MA45221A - Nouveaux composés antibactériens - Google Patents

Nouveaux composés antibactériens

Info

Publication number: MA45221A
Authority: MA; Morocco
Prior art keywords: antibacterial compounds; new antibacterial; new; compounds; antibacterial
Prior art date: 2016-06-08

Application number

MA045221A

Other languages

English (en)

Inventor

De Joannon Alessandra Capezzone

Guido Furlotti

Barbara Garofalo

Gabriele Magaró

Giorgina Mangano

Rosella Ombrato

Original Assignee

Acraf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-06-08

Filing date

2017-06-05

Publication date

2021-05-19

2017-06-05 Application filed by Acraf filed Critical Acraf

2021-05-19 Publication of MA45221A publication Critical patent/MA45221A/fr

Links

230000000844 anti-bacterial effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

MA045221A 2016-06-08 2017-06-05 Nouveaux composés antibactériens MA45221A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP16173550		2016-06-08

Publications (1)

Publication Number	Publication Date
MA45221A true MA45221A (fr)	2021-05-19

Family

ID=56116327

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA045221A MA45221A (fr)	2016-06-08	2017-06-05	Nouveaux composés antibactériens

Country Status (28)

Country	Link
US (2)	US10640488B2 (fr)
EP (2)	EP3468975B1 (fr)
JP (2)	JP2019517545A (fr)
KR (2)	KR20190019084A (fr)
CN (2)	CN109415373A (fr)
AR (2)	AR108778A1 (fr)
AU (2)	AU2017276627A1 (fr)
BR (2)	BR112018075297A2 (fr)
CA (2)	CA3025270A1 (fr)
CY (1)	CY1123194T1 (fr)
DK (1)	DK3468975T3 (fr)
EA (2)	EA201892822A1 (fr)
ES (1)	ES2802233T3 (fr)
HR (1)	HRP20200894T1 (fr)
HU (1)	HUE049547T2 (fr)
IL (2)	IL263285A (fr)
LT (1)	LT3468975T (fr)
MA (1)	MA45221A (fr)
MD (1)	MD3468975T2 (fr)
ME (1)	ME03738B (fr)
MX (2)	MX2018015125A (fr)
PL (1)	PL3468975T3 (fr)
PT (1)	PT3468975T (fr)
RS (1)	RS60511B1 (fr)
SG (2)	SG11201810389XA (fr)
SI (1)	SI3468975T1 (fr)
SM (1)	SMT202000335T1 (fr)
WO (2)	WO2017211760A1 (fr)

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* Cited by examiner, † Cited by third party
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ME03738B (fr) *	2016-06-08	2021-01-20	Acraf	Nouveaux composés antibactériens
AU2021219053A1 (en)	2020-02-10	2022-07-28	Virox Technologies Inc.	Antimicrobial compositions containing peroxyphthalic acid and/or salt thereof
KR20230124583A (ko)	2020-11-23	2023-08-25	이난타 파마슈티칼스, 인코포레이티드	신규한 스피로피롤리딘 유래 항바이러스제
WO2022235605A1 (fr)	2021-05-04	2022-11-10	Enanta Pharmaceuticals, Inc.	Nouveaux agents antiviraux macrocycliques
CN113698412A (zh) *	2021-09-01	2021-11-26	临沂大学	一种香豆素并[4,3-b]吡咯类衍生物及其合成方法和应用
US11912714B2 (en)	2021-11-12	2024-02-27	Enanta Pharmaceuticals, Inc.	Spiropyrrolidine derived antiviral agents
US11919910B2 (en)	2021-11-12	2024-03-05	Enanta Pharmaceuticals, Inc.	Spiropyrrolidine derived antiviral agents
US11858945B2 (en)	2021-11-12	2024-01-02	Enanta Pharmaceuticals, Inc.	Alkyne-containing antiviral agents
WO2023107419A1 (fr)	2021-12-08	2023-06-15	Enanta Pharmaceuticals, Inc.	Composés spirocycliques saturés utilisés comme agents antiviraux
WO2023137007A1 (fr) *	2022-01-11	2023-07-20	Enanta Pharmaceuticals, Inc.	Procédés de préparation d'acide 4,6,7-trifluoro-1h-indole-2-carboxylique
WO2023196307A1 (fr)	2022-04-05	2023-10-12	Enanta Pharmaceuticals, Inc.	Nouveaux agents antiviraux dérivés de spiropyrrolidine
CN115850672B (zh) *	2022-11-25	2024-07-19	浙江甬仑聚嘉新材料有限公司	一种液晶聚合物及其制备方法和应用

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MX9201991A (es) *	1991-05-02	1992-11-01	Jonh Wyeth & Brother Limited	Derivados de piperazina y procedimiento para su preparacion.
US5607936A (en)	1994-09-30	1997-03-04	Merck & Co., Inc.	Substituted aryl piperazines as neurokinin antagonists
FR2822154B1 (fr)	2001-03-13	2005-10-21	Aventis Pharma Sa	Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
MXPA04012440A (es) *	2002-06-12	2005-04-28	Abbott Lab	Antagonistas de receptor de hormona concentradora de melanina.
DE102004041163A1 (de)	2004-08-25	2006-03-02	Morphochem Aktiengesellschaft für kombinatorische Chemie	Neue Verbindungen mit antibakterieller Aktivität
JP5314244B2 (ja) *	2004-10-27	2013-10-16	富山化学工業株式会社	新規な含窒素複素環化合物およびその塩
JP5023054B2 (ja)	2005-03-31	2012-09-12	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	抗バクテリア剤としての二環式ピラゾール化合物
MX2007014507A (es) *	2005-05-24	2008-02-07	Astrazeneca Ab	Aminopiperidin quinolinas y sus analogos azaisostericos con actividad antibacteriana.
MY150958A (en) *	2005-06-16	2014-03-31	Astrazeneca Ab	Compounds for the treatment of multi-drug resistant bacterial infections
EP1900732A4 (fr) *	2005-06-24	2009-11-18	Toyama Chemical Co Ltd	Nouveau composé hétérocyclique azoté et sel de celui-ci
CN101346379A (zh) *	2005-10-21	2009-01-14	葛兰素集团有限公司	用作抗菌剂的周环并合的三环化合物
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JP5620636B2 (ja) *	2007-11-26	2014-11-05	富山化学工業株式会社	新規な複素環化合物またはその塩を含有する抗菌剤
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CA2725726A1 (fr)	2008-05-23	2009-11-26	Glaxo Group Limited	Composes contenant de l'azote tricyclique et utilisation de ceux-ci comme antibacteriens
TW201022279A (en) *	2008-11-14	2010-06-16	Astrazeneca Ab	Chemical compounds
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CA2840060A1 (fr) *	2011-06-27	2013-01-03	Kyorin Pharmaceutical Co., Ltd.	Composes bicycliques pontes pour le traitement des infections bacteriennes
SG11201401710PA (en)	2011-11-08	2014-09-26	Actelion Pharmaceuticals Ltd	2-oxo-oxazolidin-3,5-diyl antibiotic derivatives
TW201326180A (zh)	2011-11-30	2013-07-01	Actelion Pharmaceuticals Ltd	３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素
CN105218501A (zh) *	2014-07-03	2016-01-06	南京大学	含哌嗪环的香豆素类衍生物及其制备与在抗菌药物中的应用
US10702521B2 (en)	2014-08-22	2020-07-07	Glaxosmithkline Intellectual Property Development Limited	Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones
MA41169A (fr) *	2014-12-17	2017-10-24	Acraf	Composés antibactériens à large spectre d'activité
MA41168A (fr) *	2014-12-17	2017-10-24	Acraf	Nouveaux composés antibactériens
ME03738B (fr) *	2016-06-08	2021-01-20	Acraf	Nouveaux composés antibactériens

2017
- 2017-06-05 ME MEP-2020-112A patent/ME03738B/fr unknown
- 2017-06-05 SM SM20200335T patent/SMT202000335T1/it unknown
- 2017-06-05 EP EP17732775.6A patent/EP3468975B1/fr active Active
- 2017-06-05 PL PL17732775T patent/PL3468975T3/pl unknown
- 2017-06-05 EA EA201892822A patent/EA201892822A1/ru unknown
- 2017-06-05 US US16/307,193 patent/US10640488B2/en not_active Expired - Fee Related
- 2017-06-05 JP JP2018564236A patent/JP2019517545A/ja active Pending
- 2017-06-05 AU AU2017276627A patent/AU2017276627A1/en not_active Abandoned
- 2017-06-05 CA CA3025270A patent/CA3025270A1/fr not_active Abandoned
- 2017-06-05 JP JP2018564240A patent/JP2019517546A/ja active Pending
- 2017-06-05 CN CN201780039687.1A patent/CN109415373A/zh active Pending
- 2017-06-05 HU HUE17732775A patent/HUE049547T2/hu unknown
- 2017-06-05 CA CA3025624A patent/CA3025624A1/fr not_active Abandoned
- 2017-06-05 KR KR1020187036946A patent/KR20190019084A/ko not_active Ceased
- 2017-06-05 EP EP17727595.5A patent/EP3468970A1/fr not_active Withdrawn
- 2017-06-05 DK DK17732775.6T patent/DK3468975T3/da active
- 2017-06-05 WO PCT/EP2017/063601 patent/WO2017211760A1/fr not_active Ceased
- 2017-06-05 SG SG11201810389XA patent/SG11201810389XA/en unknown
- 2017-06-05 WO PCT/EP2017/063600 patent/WO2017211759A1/fr not_active Ceased
- 2017-06-05 HR HRP20200894TT patent/HRP20200894T1/hr unknown
- 2017-06-05 SG SG11201810352XA patent/SG11201810352XA/en unknown
- 2017-06-05 LT LTEP17732775.6T patent/LT3468975T/lt unknown
- 2017-06-05 MA MA045221A patent/MA45221A/fr unknown
- 2017-06-05 KR KR1020187036945A patent/KR20190019083A/ko not_active Ceased
- 2017-06-05 MX MX2018015125A patent/MX2018015125A/es unknown
- 2017-06-05 PT PT177327756T patent/PT3468975T/pt unknown
- 2017-06-05 MX MX2018015126A patent/MX2018015126A/es unknown
- 2017-06-05 US US16/307,410 patent/US10633366B2/en not_active Expired - Fee Related
- 2017-06-05 AU AU2017276626A patent/AU2017276626A1/en not_active Abandoned
- 2017-06-05 BR BR112018075297-5A patent/BR112018075297A2/pt not_active IP Right Cessation
- 2017-06-05 BR BR112018075334-3A patent/BR112018075334A2/pt not_active IP Right Cessation
- 2017-06-05 SI SI201730306T patent/SI3468975T1/sl unknown
- 2017-06-05 EA EA201892815A patent/EA201892815A1/ru unknown
- 2017-06-05 ES ES17732775T patent/ES2802233T3/es active Active
- 2017-06-05 MD MDE20190471T patent/MD3468975T2/ro not_active IP Right Cessation
- 2017-06-05 CN CN201780042649.1A patent/CN109790157A/zh active Pending
- 2017-06-05 RS RS20200735A patent/RS60511B1/sr unknown
- 2017-06-07 AR ARP170101555A patent/AR108778A1/es unknown
- 2017-06-07 AR ARP170101554A patent/AR108777A1/es unknown
2018
- 2018-11-26 IL IL263285A patent/IL263285A/en unknown
- 2018-11-26 IL IL263283A patent/IL263283A/en unknown
2020
- 2020-06-29 CY CY20201100597T patent/CY1123194T1/el unknown

Also Published As

Publication number	Publication date
LT3468975T (lt)	2020-08-10
WO2017211759A1 (fr)	2017-12-14
BR112018075297A2 (pt)	2019-03-19
US10633366B2 (en)	2020-04-28
ME03738B (fr)	2021-01-20
CA3025624A1 (fr)	2017-12-14
PL3468975T3 (pl)	2020-09-07
SG11201810352XA (en)	2018-12-28
US20200095225A9 (en)	2020-03-26
SMT202000335T1 (it)	2020-07-08
US20190161472A1 (en)	2019-05-30
JP2019517546A (ja)	2019-06-24
US20190256495A1 (en)	2019-08-22
IL263285A (en)	2018-12-31
EA201892815A1 (ru)	2019-05-31
KR20190019084A (ko)	2019-02-26
CY1123194T1 (el)	2021-10-29
CN109415373A (zh)	2019-03-01
AR108778A1 (es)	2018-09-26
AU2017276627A1 (en)	2018-12-20
EP3468975B1 (fr)	2020-04-01
HUE049547T2 (hu)	2020-10-28
ES2802233T3 (es)	2021-01-18
DK3468975T3 (da)	2020-07-13
CA3025270A1 (fr)	2017-12-14
EP3468975A1 (fr)	2019-04-17
AU2017276626A1 (en)	2018-12-20
PT3468975T (pt)	2020-06-23
KR20190019083A (ko)	2019-02-26
MX2018015125A (es)	2019-09-02
CN109790157A (zh)	2019-05-21
US10640488B2 (en)	2020-05-05
EA201892822A1 (ru)	2019-06-28
WO2017211760A1 (fr)	2017-12-14
JP2019517545A (ja)	2019-06-24
BR112018075334A2 (pt)	2019-03-19
AR108777A1 (es)	2018-09-26
EP3468970A1 (fr)	2019-04-17
SI3468975T1 (sl)	2020-08-31
IL263283A (en)	2018-12-31
MX2018015126A (es)	2019-09-02
RS60511B1 (sr)	2020-08-31
HRP20200894T1 (hr)	2020-09-18
MD3468975T2 (ro)	2020-08-31
SG11201810389XA (en)	2018-12-28

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