MA49257A - Anticorps anti-trkb - Google Patents
Anticorps anti-trkbInfo
- Publication number
- MA49257A MA49257A MA049257A MA49257A MA49257A MA 49257 A MA49257 A MA 49257A MA 049257 A MA049257 A MA 049257A MA 49257 A MA49257 A MA 49257A MA 49257 A MA49257 A MA 49257A
- Authority
- MA
- Morocco
- Prior art keywords
- trkb antibodies
- trkb
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17175122 | 2017-06-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49257A true MA49257A (fr) | 2020-04-15 |
Family
ID=59034551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049257A MA49257A (fr) | 2017-06-09 | 2018-06-08 | Anticorps anti-trkb |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10793634B2 (fr) |
| EP (1) | EP3635004A1 (fr) |
| JP (2) | JP7267208B2 (fr) |
| KR (1) | KR20200017421A (fr) |
| CN (1) | CN110719916B (fr) |
| AR (1) | AR112602A1 (fr) |
| AU (1) | AU2018279184B2 (fr) |
| BR (1) | BR112019023742A2 (fr) |
| CA (1) | CA3063965A1 (fr) |
| CL (1) | CL2019003557A1 (fr) |
| CO (1) | CO2019013718A2 (fr) |
| EA (1) | EA201992883A1 (fr) |
| IL (1) | IL271067B2 (fr) |
| MA (1) | MA49257A (fr) |
| MX (1) | MX2019014714A (fr) |
| MY (1) | MY202315A (fr) |
| PE (1) | PE20200173A1 (fr) |
| PH (1) | PH12019502694A1 (fr) |
| SG (1) | SG11201911814UA (fr) |
| TW (2) | TWI808086B (fr) |
| UA (1) | UA127967C2 (fr) |
| WO (1) | WO2018224630A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019022074A2 (pt) * | 2017-06-02 | 2020-05-12 | Boehringer Ingelheim International Gmbh | Terapia de combinação anticâncer |
| KR20220100925A (ko) | 2019-11-11 | 2022-07-18 | 베링거 인겔하임 인터내셔날 게엠베하 | Npy2 수용체 작용제 |
| WO2022029231A1 (fr) | 2020-08-07 | 2022-02-10 | Boehringer Ingelheim International Gmbh | Agonistes du récepteur npy2 solubles |
| TW202233668A (zh) | 2020-10-21 | 2022-09-01 | 德商百靈佳殷格翰國際股份有限公司 | 用於治療眼部疾病之雙特異性抗-VEGF及抗-TrkB結合分子 |
| WO2023125485A1 (fr) * | 2021-12-28 | 2023-07-06 | 4B Technologies (Beijing) Co., Limited | Anticorps trkb et son application |
| WO2025062271A1 (fr) * | 2023-09-19 | 2025-03-27 | Signorile Pietro Giulio | Anticorps dirigés contre l'endométriose |
| CN119841947B (zh) * | 2024-12-17 | 2026-04-17 | 河南农业大学 | 十二指肠贾第虫cwp2蛋白的单克隆抗体及配对单克隆抗体及应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| EP0206448B1 (fr) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hémoglobine liée à un poly(oxyde d'alkylène) |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| WO1990003430A1 (fr) | 1988-09-23 | 1990-04-05 | Cetus Corporation | Milieu de culture de cellules pour l'amelioration de la croissance des cellules, de la longivite de la culture et de l'expression du produit |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (fr) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Vecteurs de transformation de la levure yarrowia |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| WO1994004679A1 (fr) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Procede pour fabriquer des anticorps humanises |
| EP0590058B1 (fr) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | ANTICORP HUMANISE specifique pour heregulin |
| ATE139900T1 (de) | 1992-11-13 | 1996-07-15 | Idec Pharma Corp | Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| US6037454A (en) | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| MX2007015292A (es) | 2005-06-06 | 2008-02-21 | Wyeth Corp | Anticuerpos monoclonales anti-trkb y sus usos. |
| KR20090088896A (ko) * | 2006-11-09 | 2009-08-20 | 아이알엠 엘엘씨 | 효현제 trkb 항체 및 그의 용도 |
| CA2672750A1 (fr) | 2006-12-20 | 2008-07-03 | Rinat Neuroscience Corporation | Agonistes de trkb pour le traitement des troubles auto-immunitaires |
| CA2701189C (fr) * | 2007-10-11 | 2017-05-16 | Biogen Idec Ma Inc. | Methodes permettant de traiter la neuropathie optique induite par la pression, de prevenir la degenerescence des neurones et de favoriser la survie des neurones par l'administration d'antagonistes de lingo-1 et d'agonistes de trkb |
| KR20100089851A (ko) | 2007-10-23 | 2010-08-12 | 노파르티스 아게 | 호흡기 질환의 치료를 위한 trkb 항체의 용도 |
| JP5420568B2 (ja) * | 2008-01-17 | 2014-02-19 | アイアールエム・リミテッド・ライアビリティ・カンパニー | 改良された抗TrkB抗体 |
| BRPI0905955A8 (pt) * | 2008-02-04 | 2018-05-08 | Lay Line Genomics Spa | anticorpo ani trka, anticorpo ou derivado, derivado de um anticorpo, combinação de um anticorpo ou derivado, composição farmaceutica, método, polipetídeo, ácido nucléico codificante de um aniticorpo ou derivado do mesmo, vetor, sistema de expressão ,mamífero transgênico não humano e kit compreendo um anticorpo ou derivado |
| EP2318010A4 (fr) * | 2008-07-28 | 2014-05-21 | Univ Emory | Traitement de divers troubles mettant en oeuvre des agonistes trkb |
| WO2010086828A2 (fr) | 2009-02-02 | 2010-08-05 | Rinat Neuroscience Corporation | Anticorps monoclonaux agonistes anti-trkb |
| WO2011103667A1 (fr) * | 2010-02-26 | 2011-09-01 | 6452728 Canada Inc. | Anticorps agonistes des récepteurs trkb et leurs utilisations |
| US9029561B2 (en) | 2010-06-09 | 2015-05-12 | Emory University | TRKB agonists and methods of use |
| WO2012027821A1 (fr) | 2010-09-03 | 2012-03-08 | The Royal Institution For The Advancement Of Learning / Mcgill University | Anticorps agoniste de récepteur trkc pour traiter des maladies neurodégénératives et neuromotrices |
| GB2491106A (en) | 2011-05-18 | 2012-11-28 | Univ Basel | Antibodies against tropomyosin-related kinase B receptors |
| WO2015173756A2 (fr) | 2014-05-16 | 2015-11-19 | Pfizer Inc. | Anticorps bispécifiques |
| EP3328898B8 (fr) * | 2015-07-28 | 2024-04-10 | 6452728 Canada Corp. | Compositions d'agoniste trkb ou trkc et méthodes de traitement de troubles otiques |
| TW201730206A (zh) | 2015-11-17 | 2017-09-01 | 葛蘭素史克智慧財產發展有限公司 | 用於治療神經及其他疾病之結合激動劑 |
| KR102986081B1 (ko) | 2017-11-30 | 2026-07-06 | 리제너론 파아마슈티컬스, 인크. | 항-trkb 모노클로날 항체 및 이의 사용 방법 |
-
2018
- 2018-06-07 US US16/002,058 patent/US10793634B2/en active Active
- 2018-06-08 WO PCT/EP2018/065107 patent/WO2018224630A1/fr not_active Ceased
- 2018-06-08 JP JP2019567701A patent/JP7267208B2/ja active Active
- 2018-06-08 AU AU2018279184A patent/AU2018279184B2/en active Active
- 2018-06-08 PE PE2019002525A patent/PE20200173A1/es unknown
- 2018-06-08 MX MX2019014714A patent/MX2019014714A/es unknown
- 2018-06-08 CA CA3063965A patent/CA3063965A1/fr active Pending
- 2018-06-08 TW TW107119755A patent/TWI808086B/zh active
- 2018-06-08 MA MA049257A patent/MA49257A/fr unknown
- 2018-06-08 TW TW112123529A patent/TW202342100A/zh unknown
- 2018-06-08 AR ARP180101558 patent/AR112602A1/es unknown
- 2018-06-08 UA UAA201911908A patent/UA127967C2/uk unknown
- 2018-06-08 KR KR1020197037817A patent/KR20200017421A/ko not_active Withdrawn
- 2018-06-08 SG SG11201911814UA patent/SG11201911814UA/en unknown
- 2018-06-08 BR BR112019023742A patent/BR112019023742A2/pt unknown
- 2018-06-08 EP EP18731764.9A patent/EP3635004A1/fr active Pending
- 2018-06-08 IL IL271067A patent/IL271067B2/en unknown
- 2018-06-08 EA EA201992883A patent/EA201992883A1/ru unknown
- 2018-06-08 MY MYPI2019007297A patent/MY202315A/en unknown
- 2018-06-08 CN CN201880038098.6A patent/CN110719916B/zh active Active
-
2019
- 2019-11-28 PH PH12019502694A patent/PH12019502694A1/en unknown
- 2019-12-05 CL CL2019003557A patent/CL2019003557A1/es unknown
- 2019-12-05 CO CONC2019/0013718A patent/CO2019013718A2/es unknown
-
2020
- 2020-08-26 US US17/002,907 patent/US11866501B2/en active Active
-
2023
- 2023-04-19 JP JP2023068735A patent/JP7505084B2/ja active Active
- 2023-11-28 US US18/520,650 patent/US20240101689A1/en not_active Abandoned
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