MA45685A - Formes cristallines de 4-cyano-n-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamide - Google Patents
Formes cristallines de 4-cyano-n-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamideInfo
- Publication number
- MA45685A MA45685A MA045685A MA45685A MA45685A MA 45685 A MA45685 A MA 45685A MA 045685 A MA045685 A MA 045685A MA 45685 A MA45685 A MA 45685A MA 45685 A MA45685 A MA 45685A
- Authority
- MA
- Morocco
- Prior art keywords
- tetramethyltetrahydro
- dimethylcyclohex
- pyran
- carboxamide
- pyridin
- Prior art date
Links
- BNVPFDRNGHMRJS-UHFFFAOYSA-N 5-cyano-n-[2-(4,4-dimethylcyclohexen-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)pyridin-3-yl]-1h-imidazole-2-carboxamide Chemical compound C1C(C)(C)CCC(C=2C(=CC=C(N=2)C2CC(C)(C)OC(C)(C)C2)NC(=O)C=2NC=C(N=2)C#N)=C1 BNVPFDRNGHMRJS-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- AIDS & HIV (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662363622P | 2016-07-18 | 2016-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA45685A true MA45685A (fr) | 2019-05-22 |
Family
ID=59631847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA045685A MA45685A (fr) | 2016-07-18 | 2017-07-17 | Formes cristallines de 4-cyano-n-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamide |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10314821B2 (fr) |
| EP (1) | EP3484872B1 (fr) |
| JP (1) | JP2019521159A (fr) |
| KR (1) | KR20190026910A (fr) |
| CN (1) | CN109952296A (fr) |
| AR (1) | AR109079A1 (fr) |
| AU (1) | AU2017299506B2 (fr) |
| BR (1) | BR112019000982A2 (fr) |
| CA (1) | CA3031230A1 (fr) |
| EA (1) | EA201990320A1 (fr) |
| ES (1) | ES2935647T3 (fr) |
| MA (1) | MA45685A (fr) |
| MX (2) | MX384614B (fr) |
| TW (1) | TWI752980B (fr) |
| UY (1) | UY37338A (fr) |
| WO (1) | WO2018017444A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022094077A1 (fr) * | 2020-10-30 | 2022-05-05 | Athenex R&D, Llc | Polymorphismes de mésylate hm30181 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3240B1 (ar) * | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | c-fms مثبطات كيناز |
| WO2009058968A2 (fr) * | 2007-10-31 | 2009-05-07 | Janssen Pharmaceutica N.V. | Biomarqueur utilisé pour évaluer une réponse à un traitement de fms |
| ES2658773T3 (es) | 2012-08-07 | 2018-03-12 | Janssen Pharmaceutica N.V. | Procedimiento de sulfonilación usando fluoruro de nonafluorobutanosulfonilo |
| MX2015012344A (es) * | 2013-03-15 | 2016-06-02 | Janssen Pharmaceutica Nv | 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il)-6-(2,2,6,6-tetrameti ltetrahidro-2h-piran-4-il)piridin-3-il)-1h-imidazol-2-carboxamida para el tratamiento de linfona de hodgkin. |
| WO2014151258A1 (fr) * | 2013-03-15 | 2014-09-25 | Janssen Pharmaceutica Nv | Dérivés de pyridine substitués utiles en tant qu'inhibiteurs de kinase c-fms |
-
2017
- 2017-07-14 TW TW106123583A patent/TWI752980B/zh not_active IP Right Cessation
- 2017-07-17 MA MA045685A patent/MA45685A/fr unknown
- 2017-07-17 AR ARP170101991A patent/AR109079A1/es not_active Application Discontinuation
- 2017-07-17 EP EP17752511.0A patent/EP3484872B1/fr active Active
- 2017-07-17 CN CN201780057364.5A patent/CN109952296A/zh active Pending
- 2017-07-17 CA CA3031230A patent/CA3031230A1/fr active Pending
- 2017-07-17 BR BR112019000982-5A patent/BR112019000982A2/pt not_active Application Discontinuation
- 2017-07-17 ES ES17752511T patent/ES2935647T3/es active Active
- 2017-07-17 US US15/651,385 patent/US10314821B2/en active Active
- 2017-07-17 WO PCT/US2017/042310 patent/WO2018017444A1/fr not_active Ceased
- 2017-07-17 MX MX2019000749A patent/MX384614B/es unknown
- 2017-07-17 KR KR1020197004327A patent/KR20190026910A/ko not_active Ceased
- 2017-07-17 EA EA201990320A patent/EA201990320A1/ru unknown
- 2017-07-17 AU AU2017299506A patent/AU2017299506B2/en not_active Ceased
- 2017-07-17 JP JP2019502219A patent/JP2019521159A/ja active Pending
- 2017-07-19 UY UY0001037338A patent/UY37338A/es unknown
-
2019
- 2019-01-17 MX MX2021006739A patent/MX2021006739A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190026910A (ko) | 2019-03-13 |
| TWI752980B (zh) | 2022-01-21 |
| UY37338A (es) | 2018-01-31 |
| WO2018017444A1 (fr) | 2018-01-25 |
| US10314821B2 (en) | 2019-06-11 |
| US20180133197A1 (en) | 2018-05-17 |
| JP2019521159A (ja) | 2019-07-25 |
| CA3031230A1 (fr) | 2018-01-25 |
| MX2019000749A (es) | 2019-08-29 |
| ES2935647T3 (es) | 2023-03-08 |
| EP3484872A1 (fr) | 2019-05-22 |
| EA201990320A1 (ru) | 2019-06-28 |
| MX2021006739A (es) | 2021-07-15 |
| MX384614B (es) | 2025-03-14 |
| CN109952296A (zh) | 2019-06-28 |
| AU2017299506B2 (en) | 2021-08-05 |
| EP3484872B1 (fr) | 2022-11-30 |
| TW201808941A (zh) | 2018-03-16 |
| AR109079A1 (es) | 2018-10-24 |
| AU2017299506A1 (en) | 2019-02-07 |
| BR112019000982A2 (pt) | 2019-05-14 |
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