MA39441A1 - Composition d'insuline a action rapide - Google Patents

Composition d'insuline a action rapide

Info

Publication number
MA39441A1
MA39441A1 MA39441A MA39441A MA39441A1 MA 39441 A1 MA39441 A1 MA 39441A1 MA 39441 A MA39441 A MA 39441A MA 39441 A MA39441 A MA 39441A MA 39441 A1 MA39441 A1 MA 39441A1
Authority
MA
Morocco
Prior art keywords
fast
acting insulin
insulin composition
insulin analog
composition
Prior art date
Application number
MA39441A
Other languages
English (en)
Inventor
Micheal Edward Christe
Thomas Andrew Hardy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA39441(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA39441A1 publication Critical patent/MA39441A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur une composition d'insuline humaine ou d'analogue d'insuline qui comprend du tréprostinil et qui possède une action pharmacocinétique plus rapide par rapport aux formulations commerciales de produits analogues d'insuline existants.
MA39441A 2014-05-08 2015-05-04 Composition d'insuline a action rapide MA39441A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08
PCT/US2015/029010 WO2015171484A1 (fr) 2014-05-08 2015-05-04 Compositions d'insuline à action rapide

Publications (1)

Publication Number Publication Date
MA39441A1 true MA39441A1 (fr) 2017-06-30

Family

ID=53189204

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39441A MA39441A1 (fr) 2014-05-08 2015-05-04 Composition d'insuline a action rapide

Country Status (36)

Country Link
US (2) US9439952B2 (fr)
EP (3) EP3536380B8 (fr)
JP (1) JP6050902B2 (fr)
KR (1) KR101858890B1 (fr)
CN (1) CN106456717B (fr)
AP (1) AP2016009525A0 (fr)
AR (1) AR100155A1 (fr)
AU (1) AU2015256355B2 (fr)
BR (1) BR112016024357B1 (fr)
CA (1) CA2945188C (fr)
CL (1) CL2016002772A1 (fr)
CY (2) CY1121669T1 (fr)
DK (2) DK3140008T3 (fr)
EA (1) EA031134B1 (fr)
ES (2) ES2891983T3 (fr)
HR (2) HRP20190777T1 (fr)
HU (2) HUE055742T2 (fr)
IL (1) IL248350B (fr)
JO (1) JO3624B1 (fr)
LT (2) LT3140008T (fr)
MA (1) MA39441A1 (fr)
ME (1) ME03384B (fr)
MX (1) MX367521B (fr)
NZ (1) NZ724919A (fr)
PE (1) PE20161408A1 (fr)
PH (1) PH12016502195A1 (fr)
PL (2) PL3536380T3 (fr)
PT (2) PT3536380T (fr)
RS (2) RS58726B1 (fr)
SG (1) SG11201608424WA (fr)
SI (2) SI3140008T1 (fr)
TN (1) TN2016000443A1 (fr)
TR (1) TR201906843T4 (fr)
TW (1) TWI685348B (fr)
UA (1) UA124919C2 (fr)
WO (1) WO2015171484A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
CN104902922B (zh) 2012-11-13 2017-12-12 阿道恰公司 包含经取代阴离子化合物的速效胰岛素制剂
EP3712142B1 (fr) 2013-01-11 2022-07-06 Corsair Pharma, Inc. Promédicaments de tréprostinil
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
WO2017015760A1 (fr) * 2015-07-28 2017-02-02 Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et Humaines, S.E.C. Préparation pharmaceutique pour améliorer l'absorption et l'action hypoglycémique postprandiale de l'insuline
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
CA3012679C (fr) * 2016-01-29 2023-12-12 Mannkind Corporation Inhalateur a poudre seche
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
JP7220650B2 (ja) 2016-09-26 2023-02-10 ユナイテッド セラピューティクス コーポレイション トレプロスチニルプロドラッグ
JP2019529506A (ja) 2016-09-29 2019-10-17 アレコル リミテッド 新規の製剤
PE20210857A1 (es) 2016-12-16 2021-05-18 Novo Nordisk As Composiciones farmaceuticas que contienen insulina
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
CN110662551B (zh) 2017-06-01 2023-07-18 伊莱利利公司 速效胰岛素组合物
US20210113763A1 (en) 2018-04-04 2021-04-22 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
US12357562B2 (en) 2018-04-04 2025-07-15 Arecor Limited Injection pen system for the delivery of an insulin compound
KR102833828B1 (ko) * 2018-04-04 2025-07-15 아레콜 리미티드 인슐린 화합물의 전달을 위한 의료용 주입 펌프 시스템
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
ES2976468T3 (es) 2018-09-18 2024-08-01 Lilly Co Eli Sal de treprostinil erbumina
US10799564B1 (en) * 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
EP4017588A1 (fr) 2019-08-23 2022-06-29 United Therapeutics Corporation Promédicaments de tréprostinil
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
JP2023523557A (ja) 2020-04-17 2023-06-06 ユナイテッド セラピューティクス コーポレイション 間質性肺疾患の治療における使用のためのトレプロスチニル
IL298591A (en) 2020-06-09 2023-01-01 United Therapeutics Corp Pomeryl dictopiperidine prodrugs of treprostinil
TW202214292A (zh) * 2020-06-30 2022-04-16 大陸商江蘇恆瑞醫藥股份有限公司 速效胰島素組成物及其醫藥用途
KR20250133451A (ko) 2020-12-14 2025-09-05 유나이티드 쎄러퓨틱스 코포레이션 트레프로스티닐 프로드러그로 질환을 치료하는 방법
JP2024510930A (ja) 2021-03-03 2024-03-12 ユナイテッド セラピューティクス コーポレイション トレプロスチニル及びそのプロドラッグの乾燥粉末組成物、及び、さらに（ｅ）－３，６－ビス［４－（ｎ－カルボニル－２－プロペニル）アミドブチル］－２，５－ジケトピペラジン（ｆｄｋｐ）を含む乾燥粉末組成物
EP4516297A4 (fr) * 2022-04-29 2026-02-25 Zhaoke pharmaceutical guangzhou co ltd Brume douce de tréprostinil à inhaler

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DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
EP1432430A4 (fr) * 2001-08-28 2006-05-10 Lilly Co Eli Pre-melanges de polypeptide glp-1 et d'insuline basale
JP5599543B2 (ja) 2002-05-07 2014-10-01 ノヴォ ノルディスク アー／エス 単量体インスリン及びアシル化インスリンを含む可溶性製剤
WO2005099680A2 (fr) * 2004-04-12 2005-10-27 United Therapeutics, Inc. Utilisation de treprostinile pour traiter des ulceres diabetiques neuropathiques du pied
EP2545920A1 (fr) * 2007-08-22 2013-01-16 Abbott GmbH & Co. KG Thérapie pour complications du diabète
DK2328636T3 (da) 2008-08-28 2013-09-02 Medingo Ltd Anordning til forbedret subkutan insulinabsorption
CN102164487A (zh) * 2008-09-25 2011-08-24 阿拉迪姆公司 曲前列素的深肺部递送
KR101775000B1 (ko) 2009-06-26 2017-09-04 노보 노르디스크 에이/에스 인슐린, 니코틴아미드 및 아미노산을 포함하는 제제
CN102655866B (zh) * 2009-11-13 2013-11-13 东丽株式会社 糖尿病的治疗或预防药
KR20140030125A (ko) 2010-12-14 2014-03-11 노보 노르디스크 에이/에스 인슐린, 니코틴아미드 및 아미노산을 포함하는 제제
MX349950B (es) * 2011-08-12 2017-08-22 Ascendis Pharma As Profarmacos de treprostinil enlazados a un portador.
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US20150065423A1 (en) 2013-08-30 2015-03-05 Perosphere, Inc. Rapid acting injectable formulations
WO2015120457A1 (fr) 2014-02-10 2015-08-13 Biodel Inc. Formulations d'insuline à action ultrarapide stabilisées

Also Published As

Publication number Publication date
CA2945188A1 (fr) 2015-11-12
TN2016000443A1 (en) 2018-04-04
PH12016502195B1 (en) 2017-02-06
EA201691911A1 (ru) 2017-02-28
US20160367640A1 (en) 2016-12-22
DK3536380T3 (da) 2021-08-02
EP3140008B1 (fr) 2019-04-17
LT3536380T (lt) 2021-08-10
CN106456717A (zh) 2017-02-22
JP2016523807A (ja) 2016-08-12
TW201625291A (zh) 2016-07-16
PH12016502195A1 (en) 2017-02-06
KR101858890B1 (ko) 2018-05-16
CY1121669T1 (el) 2020-07-31
AU2015256355A1 (en) 2016-10-27
CA2945188C (fr) 2018-12-11
EP3536380B8 (fr) 2021-09-22
HRP20211415T1 (hr) 2021-12-10
EP3536380A1 (fr) 2019-09-11
PE20161408A1 (es) 2016-12-28
EA031134B1 (ru) 2018-11-30
US10172922B2 (en) 2019-01-08
CL2016002772A1 (es) 2017-06-09
CN106456717B (zh) 2020-01-17
AU2015256355B2 (en) 2017-09-14
RS62291B1 (sr) 2021-09-30
US9439952B2 (en) 2016-09-13
UA124919C2 (uk) 2021-12-15
SI3140008T1 (sl) 2019-06-28
ME03384B (fr) 2020-01-20
MX367521B (es) 2019-08-26
HUE055742T2 (hu) 2021-12-28
HRP20190777T1 (hr) 2019-08-23
TWI685348B (zh) 2020-02-21
LT3140008T (lt) 2019-05-27
WO2015171484A1 (fr) 2015-11-12
DK3140008T3 (da) 2019-06-24
IL248350A0 (en) 2016-11-30
IL248350B (en) 2020-03-31
SI3536380T1 (sl) 2021-09-30
EP3536380B1 (fr) 2021-07-07
PL3140008T3 (pl) 2019-09-30
SG11201608424WA (en) 2016-11-29
HUE044370T2 (hu) 2019-10-28
US20160129087A1 (en) 2016-05-12
EP3943155A1 (fr) 2022-01-26
ES2733639T3 (es) 2019-12-02
MX2016014643A (es) 2017-03-06
BR112016024357A2 (pt) 2017-10-10
ES2891983T3 (es) 2022-02-01
NZ724919A (en) 2018-01-26
PT3140008T (pt) 2019-06-25
AP2016009525A0 (en) 2016-10-31
CY1124454T1 (el) 2022-07-22
JO3624B1 (ar) 2020-08-27
KR20160133567A (ko) 2016-11-22
EP3140008A1 (fr) 2017-03-15
PL3536380T3 (pl) 2021-12-27
JP6050902B2 (ja) 2016-12-21
BR112016024357B1 (pt) 2022-08-23
TR201906843T4 (tr) 2019-05-21
RS58726B1 (sr) 2019-06-28
AR100155A1 (es) 2016-09-14
PT3536380T (pt) 2021-09-02

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