MA52365A - Composés et leurs utilisations - Google Patents

Composés et leurs utilisations

Info

Publication number
MA52365A
MA52365A MA052365A MA52365A MA52365A MA 52365 A MA52365 A MA 52365A MA 052365 A MA052365 A MA 052365A MA 52365 A MA52365 A MA 52365A MA 52365 A MA52365 A MA 52365A
Authority
MA
Morocco
Prior art keywords
compounds
Prior art date
Application number
MA052365A
Other languages
English (en)
Inventor
Bertrand Le Bourdonnec
Matthew Lucas
Kerem Ozboya
Bhaumik Pandya
Daniel Tardiff
Parcharee Tivitmahaisoon
Iwona Wrona
Original Assignee
Yumanity Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yumanity Therapeutics Inc filed Critical Yumanity Therapeutics Inc
Publication of MA52365A publication Critical patent/MA52365A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA052365A 2018-04-25 2019-04-24 Composés et leurs utilisations MA52365A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862662673P 2018-04-25 2018-04-25

Publications (1)

Publication Number Publication Date
MA52365A true MA52365A (fr) 2021-03-03

Family

ID=68290767

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052365A MA52365A (fr) 2018-04-25 2019-04-24 Composés et leurs utilisations

Country Status (6)

Country Link
US (1) US10919885B2 (fr)
EP (1) EP3784234A1 (fr)
JP (1) JP2021522253A (fr)
CN (1) CN112566636A (fr)
MA (1) MA52365A (fr)
WO (1) WO2019209962A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019533022A (ja) 2016-10-24 2019-11-14 ユマニティ セラピューティクス,インコーポレーテッド 化合物及びその使用
CA3049010A1 (fr) 2017-01-06 2018-07-12 Yumanity Therapeutics, Inc. Methodes de traitement de troubles neurologiques
CA3083000A1 (fr) 2017-10-24 2019-05-02 Yumanity Therapeutics, Inc. Composes et utilisations de ces composes
CA3094527A1 (fr) 2018-03-23 2019-09-26 Yumanity Therapeutics, Inc. Composes et leurs utilisations
EP3774782A2 (fr) 2018-04-06 2021-02-17 Black Belt TX Ltd Inhibiteurs d'atf6 et leurs utilisations
US12098146B2 (en) 2019-01-24 2024-09-24 Janssen Pharmaceutica Nv Compounds and uses thereof
CN119751439A (zh) * 2019-10-09 2025-04-04 阿尔托斯实验室公司 Atf6调节剂及其用途
CN119823112A (zh) * 2019-10-09 2025-04-15 阿尔托斯实验室公司 Atf6调节剂及其用途
US20220406429A1 (en) * 2019-11-04 2022-12-22 The Regents Of The University Of California Artificial Intelligence Enabled Control of Hemodynamics in Surgery Patients
EA202192047A1 (ru) 2019-11-13 2021-12-08 Юманити Терапьютикс, Инк. Соединения и их применение
CR20230115A (es) 2020-09-03 2023-04-11 Hoffmann La Roche Compuestos heterocíclicos
KR20240000574A (ko) * 2021-04-23 2024-01-02 에프. 호프만-라 로슈 아게 헤테로시클릭 화합물
EP4341245A1 (fr) * 2021-05-21 2024-03-27 Basf Se Utilisation de composés d'éthynylpyridine en tant qu'inhibiteurs de nitrification
EP4514782B1 (fr) 2022-05-19 2025-09-10 Astrazeneca AB Composés amido hétéroaromatiques utiles dans le traitement de maladies hépatiques

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004014902A2 (fr) 2002-08-09 2004-02-19 Astrazeneca Ab Nouveaux composes
BRPI0418149A (pt) 2003-12-24 2007-04-17 Prosidion Ltd derivados heterocìclicos como agonistas do receptor de gprc
ES2325836T3 (es) 2004-07-26 2009-09-21 Merck Serono Sa Derivados de la n.hidroxiamida y uso de los mismos.
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
MX2007003319A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
CA2610196A1 (fr) 2005-06-09 2006-12-14 Merck Frosst Canada Ltd. Derives d'azacyclohexane comme inhibiteurs de la stearoyl-coenzyme a delta-9 desaturase
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
CA2654792A1 (fr) 2006-06-12 2007-12-21 Merck Frosst Canada Ltd. Derives d'azetidine comme inhibiteurs de la stearoyl-coenzyme a delta-9 desaturase
EP2121671A1 (fr) * 2006-12-20 2009-11-25 Novartis AG Hétérocycles à 5 chaînons substitués en position 2 comme inhibiteurs de scd
CA2697551C (fr) 2007-09-20 2013-03-12 Irm Llc Composes et compositions en tant que modulateurs de l'activite de gpr119
GB0722077D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
US8642660B2 (en) * 2007-12-21 2014-02-04 The University Of Rochester Method for altering the lifespan of eukaryotic organisms
KR20100134680A (ko) 2008-03-20 2010-12-23 포레스트 래보러토리즈 홀딩스 리미티드 스테아로일-coa 불포화효소의 저해물질로서 신규한 피페리딘 유도체
TWI434842B (zh) 2008-07-14 2014-04-21 Astellas Pharma Inc Azole compounds
WO2010022055A2 (fr) 2008-08-20 2010-02-25 Amgen Inc. Inhibiteurs de canaux sodiques sensibles au potentiel
WO2010039186A2 (fr) 2008-09-23 2010-04-08 Renovis, Inc. Composés utiles en tant que modulateurs de la faah et leurs utilisations
US20120010186A1 (en) 2009-03-23 2012-01-12 Merck Frosst Canada Ltd. Heterocyclic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
BR112012015248B1 (pt) 2009-12-23 2022-01-04 Jasco Pharmaceuticals, LLC Composto
BR112014003963A2 (pt) 2011-09-01 2017-03-21 Irm Llc compostos e composições como inibidores de quinase c-kit
MX2014004426A (es) 2011-10-15 2014-07-09 Genentech Inc Metodos de uso de antagonistas de scd1.
US20130225529A1 (en) 2012-02-27 2013-08-29 Basil Rigas Phospho-ester derivatives and uses thereof
AU2013328301A1 (en) 2012-10-10 2015-05-28 Actelion Pharmaceuticals Ltd Orexin receptor antagonists which are [ortho bi (hetero-)aryl]-[2-(meta bi (hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives
EP3257510B1 (fr) * 2015-02-09 2021-10-20 National University Corporation Okayama University Inhibiteur de la lactate déshydrogénase et médicament antiépileptique le contenant
JP2019533022A (ja) 2016-10-24 2019-11-14 ユマニティ セラピューティクス,インコーポレーテッド 化合物及びその使用

Also Published As

Publication number Publication date
CN112566636A (zh) 2021-03-26
JP2021522253A (ja) 2021-08-30
EP3784234A1 (fr) 2021-03-03
US10919885B2 (en) 2021-02-16
US20190330198A1 (en) 2019-10-31
WO2019209962A1 (fr) 2019-10-31
WO2019209962A8 (fr) 2020-04-09

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