MA41669A1 - Anticorps se liant a tau - Google Patents

Anticorps se liant a tau

Info

Publication number
MA41669A1
MA41669A1 MA41669A MA41669A MA41669A1 MA 41669 A1 MA41669 A1 MA 41669A1 MA 41669 A MA41669 A MA 41669A MA 41669 A MA41669 A MA 41669A MA 41669 A1 MA41669 A1 MA 41669A1
Authority
MA
Morocco
Prior art keywords
tau
antibodies binding
binding
antibodies
relates
Prior art date
Application number
MA41669A
Other languages
English (en)
Inventor
Kerry Louise Tyson
Terence Seward Baker
Georges Mairet-Coello
Patrick Downey
Jean-Philippe Courade
David Edward Ormonde Knight
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of MA41669A1 publication Critical patent/MA41669A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des anticorps se liant à tau et des fragments de liaison de ceux-ci.
MA41669A 2015-07-06 2016-07-05 Anticorps se liant a tau MA41669A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15175519 2015-07-06
PCT/EP2016/065809 WO2017005732A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau

Publications (1)

Publication Number Publication Date
MA41669A1 true MA41669A1 (fr) 2018-05-31

Family

ID=53524638

Family Applications (2)

Application Number Title Priority Date Filing Date
MA042380A MA42380A (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau
MA41669A MA41669A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant a tau

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA042380A MA42380A (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau

Country Status (23)

Country Link
US (4) US10344081B2 (fr)
EP (1) EP3319984B1 (fr)
JP (1) JP6937289B2 (fr)
KR (1) KR102742965B1 (fr)
CN (1) CN107849105B (fr)
AR (1) AR105266A1 (fr)
AU (1) AU2016289753C1 (fr)
CA (1) CA2991264C (fr)
CL (1) CL2018000042A1 (fr)
CO (1) CO2017012974A2 (fr)
EA (1) EA036821B1 (fr)
EC (1) ECSP18000844A (fr)
ES (1) ES3064846T3 (fr)
IL (1) IL256687B (fr)
MA (2) MA42380A (fr)
MX (1) MX2017015908A (fr)
PE (1) PE20180499A1 (fr)
PH (1) PH12017502180A1 (fr)
TN (1) TN2017000543A1 (fr)
TW (1) TWI748954B (fr)
UY (1) UY36774A (fr)
WO (1) WO2017005732A1 (fr)
ZA (1) ZA201708128B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014165271A2 (fr) 2013-03-13 2014-10-09 Neotope Biosciences Limited Immunothérapie contre tau
NZ775762A (en) 2015-06-05 2025-02-28 Genentech Inc Anti-tau antibodies and methods of use
SG10202010735PA (en) 2015-07-06 2020-11-27 UCB Biopharma SRL Tau-binding antibodies
CA2991264C (fr) 2015-07-06 2023-10-10 Ucb Biopharma Sprl Anticorps se liant a tau
EP3452507B1 (fr) 2016-05-02 2022-10-19 Prothena Biosciences Limited Immunothérapie anti-tau
MX2018013384A (es) 2016-05-02 2019-02-28 Prothena Biosciences Ltd Anticuerpos que reconocen tau.
EP3551220B1 (fr) 2016-12-07 2025-01-29 Genentech, Inc. Anticorps anti-tau et ses utilisation
EP3551655A2 (fr) 2016-12-07 2019-10-16 Genentech, Inc. Anticorps anti-tau et méthodes d'utilisation de ces derniers
EP3824906A1 (fr) 2016-12-21 2021-05-26 Amgen Inc. Formulations d'anticorps anti-tnf alpha
US20200095327A1 (en) * 2017-02-08 2020-03-26 Dragonfly Therapeutics, Inc. Antibody heavy chain variable domains targeting the nkg2d receptor
CN110944651A (zh) 2017-02-08 2020-03-31 蜻蜓疗法股份有限公司 用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途
CA3053379A1 (fr) 2017-02-17 2018-08-23 Denali Therapeutics Inc. Anticorps anti-tau et leurs procedes d'utilisation
EP4273258A3 (fr) 2017-02-20 2024-01-17 Dragonfly Therapeutics, Inc. Protéines se liant à her2, nkg2d et cd16
JP2018139530A (ja) 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
SG11201910066QA (en) 2017-05-02 2019-11-28 Prothena Biosciences Ltd Antibodies recognizing tau
JP6851549B2 (ja) 2017-10-16 2021-03-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗タウ抗体及びその使用
CA3090244A1 (fr) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Domaines variables d'anticorps ciblant le recepteur nkg2d
MX2020008333A (es) 2018-02-08 2020-09-21 Dragonfly Therapeutics Inc Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales.
CN112119093A (zh) 2018-02-20 2020-12-22 蜻蜓治疗公司 结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
CA3108427A1 (fr) 2018-08-08 2020-02-13 Dragonfly Therapeutics, Inc. Proteines de liaison multi-specifiques se liant a bcma, nkg2d et cd16, et methodes d'utilisation
CN113164570B (zh) 2018-08-08 2024-05-14 蜻蜓疗法股份有限公司 结合nkg2d、cd16和肿瘤相关抗原的蛋白质
WO2020120644A1 (fr) * 2018-12-13 2020-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Nouvel anticorps à domaine unique d'épitope dirigé contre tau svqivykpv
TWI859197B (zh) 2019-03-03 2024-10-21 愛爾蘭商普羅帝納生物科學公司 識別ｔａｕ之抗體
PE20230385A1 (es) * 2020-04-08 2023-03-06 Janssen Biotech Inc Anticuerpos anti-phf-tau y usos de estos
AU2021268340A1 (en) 2020-05-06 2022-12-08 Dragonfly Therapeutics, Inc. Proteins binding NKG2D, CD16 and CLEC12A
CN116723856A (zh) 2020-06-25 2023-09-08 默沙东有限责任公司 靶向丝氨酸413处磷酸化的tau的高亲和力抗体
US20240101654A1 (en) * 2020-12-29 2024-03-28 Neurimmune Ag Human anti-tau antibodies
EP4301774A4 (fr) 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc Méthodes de traitement du cancer à l'aide de protéines de liaison multi-spécifiques qui se lient à nkg2d, à cd16 et à un antigène associé à une tumeur
WO2023092004A1 (fr) 2021-11-17 2023-05-25 Voyager Therapeutics, Inc. Compositions et méthodes pour le traitement de troubles liés à tau
JP2025535203A (ja) 2022-09-15 2025-10-23 ボイジャー セラピューティクス インコーポレイテッド タウ結合化合物
WO2025122634A1 (fr) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions et méthodes pour le traitement de troubles liés à la protéine tau
WO2025147472A1 (fr) * 2024-01-02 2025-07-10 Phanes Therapeutics, Inc. Anticorps anti-611-ctf p95her2 et leurs utilisations
WO2025196217A1 (fr) 2024-03-21 2025-09-25 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau
WO2026057816A1 (fr) 2024-09-13 2026-03-19 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau
WO2026102093A1 (fr) 2024-11-07 2026-05-15 Voyager Therapeutics, Inc. Compositions et procédés pour le traitement de troubles liés à la protéine tau

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
ATE154642T1 (de) 1991-10-25 1997-07-15 Innogenetics Nv Monoklonale antikörper gegen das mikrotubulusassoziierte protein tau.
US7408027B1 (en) 1991-12-06 2008-08-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften Tools for the diagnosis and treatment of Alzheimer's disease
US6010913A (en) 1992-12-14 2000-01-04 N.V. Innogenetics S.A. Isolated human tau peptide
ATE335007T1 (de) 1993-12-21 2006-08-15 Innogenetics Nv Monoklonale antikörper gegen phf-tau, hybridomen die diese ausscheiden, antigenerkennung durch diesen antikörper und deren verwendungen
CA2195672A1 (fr) 1994-07-29 1996-02-15 Eugeen Vanmechelen Anticorps monoclonaux specifiques d'un epitope d'une sous-classe ou forme particuliere de tau phosphorylee, hybridomes les secretant, reconnaissance par les antigenes de ces anticorps et leurs applications
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
PT1644412E (pt) 2003-07-01 2015-12-23 Ucb Biopharma Sprl Fragmentos de anticorpos fab modificados
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
CN1721437A (zh) * 2004-07-13 2006-01-18 中南大学 一种与Tau蛋白相关的多肽抗原及抗体
KR20140053410A (ko) 2005-08-19 2014-05-07 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
NZ568012A (en) 2005-12-12 2012-07-27 Ac Immune Sa A beta 1-42 specific monoclonal antibodies with therapeutic properties
GB0614780D0 (en) 2006-07-25 2006-09-06 Ucb Sa Biological products
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
EP2535350B1 (fr) 2007-09-26 2018-01-24 UCB Biopharma SPRL Fusions d'anticorps à double spécificité
BRPI0822556B1 (pt) * 2008-03-26 2022-03-03 Epitomics, Inc Anticorpo monoclonal anti-vegf e composição farmacêutica
CN101307108B (zh) * 2008-06-25 2012-04-04 南京川博生物技术有限公司 抗磷酸化Tau蛋白抗体及其在AD症异常磷酸化Tau蛋白水平测定上的用途
US10407513B2 (en) 2008-09-26 2019-09-10 Ucb Biopharma Sprl Biological products
UA107571C2 (xx) 2009-04-03 2015-01-26 Фармацевтична композиція
US8609097B2 (en) * 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
EP4218794A3 (fr) 2009-06-10 2023-09-13 New York University Ciblage immunologique de protéines tau pathologiques
CN102596236B (zh) 2009-07-30 2015-06-24 辉瑞疫苗有限责任公司 抗原性Tau肽及其用途
WO2011030107A1 (fr) 2009-09-10 2011-03-17 Ucb Pharma S.A. Anticorps multivalents
LT2627672T (lt) 2010-10-11 2018-12-10 Biogen International Neuroscience Gmbh Žmogaus antikūnai prieš tau baltymą
WO2012106363A2 (fr) 2011-01-31 2012-08-09 Intellect Neurosciences Inc. Traitement de tauopathies
GB201112056D0 (en) 2011-07-14 2011-08-31 Univ Leuven Kath Antibodies
EP3275461A1 (fr) 2011-09-19 2018-01-31 Axon Neuroscience SE Thérapie protéique et diagnostic d'une pathologie à médiation par tau dans la maladie d'alzheimer
JP6358953B2 (ja) * 2011-10-07 2018-07-18 エーシー イミューン エス．エー． タウを認識するホスホ特異的抗体
JP6411214B2 (ja) 2011-11-11 2018-10-24 ユーシービー バイオファルマ エスピーアールエル アルブミン結合抗体及びその結合断片
CA2859665C (fr) 2011-12-20 2024-05-21 Janssen Biotech, Inc. Anticorps anti-phf-tau et leurs utilisations
CA2869438C (fr) 2012-04-05 2021-08-17 Ac Immune S.A. Anticorps tau humanise
EP2870176A4 (fr) 2012-07-03 2016-09-28 Univ Washington Anticorps dirigés contre tau
WO2014016737A1 (fr) 2012-07-24 2014-01-30 Pfizer Inc. Nouveaux anticorps monoclonaux de poulet dirigés contre la protéine tau phosphorylée humaine et leurs utilisations
EP2885010B1 (fr) * 2012-08-16 2020-01-01 Ipierian, Inc. Méthodes de traitement d'une tauopathie
JP6284548B2 (ja) 2012-12-21 2018-02-28 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． ヒト抗タウ抗体
WO2014165271A2 (fr) 2013-03-13 2014-10-09 Neotope Biosciences Limited Immunothérapie contre tau
MX374811B (es) 2013-03-15 2025-03-06 Ac Immune Sa Anticuerpos anti-tau y métodos de uso.
CR20160270A (es) 2013-12-20 2016-09-05 Hoffmann La Roche ANTICUERPOS ANTI-TAU (pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN
CA2874083C (fr) * 2014-12-05 2024-01-02 Universite Laval Polypeptides liant le tdp-43 utiles pour le traitement de maladies neurodegeneratives
AR103713A1 (es) 2015-02-26 2017-05-31 Lilly Co Eli Anticuerpos contra tau y sus usos
NZ775762A (en) 2015-06-05 2025-02-28 Genentech Inc Anti-tau antibodies and methods of use
CA2991264C (fr) 2015-07-06 2023-10-10 Ucb Biopharma Sprl Anticorps se liant a tau
SG10202010735PA (en) 2015-07-06 2020-11-27 UCB Biopharma SRL Tau-binding antibodies
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها

Also Published As

Publication number Publication date
ES3064846T3 (en) 2026-04-29
MA42380A (fr) 2018-05-16
PH12017502180A1 (en) 2018-05-28
US10906966B2 (en) 2021-02-02
PE20180499A1 (es) 2018-03-09
AU2016289753A1 (en) 2017-12-14
AR105266A1 (es) 2017-09-20
ECSP18000844A (es) 2018-03-31
EP3319984C0 (fr) 2026-03-11
TN2017000543A1 (en) 2019-04-12
ZA201708128B (en) 2019-05-29
US20190375829A1 (en) 2019-12-12
US11746145B2 (en) 2023-09-05
KR102742965B1 (ko) 2024-12-13
AU2016289753B2 (en) 2020-11-26
CO2017012974A2 (es) 2018-03-09
EA201890169A1 (ru) 2018-10-31
EA036821B1 (ru) 2020-12-23
NZ737843A (en) 2024-05-31
CA2991264C (fr) 2023-10-10
US20230331833A1 (en) 2023-10-19
CA2991264A1 (fr) 2017-01-12
US10344081B2 (en) 2019-07-09
KR20180027566A (ko) 2018-03-14
US20210139574A1 (en) 2021-05-13
CL2018000042A1 (es) 2018-06-01
BR112017028101A2 (en) 2018-09-04
AU2016289753C1 (en) 2021-08-05
CN107849105B (zh) 2021-09-17
IL256687B (en) 2022-02-01
US20180194832A1 (en) 2018-07-12
MX2017015908A (es) 2018-03-15
JP2018519833A (ja) 2018-07-26
WO2017005732A1 (fr) 2017-01-12
UY36774A (es) 2017-01-31
EP3319984B1 (fr) 2026-03-11
IL256687A (en) 2018-03-29
TW201713688A (zh) 2017-04-16
CN107849105A (zh) 2018-03-27
JP6937289B2 (ja) 2021-09-22
EP3319984A1 (fr) 2018-05-16
TWI748954B (zh) 2021-12-11

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