MA44006A - Inhibiteur pde1 - Google Patents

Inhibiteur pde1

Info

Publication number
MA44006A
MA44006A MA044006A MA44006A MA44006A MA 44006 A MA44006 A MA 44006A MA 044006 A MA044006 A MA 044006A MA 44006 A MA44006 A MA 44006A MA 44006 A MA44006 A MA 44006A
Authority
MA
Morocco
Prior art keywords
pde1 inhibitor
pde1
inhibitor
Prior art date
Application number
MA044006A
Other languages
English (en)
Inventor
Cynthia Darshini Jesudason
Mark David Rekhter
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA44006A publication Critical patent/MA44006A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA044006A 2016-02-12 2017-02-03 Inhibiteur pde1 MA44006A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662294329P 2016-02-12 2016-02-12

Publications (1)

Publication Number Publication Date
MA44006A true MA44006A (fr) 2021-04-14

Family

ID=58044210

Family Applications (1)

Application Number Title Priority Date Filing Date
MA044006A MA44006A (fr) 2016-02-12 2017-02-03 Inhibiteur pde1

Country Status (9)

Country Link
US (2) US9868741B2 (fr)
EP (1) EP3414249B1 (fr)
JP (1) JP6533875B2 (fr)
CN (1) CN108602835A (fr)
AR (1) AR107456A1 (fr)
ES (1) ES2879645T3 (fr)
MA (1) MA44006A (fr)
TW (1) TWI609870B (fr)
WO (1) WO2017139186A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201629064A (zh) 2014-10-10 2016-08-16 H 朗德貝克公司 作爲pde1抑制劑之三唑並吡酮
JO3627B1 (ar) 2015-04-30 2020-08-27 H Lundbeck As إيميدازو بيرازينونات على هيئة مثبطات pde1
TWI729109B (zh) 2016-04-12 2021-06-01 丹麥商H 朗德貝克公司 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮
JOP20170164A1 (ar) * 2016-08-25 2019-01-30 Lilly Co Eli مشتق ترايازولو بيرازينون مفيد كمثبط لـ pde1 بشري
CN109843884B (zh) 2016-10-18 2022-03-04 H.隆德贝克有限公司 作为pde1抑制剂的咪唑并吡嗪酮、吡唑并嘧啶酮和吡唑并吡啶酮
EP3532064B1 (fr) 2016-10-28 2020-07-29 H. Lundbeck A/S Traitements combinés comprenant des imidazopyrazinones pour le traitement de troubles psychiatriques et/ou cognitifs
KR20190077349A (ko) 2016-10-28 2019-07-03 하. 룬드벡 아크티에셀스카브 이미다조피라지논의 투여를 포함하는 병용 치료
KR102590848B1 (ko) 2016-12-28 2023-10-19 다트 뉴로사이언스, 엘엘씨 Pde2 억제제로서 치환된 피라졸로피리미디논 화합물
AR112457A1 (es) * 2017-08-02 2019-10-30 Lilly Co Eli Derivados de [1,2,4]triazolo[4,3-a]pirazin-6(5h)-ona
TW201920188A (zh) 2017-08-10 2019-06-01 美商美國禮來大藥廠 [1,2,4]三唑衍生物
JP7254078B2 (ja) * 2017-11-27 2023-04-07 ダート・ニューロサイエンス・エルエルシー Pde1阻害剤としての置換フラノピリミジン化合物
US11453673B2 (en) 2018-02-06 2022-09-27 Eli Lilly And Company Substituted [1,2,4]triazolo[4,3-a]pyrazines as phosphodiesterase inhibitors
WO2021035157A1 (fr) * 2019-08-22 2021-02-25 Intra-Cellular Therapies, Inc. Composés organiques
WO2022138757A1 (fr) * 2020-12-24 2022-06-30 デンカ株式会社 Construction d'adn, vecteur, bactérie et procédé de production de polypeptide
WO2025059641A1 (fr) 2023-09-14 2025-03-20 Eli Lilly And Company Inhibiteurs de la pde1

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
FR2662163A1 (fr) * 1990-05-16 1991-11-22 Lipha Nouvelles 8-amino-1,2,4-triazolo(4,3-a) pyrazines, procedes de preparation et medicaments les contenant.
AU9651198A (en) * 1997-11-11 1999-05-31 Ono Pharmaceutical Co. Ltd. Fused pyrazine compounds
DE19858331A1 (de) * 1998-12-17 2000-06-21 Boehringer Ingelheim Pharma Tricyclische Stickstoffheterocyclen als PDE IV Inhibitoren
CA2671980C (fr) 2006-12-13 2015-05-05 Aska Pharmaceutical Co., Ltd. Derive de quinoxaline
WO2008103357A1 (fr) 2007-02-21 2008-08-28 E. I. Du Pont De Nemours And Company 1,2,4-triazoles tricycliques fongicides
JP5822080B2 (ja) 2010-09-07 2015-11-24 アステラス製薬株式会社 キノキサリン化合物
AU2013277294C1 (en) 2012-06-18 2018-02-08 Dart Neuroscience (Cayman) Ltd Substituted thiophene- and furan-fused azolopyrimidine-5-(6h)-one compounds

Also Published As

Publication number Publication date
US20170233396A1 (en) 2017-08-17
TW201736372A (zh) 2017-10-16
US10112951B2 (en) 2018-10-30
ES2879645T3 (es) 2021-11-22
US9868741B2 (en) 2018-01-16
AR107456A1 (es) 2018-05-02
US20180099973A1 (en) 2018-04-12
JP6533875B2 (ja) 2019-06-19
JP2019503389A (ja) 2019-02-07
EP3414249B1 (fr) 2021-06-23
CN108602835A (zh) 2018-09-28
EP3414249A1 (fr) 2018-12-19
TWI609870B (zh) 2018-01-01
WO2017139186A1 (fr) 2017-08-17

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