MA51418A - Inhibiteurs de glycolate oxydase pour le traitement de maladies - Google Patents

Inhibiteurs de glycolate oxydase pour le traitement de maladies

Info

Publication number
MA51418A
MA51418A MA051418A MA51418A MA51418A MA 51418 A MA51418 A MA 51418A MA 051418 A MA051418 A MA 051418A MA 51418 A MA51418 A MA 51418A MA 51418 A MA51418 A MA 51418A
Authority
MA
Morocco
Prior art keywords
diseases
treatment
oxidase inhibitors
glycolate oxidase
glycolate
Prior art date
Application number
MA051418A
Other languages
English (en)
Inventor
Qi Chao
Bing Wang
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of MA51418A publication Critical patent/MA51418A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA051418A 2017-12-29 2018-12-28 Inhibiteurs de glycolate oxydase pour le traitement de maladies MA51418A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762611995P 2017-12-29 2017-12-29
US201862765313P 2018-08-20 2018-08-20

Publications (1)

Publication Number Publication Date
MA51418A true MA51418A (fr) 2020-11-04

Family

ID=65234672

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051418A MA51418A (fr) 2017-12-29 2018-12-28 Inhibiteurs de glycolate oxydase pour le traitement de maladies

Country Status (17)

Country Link
US (3) US11384055B2 (fr)
EP (1) EP3732167A2 (fr)
JP (2) JP7344878B2 (fr)
KR (1) KR20200112860A (fr)
CN (6) CN111788187A (fr)
AR (1) AR114070A1 (fr)
AU (1) AU2018395275A1 (fr)
BR (1) BR112020013073A2 (fr)
CA (1) CA3086401A1 (fr)
CL (1) CL2020001742A1 (fr)
IL (3) IL297788A (fr)
MA (1) MA51418A (fr)
MX (6) MX2020006414A (fr)
PE (1) PE20201500A1 (fr)
SG (1) SG11202005807QA (fr)
TW (2) TWI811282B (fr)
WO (1) WO2019133770A2 (fr)

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* Cited by examiner, † Cited by third party
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AR114070A1 (es) * 2017-12-29 2020-07-15 Biomarin Pharm Inc Inhibidores de glicolato oxidasa para el tratamiento de una enfermedad
WO2019165159A1 (fr) 2018-02-23 2019-08-29 Oxalurx, Inc. Composés et méthodes de traitement de maladies liées à l'oxalate
PE20210859A1 (es) * 2018-07-06 2021-05-18 Orfan Biotech Inc Inhibidores de triazol glicolato oxidasa
CN114980886B (zh) 2019-08-22 2024-08-09 奥沙鲁克斯公司 用于治疗草酸盐相关疾病的化合物和方法
CN120381447A (zh) 2019-11-01 2025-07-29 紫丁香疗法有限公司 作为乙醇酸氧化酶抑制剂的杂环羧酸酯化合物
ES3049309T3 (en) * 2020-01-08 2025-12-16 Cantero Therapeutics Inc Processes for preparing triazole glycolate oxidase inhibitors
CN115702146B (zh) * 2020-06-30 2024-10-18 苏州恩华生物医药科技有限公司 5-((1,2,3,4-四氢异喹啉-7-基)氨基)吡啶-2(1h)-酮衍生物及其应用
IL300285A (en) 2020-08-04 2023-04-01 Calcilytix Therapeutics Inc Formulations of triphenyl calcilytic compounds
WO2022066933A1 (fr) * 2020-09-24 2022-03-31 Chinook Therapeutics Canada, Inc. Composés triazolyl substitués de pentafluoro-sulfanyl et procédés d'utilisation associés
CN114478210A (zh) * 2022-02-26 2022-05-13 江苏壹药新材料有限公司 一种7-氯萘-2-甲醛的合成方法
WO2023170024A1 (fr) * 2022-03-11 2023-09-14 University Of Copenhagen Modulateurs de camk2 et leur utilisation en médecine
GB202213162D0 (en) 2022-09-08 2022-10-26 Cambridge Entpr Ltd Prodrugs
WO2024109917A1 (fr) * 2022-11-25 2024-05-30 西藏海思科制药有限公司 Dérivé de triazole et son application en médecine
WO2024212137A1 (fr) * 2023-04-12 2024-10-17 Cantero Therapeutics, Inc. Formes cristallines d'un composé d'acide 1h-1, 2, 3-triazole-4-carboxylique
WO2025206002A1 (fr) * 2024-03-28 2025-10-02 日本曹達株式会社 Composé de triazole et microbicide pour une utilisation agricole ou horticole

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AR114070A1 (es) * 2017-12-29 2020-07-15 Biomarin Pharm Inc Inhibidores de glicolato oxidasa para el tratamiento de una enfermedad
EP3986863A4 (fr) * 2019-06-19 2023-01-18 BioMarin Pharmaceutical Inc. Inhibiteurs de glycolate oxydase pour le traitement d'une maladie

Also Published As

Publication number Publication date
CN117126152A (zh) 2023-11-28
US20230089374A1 (en) 2023-03-23
TW202340155A (zh) 2023-10-16
WO2019133770A3 (fr) 2019-08-15
BR112020013073A2 (pt) 2020-12-01
CN117024420A (zh) 2023-11-10
PE20201500A1 (es) 2020-12-29
WO2019133770A2 (fr) 2019-07-04
TW201930272A (zh) 2019-08-01
MX2022016434A (es) 2023-01-30
EP3732167A2 (fr) 2020-11-04
MX2022016463A (es) 2023-02-01
JP7344878B2 (ja) 2023-09-14
US11384055B2 (en) 2022-07-12
JP2021509401A (ja) 2021-03-25
SG11202005807QA (en) 2020-07-29
IL275496A (en) 2020-08-31
CL2020001742A1 (es) 2021-01-29
US20230079913A1 (en) 2023-03-16
CA3086401A1 (fr) 2019-07-04
MX2022016427A (es) 2023-01-30
KR20200112860A (ko) 2020-10-05
RU2020120974A (ru) 2022-01-31
MX2020006414A (es) 2020-09-17
MX2022016422A (es) 2023-01-30
CN117069712A (zh) 2023-11-17
RU2020120974A3 (fr) 2022-01-31
US20210171474A1 (en) 2021-06-10
MX2022016415A (es) 2023-01-30
CN111788187A (zh) 2020-10-16
CN117126151A (zh) 2023-11-28
AU2018395275A1 (en) 2020-07-16
IL297788A (en) 2022-12-01
IL297802A (en) 2022-12-01
JP2023159181A (ja) 2023-10-31
TWI811282B (zh) 2023-08-11
CN117069713A (zh) 2023-11-17
AR114070A1 (es) 2020-07-15

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