DK3601252T3 - Tetrahydrat af H3-ligand, fremgangsmåde til fremstilling deraf og farma-ceutiske sammensætninger omfattende samme - Google Patents

Tetrahydrat af H3-ligand, fremgangsmåde til fremstilling deraf og farma-ceutiske sammensætninger omfattende samme Download PDF

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Publication number
DK3601252T3
DK3601252T3 DK18711350.1T DK18711350T DK3601252T3 DK 3601252 T3 DK3601252 T3 DK 3601252T3 DK 18711350 T DK18711350 T DK 18711350T DK 3601252 T3 DK3601252 T3 DK 3601252T3
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DK
Denmark
Prior art keywords
tetrahydrate
ligand
preparation
same
pharmaceutical compositions
Prior art date
Application number
DK18711350.1T
Other languages
English (en)
Inventor
Marc Capet
Jeanne-Marie Lecomte
Jean-Charles Schwartz
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Application granted granted Critical
Publication of DK3601252T3 publication Critical patent/DK3601252T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
DK18711350.1T 2017-03-21 2018-03-20 Tetrahydrat af H3-ligand, fremgangsmåde til fremstilling deraf og farma-ceutiske sammensætninger omfattende samme DK3601252T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17305310.9A EP3378858A1 (en) 2017-03-21 2017-03-21 Tetrahydrate of h3 ligand, its process of preparation and pharmaceutical compositions comprising the same
PCT/EP2018/056999 WO2018172344A1 (en) 2017-03-21 2018-03-20 Tetrahydrate of h3 ligand, its process of preparation and pharmaceutical compositions comprising the same

Publications (1)

Publication Number Publication Date
DK3601252T3 true DK3601252T3 (da) 2021-03-08

Family

ID=58488932

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18711350.1T DK3601252T3 (da) 2017-03-21 2018-03-20 Tetrahydrat af H3-ligand, fremgangsmåde til fremstilling deraf og farma-ceutiske sammensætninger omfattende samme

Country Status (23)

Country Link
US (1) US11078183B2 (da)
EP (2) EP3378858A1 (da)
JP (1) JP7235671B2 (da)
KR (1) KR102608265B1 (da)
CN (1) CN110891948B (da)
AU (1) AU2018238260B2 (da)
CA (1) CA3056490A1 (da)
CY (1) CY1124114T1 (da)
DK (1) DK3601252T3 (da)
ES (1) ES2868024T3 (da)
HR (1) HRP20210312T1 (da)
HU (1) HUE053710T2 (da)
IL (1) IL269360B2 (da)
LT (1) LT3601252T (da)
MA (1) MA48971B1 (da)
MX (1) MX389167B (da)
NZ (1) NZ757340A (da)
PL (1) PL3601252T3 (da)
PT (1) PT3601252T (da)
RS (1) RS61511B1 (da)
SM (1) SMT202100278T1 (da)
WO (1) WO2018172344A1 (da)
ZA (1) ZA201906202B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3378477A1 (en) * 2017-03-21 2018-09-26 BIOPROJET Pharma New therapeutical use of h3-ligands
HUE052652T2 (hu) 2018-07-27 2021-05-28 Bioprojet Soc Civ H3 antagonista és noradrenalin újrafelvétel-gátló új kombinációja, és terápiás alkalmazásai

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524861B2 (en) * 2002-05-14 2009-04-28 David Frank Hayman Process for the preparation of a hydrate of an anthranilic acid derivative
WO2006059778A1 (ja) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. 置換ピリドン誘導体
EP1717235A3 (en) 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
EP2789608A4 (en) 2011-12-08 2015-07-01 Taisho Pharmaceutical Co Ltd PHENYLPYRROLDERIVAT
TW201343636A (zh) 2011-12-27 2013-11-01 大正製藥股份有限公司 苯基三唑衍生物
EP3378477A1 (en) * 2017-03-21 2018-09-26 BIOPROJET Pharma New therapeutical use of h3-ligands
HUE052652T2 (hu) * 2018-07-27 2021-05-28 Bioprojet Soc Civ H3 antagonista és noradrenalin újrafelvétel-gátló új kombinációja, és terápiás alkalmazásai

Also Published As

Publication number Publication date
LT3601252T (lt) 2021-04-26
CY1124114T1 (el) 2022-05-27
EP3601252A1 (en) 2020-02-05
RS61511B1 (sr) 2021-03-31
RU2019129432A3 (da) 2021-07-01
IL269360B (en) 2022-10-01
JP2020511507A (ja) 2020-04-16
JP7235671B2 (ja) 2023-03-08
MA48971B1 (fr) 2021-03-31
IL269360A (en) 2019-11-28
US20200024256A1 (en) 2020-01-23
ES2868024T3 (es) 2021-10-21
EP3378858A1 (en) 2018-09-26
EP3601252B1 (en) 2021-02-17
US11078183B2 (en) 2021-08-03
HUE053710T2 (hu) 2021-07-28
AU2018238260A1 (en) 2019-10-10
CN110891948B (zh) 2022-11-11
KR20200008995A (ko) 2020-01-29
PT3601252T (pt) 2021-03-31
RU2019129432A (ru) 2021-03-18
BR112019019643A2 (pt) 2020-04-14
ZA201906202B (en) 2020-10-28
KR102608265B1 (ko) 2023-11-30
NZ757340A (en) 2026-03-27
IL269360B2 (en) 2023-02-01
AU2018238260B2 (en) 2021-07-22
WO2018172344A1 (en) 2018-09-27
MX389167B (es) 2025-03-20
MA48971A (fr) 2020-02-05
CA3056490A1 (en) 2018-09-27
HRP20210312T1 (hr) 2021-04-02
PL3601252T3 (pl) 2021-08-02
SMT202100278T1 (it) 2021-07-12
CN110891948A (zh) 2020-03-17

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