|
FR2585572B3
(fr)
|
1985-07-31 |
1987-12-31 |
Hugelin Andre |
Nouvelles compositions pharmaceutiques a base d'un sel de l'acide p. chlorophenoxyacetique destinees au traitement des neuropathies et assurant la regeneration nerveuse
|
|
US6429207B1
(en)
|
1997-11-21 |
2002-08-06 |
Nps Pharmaceuticals, Inc. |
Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
|
|
ES2221440T3
(es)
|
1998-10-16 |
2004-12-16 |
Daiichi Suntory Pharma Co Ltd |
Derivados de acido aminofenoxiacetico como neuroprotectores.
|
|
AR024077A1
(es)
|
1999-05-25 |
2002-09-04 |
Smithkline Beecham Corp |
Compuestos antibacterianos
|
|
AU2001249417A1
(en)
|
2000-04-26 |
2001-11-07 |
Gliatech, Inc. |
Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives
|
|
CA2443108A1
(fr)
|
2001-04-03 |
2002-10-17 |
Merck & Co. Inc. |
Antagonistes de nmda/nr2b nonaryl-heterocyclo amidyle n-substitues
|
|
JO2397B1
(en)
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
|
CN101068794B
(zh)
|
2004-09-02 |
2012-12-19 |
沃泰克斯药物股份有限公司 |
可用作离子通道调控剂的喹唑啉
|
|
CA2580621A1
(fr)
|
2004-09-24 |
2006-03-30 |
Actelion Pharmaceuticals Ltd |
Nouveaux antibiotiques bicycliques
|
|
WO2006125974A1
(fr)
|
2005-05-24 |
2006-11-30 |
Astrazeneca Ab |
Quinoleines d’aminopiperidine et leurs analogues azaisosteriques presentant une activite antibacterienne
|
|
SG170767A1
(en)
|
2005-12-23 |
2011-05-30 |
Zealand Pharma As |
Modified lysine-mimetic compounds
|
|
US20080221100A1
(en)
|
2006-10-20 |
2008-09-11 |
Arete Therapeutics, Inc. |
Soluble epoxide hydrolase inhibitors
|
|
JP5274553B2
(ja)
|
2007-06-15 |
2013-08-28 |
アクテリオン ファーマシューティカルズ リミテッド |
３−アミノ−６−（１−アミノ−エチル）−テトラヒドロピラン誘導体
|
|
NZ593891A
(en)
|
2008-12-12 |
2013-05-31 |
Actelion Pharmaceuticals Ltd |
5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
|
|
AU2010253820A1
(en)
|
2009-05-28 |
2011-12-22 |
President And Fellows Of Harvard College |
N,N-diarylurea compounds and N,N'-diarylthiourea compounds as inhibitors of translation initiation
|
|
GEAP202213376A
(en)
|
2009-06-17 |
2022-02-25 |
Vertex Pharmaceuticals Incorporated Us |
Inhibitors of influenza viruses replication
|
|
EA024026B1
(ru)
|
2010-11-25 |
2016-08-31 |
Рациофарм Гмбх |
Новые соли и полиморфные формы афатиниба
|
|
AR084457A1
(es)
|
2010-12-22 |
2013-05-15 |
Lundbeck & Co As H |
Derivados de biciclo[3,2,1]octilamida
|
|
CN103403002B
(zh)
|
2011-02-24 |
2016-06-22 |
内尔维阿诺医学科学有限公司 |
作为激酶抑制剂的噻唑基苯基-苯磺酰氨基衍生物
|
|
DK2684880T3
(en)
|
2011-03-10 |
2018-05-22 |
Daiichi Sankyo Co Ltd |
DISPIROPYRROLIDINE DERIVATIVES
|
|
AU2012245387C1
(en)
|
2011-04-22 |
2016-05-05 |
Signal Pharmaceuticals, Llc |
Substituted Diaminocarboxamide and Diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
|
|
WO2013058448A1
(fr)
|
2011-10-20 |
2013-04-25 |
한국해양연구원 |
Gènes de medaka marin répondant à l'exposition à des substances chimiques perturbant le système endocrinien et procédé destiné à diagnostiquer une pollution d'un écosystème aquatique les utilisant
|
|
EP2814321B1
(fr)
*
|
2012-02-14 |
2018-09-26 |
Syngenta Participations AG |
Dérivés de cis(hétéro)arylcyclopropylcarboxamide utiles en tant que nematicides
|
|
CN104837820A
(zh)
|
2012-10-02 |
2015-08-12 |
大日本住友制药株式会社 |
咪唑衍生物
|
|
KR102243637B1
(ko)
|
2013-03-14 |
2021-04-26 |
리커리엄 아이피 홀딩스, 엘엘씨 |
바이사이클릭 진통 화합물
|
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
CA2904794C
(fr)
|
2013-03-15 |
2021-11-23 |
Peter Walter |
Modulateurs de la voie eif2 alpha
|
|
WO2015038778A1
(fr)
|
2013-09-11 |
2015-03-19 |
The Brigham And Women's Hospital, Inc. |
Activateurs substitués de l'urée-kinase eif2α
|
|
LT3126352T
(lt)
|
2014-04-04 |
2019-01-10 |
Syros Pharmaceuticals, Inc. |
Nuo ciklino priklausomos kinazės 7 (cdk7) inhibitoriai
|
|
WO2016044331A1
(fr)
|
2014-09-17 |
2016-03-24 |
Kalyra Pharmaceuticals, Inc. |
Composés bicycliques
|
|
WO2016059453A1
(fr)
|
2014-10-16 |
2016-04-21 |
Fundacion Fraunhofer Chile Research |
Biomarqueurs et cibles thérapeutiques pour la maladie d'alzheimer
|
|
NZ730728A
(en)
|
2014-11-20 |
2022-04-29 |
Merck Patent Gmbh |
Heteroaryl compounds as irak inhibitors and uses thereof
|
|
EP3233087B1
(fr)
*
|
2014-12-16 |
2019-10-02 |
Axovant Sciences GmbH |
Composés amide de quinuclidine à substituants géminal, en tant qu'agonistes des récepteurs nicotiniques de l'acétylcholine 7
|
|
KR20170137725A
(ko)
|
2015-02-25 |
2017-12-13 |
윌리엄 마쉬 라이스 유니버시티 |
데스아세톡시투불리신 h 및 이의 유사체
|
|
GB201506894D0
(en)
|
2015-04-23 |
2015-06-10 |
Galapagos Nv |
Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders
|
|
CA2984848A1
(fr)
|
2015-05-05 |
2016-11-10 |
Bayer Pharma Aktiengesellschaft |
Derives de cyclohexane a substitution amido
|
|
TW201718557A
(zh)
|
2015-10-08 |
2017-06-01 |
歌林達有限公司 |
經吡唑基取代之四氫吡喃基碸
|
|
TWI844006B
(zh)
|
2016-05-05 |
2024-06-01 |
美商嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
TW201808903A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
TW201808914A
(zh)
*
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
|
KR20190015748A
(ko)
|
2016-06-08 |
2019-02-14 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
Atf4 경로 억제제로서의 화학적 화합물
|
|
US10851053B2
(en)
|
2016-06-08 |
2020-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
TWI749024B
(zh)
|
2016-07-06 |
2021-12-11 |
美商艾克奎斯特有限責任公司 |
化合物及其於降低尿酸位準之用途
|
|
JOP20190072A1
(ar)
|
2016-10-13 |
2019-04-07 |
Glaxosmithkline Ip Dev Ltd |
مشتقات 1، 3 سيكلوبوتان ثنائي الاستبدال أو آزيتيدين كمثبطات للإنزيم المخلق للبروستاجلاندين d المكون للدم
|
|
US10093664B2
(en)
|
2016-12-08 |
2018-10-09 |
Board Of Regents, The University Of Texas System |
Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease
|
|
WO2018225093A1
(fr)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Composés chimiques utilisés comme inhibiteurs de la voie atf4
|
|
KR102615098B1
(ko)
|
2017-06-09 |
2023-12-18 |
브리스톨-마이어스 스큅 컴퍼니 |
시클로프로필 우레아 포르밀 펩티드 2 수용체 및 포르밀 펩티드 1 수용체 효능제
|
|
BR112020000122A2
(pt)
|
2017-07-03 |
2020-07-07 |
Glaxosmithkline Intellectual Property Development Limited |
derivados da n-(3-(2-(4-clorofenóxi)acetamido)biciclo[1.1.1] pentan-1-il)-2-ciclobutano-1-carboxamida e compostos relacionados como inibidores do atf4 para tratamento contra o câncer e outras doenças
|
|
CA3068395A1
(fr)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
Derives de 2-(4-chlorophenoxy)-n-((1-(2-(4-chlorophenoxy)ethynazetidine-3-yl)methyl)acetamide et composes apparentes servant d'inhibiteurs d'atf4 pour le traitement du cancer et d'autres maladies
|
|
MA49858A
(fr)
|
2017-08-09 |
2021-04-28 |
Denali Therapeutics Inc |
Composés, compositions et procédés
|
|
DK3676297T3
(da)
|
2017-09-01 |
2023-08-14 |
Denali Therapeutics Inc |
Forbindelser, sammensætninger og fremgangsmåder
|
|
WO2019054430A1
(fr)
|
2017-09-14 |
2019-03-21 |
第一三共株式会社 |
Composé amide ayant un hétérocycle aromatique
|
|
CA3080808A1
(fr)
|
2017-11-02 |
2019-05-09 |
Calico Life Sciences Llc |
Modulateurs de la voie de reponse integree au stress
|
|
KR20200092332A
(ko)
|
2017-11-02 |
2020-08-03 |
칼리코 라이프 사이언시스 엘엘씨 |
통합된 스트레스 경로의 조절제
|
|
SG11202004009TA
(en)
|
2017-11-02 |
2020-05-28 |
Calico Life Sciences Llc |
Modulators of the integrated stress pathway
|
|
UY37957A
(es)
|
2017-11-02 |
2019-05-31 |
Abbvie Inc |
Moduladores de la vía de estrés integrada
|
|
CA3080971A1
(fr)
|
2017-11-02 |
2019-05-09 |
Calico Life Sciences Llc |
Modulateurs de la voie de reponse integree au stress
|
|
CA3080964A1
(fr)
|
2017-11-02 |
2019-05-09 |
Calico Life Sciences Llc |
Modulateurs de la voie de reponse integree au stress
|
|
UY37958A
(es)
|
2017-11-02 |
2019-05-31 |
Abbvie Inc |
Moduladores de la vía de estrés integrada
|
|
CN112218869A
(zh)
|
2017-11-02 |
2021-01-12 |
卡里科生命科学有限责任公司 |
整合应激通路的调节剂
|
|
UY37956A
(es)
|
2017-11-02 |
2019-05-31 |
Abbvie Inc |
Moduladores de la vía de estrés integrada
|
|
EP3723762A4
(fr)
|
2017-12-13 |
2021-12-08 |
Praxis Biotech LLC |
Inhibiteurs de la voie de réponse intégrée au stress
|
|
WO2019183589A1
(fr)
|
2018-03-23 |
2019-09-26 |
Denali Therapeutics Inc. |
Modulateurs du facteur 2 d'initiation eucaryote
|
|
WO2019193541A1
(fr)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Dérivés de cycle aromatiques bicycliques de formule (i) utilisés en tant qu'inhibiteurs d'atf4
|
|
WO2019193540A1
(fr)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Dérivés hétéroaryles de formule (i) utilisés en tant qu'inhibiteurs d'atf4
|
|
EP3820843A1
(fr)
|
2018-07-09 |
2021-05-19 |
GlaxoSmithKline Intellectual Property Development Limited |
Composés chimiques
|
|
WO2020031107A1
(fr)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Composés chimiques
|
|
TWI832295B
(zh)
|
2018-10-11 |
2024-02-11 |
美商嘉來克生命科學有限責任公司 |
整合應激路徑之前藥調節劑
|
|
SG11202108552QA
(en)
|
2019-02-13 |
2021-09-29 |
Denali Therapeutics Inc |
Compounds, compositions and methods
|
|
US20220177456A1
(en)
|
2019-03-06 |
2022-06-09 |
Denali Therapeutics Inc. |
Compounds, compositions and methods
|
|
IL287379B2
(en)
|
2019-04-23 |
2025-11-01 |
Evotec Int Gmbh |
Modulators of the integrated stress response pathway
|
|
KR20220016467A
(ko)
|
2019-04-30 |
2022-02-09 |
칼리코 라이프 사이언시스 엘엘씨 |
통합된 스트레스 경로의 조절인자로서 치환된 사이클로알킬
|
|
US20200347043A1
(en)
|
2019-04-30 |
2020-11-05 |
Calico Life Sciences Llc |
Modulators of the integrated stress pathway
|
|
US20230125481A1
(en)
|
2020-01-28 |
2023-04-27 |
Evotec International Gmbh |
Modulators of the integrated stress response pathway
|
|
CR20230254A
(es)
|
2020-12-18 |
2023-07-26 |
Denali Therapeutics Inc |
Formas sólidas de un compuesto
|
|
KR20250028345A
(ko)
|
2022-06-23 |
2025-02-28 |
데날리 테라퓨틱스 인크. |
진핵생물 개시 인자 2b의 조절제를 제조하는 공정
|