MA46242A - Composés inhibiteurs de bêta-lactamase - Google Patents
Composés inhibiteurs de bêta-lactamaseInfo
- Publication number
- MA46242A MA46242A MA046242A MA46242A MA46242A MA 46242 A MA46242 A MA 46242A MA 046242 A MA046242 A MA 046242A MA 46242 A MA46242 A MA 46242A MA 46242 A MA46242 A MA 46242A
- Authority
- MA
- Morocco
- Prior art keywords
- beta
- inhibitor compounds
- lactamase inhibitor
- lactamase
- compounds
- Prior art date
Links
- 239000003781 beta lactamase inhibitor Substances 0.000 title 1
- 229940126813 beta-lactamase inhibitor Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940126085 β‑Lactamase Inhibitor Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
- C07F7/0892—Compounds with a Si-O-N linkage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395464P | 2016-09-16 | 2016-09-16 | |
| US201762456423P | 2017-02-08 | 2017-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46242A true MA46242A (fr) | 2019-07-24 |
Family
ID=60083416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046242A MA46242A (fr) | 2016-09-16 | 2017-09-15 | Composés inhibiteurs de bêta-lactamase |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10800778B2 (fr) |
| EP (1) | EP3512851B1 (fr) |
| JP (2) | JP6997178B2 (fr) |
| KR (2) | KR102537340B1 (fr) |
| CN (2) | CN114591223B (fr) |
| AU (1) | AU2017325863B2 (fr) |
| CA (1) | CA3036557A1 (fr) |
| DK (1) | DK3512851T3 (fr) |
| ES (1) | ES2927986T3 (fr) |
| HR (1) | HRP20221217T1 (fr) |
| HU (1) | HUE060282T2 (fr) |
| IL (2) | IL289686B2 (fr) |
| LT (1) | LT3512851T (fr) |
| MA (1) | MA46242A (fr) |
| MX (2) | MX385507B (fr) |
| PH (1) | PH12019500558B1 (fr) |
| PL (1) | PL3512851T3 (fr) |
| PT (1) | PT3512851T (fr) |
| SG (1) | SG11201901658PA (fr) |
| SI (1) | SI3512851T1 (fr) |
| SM (1) | SMT202200397T1 (fr) |
| TW (1) | TWI773687B (fr) |
| WO (1) | WO2018053215A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA124464C2 (uk) | 2016-06-30 | 2021-09-22 | Кьюпекс Біофарма, Інк. | Похідні боронової кислоти та їх терапевтичні застосування |
| KR102537340B1 (ko) * | 2016-09-16 | 2023-05-26 | 엔타시스 테라퓨틱스 리미티드 | 베타-락타마제 억제제 화합물 |
| MA48743A (fr) | 2017-05-08 | 2020-04-08 | Entasis Therapeutics Inc | Composés et méthodes de traitement d'infections bactériennes |
| WO2019204419A1 (fr) | 2018-04-20 | 2019-10-24 | The Medicines Company (San Diego), Llc | Dérivés d'acide boronique et leurs utilisations thérapeutiques |
| CA3110111A1 (fr) | 2018-08-09 | 2020-02-13 | Antabio Sas | Diazabicyclooctanones en tant qu'inhibiteurs de beta-lactamases a serine |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| CN112209928B (zh) * | 2019-07-10 | 2023-02-17 | 华东理工大学 | 共价键标记丝氨酸类beta-内酰胺酶的试剂及制备和应用 |
| CN110898999A (zh) * | 2019-11-26 | 2020-03-24 | 中国矿业大学 | 一种煤焦油基煤泥浮选药剂及其制备方法 |
| AU2021266715A1 (en) | 2020-05-05 | 2022-11-17 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
| CN111790439B (zh) * | 2020-07-29 | 2022-12-27 | 成都能特科技发展有限公司 | 一种手性二级胺二苯基膦芳甲酰胺双功能催化剂及其制备方法与应用 |
| EP4146650B1 (fr) | 2020-09-01 | 2026-01-21 | Ningxia Academy of Agriculture and Forestry Sciences | Inhibiteurs de bêta-lactamase et leur préparation |
| CN117157078A (zh) * | 2021-04-05 | 2023-12-01 | Qpex生物制药有限公司 | 头孢布烯给药方案 |
| EP4146651B1 (fr) | 2021-05-07 | 2026-03-04 | Ningxia Academy of Agriculture and Forestry Sciences | Composés substitués de sulfonylamidine et leur utilisation en tant qu'inhibiteurs de bêta-lactamase |
| US11814385B2 (en) * | 2021-06-25 | 2023-11-14 | University Of South Florida | Small molecule inhibitors targeting Clostridioides difficile sporulation |
| WO2023206580A1 (fr) | 2022-04-29 | 2023-11-02 | Entasis Therapeutics Limited | Formes cristallines de durlobactam |
| US20230398101A1 (en) * | 2022-06-09 | 2023-12-14 | Fleurir Abx Llc | Co-agents as Therapy Against Anaerobic Pathogens |
| CN118271319B (zh) * | 2022-12-30 | 2025-02-28 | 成都四面体药物研究有限公司 | 一种β-内酰胺酶抑制剂含脲双环化合物、其制备方法及其用途 |
| CN118772145B (zh) * | 2023-04-04 | 2025-10-10 | 上海医药工业研究院有限公司 | 一种二氮杂双环辛烯化合物的制备方法 |
| CN116693531A (zh) * | 2023-06-09 | 2023-09-05 | 河南师范大学 | 一种桥联多环内酰胺类化合物的合成方法 |
| WO2025106662A1 (fr) * | 2023-11-15 | 2025-05-22 | Entasis Therapeutics, Inc. | Préparation d'intermédiaires d'acide boronique utiles dans la préparation de composés pour le traitement d'infections bactériennes |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4607041A (en) * | 1983-04-27 | 1986-08-19 | Fisons Plc | Antihypertensive 2-phenyl Hantzsch dihydropyridines |
| ATE177099T1 (de) | 1993-12-29 | 1999-03-15 | Pfizer | Diazabicyclische neurokinin antagonisten |
| FR2812635B1 (fr) | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2825705B1 (fr) | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2848210B1 (fr) | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
| US7439253B2 (en) | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| FR2914923B1 (fr) | 2007-04-12 | 2013-06-14 | Novexel | Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens. |
| CN101918407B (zh) * | 2008-01-18 | 2014-02-26 | 默沙东公司 | β-内酰胺酶抑制剂 |
| FR2930553B1 (fr) * | 2008-04-29 | 2010-05-21 | Novexel | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases |
| EP2921559A1 (fr) | 2008-06-19 | 2015-09-23 | Astra Zeneca Holding France | Utilisation de (1r, 2s, 5r) 1,6-diazabicyclo [3.2.1] octane-2-carboxamide, 7-oxo-6-(sulfooxy) -, sel monosodique en tant que réactif de diagnostic pour la détection de sérines bêta-lactamases |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2936951B1 (fr) | 2008-10-10 | 2010-12-03 | Novexel | Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments |
| FR2937034B1 (fr) | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
| FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| SMT201900482T1 (it) * | 2010-04-20 | 2019-09-09 | Fujifilm Toyama Chemical Co Ltd | Derivato dell'acido idrossammico |
| RU2569059C2 (ru) | 2011-07-26 | 2015-11-20 | Вокхардт Лимитед | Фармацевтические композиции, содержащие бета-лактамный антибиотик, сульбактам и ингибитор бета-лактамаз |
| JP5808860B2 (ja) | 2011-07-26 | 2015-11-10 | ウォックハート リミテッド | スルバクタム及びベータ−ラクタマーゼインヒビターを含む医薬組成物 |
| JP5666743B2 (ja) * | 2011-08-27 | 2015-02-12 | ウォックハート リミテッド | 1,6−ジアザビシクロ[3,2,1]オクタン−7−オン誘導体および細菌感染の処置におけるそれらの使用 |
| RU2570423C2 (ru) | 2011-08-30 | 2015-12-10 | Вокхардт Лимитед | Производные 1,6-диазабицикло[3.2.1]октан-7-она и их применение при лечении бактериальных инфекций |
| ES2640520T3 (es) | 2011-09-13 | 2017-11-03 | Wockhardt Limited | Compuestos que contienen nitrógeno y su uso |
| US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| US20150119363A1 (en) | 2012-02-15 | 2015-04-30 | Rempex Pharmaceuticals, Inc.. | Methods of treating bacterial infections |
| US8969570B2 (en) | 2012-03-30 | 2015-03-03 | Cubist Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| TW201343646A (zh) | 2012-03-30 | 2013-11-01 | Cubist Pharm Inc | 異□唑β-內醯胺酶抑制劑 |
| SG11201406123TA (en) | 2012-03-30 | 2014-10-30 | Cubist Pharm Inc | 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE β-LACTAMASE INHIBITORS |
| US8916709B2 (en) | 2012-03-30 | 2014-12-23 | Cubist Pharmaceuticals, Inc. | 1,2,4-oxadiazole and 1,2,4-thiadiazole β-lactamase inhibitors |
| AR090539A1 (es) * | 2012-04-02 | 2014-11-19 | Astrazeneca Ab | COMPUESTOS INHIBIDORES DE b LACTAMASA |
| WO2013180197A1 (fr) | 2012-05-30 | 2013-12-05 | Meiji Seikaファルマ株式会社 | NOUVEL INHIBITEUR DE β-LACTAMASE ET PROCÉDÉ DE PRODUCTION DE CELUI-CI |
| WO2014033560A1 (fr) | 2012-08-25 | 2014-03-06 | Wockhardt Limited | Dérivés de 1,6-diazabicyclo[3,2,1]octan-7-one et leur utilisation dans le traitement d'infections bactériennes |
| NZ706734A (en) | 2012-09-03 | 2016-05-27 | Wockhardt Ltd | Pharmaceutical compositions useful for the treatment or control of bacterial infections |
| CN110302203A (zh) | 2013-02-06 | 2019-10-08 | 辉瑞抗感染公司 | 用于治疗医院性肺炎的组合疗法 |
| WO2014141132A1 (fr) * | 2013-03-14 | 2014-09-18 | Naeja Pharmaceutical Inc. | Nouveaux composés hétérocycliques et leur utilisation en tant qu'agents antibactériens et inhibiteurs de β-lactamase |
| DK3221313T3 (en) | 2014-11-17 | 2019-04-08 | Entasis Therapeutics Ltd | COMBINATION THERAPY FOR TREATING INFECTIONS WITH RESISTANT BACTERIA |
| US10072006B2 (en) | 2015-03-31 | 2018-09-11 | Mutabilis | Heterocyclic compounds and their use in preventing or treating bacterial infections |
| KR102537340B1 (ko) * | 2016-09-16 | 2023-05-26 | 엔타시스 테라퓨틱스 리미티드 | 베타-락타마제 억제제 화합물 |
| KR20230007830A (ko) * | 2021-07-06 | 2023-01-13 | 현대자동차주식회사 | 고강성 저선팽창 열가소성 수지 조성물 및 이를 포함하는 성형체 |
-
2017
- 2017-09-15 KR KR1020197010376A patent/KR102537340B1/ko active Active
- 2017-09-15 PH PH1/2019/500558A patent/PH12019500558B1/en unknown
- 2017-09-15 MX MX2019003060A patent/MX385507B/es unknown
- 2017-09-15 MA MA046242A patent/MA46242A/fr unknown
- 2017-09-15 SG SG11201901658PA patent/SG11201901658PA/en unknown
- 2017-09-15 CN CN202210161577.5A patent/CN114591223B/zh active Active
- 2017-09-15 PT PT177840634T patent/PT3512851T/pt unknown
- 2017-09-15 KR KR1020237017457A patent/KR102667828B1/ko active Active
- 2017-09-15 PL PL17784063.4T patent/PL3512851T3/pl unknown
- 2017-09-15 CN CN201780057302.4A patent/CN109715630B/zh active Active
- 2017-09-15 US US16/333,900 patent/US10800778B2/en active Active
- 2017-09-15 HU HUE17784063A patent/HUE060282T2/hu unknown
- 2017-09-15 MX MX2021010077A patent/MX392515B/es unknown
- 2017-09-15 EP EP17784063.4A patent/EP3512851B1/fr active Active
- 2017-09-15 LT LTEPPCT/US2017/051692T patent/LT3512851T/lt unknown
- 2017-09-15 SI SI201731232T patent/SI3512851T1/sl unknown
- 2017-09-15 HR HRP20221217TT patent/HRP20221217T1/hr unknown
- 2017-09-15 TW TW106131860A patent/TWI773687B/zh active
- 2017-09-15 CA CA3036557A patent/CA3036557A1/fr active Pending
- 2017-09-15 SM SM20220397T patent/SMT202200397T1/it unknown
- 2017-09-15 IL IL289686A patent/IL289686B2/en unknown
- 2017-09-15 JP JP2019515241A patent/JP6997178B2/ja active Active
- 2017-09-15 ES ES17784063T patent/ES2927986T3/es active Active
- 2017-09-15 AU AU2017325863A patent/AU2017325863B2/en active Active
- 2017-09-15 WO PCT/US2017/051692 patent/WO2018053215A1/fr not_active Ceased
- 2017-09-15 DK DK17784063.4T patent/DK3512851T3/da active
-
2019
- 2019-03-11 IL IL265276A patent/IL265276B/en unknown
-
2021
- 2021-12-16 JP JP2021203942A patent/JP7281527B2/ja active Active
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| EP3728289A4 (fr) | Composés optimisés | |
| EP3717483A4 (fr) | Composés de pyrazolopyridinone | |
| EP3713941A4 (fr) | Composés de pyrazolopyridinone | |
| EP3504269A4 (fr) | Composés de fluoroélastomère | |
| LT3668879T (lt) | Nauji junginiai | |
| DK3672941T3 (da) | Pyridylpyridonforbindelser | |
| ME03735B (fr) | Inhibiteurs de bêta-lactamases | |
| MA43791A (fr) | Composés de carbapénème | |
| DK3672962T3 (da) | Morpholinylpyridonforbindelser | |
| MA48946A (fr) | Composés | |
| EP3795149A4 (fr) | Inhibiteur de beta-lactamase |