MA41311B1 - Peptides antagonistes du cgrp - Google Patents
Peptides antagonistes du cgrpInfo
- Publication number
- MA41311B1 MA41311B1 MA41311A MA41311A MA41311B1 MA 41311 B1 MA41311 B1 MA 41311B1 MA 41311 A MA41311 A MA 41311A MA 41311 A MA41311 A MA 41311A MA 41311 B1 MA41311 B1 MA 41311B1
- Authority
- MA
- Morocco
- Prior art keywords
- cgrp antagonist
- antagonist peptides
- compounds
- formula
- peptides
- Prior art date
Links
- 229940127597 CGRP antagonist Drugs 0.000 title abstract 2
- 239000003735 calcitonin gene related peptide receptor antagonist Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pyridine Compounds (AREA)
Abstract
La présente invention concerne des composés de formule (i) ou un sel pharmaceutiquement acceptable de celui-ci : dans laquelle m, p, a, ar1, ar2, ar3, r1, r2 et r3 sont tels que définis dans la description. Les composés de formule (i) peuvent être utilisés comme antagonistes de cgrp et peuvent être utilisés pour traiter
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562100371P | 2015-01-06 | 2015-01-06 | |
| PCT/EP2016/050110 WO2016110499A1 (fr) | 2015-01-06 | 2016-01-06 | Peptides antagonistes du cgrp |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA41311A MA41311A (fr) | 2017-11-14 |
| MA41311B1 true MA41311B1 (fr) | 2022-10-31 |
Family
ID=55071041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA41311A MA41311B1 (fr) | 2015-01-06 | 2016-01-06 | Peptides antagonistes du cgrp |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US9969775B2 (fr) |
| EP (1) | EP3242882B1 (fr) |
| JP (1) | JP6929227B2 (fr) |
| KR (1) | KR102713739B1 (fr) |
| CN (1) | CN107207567B (fr) |
| AR (1) | AR103499A1 (fr) |
| AU (1) | AU2016206059B2 (fr) |
| BR (1) | BR112017013413A2 (fr) |
| CL (1) | CL2017001761A1 (fr) |
| CO (1) | CO2017007940A2 (fr) |
| DK (1) | DK3242882T3 (fr) |
| EA (1) | EA032082B1 (fr) |
| ES (1) | ES2924410T3 (fr) |
| HR (1) | HRP20220941T1 (fr) |
| HU (1) | HUE059379T2 (fr) |
| IL (1) | IL252903B (fr) |
| JO (1) | JO3669B1 (fr) |
| LT (1) | LT3242882T (fr) |
| MA (1) | MA41311B1 (fr) |
| MD (1) | MD3242882T2 (fr) |
| MX (1) | MX387920B (fr) |
| MY (1) | MY196439A (fr) |
| PH (1) | PH12017501214A1 (fr) |
| PL (1) | PL3242882T3 (fr) |
| PT (1) | PT3242882T (fr) |
| RS (1) | RS63467B1 (fr) |
| SA (1) | SA517381865B1 (fr) |
| SG (1) | SG11201705306UA (fr) |
| SI (1) | SI3242882T1 (fr) |
| TN (1) | TN2017000248A1 (fr) |
| TW (1) | TWI717331B (fr) |
| UA (1) | UA121490C2 (fr) |
| WO (1) | WO2016110499A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200353088A1 (en) * | 2017-11-06 | 2020-11-12 | Auckland Uniservices Limited | Peptide conjugate cgrp receptor antagonists and methods of preparation and uses thereof |
| WO2025202938A1 (fr) | 2024-03-26 | 2025-10-02 | Nuvie Bio, Inc. | Composition pharmaceutique comprenant un antagoniste du récepteur cgrp pour le traitement de la migraine aiguë |
| EP4647082A1 (fr) | 2024-05-08 | 2025-11-12 | NUVIE BIO, Inc. | Composition pharmaceutique comprenant un antagoniste du récepteur du cgrp pour le traitement de la migraine aiguë |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6268474B1 (en) * | 1998-04-30 | 2001-07-31 | Creighton University | Peptide antagonists of CGRP-receptor superfamily and methods of use |
| TW200533398A (en) | 2004-03-29 | 2005-10-16 | Bristol Myers Squibb Co | Novel therapeutic agents for the treatment of migraine |
| US20060004185A1 (en) * | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US7659264B2 (en) * | 2004-10-07 | 2010-02-09 | Merck Sharp & Dohme Corp. | CGRP receptor antagonists |
| RU2007131267A (ru) * | 2005-01-17 | 2009-02-27 | Йерини Аг (De) | АНТАГОНИСТЫ РЕЦЕПТОРА С5a |
| CA2599925A1 (fr) * | 2005-03-14 | 2006-09-21 | Merck & Co., Inc. | Antagonistes du recepteur du cgrp |
| US8168592B2 (en) * | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
| EP3069731A1 (fr) * | 2005-11-14 | 2016-09-21 | Labrys Biologics Inc. | Antagonistes d'anticorps dirigés contre un peptide associé au gène de la calcitonine et procédés les utilisant |
| EP2027106A2 (fr) * | 2006-06-13 | 2009-02-25 | Vertex Pharmaceuticals Incorporated | Antagonistes du récepteur du cgrp |
| KR101855242B1 (ko) | 2012-01-26 | 2018-05-09 | 크리스토퍼 제이. 소레스 | 펩타이드 호르몬의 칼시토닌 cgrp 패밀리의 펩타이드 길항제 및 그의 용도 |
-
2016
- 2016-01-04 JO JOP/2016/0002A patent/JO3669B1/ar active
- 2016-01-05 AR ARP160100008A patent/AR103499A1/es active IP Right Grant
- 2016-01-05 TW TW105100158A patent/TWI717331B/zh active
- 2016-01-06 RS RS20220739A patent/RS63467B1/sr unknown
- 2016-01-06 ES ES16700059T patent/ES2924410T3/es active Active
- 2016-01-06 EA EA201791456A patent/EA032082B1/ru not_active IP Right Cessation
- 2016-01-06 EP EP16700059.5A patent/EP3242882B1/fr active Active
- 2016-01-06 CN CN201680005041.7A patent/CN107207567B/zh active Active
- 2016-01-06 US US15/540,460 patent/US9969775B2/en active Active
- 2016-01-06 DK DK16700059.5T patent/DK3242882T3/da active
- 2016-01-06 BR BR112017013413-6A patent/BR112017013413A2/pt active Search and Examination
- 2016-01-06 MA MA41311A patent/MA41311B1/fr unknown
- 2016-01-06 SI SI201631576T patent/SI3242882T1/sl unknown
- 2016-01-06 MX MX2017008893A patent/MX387920B/es unknown
- 2016-01-06 KR KR1020177021133A patent/KR102713739B1/ko active Active
- 2016-01-06 PL PL16700059.5T patent/PL3242882T3/pl unknown
- 2016-01-06 WO PCT/EP2016/050110 patent/WO2016110499A1/fr not_active Ceased
- 2016-01-06 TN TN2017000248A patent/TN2017000248A1/en unknown
- 2016-01-06 UA UAA201708029A patent/UA121490C2/uk unknown
- 2016-01-06 LT LTEPPCT/EP2016/050110T patent/LT3242882T/lt unknown
- 2016-01-06 JP JP2017553460A patent/JP6929227B2/ja active Active
- 2016-01-06 HU HUE16700059A patent/HUE059379T2/hu unknown
- 2016-01-06 AU AU2016206059A patent/AU2016206059B2/en active Active
- 2016-01-06 MY MYPI2017702432A patent/MY196439A/en unknown
- 2016-01-06 SG SG11201705306UA patent/SG11201705306UA/en unknown
- 2016-01-06 HR HRP20220941TT patent/HRP20220941T1/hr unknown
- 2016-01-06 MD MDE20170266T patent/MD3242882T2/ro unknown
- 2016-01-06 PT PT167000595T patent/PT3242882T/pt unknown
-
2017
- 2017-06-14 IL IL252903A patent/IL252903B/en active IP Right Grant
- 2017-06-29 PH PH12017501214A patent/PH12017501214A1/en unknown
- 2017-07-03 CL CL2017001761A patent/CL2017001761A1/es unknown
- 2017-07-04 SA SA517381865A patent/SA517381865B1/ar unknown
- 2017-08-04 CO CONC2017/0007940A patent/CO2017007940A2/es unknown
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