MA41670A1 - Anticorps se liant a tau - Google Patents

Anticorps se liant a tau

Info

Publication number
MA41670A1
MA41670A1 MA41670A MA41670A MA41670A1 MA 41670 A1 MA41670 A1 MA 41670A1 MA 41670 A MA41670 A MA 41670A MA 41670 A MA41670 A MA 41670A MA 41670 A1 MA41670 A1 MA 41670A1
Authority
MA
Morocco
Prior art keywords
tau
antibodies binding
antibodies
binding
relates
Prior art date
Application number
MA41670A
Other languages
English (en)
Inventor
Terence Seward Baker
Georges Mairet-Coello
Patrick Downey
Jean-Philippe Courade
David Edward Ormonde Knight
David James Mcmillan
Robert Anthony Griffin
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53524640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA41670(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of MA41670A1 publication Critical patent/MA41670A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des anticorps se liant à tau et des fragments de liaison de ces anticorps
MA41670A 2015-07-06 2016-07-05 Anticorps se liant a tau MA41670A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15175522 2015-07-06
PCT/EP2016/065813 WO2017005734A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau

Publications (1)

Publication Number Publication Date
MA41670A1 true MA41670A1 (fr) 2018-05-31

Family

ID=53524640

Family Applications (2)

Application Number Title Priority Date Filing Date
MA042377A MA42377A (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau
MA41670A MA41670A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant a tau

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA042377A MA42377A (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau

Country Status (30)

Country Link
US (4) US10287343B2 (fr)
EP (2) EP3319983B1 (fr)
JP (3) JP6630426B2 (fr)
KR (2) KR102770650B1 (fr)
CN (1) CN107849104B (fr)
AR (1) AR105267A1 (fr)
AU (1) AU2016289755C1 (fr)
CA (1) CA2991451A1 (fr)
CL (1) CL2018000043A1 (fr)
CO (1) CO2017012971A2 (fr)
EA (1) EA037092B1 (fr)
EC (1) ECSP18000887A (fr)
ES (1) ES3060419T3 (fr)
HR (1) HRP20260348T1 (fr)
IL (1) IL256685B (fr)
MA (2) MA42377A (fr)
MD (1) MD3319983T2 (fr)
MX (1) MX2017015817A (fr)
MY (1) MY193677A (fr)
PE (1) PE20180481A1 (fr)
PH (1) PH12017502207B1 (fr)
RS (1) RS67937B1 (fr)
SG (1) SG10202010735PA (fr)
SM (1) SMT202600068T1 (fr)
TN (1) TN2017000539A1 (fr)
TW (1) TWI745295B (fr)
UA (1) UA124616C2 (fr)
UY (1) UY36773A (fr)
WO (1) WO2017005734A1 (fr)
ZA (1) ZA201800027B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA126272C2 (uk) 2015-06-05 2022-09-14 Дженентек, Інк. Антитіло проти тау-білка та спосіб його застосування
MX2017015908A (es) 2015-07-06 2018-03-15 Ucb Biopharma Sprl Anticuerpos de union a tau.
EA037092B1 (ru) 2015-07-06 2021-02-04 Юсб Биофарма Срл Тау-связывающие антитела
AR110321A1 (es) 2016-12-07 2019-03-20 Genentech Inc Anticuerpos antitau y métodos de uso
KR20240035636A (ko) 2016-12-07 2024-03-15 제넨테크, 인크. 항-타우 항체 및 이의 이용 방법
US20200087390A1 (en) 2016-12-21 2020-03-19 Amgen Inc. Anti-tnf alpha antibody formulations
SG11201907422RA (en) 2017-02-17 2019-09-27 Denali Therapeutics Inc Anti-tau antibodies and methods of use thereof
JP2018139530A (ja) 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
NZ762251A (en) 2017-10-16 2025-12-19 Eisai R&D Man Co Ltd Anti-tau antibodies and uses thereof
EP3894438A1 (fr) * 2018-12-13 2021-10-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Nouvel anticorps à domaine unique d'épitope dirigé contre tau svqivykpv
MX2022001817A (es) * 2019-08-13 2022-03-11 Washington University St Louis Metodos para detectar isoformas de la region de union a microtubulos (mtbr) tau y uso de las mismas.
CN115335406B (zh) 2020-02-12 2026-01-30 伊莱利利公司 抗体或抗原-结合片段的结晶
EP4171633A1 (fr) 2020-06-25 2023-05-03 Merck Sharp & Dohme LLC Anticorps à haute affinité ciblant la protéine tau phosphorylée à la position 413 de sérine
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
CN120019071A (zh) 2022-09-15 2025-05-16 沃雅戈治疗公司 Tau结合化合物
WO2024107745A1 (fr) * 2022-11-14 2024-05-23 Washington University Procédés de détection de mtbr-tau de lcr et leurs utilisations
WO2025122634A1 (fr) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions et méthodes pour le traitement de troubles liés à la protéine tau
WO2025171285A1 (fr) * 2024-02-09 2025-08-14 University Of Notre Dame Du Lac Protéomimétiques tau
WO2025196217A1 (fr) 2024-03-21 2025-09-25 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau
WO2026057816A1 (fr) 2024-09-13 2026-03-19 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau
WO2026093448A1 (fr) * 2024-10-30 2026-05-07 Universiteit Utrecht Holding B.V. Anticorps à domaine unique ciblant le facteur de croissance de type egf se liant à l'héparine

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
DK336987D0 (da) 1987-07-01 1987-07-01 Novo Industri As Immobiliseringsmetode
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8719042D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
GB8907617D0 (en) 1989-04-05 1989-05-17 Celltech Ltd Drug delivery system
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
GB9120467D0 (en) 1991-09-26 1991-11-06 Celltech Ltd Anti-hmfg antibodies and process for their production
FR2716640B1 (fr) 1994-02-28 1996-05-03 Procedes Machines Speciales Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion.
US6372716B1 (en) 1994-04-26 2002-04-16 Genetics Institute, Inc. Formulations for factor IX
US6685940B2 (en) 1995-07-27 2004-02-03 Genentech, Inc. Protein formulation
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
US6566329B1 (en) 1999-06-28 2003-05-20 Novo Nordisk A/S Freeze-dried preparation of human growth hormone
AT500379B8 (de) 2001-02-02 2009-08-15 Axon Neuroscience Tau-proteine
US6908963B2 (en) 2001-10-09 2005-06-21 Nektar Therapeutics Al, Corporation Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
HUE026278T2 (en) 2003-07-01 2016-05-30 Ucb Biopharma Sprl Modified Fab antibody fragments
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
GB0412181D0 (en) 2004-06-01 2004-06-30 Celltech R&D Ltd Biological products
CN1721437A (zh) * 2004-07-13 2006-01-18 中南大学 一种与Tau蛋白相关的多肽抗原及抗体
JP5364870B2 (ja) 2005-08-19 2013-12-11 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリン及びその使用
GB0614780D0 (en) 2006-07-25 2006-09-06 Ucb Sa Biological products
GB0619291D0 (en) 2006-09-29 2006-11-08 Ucb Sa Altered antibodies
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
US8629246B2 (en) 2007-09-26 2014-01-14 Ucb Pharma S.A. Dual specificity antibody fusions
CN101307108B (zh) * 2008-06-25 2012-04-04 南京川博生物技术有限公司 抗磷酸化Tau蛋白抗体及其在AD症异常磷酸化Tau蛋白水平测定上的用途
WO2010035012A1 (fr) 2008-09-26 2010-04-01 Ucb Pharma S.A. Produits biologiques
US8921314B2 (en) 2008-10-15 2014-12-30 Angiochem, Inc. Conjugates of GLP-1 agonists and uses thereof
MX2011005963A (es) 2008-12-05 2011-09-01 Angiochem Inc Conjugados de neurotensina o analogos de neurotensina y sus usos.
CA2745527A1 (fr) 2008-12-05 2010-06-10 Angiochem Inc. Conjugues de leptine et d'analogues de leptine et leurs applications
US8609097B2 (en) * 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
ES2667258T3 (es) 2009-09-10 2018-05-10 Ucb Biopharma Sprl Anticuerpos multivalentes
MX2012004247A (es) 2009-10-06 2012-06-25 Angiochem Inc Composiciones y metodos para el transporte de agentes terapeuticos.
PE20140218A1 (es) 2010-10-07 2014-03-01 Ac Inmune S A Composicion farmaceutica
SG189174A1 (en) * 2010-10-11 2013-05-31 Biogen Idec Internat Neuroscience Gmbh Human anti-tau antibodies
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
US9518101B2 (en) 2011-09-19 2016-12-13 Axon Neuroscience Se Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
WO2013063086A1 (fr) * 2011-10-24 2013-05-02 Intellect Neurosciences, Inc. Compositions et méthodes de traitement de protéinopathies
US9803004B2 (en) 2011-11-11 2017-10-31 Ucb Biopharma Sprl Albumin binding antibodies and binding fragments thereof
PT2794654T (pt) * 2011-12-20 2019-09-10 Janssen Biotech Inc Anticorpos anti-phf-tau e suas utilizações
JP6345655B2 (ja) 2012-07-03 2018-06-20 ワシントン・ユニバーシティＷａｓｈｉｎｇｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ タウに対する抗体
DK2885010T3 (da) * 2012-08-16 2020-02-03 Ipierian Inc Fremgangsmåder til behandling med tauopati
HRP20201422T1 (hr) 2012-12-21 2021-02-19 Biogen Ma Inc. Ljudska anti-tau antitijela
CA2874083C (fr) * 2014-12-05 2024-01-02 Universite Laval Polypeptides liant le tdp-43 utiles pour le traitement de maladies neurodegeneratives
MX2017015908A (es) 2015-07-06 2018-03-15 Ucb Biopharma Sprl Anticuerpos de union a tau.
EA037092B1 (ru) 2015-07-06 2021-02-04 Юсб Биофарма Срл Тау-связывающие антитела

Also Published As

Publication number Publication date
US20190284267A1 (en) 2019-09-19
ECSP18000887A (es) 2018-03-31
PH12017502207A1 (en) 2018-06-11
US10287343B2 (en) 2019-05-14
US11732034B2 (en) 2023-08-22
US10889640B2 (en) 2021-01-12
KR20250027278A (ko) 2025-02-25
ZA201800027B (en) 2019-06-26
EP3319983A1 (fr) 2018-05-16
UY36773A (es) 2017-01-31
ES3060419T3 (en) 2026-03-26
AU2016289755A1 (en) 2018-01-04
MY193677A (en) 2022-10-25
EP3319983C0 (fr) 2026-01-28
PE20180481A1 (es) 2018-03-07
CN107849104A (zh) 2018-03-27
NZ738058A (en) 2021-07-30
SMT202600068T1 (it) 2026-03-09
RS67937B1 (sr) 2026-04-30
KR20180025962A (ko) 2018-03-09
TN2017000539A1 (en) 2019-04-12
TWI745295B (zh) 2021-11-11
US20180201666A1 (en) 2018-07-19
JP2018524001A (ja) 2018-08-30
US20210115121A1 (en) 2021-04-22
CA2991451A1 (fr) 2017-01-12
UA124616C2 (uk) 2021-10-20
EA037092B1 (ru) 2021-02-04
MA42377A (fr) 2018-05-16
TW201713689A (zh) 2017-04-16
EP3319983B1 (fr) 2026-01-28
HRP20260348T1 (hr) 2026-04-24
MX2017015817A (es) 2018-04-10
IL256685B (en) 2022-02-01
JP7413448B2 (ja) 2024-01-15
EP4729538A2 (fr) 2026-04-22
HK1246804A1 (zh) 2018-09-14
MD3319983T2 (ro) 2026-03-31
CO2017012971A2 (es) 2018-03-09
AR105267A1 (es) 2017-09-20
JP2022141689A (ja) 2022-09-29
JP6630426B2 (ja) 2020-01-15
WO2017005734A1 (fr) 2017-01-12
PH12017502207B1 (en) 2022-08-10
CL2018000043A1 (es) 2018-05-18
BR112017028102A2 (en) 2018-09-04
AU2016289755B2 (en) 2020-12-03
EA201890172A1 (ru) 2018-10-31
IL256685A (en) 2018-03-29
US20230416350A1 (en) 2023-12-28
JP7100008B2 (ja) 2022-07-12
AU2016289755C1 (en) 2021-08-19
JP2020055849A (ja) 2020-04-09
CN107849104B (zh) 2021-08-27
SG10202010735PA (en) 2020-11-27
KR102770650B1 (ko) 2025-02-19

Similar Documents

Publication Publication Date Title
MA41669A1 (fr) Anticorps se liant a tau
MA51734A (fr) Anticorps se liant à gprc5d
ECSP18000887A (es) Anticuerpos de unión a tau
MA43186B1 (fr) Anticorps se liant spécifiquement à pd-1 et leurs utilisations
EP3512549A4 (fr) Anticorps se liant à cd3
MA40682A (fr) Anticorps anti-ox40 et procédés d'utilisation correspondants
BR112015022260A8 (pt) imunoterapia com tau
MA43018B1 (fr) Anticorps anti-pd1 et procédés d'utilisation
CU20190006A7 (es) Composiciones para inhibir masp-3
EP3408400A4 (fr) Protéines de liaison à l'antigène se liant à pd-l1
EP3331564A4 (fr) Constructions de liaison d'antigène se liant à des molécules cibles
BR112016029579A2 (pt) anticorpos e fragmentos de ligação ao antígeno que se ligam especificamente à proteína tau associada a microtúbulos
MA40576A (fr) Anticorps et immunoconjugués anti-her2
MX388164B (es) Anticuerpos y fragmentos anti-vista
BR112018072394A2 (pt) anticorpos que reconhecem a tau
MA44072A (fr) Anticorps se liant spécifiquement à hla-dr et leurs utilisations
MA39248B1 (fr) Anticorps anti-jagged1 et procédés d'utilisation correspondants
MA49289A (fr) Anticorps se liant à steap-1
MA51302A (fr) Anticorps se liant à hla-a2/wt1
MA39090B2 (fr) Anticorps anti-ccl17
EP3514177A4 (fr) Anticorps se liant spécifiquement à pd -1 et fragment fonctionnel de celui-ci
EP3514176A4 (fr) Anticorps se liant spécifiquement à il -17 a et fragment fonctionnel de celui-ci
EP3297662A4 (fr) Anticorps se liant à des protéines axl
MA43715A (fr) Anticorps anti-tnf et fragments fonctionnels correspondants
EP3766900A4 (fr) Anticorps se liant spécifiquement à folr1 et utilisations associées