MA44127A - Procédés de synthèse pour la préparation de di(4-méthylbenzènesulfonate) de 2-amino-3-méthylbutanoate de (s)-(2r,3r,11br)-3-isobutyl-9,10-diméthoxy-2,3,4,6,7,11b-hexahydro-1h-pyrido[2,1,-a]isoquinoléin-2-yl - Google Patents

Procédés de synthèse pour la préparation de di(4-méthylbenzènesulfonate) de 2-amino-3-méthylbutanoate de (s)-(2r,3r,11br)-3-isobutyl-9,10-diméthoxy-2,3,4,6,7,11b-hexahydro-1h-pyrido[2,1,-a]isoquinoléin-2-yl

Info

Publication number
MA44127A
MA44127A MA044127A MA44127A MA44127A MA 44127 A MA44127 A MA 44127A MA 044127 A MA044127 A MA 044127A MA 44127 A MA44127 A MA 44127A MA 44127 A MA44127 A MA 44127A
Authority
MA
Morocco
Prior art keywords
isoquinolein
methylbutanoate
pyrido
hexahydro
dimethoxy
Prior art date
Application number
MA044127A
Other languages
English (en)
Inventor
Bin-Feng Li
Kevin Mcgee
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57758848&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA44127(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of MA44127A publication Critical patent/MA44127A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA044127A 2015-12-23 2016-12-22 Procédés de synthèse pour la préparation de di(4-méthylbenzènesulfonate) de 2-amino-3-méthylbutanoate de (s)-(2r,3r,11br)-3-isobutyl-9,10-diméthoxy-2,3,4,6,7,11b-hexahydro-1h-pyrido[2,1,-a]isoquinoléin-2-yl MA44127A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562387442P 2015-12-23 2015-12-23

Publications (1)

Publication Number Publication Date
MA44127A true MA44127A (fr) 2018-10-31

Family

ID=57758848

Family Applications (1)

Application Number Title Priority Date Filing Date
MA044127A MA44127A (fr) 2015-12-23 2016-12-22 Procédés de synthèse pour la préparation de di(4-méthylbenzènesulfonate) de 2-amino-3-méthylbutanoate de (s)-(2r,3r,11br)-3-isobutyl-9,10-diméthoxy-2,3,4,6,7,11b-hexahydro-1h-pyrido[2,1,-a]isoquinoléin-2-yl

Country Status (16)

Country Link
US (6) US10160757B2 (fr)
EP (1) EP3394057B1 (fr)
JP (4) JP6869988B2 (fr)
CN (2) CN121045173A (fr)
CY (1) CY1125320T1 (fr)
DK (1) DK3394057T3 (fr)
ES (1) ES2911351T3 (fr)
HR (1) HRP20220621T1 (fr)
HU (1) HUE059065T2 (fr)
LT (1) LT3394057T (fr)
MA (1) MA44127A (fr)
PL (1) PL3394057T3 (fr)
PT (1) PT3394057T (fr)
RS (1) RS63170B1 (fr)
SI (1) SI3394057T1 (fr)
WO (1) WO2017112857A1 (fr)

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JP2019500372A (ja) 2019-01-10
CN108925135B (zh) 2025-09-19
US20200347056A1 (en) 2020-11-05
ES2911351T3 (es) 2022-05-18
US20200347054A1 (en) 2020-11-05
US20200347055A1 (en) 2020-11-05
US10919892B2 (en) 2021-02-16
JP2023068137A (ja) 2023-05-16
CY1125320T1 (el) 2025-03-28
LT3394057T (lt) 2022-06-27
EP3394057A1 (fr) 2018-10-31
RS63170B1 (sr) 2022-05-31
JP2021046454A (ja) 2021-03-25
HRP20220621T1 (hr) 2022-06-24
EP3394057B1 (fr) 2022-03-30
PL3394057T3 (pl) 2022-08-22
US20200181140A1 (en) 2020-06-11
US10906903B2 (en) 2021-02-02
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WO2017112857A1 (fr) 2017-06-29
SI3394057T1 (sl) 2022-06-30
JP2025096506A (ja) 2025-06-26
US10906902B2 (en) 2021-02-02
CN121045173A (zh) 2025-12-02
US10160757B2 (en) 2018-12-25
US20170183346A1 (en) 2017-06-29
DK3394057T3 (da) 2022-04-11
PT3394057T (pt) 2022-04-21
US20200347057A1 (en) 2020-11-05
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CA3009169A1 (fr) 2017-06-29
CN108925135A (zh) 2018-11-30

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