MA41974A - Composés de pyrazolo- et triazolo-pyrimidine antiviraux du virus respiratoire syncytial (vrs) - Google Patents

Composés de pyrazolo- et triazolo-pyrimidine antiviraux du virus respiratoire syncytial (vrs)

Info

Publication number
MA41974A
MA41974A MA041974A MA41974A MA41974A MA 41974 A MA41974 A MA 41974A MA 041974 A MA041974 A MA 041974A MA 41974 A MA41974 A MA 41974A MA 41974 A MA41974 A MA 41974A
Authority
MA
Morocco
Prior art keywords
triazolo
pyrazolo
rsv
antiviral
respiratory syncytial
Prior art date
Application number
MA041974A
Other languages
English (en)
Inventor
Vadim Bichko
Jérôme Émile Georges Guillemont
Anil Koul
David Francis Alain Lançois
Delphine Yvonne Raymonde Lardeau
Antoine Benjamin Michaut
Pierre Jean-Marie Bernard Raboisson
Boris Rogovoy
Dirk André Emmy Roymans
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of MA41974A publication Critical patent/MA41974A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA041974A 2015-04-28 2016-04-27 Composés de pyrazolo- et triazolo-pyrimidine antiviraux du virus respiratoire syncytial (vrs) MA41974A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562153753P 2015-04-28 2015-04-28
US201562204390P 2015-08-12 2015-08-12

Publications (1)

Publication Number Publication Date
MA41974A true MA41974A (fr) 2018-03-07

Family

ID=55860847

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041974A MA41974A (fr) 2015-04-28 2016-04-27 Composés de pyrazolo- et triazolo-pyrimidine antiviraux du virus respiratoire syncytial (vrs)

Country Status (29)

Country Link
US (3) US10208048B2 (fr)
EP (1) EP3288942B1 (fr)
JP (1) JP6698693B2 (fr)
KR (1) KR102538565B1 (fr)
CN (1) CN107531715B (fr)
AU (1) AU2016254700B2 (fr)
BR (1) BR112017023263B1 (fr)
CA (1) CA2981404C (fr)
CL (1) CL2017002709A1 (fr)
CY (1) CY1125329T1 (fr)
DK (1) DK3288942T3 (fr)
EA (1) EA035689B1 (fr)
ES (1) ES2905550T3 (fr)
HR (1) HRP20211728T1 (fr)
HU (1) HUE057626T2 (fr)
IL (1) IL254750B (fr)
JO (1) JO3637B1 (fr)
LT (1) LT3288942T (fr)
MA (1) MA41974A (fr)
MX (1) MX369040B (fr)
PH (1) PH12017501958B1 (fr)
PL (1) PL3288942T3 (fr)
PT (1) PT3288942T (fr)
SG (1) SG11201708786SA (fr)
SI (1) SI3288942T1 (fr)
TW (1) TWI703146B (fr)
UA (1) UA120448C2 (fr)
WO (1) WO2016174079A1 (fr)
ZA (1) ZA201707320B (fr)

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JO3637B1 (ar) * 2015-04-28 2020-08-27 Janssen Sciences Ireland Uc مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv
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Also Published As

Publication number Publication date
HK1248230A1 (zh) 2018-10-12
US20180105529A1 (en) 2018-04-19
IL254750A0 (en) 2017-11-30
ZA201707320B (en) 2020-08-26
US10208048B2 (en) 2019-02-19
JO3637B1 (ar) 2020-08-27
KR102538565B1 (ko) 2023-05-30
BR112017023263A2 (pt) 2018-08-07
EP3288942A1 (fr) 2018-03-07
WO2016174079A1 (fr) 2016-11-03
LT3288942T (lt) 2021-12-10
PT3288942T (pt) 2021-12-17
MX369040B (es) 2019-10-25
PL3288942T3 (pl) 2022-02-21
JP2018514544A (ja) 2018-06-07
US10611769B2 (en) 2020-04-07
AU2016254700A1 (en) 2017-10-19
EA035689B1 (ru) 2020-07-27
CA2981404A1 (fr) 2016-11-03
PH12017501958A1 (en) 2018-03-26
CL2017002709A1 (es) 2018-04-20
TW201708227A (zh) 2017-03-01
CY1125329T1 (el) 2024-02-16
DK3288942T3 (da) 2022-01-17
CN107531715B (zh) 2021-03-30
BR112017023263B1 (pt) 2023-04-11
AU2016254700B2 (en) 2020-01-02
HUE057626T2 (hu) 2022-05-28
EP3288942B1 (fr) 2021-10-27
SI3288942T1 (sl) 2022-01-31
US11084826B2 (en) 2021-08-10
ES2905550T3 (es) 2022-04-11
US20190248793A1 (en) 2019-08-15
IL254750B (en) 2020-07-30
TWI703146B (zh) 2020-09-01
UA120448C2 (uk) 2019-12-10
US20200223855A1 (en) 2020-07-16
MX2017013884A (es) 2018-03-16
KR20170139122A (ko) 2017-12-18
EA201792370A1 (ru) 2018-02-28
SG11201708786SA (en) 2017-11-29
PH12017501958B1 (en) 2018-03-26
JP6698693B2 (ja) 2020-05-27
CA2981404C (fr) 2023-09-19
HRP20211728T1 (hr) 2022-02-18
CN107531715A (zh) 2018-01-02

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