MA52365A - Composés et leurs utilisations - Google Patents

Composés et leurs utilisations

Info

Publication number
MA52365A
MA52365A MA052365A MA52365A MA52365A MA 52365 A MA52365 A MA 52365A MA 052365 A MA052365 A MA 052365A MA 52365 A MA52365 A MA 52365A MA 52365 A MA52365 A MA 52365A
Authority
MA
Morocco
Prior art keywords
compounds
Prior art date
Application number
MA052365A
Other languages
English (en)
Inventor
Bertrand Le Bourdonnec
Matthew Lucas
Kerem Ozboya
Bhaumik Pandya
Daniel Tardiff
Parcharee Tivitmahaisoon
Iwona Wrona
Original Assignee
Yumanity Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yumanity Therapeutics Inc filed Critical Yumanity Therapeutics Inc
Publication of MA52365A publication Critical patent/MA52365A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA052365A 2018-04-25 2019-04-24 Composés et leurs utilisations MA52365A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862662673P 2018-04-25 2018-04-25

Publications (1)

Publication Number Publication Date
MA52365A true MA52365A (fr) 2021-03-03

Family

ID=68290767

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052365A MA52365A (fr) 2018-04-25 2019-04-24 Composés et leurs utilisations

Country Status (6)

Country Link
US (1) US10919885B2 (fr)
EP (1) EP3784234A1 (fr)
JP (1) JP2021522253A (fr)
CN (1) CN112566636A (fr)
MA (1) MA52365A (fr)
WO (1) WO2019209962A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA46589A (fr) 2016-10-24 2019-08-28 Yumanity Therapeutics Inc Composés et utilisations de ces derniers
EP3566055B1 (fr) 2017-01-06 2025-03-12 Janssen Pharmaceutica NV Inhibiteurs de la scd pour le traitement de troubles neurologiques
CA3083000A1 (fr) 2017-10-24 2019-05-02 Yumanity Therapeutics, Inc. Composes et utilisations de ces composes
ES3043183T3 (en) 2018-03-23 2025-11-25 Janssen Pharmaceutica Nv Compounds and uses thereof
KR20210028144A (ko) 2018-04-06 2021-03-11 블랙 벨트 티엑스 리미티드 Atf6 저해제 및 그의 용도
MX2021008903A (es) 2019-01-24 2021-11-04 Yumanity Therapeutics Inc Compuestos y usos de los mismos.
JP2022552231A (ja) * 2019-10-09 2022-12-15 プラクシス バイオテック エルエルシー Atf6モジュレーターおよびその使用
CA3157173A1 (fr) * 2019-10-09 2021-04-15 Praxis Biotech LLC Modulateurs atf6 et leurs utilisations
WO2021092057A1 (fr) * 2019-11-04 2021-05-14 The Regents Of The University Of California Contrôle de l'hémodynamique activé par l'intelligence artificielle chez des patients en chirurgie
EA202192047A1 (ru) 2019-11-13 2021-12-08 Юманити Терапьютикс, Инк. Соединения и их применение
MX2023002224A (es) 2020-09-03 2023-03-15 Hoffmann La Roche Compuestos heterociclicos.
JP2024521618A (ja) * 2021-04-23 2024-06-04 エフ. ホフマン-ラ ロシュ アーゲー 複素環式化合物
CA3219022A1 (fr) * 2021-05-21 2022-11-24 Barbara Nave Utilisation de composes d'ethynylpyridine en tant qu'inhibiteurs de nitrification
DK4514782T3 (da) 2022-05-19 2025-12-15 Astrazeneca Ab Heteroaromatiske amidoforbindelser, der er nyttige ved behandling af leversygdomme

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003264018A1 (en) 2002-08-09 2004-02-25 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
CN1898235A (zh) 2003-12-24 2007-01-17 普罗西迪恩有限公司 作为gpcr受体激动剂的杂环衍生物
ES2325836T3 (es) 2004-07-26 2009-09-21 Merck Serono Sa Derivados de la n.hidroxiamida y uso de los mismos.
CA2580855A1 (fr) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Derives heterocycliques et leur utilisation en tant qu'agents therapeutiques
WO2006034341A2 (fr) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Derives heterocycliques et leur utilisation en tant qu'agents therapeutiques
WO2006130986A1 (fr) 2005-06-09 2006-12-14 Merck Frosst Canada Ltd. Derives d'azacyclohexane comme inhibiteurs de la stearoyl-coenzyme a delta-9 desaturase
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
JP2009539884A (ja) 2006-06-12 2009-11-19 メルク フロスト カナダ リミテツド ステアロイル−コエンザイムaデルタ−9デサチュラーゼのインヒビターとしてのアゼチジン誘導体
MX2009006728A (es) * 2006-12-20 2009-09-09 Novartis Ag Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd.
AU2008302570B2 (en) 2007-09-20 2012-05-31 Irm Llc Compounds and compositions as modulators of GPR119 activity
GB0722077D0 (en) 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
US8642660B2 (en) * 2007-12-21 2014-02-04 The University Of Rochester Method for altering the lifespan of eukaryotic organisms
MX2010010241A (es) 2008-03-20 2010-12-06 Forest Lab Holdings Ltd Derivados de piperidina novedosos como inhibidores de estearoil-coa desaturasa.
TWI434842B (zh) 2008-07-14 2014-04-21 Astellas Pharma Inc Azole compounds
WO2010022055A2 (fr) 2008-08-20 2010-02-25 Amgen Inc. Inhibiteurs de canaux sodiques sensibles au potentiel
WO2010039186A2 (fr) 2008-09-23 2010-04-08 Renovis, Inc. Composés utiles en tant que modulateurs de la faah et leurs utilisations
WO2010108268A1 (fr) 2009-03-23 2010-09-30 Merck Frosst Canada Ltd. Composés hétérocycliques inhibiteurs de la stéaroyl-coenzyme a delta-9 désaturase
US8563539B2 (en) 2009-12-23 2013-10-22 Jasco Pharmaceuticals, LLC Aminopyrimidine kinase inhibitors
US20150051206A1 (en) 2011-09-01 2015-02-19 Irm Llc Compounds and compositions as c-kit kinase inhibitors
MX2014004426A (es) 2011-10-15 2014-07-09 Genentech Inc Metodos de uso de antagonistas de scd1.
US20130225529A1 (en) 2012-02-27 2013-08-29 Basil Rigas Phospho-ester derivatives and uses thereof
WO2014057435A1 (fr) 2012-10-10 2014-04-17 Actelion Pharmaceuticals Ltd Antagonistes des récepteurs de l'orexine, qui sont des dérivés [ortho bi (hetero )aryl]-[2-(meta bi (hetero )aryl)-pyrrolidin-1-yl]-methanone
US10350192B2 (en) * 2015-02-09 2019-07-16 National University Corporation Okayama University Lactate dehydrogenase inhibitor and antiepileptic drug containing the same
MA46589A (fr) 2016-10-24 2019-08-28 Yumanity Therapeutics Inc Composés et utilisations de ces derniers

Also Published As

Publication number Publication date
US20190330198A1 (en) 2019-10-31
CN112566636A (zh) 2021-03-26
EP3784234A1 (fr) 2021-03-03
JP2021522253A (ja) 2021-08-30
WO2019209962A1 (fr) 2019-10-31
WO2019209962A8 (fr) 2020-04-09
US10919885B2 (en) 2021-02-16

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