MA42055A - Composés antimicrobiens et procédés de fabrication et d'utilisation de ceux-ci - Google Patents

Composés antimicrobiens et procédés de fabrication et d'utilisation de ceux-ci

Info

Publication number
MA42055A
MA42055A MA042055A MA42055A MA42055A MA 42055 A MA42055 A MA 42055A MA 042055 A MA042055 A MA 042055A MA 42055 A MA42055 A MA 42055A MA 42055 A MA42055 A MA 42055A
Authority
MA
Morocco
Prior art keywords
processes
manufacturing
same
antimicrobial compounds
antimicrobial
Prior art date
Application number
MA042055A
Other languages
English (en)
Inventor
Ashoke Bhattacharjee
Somenath Chowdhury
Erin M Duffy
Zoltan F Kanyo
Wan LAU
Vinay Thakur
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Publication of MA42055A publication Critical patent/MA42055A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA042055A 2015-03-11 2016-03-11 Composés antimicrobiens et procédés de fabrication et d'utilisation de ceux-ci MA42055A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562131751P 2015-03-11 2015-03-11

Publications (1)

Publication Number Publication Date
MA42055A true MA42055A (fr) 2018-03-14

Family

ID=56879869

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042055A MA42055A (fr) 2015-03-11 2016-03-11 Composés antimicrobiens et procédés de fabrication et d'utilisation de ceux-ci

Country Status (16)

Country Link
US (1) US10947237B2 (fr)
EP (1) EP3268370A4 (fr)
JP (1) JP2018507881A (fr)
KR (1) KR20180015114A (fr)
CN (1) CN107922418A (fr)
AU (1) AU2016228584A1 (fr)
BR (1) BR112017019349A2 (fr)
CA (1) CA2979342A1 (fr)
EA (1) EA201792006A1 (fr)
HK (1) HK1249758A1 (fr)
IL (1) IL254398A0 (fr)
MA (1) MA42055A (fr)
MX (1) MX2017011616A (fr)
PH (1) PH12017501646A1 (fr)
SG (1) SG11201707346RA (fr)
WO (1) WO2016145417A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6274723B2 (ja) 2009-10-16 2018-02-07 メリンタ セラピューティクス,インコーポレイテッド 抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
MX2016002975A (es) 2013-09-09 2016-10-21 Melinta Therapeutics Inc Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos.
US20180141897A1 (en) 2014-12-08 2018-05-24 The Research Foundation For The State University Of New York Anti-fungals targeting the synthesis of fungal shingolipids
US11098047B2 (en) * 2016-05-06 2021-08-24 BioVersys AG Antimicrobials and methods of making and using same
US10934295B2 (en) * 2016-05-06 2021-03-02 BioVersys AG Antimicrobials and methods of making and using same
JP7217700B2 (ja) 2016-09-13 2023-02-03 アラーガン、インコーポレイテッド 安定化非タンパク質クロストリジウム毒素組成物
EP3638649A4 (fr) 2017-06-16 2021-03-17 The Research Foundation for The State University of New York Composés anti-fongiques ciblant la synthèse de shingolipides fongiques
EP3642205A1 (fr) * 2017-06-19 2020-04-29 Erin M. Duffy Agents antimicrobiens et leurs procédés de préparation et d'utilisation
WO2019164880A1 (fr) * 2018-02-21 2019-08-29 Duffy Erin M Antimicrobiens et leurs procédés de fabrication et d'utilisation
US11760701B2 (en) 2018-02-27 2023-09-19 The Research Foundation For The State University Of New Yrok Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
DK3773201T3 (da) * 2018-03-28 2024-10-21 Dexcom Inc Sensorkabelstøtteindretning omfattende mekaniske konnektorer
US20210253589A1 (en) * 2018-06-06 2021-08-19 BioVersys AG Aminomethylamidine and methylamidine antimicrobial compounds
WO2019234508A1 (fr) * 2018-06-06 2019-12-12 BioVersys AG Agents de biodéfense
CA3126815A1 (fr) * 2019-01-16 2020-07-23 Curza Global, Llc Composes antimicrobiens et procedes
JP2022518230A (ja) * 2019-01-16 2022-03-14 カーザ グローバル, エルエルシー 抗菌化合物及び方法
CA3158103A1 (fr) * 2019-11-13 2021-05-20 Curza Global, Llc Composes antimicrobiens et procedes
EP4444726A4 (fr) * 2021-12-06 2025-11-26 Pretzel Therapeutics Inc Inhibiteurs de lonp1, utilisations et méthodes

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2624731A (en) 1953-01-06 S-phenylpyrimidkn e x derivativesx
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US3673184A (en) 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
US4361557A (en) 1980-01-28 1982-11-30 Schering Corporation 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
EP0067610A1 (fr) 1981-06-16 1982-12-22 Beecham Group Plc Pénicillines, un procédé pour leur préparation et compositions les contenant
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
ZA835684B (en) 1982-08-27 1985-03-27 Roussel Uclaf Imidazo(1,2-a)pyrimidines
US5332835A (en) 1984-02-03 1994-07-26 Zambon S.P.A. Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process
JPS6191184A (ja) 1984-10-08 1986-05-09 Morishita Seiyaku Kk 2−アニリノ−5−(1h−テトラゾ−ル−5−イル)ピリミジン−4(3h)−オン誘導体
DE3446812A1 (de) 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
JP2873340B2 (ja) 1988-04-29 1999-03-24 武田薬品工業株式会社 抗生物質tan―1057,その製造法および用途
JP2549931B2 (ja) 1990-01-12 1996-10-30 株式会社大塚製薬工場 ピリミドベンズイミダゾール誘導体
JP2991382B2 (ja) 1990-07-18 1999-12-20 大日本製薬株式会社 縮合三環式化合物およびその塩
JP2811230B2 (ja) 1990-10-17 1998-10-15 コニカ株式会社 新規な写真用カプラー
US5208141A (en) 1990-10-09 1993-05-04 Konica Corporation Silver halide color photographic light-sensitive material
US5958930A (en) 1991-04-08 1999-09-28 Duquesne University Of The Holy Ghost Pyrrolo pyrimidine and furo pyrimidine derivatives
US6451968B1 (en) 1991-05-24 2002-09-17 Isis Pharmaceuticals, Inc. Peptide nucleic acids
US5766855A (en) 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
US5434257A (en) 1992-06-01 1995-07-18 Gilead Sciences, Inc. Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages
US5646163A (en) 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
RU2139862C1 (ru) 1993-05-12 1999-10-20 Е.И. Дю Пон де Немурс энд Компани Замещенные 4(3н)-хиназолиноны, обладающие фунгицидными свойствами, композиции на их основе и способы борьбы с мучнистой росой
US5502177A (en) 1993-09-17 1996-03-26 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
TW424090B (en) 1995-08-18 2001-03-01 Nat Science Council Pyrimidines as folate antimetabolites with selective activity against human brain cancer
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
US7282327B2 (en) 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
GB9708611D0 (en) 1997-04-28 1997-06-18 Univ Cardiff Chemical compounds
EP1003727A1 (fr) 1997-08-07 2000-05-31 Research Corporation Technologies Antibiotique contre une bacterie resistante a la methicilline
US6028183A (en) 1997-11-07 2000-02-22 Gilead Sciences, Inc. Pyrimidine derivatives and oligonucleotides containing same
AU1292899A (en) 1997-11-07 1999-05-31 Isis Pharmaceuticals, Inc. Pyrimidine derivatives for labeled binding partners
DE19838998A1 (de) 1998-08-27 2000-03-09 Bayer Ag Neue Naturstoffderivate
SE9903894D0 (sv) 1999-10-28 1999-10-28 New Pharma Research Ab Novel compounds
EP1113008A1 (fr) 1999-12-29 2001-07-04 Pfizer Products Inc. Derives de 4-oxo-2-ureido-1,4,5,6-tetrahydropyrimidine utiles comme agents antibacteriens et antiprotozoaires
KR100358083B1 (ko) 2000-02-17 2002-10-25 에스케이케미칼주식회사 피롤로피리미디논 유도체와 이의 제조방법, 그리고 이의용도
KR20090089922A (ko) 2000-10-18 2009-08-24 파마셋 인코포레이티드 바이러스 감염 및 비정상적인 세포 증식의 치료를 위한 변형된 뉴클레오시드
DE10061541A1 (de) 2000-12-11 2002-06-20 Bayer Ag Arylamino-Dihydropyrimidinone
DE10061537A1 (de) 2000-12-11 2002-06-20 Bayer Ag beta-Alanin-Derivate
DE10061538A1 (de) 2000-12-11 2002-06-20 Bayer Ag Ureido-Dihydropyrimidinone
DE10061542A1 (de) 2000-12-11 2002-06-13 Bayer Ag Alkanoylamino-pyrimidine
ATE304539T1 (de) 2000-12-14 2005-09-15 Procter & Gamble Antimikrobielle chinolone
US6900215B2 (en) 2000-12-15 2005-05-31 Merck Sharp & Dohme Ltd. Imidazo-pyrimidine derivatives as ligands for gaba receptors
WO2002061110A2 (fr) 2001-01-29 2002-08-08 Bio-Rad Laboratories, Inc. Derives d'acide nucleique
TWI248936B (en) 2001-03-21 2006-02-11 Merck Sharp & Dohme Imidazo-pyrimidine derivatives as ligands for GABA receptors
US20030207804A1 (en) 2001-05-25 2003-11-06 Muthiah Manoharan Modified peptide nucleic acids
JP2005504020A (ja) 2001-07-03 2005-02-10 アイシス・ファーマシューティカルス・インコーポレーテッド ヌクレアーゼ耐性キメラオリゴヌクレオチド
US20030158403A1 (en) 2001-07-03 2003-08-21 Isis Pharmaceuticals, Inc. Nuclease resistant chimeric oligonucleotides
DE10133277A1 (de) 2001-07-09 2003-01-23 Bayer Ag ß-Alanin-Derivate
DE10141271A1 (de) 2001-08-23 2003-03-06 Bayer Ag Neue Tetrahydro-1,3,5-triazin-2-on-Derivate und ihre Verwendung
JP4306206B2 (ja) 2001-09-04 2009-07-29 住友化学株式会社 イミダゾ[1,2−a]ピリミジン、その用途およびその製造中間体
DE10208256A1 (de) 2002-02-26 2003-09-04 Bayer Ag Piperidinouracile
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
AU2003249503A1 (en) 2002-03-08 2003-09-29 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
PA8595001A1 (es) 2003-03-04 2004-09-28 Pfizer Prod Inc Nuevos compuestos heteroaromaticos condensados que son inhibidores del factor de crecimiento transforante (tgf)
WO2004080466A1 (fr) 2003-03-07 2004-09-23 Ribapharm Inc. Analogues de la cytidine et methodes d'utilisation
JP2007500160A (ja) 2003-07-30 2007-01-11 ラボラトリオス・エセ・ア・エレ・ベ・ア・テ・ソシエダッド・アノニマ 癌の予防および治療のための置換イミダゾピリミジン
KR20060069836A (ko) 2003-08-12 2006-06-22 아칠리온 파르마세우티칼스 인코포레이티드 항-감염제로서의 이소티아졸로퀴놀론 및 관련 화합물
CN1871240B (zh) 2003-08-26 2012-11-07 帝人制药株式会社 吡咯并嘧啶酮衍生物
TW200524880A (en) 2003-10-21 2005-08-01 Sankyo Co Pyrimidine compounds
WO2006002627A2 (fr) 2004-06-30 2006-01-12 Zgene A/S Enzymes de desoxycytidine du poulet et de desoxyadenosine kinase et leur utilisation
ES2352799T3 (es) 2005-07-27 2011-02-23 Achillion Pharmaceuticals, Inc. 8-metoxi-9h-isotiazolo[5,4-b]quinolina-3,4-dionas y compuestos relacionados.
WO2007058580A1 (fr) 2005-11-15 2007-05-24 Astrazeneca Ab Nouveaux derives de 2-aminopyrimidinone et leur utilisation
NZ544187A (en) 2005-12-15 2008-07-31 Ind Res Ltd Deazapurine analogs of 1'-aza-l-nucleosides
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
ATE496766T1 (de) 2006-03-03 2011-02-15 Fujifilm Corp Härtbare zusammensetzung, tintenzusammensetzung, tintenstrahlaufzeichnungsverfahren und flachdruckplatte
JP2007270087A (ja) 2006-03-31 2007-10-18 Fujifilm Corp 硬化性組成物、インク組成物、インクジェット記録方法、印刷物、平版印刷版の製造方法、及び平版印刷版
WO2007101871A1 (fr) 2006-03-08 2007-09-13 Basf Se Imidazolopyrimidines substituées, procédés de production associés et leur utilisation pour lutter contre des champignons nuisibles, et agents les contenant
KR20080003599A (ko) 2006-07-03 2008-01-08 에스케이케미칼주식회사 피롤로피리미디논 유도체의 겐티세이트 염 및 이의제조방법
CA2666696C (fr) 2006-07-03 2013-01-15 Sk Chemicals Co., Ltd. Sels de derives de pyrrolopyrimidinone et methode d'obtention
WO2008082440A2 (fr) 2006-08-25 2008-07-10 Emory University Analogues de nucléoside fluorescents
ES2362805T3 (es) 2006-09-07 2011-07-13 Industrial Research Limited Inhibidores aminoacíclicos de nucleósido fosforilasas e hidrolasas.
EP1964841A1 (fr) 2007-02-28 2008-09-03 sanofi-aventis Imidazo[1,2-a]azine et son utilisation en tant que produit pharmaceutique
WO2008106224A1 (fr) 2007-02-28 2008-09-04 Rib-X Pharmaceuticals, Inc. Composés macrolides et procédés de fabrication et d'utilisation de ceux-ci
AU2008223348A1 (en) 2007-03-07 2008-09-12 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors containing a heterocyclic moiety
JP2008222557A (ja) 2007-03-08 2008-09-25 Kotobuki Seiyaku Kk ピロロ[3,2−d]ピリミジン誘導体及びこれを有効成分とする医薬組成物
KR20100022999A (ko) 2007-05-30 2010-03-03 쉐링-프라우 리미티드 플로르페니콜에 대한 중간체로서 유용한 옥사졸린-보호된 아미노디올 화합물의 제조방법
CA2691987C (fr) 2007-06-12 2016-08-16 Achaogen, Inc. Agents antibacteriens
CA2687217A1 (fr) 2007-06-13 2008-12-24 Northeastern University Composes antibiotiques
GB0724342D0 (en) 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
KR20090098710A (ko) 2008-03-14 2009-09-17 주식회사 씨티아이바이오 세포투과성과 핵산 결합력이 좋은 펩타이드 핵산 유도체
UY32395A (es) 2009-01-27 2010-08-31 Takeda Pharmaceutical Compuesto con anillo fusionado y su uso
US8975389B2 (en) 2009-03-02 2015-03-10 Alnylam Pharmaceuticals, Inc. Nucleic acid chemical modifications
WO2011017319A1 (fr) 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Méthodes de traitement de troubles associés à la polymérisation d'une protéine
US20120263646A1 (en) 2009-10-15 2012-10-18 Guerbet Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases
JP2013508299A (ja) 2009-10-16 2013-03-07 リブ−エックス ファーマシューティカルズ,インコーポレイテッド 抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
EP3406613A1 (fr) * 2009-10-16 2018-11-28 Melinta Therapeutics, Inc. Composés antimicrobiens et leurs procédés de fabrication et d'utilisation
JP6274723B2 (ja) 2009-10-16 2018-02-07 メリンタ セラピューティクス,インコーポレイテッド 抗微生物性化合物および抗微生物性化合物の製造方法および使用方法
NZ623384A (en) 2009-10-16 2016-06-24 Melinta Therapeutics Inc Antimicrobial compounds and methods of making and using the same
WO2012125832A2 (fr) 2011-03-15 2012-09-20 Rib-X Pharmaceuticals, Inc. Agents antimicrobiens
EP3404028A1 (fr) * 2011-04-15 2018-11-21 Melinta Therapeutics, Inc. Procédés de fabrication de composés antimicrobiens
US9937183B2 (en) * 2013-09-09 2018-04-10 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
MX2016002975A (es) * 2013-09-09 2016-10-21 Melinta Therapeutics Inc Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos.

Also Published As

Publication number Publication date
IL254398A0 (en) 2017-11-30
MX2017011616A (es) 2018-04-11
BR112017019349A2 (pt) 2018-06-05
AU2016228584A1 (en) 2017-10-05
SG11201707346RA (en) 2017-10-30
US20180065966A1 (en) 2018-03-08
CA2979342A1 (fr) 2016-09-15
EP3268370A4 (fr) 2018-08-22
WO2016145417A1 (fr) 2016-09-15
PH12017501646A1 (en) 2018-03-12
US10947237B2 (en) 2021-03-16
CN107922418A (zh) 2018-04-17
KR20180015114A (ko) 2018-02-12
EA201792006A1 (ru) 2018-04-30
JP2018507881A (ja) 2018-03-22
EP3268370A1 (fr) 2018-01-17
HK1249758A1 (zh) 2018-11-09

Similar Documents

Publication Publication Date Title
IL285461A (en) Processes and compounds
MA49858A (fr) Composés, compositions et procédés
MA50063A (fr) Composés, compositions et procédés
MA43802A (fr) Matières cellulosiques et procédés de fabrication et d'utilisation de celles-ci
MA43827A (fr) Composés di-nucléotides cycliques et leurs procédés d'utilisation
MA49861A (fr) Composés de benzoxazépine oxazolidinone et leurs procédés d'utilisation
EP3370715A4 (fr) Composés chimères de ciblage de protéolyse et procédés de préparation et d'utilisation de ceux-ci
EP3504213A4 (fr) Composés amino-pyrrolopyrimidinone et leurs procédés d'utilisation
EP3429635A4 (fr) Composés anti-crispr et leurs procédés d'utilisation
EP3341777A4 (fr) Miroirs à effet d'obliquité, procédés d'utilisation, et procédés de fabrication
EP3380101A4 (fr) Composés inhibiteurs d'eif4-a et procédés associés
EP3386550A4 (fr) Procédés et compositions pour la fabrication et l'utilisation d'acides nucléiques de guidage
EP3322666A4 (fr) Dispositifs à réactance accordable et leurs procédés de fabrication et d'utilisation
EP3645048A4 (fr) Anticorps multispécifiques et procédés de fabrication et d'utilisation associés
MA49560A (fr) Composés cétoniques bicycliques et leurs procédés d'utilisation
MA42612A (fr) Composés hétérocycliques fumagillol, et procédés correspondants de fabrication et d'utilisation
EP3352773A4 (fr) Formulations de bactériophages antibactériennes et protectrices, procédés de fabrication et d'utilisation associés
MA39915A (fr) Composés de pladiénolide pyridine et leurs procédés d'utilisation
SG11201707346RA (en) Antimicrobial compounds and methods of making and using the same
EP3468555A4 (fr) Composés antimicrobiens et leurs procédés d'utilisation
EP3307081A4 (fr) Compositions de lécithine et procédés de fabrication et d'utilisation de ces compositions de lécithine
EP3619193A4 (fr) Composés amino-aryl-benzamide et leurs procédés d'utilisation
EP3724933A4 (fr) Composés supraconducteurs et procédés de fabrication associés
EP3347003A4 (fr) Composés de thréonate et leurs procédés d'utilisation
EP3615502A4 (fr) Composés et procédés thérapeutiques