MA46585A - Méthodes de traitement de l'atrophie musculaire et des maladies osseuses faisant appel à de nouvelles protéines hybrides piégeant le ligand d'actriib - Google Patents
Méthodes de traitement de l'atrophie musculaire et des maladies osseuses faisant appel à de nouvelles protéines hybrides piégeant le ligand d'actriibInfo
- Publication number
- MA46585A MA46585A MA046585A MA46585A MA46585A MA 46585 A MA46585 A MA 46585A MA 046585 A MA046585 A MA 046585A MA 46585 A MA46585 A MA 46585A MA 46585 A MA46585 A MA 46585A
- Authority
- MA
- Morocco
- Prior art keywords
- trapping
- treatment
- methods
- muscle atrophy
- bone diseases
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662410595P | 2016-10-20 | 2016-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46585A true MA46585A (fr) | 2019-08-28 |
Family
ID=62019496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046585A MA46585A (fr) | 2016-10-20 | 2017-10-19 | Méthodes de traitement de l'atrophie musculaire et des maladies osseuses faisant appel à de nouvelles protéines hybrides piégeant le ligand d'actriib |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20190330307A1 (fr) |
| EP (2) | EP4714967A2 (fr) |
| JP (1) | JP2019535675A (fr) |
| KR (1) | KR20190071758A (fr) |
| CN (1) | CN109922821A (fr) |
| AU (1) | AU2017345435B2 (fr) |
| CA (1) | CA3039066A1 (fr) |
| CL (1) | CL2019001069A1 (fr) |
| CO (1) | CO2019005115A2 (fr) |
| CR (1) | CR20190247A (fr) |
| EA (1) | EA201990971A1 (fr) |
| ES (1) | ES3064852T3 (fr) |
| IL (1) | IL266032B2 (fr) |
| JO (1) | JOP20190085A1 (fr) |
| MA (1) | MA46585A (fr) |
| MX (1) | MX2019004651A (fr) |
| PE (1) | PE20190743A1 (fr) |
| PH (1) | PH12019500853A1 (fr) |
| SG (2) | SG11201903450YA (fr) |
| TN (1) | TN2019000119A1 (fr) |
| TW (1) | TWI826358B (fr) |
| WO (1) | WO2018075747A1 (fr) |
| ZA (1) | ZA201903105B (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017021510A2 (pt) | 2015-04-06 | 2018-07-03 | Acceleron Pharma Inc | heteromultímeros do receptor tipo i e tipo ii da superfamília tgf-beta e sua utilização |
| KR20170141215A (ko) | 2015-04-06 | 2017-12-22 | 악셀레론 파마 인코포레이티드 | 싱글-암 유형 i과 유형 ii 수용체 융합 단백질들 및 이들의 용도 |
| MA41919A (fr) | 2015-04-06 | 2018-02-13 | Acceleron Pharma Inc | Hétéromultimères alk4:actriib et leurs utilisations |
| KR102761094B1 (ko) | 2016-10-05 | 2025-02-03 | 악셀레론 파마 인코포레이티드 | 변이체 actriib 단백질 및 이의 용도 |
| WO2018067879A1 (fr) | 2016-10-05 | 2018-04-12 | Acceleron Pharma Inc. | Hétéromultimères alk4:actriib et leurs utilisations |
| JOP20190085A1 (ar) | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| CN119241685A (zh) | 2016-11-10 | 2025-01-03 | 科乐斯疗法公司 | 激活素受体iia型变体及其使用方法 |
| CN111801112A (zh) | 2017-11-09 | 2020-10-20 | 科乐斯疗法公司 | 激活素受体iia型变体及其使用方法 |
| KR20200109330A (ko) | 2018-01-12 | 2020-09-22 | 케로스 테라퓨틱스, 인크. | 액티빈 수용체 유형 iib 변이체 및 그의 사용 방법 |
| WO2019217715A1 (fr) | 2018-05-09 | 2019-11-14 | Keros Therapeutics, Inc. | Variants du récepteur de l'activine de type iia et leurs procédés d'utilisation |
| MX2022009553A (es) * | 2020-02-03 | 2022-11-07 | Acceleron Pharma Inc | Proteínas actriib variantes y sus usos. |
| EP4121088A4 (fr) * | 2020-03-20 | 2024-07-03 | Keros Therapeutics, Inc. | Procédés d'utilisation de variants de récepteur de l'activine de type iib |
| WO2021189006A1 (fr) * | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Procédés d'utilisation de variants du récepteur de l'activine de type iia |
| CA3176735A1 (fr) | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Chimeres de type ii du recepteur d'activine et leurs methodes d'utilisation |
| CN115427056A (zh) * | 2020-04-13 | 2022-12-02 | 细胞基因公司 | 使用actriib配体陷阱和菲卓替尼治疗贫血的方法 |
| EP4142769A4 (fr) | 2020-04-28 | 2024-05-15 | Acceleron Pharma Inc. | Protéines actrii et leur utilisation dans le traitement de l'hypertension pulmonaire post-capillaire |
| WO2022150590A1 (fr) * | 2021-01-08 | 2022-07-14 | Acceleron Pharma Inc. | Compositions et méthodes de traitement de l'hypertension pulmonaire |
| US20260092096A1 (en) * | 2024-05-14 | 2026-04-02 | 35Pharma Inc. | Activin receptor type iib variants and uses thereof |
| WO2026096847A1 (fr) * | 2024-11-01 | 2026-05-07 | Bristol-Myers Squibb Company | Méthodes de régulation de l'inflammation et de l'autophagie à l'aide de pièges à ligands actriib |
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| BR112017021510A2 (pt) | 2015-04-06 | 2018-07-03 | Acceleron Pharma Inc | heteromultímeros do receptor tipo i e tipo ii da superfamília tgf-beta e sua utilização |
| MA41919A (fr) * | 2015-04-06 | 2018-02-13 | Acceleron Pharma Inc | Hétéromultimères alk4:actriib et leurs utilisations |
| SI3286206T1 (sl) * | 2015-04-22 | 2021-07-30 | Biogen Ma Inc. | Novi hibridni proteini ligandske pasti actriib za zdravljenje bolezni zaradi izgube mišične mase |
| CA2996996A1 (fr) | 2015-08-31 | 2017-03-09 | National Research Council Of Canada | Molecules de fusion d'ectodomaines du recepteur du tgf-b et leurs utilisations |
| EP3370754B1 (fr) | 2015-11-04 | 2026-04-29 | Acceleron Pharma, Inc. | Méthodes pour augmenter les taux d'érythrocytes et traiter l'érythropoïèse inefficace |
| CA3005975A1 (fr) | 2015-11-23 | 2017-06-01 | Acceleron Pharma Inc. | Methode de traitement de troubles oculaires |
| WO2017192847A1 (fr) * | 2016-05-04 | 2017-11-09 | University Of Cincinnati | Thérapies de la fertilité femelle |
| KR20210082548A (ko) | 2016-06-13 | 2021-07-05 | 스칼러 락, 인크. | 미오스타틴 억제제의 용도 및 조합 요법 |
| KR102761094B1 (ko) * | 2016-10-05 | 2025-02-03 | 악셀레론 파마 인코포레이티드 | 변이체 actriib 단백질 및 이의 용도 |
| JOP20190085A1 (ar) | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| KR20200109330A (ko) * | 2018-01-12 | 2020-09-22 | 케로스 테라퓨틱스, 인크. | 액티빈 수용체 유형 iib 변이체 및 그의 사용 방법 |
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2017
- 2017-06-16 JO JOP/2019/0085A patent/JOP20190085A1/ar unknown
- 2017-10-18 TW TW106135727A patent/TWI826358B/zh active
- 2017-10-19 CR CR20190247A patent/CR20190247A/es unknown
- 2017-10-19 PE PE2019000842A patent/PE20190743A1/es unknown
- 2017-10-19 EA EA201990971A patent/EA201990971A1/ru unknown
- 2017-10-19 SG SG11201903450YA patent/SG11201903450YA/en unknown
- 2017-10-19 US US16/343,366 patent/US20190330307A1/en not_active Abandoned
- 2017-10-19 KR KR1020197014056A patent/KR20190071758A/ko not_active Ceased
- 2017-10-19 EP EP25226228.2A patent/EP4714967A2/fr active Pending
- 2017-10-19 WO PCT/US2017/057351 patent/WO2018075747A1/fr not_active Ceased
- 2017-10-19 TN TNP/2019/000119A patent/TN2019000119A1/en unknown
- 2017-10-19 AU AU2017345435A patent/AU2017345435B2/en active Active
- 2017-10-19 JP JP2019521409A patent/JP2019535675A/ja active Pending
- 2017-10-19 CA CA3039066A patent/CA3039066A1/fr active Pending
- 2017-10-19 MX MX2019004651A patent/MX2019004651A/es unknown
- 2017-10-19 EP EP17861941.7A patent/EP3528833B1/fr active Active
- 2017-10-19 CN CN201780069411.8A patent/CN109922821A/zh active Pending
- 2017-10-19 ES ES17861941T patent/ES3064852T3/es active Active
- 2017-10-19 MA MA046585A patent/MA46585A/fr unknown
- 2017-10-19 SG SG10201913301TA patent/SG10201913301TA/en unknown
- 2017-10-19 IL IL266032A patent/IL266032B2/en unknown
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2019
- 2019-04-17 PH PH12019500853A patent/PH12019500853A1/en unknown
- 2019-04-18 CL CL2019001069A patent/CL2019001069A1/es unknown
- 2019-05-17 ZA ZA2019/03105A patent/ZA201903105B/en unknown
- 2019-05-20 CO CONC2019/0005115A patent/CO2019005115A2/es unknown
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2021
- 2021-12-07 US US17/544,579 patent/US12187783B2/en active Active
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2024
- 2024-11-25 US US18/959,069 patent/US20250109183A1/en active Pending
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