT2892507T/pt unknown
- 2013-09-05 MY MYPI2015700672A patent/MY176135A/en unknown
- 2013-09-05 HU HUE13762967A patent/HUE032758T2/en unknown
- 2013-09-05 US US14/018,516 patent/US20140065212A1/en not_active Abandoned
- 2013-09-05 MX MX2015002815A patent/MX359922B/es active IP Right Grant
- 2013-09-05 AU AU2013312531A patent/AU2013312531B2/en active Active
- 2013-09-05 SG SG11201501683WA patent/SG11201501683WA/en unknown
- 2013-09-05 JP JP2015531194A patent/JP6445436B2/ja active Active
- 2013-09-05 BR BR112015004936-2A patent/BR112015004936B1/pt active IP Right Grant
- 2013-09-05 CN CN202310410047.4A patent/CN116392485A/zh active Pending
- 2013-09-05 CU CUP2015000020A patent/CU24244B1/es unknown
- 2013-09-05 DK DK13762967.1T patent/DK2892507T3/en active
- 2013-09-05 LT LTEP13762967.1T patent/LT2892507T/lt unknown
- 2013-09-05 MA MA37888A patent/MA37888B1/fr unknown
- 2013-09-05 NZ NZ705578A patent/NZ705578A/en unknown
- 2013-09-05 EP EP17153541.2A patent/EP3243508A1/fr not_active Withdrawn
- 2013-09-05 CA CA2883767A patent/CA2883767C/fr active Active
- 2013-09-05 IN IN1673DEN2015 patent/IN2015DN01673A/en unknown
- 2013-09-05 UA UAA201502818A patent/UA115994C2/uk unknown
- 2013-09-05 EP EP13762967.1A patent/EP2892507B1/fr active Active
- 2013-09-05 AP AP2015008292A patent/AP2015008292A0/xx unknown
- 2013-09-05 SI SI201330621T patent/SI2892507T1/sl unknown
- 2013-09-05 WO PCT/US2013/058257 patent/WO2014039677A1/fr not_active Ceased
- 2013-09-05 CN CN202010052300.XA patent/CN111249247A/zh active Pending
- 2013-09-05 HR HRP20170620TT patent/HRP20170620T1/hr unknown
- 2013-09-05 RS RS20170400A patent/RS56019B1/sr unknown
- 2013-09-05 ES ES13762967.1T patent/ES2623205T3/es active Active
- 2013-09-05 EA EA201590520A patent/EA027685B1/ru not_active IP Right Cessation
- 2013-09-05 HK HK16102327.2A patent/HK1214170A1/zh unknown
- 2013-09-05 CN CN202310406916.6A patent/CN116392598A/zh active Pending
- 2013-09-05 TW TW102131928A patent/TWI640329B/zh active
-
2015
- 2015-02-22 IL IL237350A patent/IL237350B/en active IP Right Grant
- 2015-03-02 ZA ZA2015/01394A patent/ZA201501394B/en unknown
- 2015-03-03 PH PH12015500460A patent/PH12015500460A1/en unknown
- 2015-03-04 SA SA515360113A patent/SA515360113B1/ar unknown
- 2015-03-05 CL CL2015000544A patent/CL2015000544A1/es unknown
- 2015-03-05 GT GT201500053A patent/GT201500053A/es unknown
- 2015-03-05 CO CO15050805A patent/CO7310528A2/es unknown
- 2015-03-05 CR CR20150114A patent/CR20150114A/es unknown
-
2017
- 2017-04-21 CY CY20171100450T patent/CY1118839T1/el unknown
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