MA48971A - Tétrahydrate de ligand h3, son procédé de préparation et compositions pharmaceutiques le comprenant - Google Patents
Tétrahydrate de ligand h3, son procédé de préparation et compositions pharmaceutiques le comprenantInfo
- Publication number
- MA48971A MA48971A MA048971A MA48971A MA48971A MA 48971 A MA48971 A MA 48971A MA 048971 A MA048971 A MA 048971A MA 48971 A MA48971 A MA 48971A MA 48971 A MA48971 A MA 48971A
- Authority
- MA
- Morocco
- Prior art keywords
- tetrahydrate
- ligand
- pharmaceutical compositions
- preparation process
- compositions including
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000004685 tetrahydrates Chemical class 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- ACQXFQGMLFJXEI-KRWDZBQOSA-N 4-[4-[3-[(3s)-3-methylpiperidin-1-yl]propoxy]phenyl]-1-oxidopyridin-1-ium Chemical compound C1[C@@H](C)CCCN1CCCOC1=CC=C(C=2C=C[N+]([O-])=CC=2)C=C1 ACQXFQGMLFJXEI-KRWDZBQOSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Abstract
La présente invention concerne la forme tétrahydrate du composé : (3s)-4-{4-[3-(3-méthylpipéridin-1-yl)propoxy]phényl}pyridine 1-oxide, dichlorhydrate, son procédé de préparation et ses utilisations thérapeutiques.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305310.9A EP3378858A1 (fr) | 2017-03-21 | 2017-03-21 | Tétrahydrate de ligand h3, son procédé de préparation et compositions pharmaceutiques le comprenant |
| PCT/EP2018/056999 WO2018172344A1 (fr) | 2017-03-21 | 2018-03-20 | Tétrahydrate de ligand h3, son procédé de préparation et compositions pharmaceutiques les comprenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA48971A true MA48971A (fr) | 2020-02-05 |
| MA48971B1 MA48971B1 (fr) | 2021-03-31 |
Family
ID=58488932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA48971A MA48971B1 (fr) | 2017-03-21 | 2018-03-20 | Tétrahydrate de ligand h3, son procédé de préparation et compositions pharmaceutiques le comprenant |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11078183B2 (fr) |
| EP (2) | EP3378858A1 (fr) |
| JP (1) | JP7235671B2 (fr) |
| KR (1) | KR102608265B1 (fr) |
| CN (1) | CN110891948B (fr) |
| AU (1) | AU2018238260B2 (fr) |
| CA (1) | CA3056490A1 (fr) |
| CY (1) | CY1124114T1 (fr) |
| DK (1) | DK3601252T3 (fr) |
| ES (1) | ES2868024T3 (fr) |
| HR (1) | HRP20210312T1 (fr) |
| HU (1) | HUE053710T2 (fr) |
| IL (1) | IL269360B2 (fr) |
| LT (1) | LT3601252T (fr) |
| MA (1) | MA48971B1 (fr) |
| MX (1) | MX389167B (fr) |
| PL (1) | PL3601252T3 (fr) |
| PT (1) | PT3601252T (fr) |
| RS (1) | RS61511B1 (fr) |
| SM (1) | SMT202100278T1 (fr) |
| WO (1) | WO2018172344A1 (fr) |
| ZA (1) | ZA201906202B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3378477A1 (fr) * | 2017-03-21 | 2018-09-26 | BIOPROJET Pharma | Nouvelles utilisations thérapeutiques de ligands h3 |
| EP3598975B1 (fr) | 2018-07-27 | 2020-10-21 | Bioprojet | Nouvelles combinaisons d'un antagoniste h3 et un inhibiteur de la recapture de la noradrénaline et leurs utilisations thérapeutiques |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4464814B2 (ja) * | 2002-05-14 | 2010-05-19 | アバーント・ファーマシューティカルズ・（インディア）・リミテッド | アントラニル酸誘導体の水和物の製造方法 |
| CN101111480A (zh) * | 2004-12-01 | 2008-01-23 | 万有制药株式会社 | 取代的吡啶酮衍生物 |
| EP1717235A3 (fr) | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines et leur utilisation comme ligands du récepteur histaminique H3 |
| RU2618228C2 (ru) * | 2011-12-08 | 2017-05-03 | Тайсо Фармасьютикал Ко., Лтд. | Производное фенилпиррола |
| EP2799436A4 (fr) * | 2011-12-27 | 2015-07-01 | Taisho Pharmaceutical Co Ltd | Dérivé de phényltriazole |
| EP3378477A1 (fr) * | 2017-03-21 | 2018-09-26 | BIOPROJET Pharma | Nouvelles utilisations thérapeutiques de ligands h3 |
| EP3598975B1 (fr) * | 2018-07-27 | 2020-10-21 | Bioprojet | Nouvelles combinaisons d'un antagoniste h3 et un inhibiteur de la recapture de la noradrénaline et leurs utilisations thérapeutiques |
-
2017
- 2017-03-21 EP EP17305310.9A patent/EP3378858A1/fr not_active Withdrawn
-
2018
- 2018-03-20 AU AU2018238260A patent/AU2018238260B2/en active Active
- 2018-03-20 HR HRP20210312TT patent/HRP20210312T1/hr unknown
- 2018-03-20 KR KR1020197027549A patent/KR102608265B1/ko active Active
- 2018-03-20 LT LTEP18711350.1T patent/LT3601252T/lt unknown
- 2018-03-20 EP EP18711350.1A patent/EP3601252B1/fr active Active
- 2018-03-20 RS RS20210249A patent/RS61511B1/sr unknown
- 2018-03-20 CN CN201880028499.3A patent/CN110891948B/zh active Active
- 2018-03-20 MX MX2019011264A patent/MX389167B/es unknown
- 2018-03-20 DK DK18711350.1T patent/DK3601252T3/da active
- 2018-03-20 MA MA48971A patent/MA48971B1/fr unknown
- 2018-03-20 JP JP2019552006A patent/JP7235671B2/ja active Active
- 2018-03-20 WO PCT/EP2018/056999 patent/WO2018172344A1/fr not_active Ceased
- 2018-03-20 SM SM20210278T patent/SMT202100278T1/it unknown
- 2018-03-20 PT PT187113501T patent/PT3601252T/pt unknown
- 2018-03-20 US US16/496,013 patent/US11078183B2/en active Active
- 2018-03-20 CA CA3056490A patent/CA3056490A1/fr active Pending
- 2018-03-20 HU HUE18711350A patent/HUE053710T2/hu unknown
- 2018-03-20 ES ES18711350T patent/ES2868024T3/es active Active
- 2018-03-20 PL PL18711350T patent/PL3601252T3/pl unknown
-
2019
- 2019-09-15 IL IL269360A patent/IL269360B2/en unknown
- 2019-09-19 ZA ZA2019/06202A patent/ZA201906202B/en unknown
-
2021
- 2021-03-04 CY CY20211100186T patent/CY1124114T1/el unknown
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