MA45502A - Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines ayant une respiration mitochondriale glucose-dépendante et une réponse en sécrétion d'insuline en deux phases - Google Patents

Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines ayant une respiration mitochondriale glucose-dépendante et une réponse en sécrétion d'insuline en deux phases

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Publication number
MA45502A
MA45502A MA045502A MA45502A MA45502A MA 45502 A MA45502 A MA 45502A MA 045502 A MA045502 A MA 045502A MA 45502 A MA45502 A MA 45502A MA 45502 A MA45502 A MA 45502A
Authority
MA
Morocco
Prior art keywords
glucose
generation
pluripotent stem
insulin secretion
human pluripotent
Prior art date
Application number
MA045502A
Other languages
English (en)
Inventor
Alireza Rezania
Sebastian Rieck
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA45502A publication Critical patent/MA45502A/fr

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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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MA045502A 2016-06-21 2017-06-14 Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines ayant une respiration mitochondriale glucose-dépendante et une réponse en sécrétion d'insuline en deux phases MA45502A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662352968P 2016-06-21 2016-06-21

Publications (1)

Publication Number Publication Date
MA45502A true MA45502A (fr) 2019-04-24

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ID=60659269

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Application Number Title Priority Date Filing Date
MA045502A MA45502A (fr) 2016-06-21 2017-06-14 Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines ayant une respiration mitochondriale glucose-dépendante et une réponse en sécrétion d'insuline en deux phases
MA71715A MA71715B1 (fr) 2016-06-21 2017-06-14 Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines présentant une réponse de respiration mitochondriale dépendant du glucose et de sécrétion d'insuline en deux phases

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MA71715A MA71715B1 (fr) 2016-06-21 2017-06-14 Génération de cellules bêta fonctionnelles dérivées de cellules souches pluripotentes humaines présentant une réponse de respiration mitochondriale dépendant du glucose et de sécrétion d'insuline en deux phases

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US (3) US10633635B2 (fr)
EP (3) EP4691479A2 (fr)
JP (4) JP7044726B2 (fr)
KR (5) KR102607813B1 (fr)
CN (2) CN109415693B (fr)
AR (1) AR108847A1 (fr)
AU (3) AU2017282638C1 (fr)
CA (1) CA3027879A1 (fr)
DK (2) DK3472303T3 (fr)
ES (2) ES3058926T3 (fr)
FI (1) FI4194548T3 (fr)
HR (1) HRP20260022T1 (fr)
LT (1) LT4194548T (fr)
MA (2) MA45502A (fr)
MD (1) MD4194548T2 (fr)
PL (1) PL4194548T3 (fr)
PT (1) PT4194548T (fr)
RS (1) RS67611B1 (fr)
RU (1) RU2752499C2 (fr)
SG (1) SG11201810550WA (fr)
SM (1) SMT202600006T1 (fr)
TW (1) TW201809266A (fr)
WO (1) WO2017222879A1 (fr)

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US20200199540A1 (en) * 2017-09-11 2020-06-25 Novo Nordisk A/S Enrichment of nkx6.1 and c-peptide co-expressing cells derived in vitro from stem cells
AU2018370029B2 (en) 2017-11-15 2024-11-07 Vertex Pharmaceuticals Incorporated Islet cell manufacturing compositions and methods of use
IL277025B2 (en) * 2018-03-02 2024-04-01 Vertex Pharma Methods of enhancing stem cell differentiation into beta cells
WO2019208788A1 (fr) * 2018-04-27 2019-10-31 株式会社カネカ Procédé de production de cellules bêta pancréatiques
CN112867497A (zh) * 2018-05-07 2021-05-28 哈佛学院校长同事会 与体外β细胞分化相关的细胞群和基因表达
WO2019217875A1 (fr) * 2018-05-11 2019-11-14 Cornell University Procédé d'induction d'une différentiation de cellules souches pluripotentes humaines en cellules monohormonales
WO2020033879A1 (fr) 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Différenciation d'ilot dérivé de cellules souches
US12378572B2 (en) 2018-09-07 2025-08-05 Crispr Therapeutics Ag Universal donor cells
AU2020283056B2 (en) 2019-05-31 2023-06-08 Viacyte, Inc. A biocompatible membrane composite
WO2020243666A1 (fr) 2019-05-31 2020-12-03 W. L. Gore & Associates, Inc. Composite à membrane biocompatible
CA3139292C (fr) 2019-05-31 2025-06-10 Viacyte, Inc. Dispositifs d'encapsulation de cellules présentant des distances de diffusion d’oxygène régulées
AU2020282355B2 (en) 2019-05-31 2023-11-02 Viacyte, Inc. A biocompatible membrane composite
EP3990624A1 (fr) * 2019-06-25 2022-05-04 Vertex Pharmaceuticals Incorporated Différenciation améliorée de cellules bêta
AU2020303575B2 (en) * 2019-06-27 2026-02-05 Dana-Farber Cancer Institute, Inc. Compounds, compositions, and methods for protein degradation
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