MA52587A - Composés d'azabenzimidazole et produit pharmaceutique - Google Patents

Composés d'azabenzimidazole et produit pharmaceutique

Info

Publication number
MA52587A
MA52587A MA052587A MA52587A MA52587A MA 52587 A MA52587 A MA 52587A MA 052587 A MA052587 A MA 052587A MA 52587 A MA52587 A MA 52587A MA 52587 A MA52587 A MA 52587A
Authority
MA
Morocco
Prior art keywords
pharmaceutical
azabenzimidazole compounds
azabenzimidazole
compounds
Prior art date
Application number
MA052587A
Other languages
English (en)
Other versions
MA52587B1 (fr
Inventor
Akiko FUJIBAYASHI
Sho Hirai
Kouya OIKAWA
Kazuhiko Wakita
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of MA52587A publication Critical patent/MA52587A/fr
Publication of MA52587B1 publication Critical patent/MA52587B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA52587A 2018-05-08 2019-05-07 Composés d'azabenzimidazole et produit pharmaceutique MA52587B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018089867 2018-05-08
EP19800286.7A EP3792260B1 (fr) 2018-05-08 2019-05-07 Composés d'azabenzimidazole et produit pharmaceutique
PCT/JP2019/018201 WO2019216294A1 (fr) 2018-05-08 2019-05-07 Composés d'azabenzimidazole et produit pharmaceutique

Publications (2)

Publication Number Publication Date
MA52587A true MA52587A (fr) 2021-03-17
MA52587B1 MA52587B1 (fr) 2024-10-31

Family

ID=68467433

Family Applications (1)

Application Number Title Priority Date Filing Date
MA52587A MA52587B1 (fr) 2018-05-08 2019-05-07 Composés d'azabenzimidazole et produit pharmaceutique

Country Status (35)

Country Link
US (1) US12319683B2 (fr)
EP (1) EP3792260B1 (fr)
JP (1) JP7235047B2 (fr)
KR (1) KR102819951B1 (fr)
CN (1) CN112368282B (fr)
AU (1) AU2019265134B2 (fr)
BR (1) BR112020022662A2 (fr)
CA (1) CA3099655A1 (fr)
CL (1) CL2020002868A1 (fr)
CO (1) CO2020013848A2 (fr)
DK (1) DK3792260T3 (fr)
EC (1) ECSP20078586A (fr)
ES (1) ES2992256T3 (fr)
FI (1) FI3792260T3 (fr)
HR (1) HRP20241414T1 (fr)
HU (1) HUE068695T2 (fr)
IL (1) IL278517B2 (fr)
LT (1) LT3792260T (fr)
MA (1) MA52587B1 (fr)
MD (1) MD3792260T2 (fr)
MX (1) MX2020011855A (fr)
MY (1) MY202833A (fr)
PE (1) PE20211384A1 (fr)
PH (1) PH12020551873A1 (fr)
PL (1) PL3792260T3 (fr)
PT (1) PT3792260T (fr)
RS (1) RS65996B1 (fr)
SA (1) SA520420487B1 (fr)
SG (1) SG11202011003TA (fr)
SI (1) SI3792260T1 (fr)
SM (1) SMT202400407T1 (fr)
TW (1) TWI868068B (fr)
UA (1) UA126774C2 (fr)
WO (1) WO2019216294A1 (fr)
ZA (1) ZA202007164B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3792260T3 (pl) 2018-05-08 2024-12-02 Nippon Shinyaku Co., Ltd. Związki azabenzimidazolowe i środki farmaceutyczne
WO2021095801A1 (fr) * 2019-11-13 2021-05-20 日本新薬株式会社 Composé azabenzimidazole et médicament
WO2021095805A1 (fr) * 2019-11-13 2021-05-20 日本新薬株式会社 Agent thérapeutique et agent prophylactique pour des troubles gastro-intestinaux fonctionnels et la xérostomie
CN118045050B (zh) * 2023-11-16 2025-06-10 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种头颈部放疗患者适用的缓解口腔干燥的组合物及其制备方法
WO2025153078A1 (fr) * 2024-01-17 2025-07-24 盛睿泽华医药科技（苏州）有限公司 Inhibiteur soluble d'époxyde hydrolase et son utilisation

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UA73543C2 (uk) 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
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PL3792260T3 (pl) 2018-05-08 2024-12-02 Nippon Shinyaku Co., Ltd. Związki azabenzimidazolowe i środki farmaceutyczne
TW202012415A (zh) 2018-05-08 2020-04-01 瑞典商阿斯特捷利康公司 化學化合物
WO2021095805A1 (fr) 2019-11-13 2021-05-20 日本新薬株式会社 Agent thérapeutique et agent prophylactique pour des troubles gastro-intestinaux fonctionnels et la xérostomie
WO2021095801A1 (fr) 2019-11-13 2021-05-20 日本新薬株式会社 Composé azabenzimidazole et médicament

Also Published As

Publication number Publication date
HUE068695T2 (hu) 2025-01-28
IL278517A (en) 2020-12-31
SI3792260T1 (sl) 2024-11-29
SG11202011003TA (en) 2020-12-30
US12319683B2 (en) 2025-06-03
JPWO2019216294A1 (ja) 2021-05-13
MX2020011855A (es) 2021-01-20
FI3792260T3 (fi) 2024-10-01
PL3792260T3 (pl) 2024-12-02
PE20211384A1 (es) 2021-07-27
CO2020013848A2 (es) 2021-01-29
RS65996B1 (sr) 2024-10-31
CA3099655A1 (fr) 2019-11-14
TW202016108A (zh) 2020-05-01
WO2019216294A1 (fr) 2019-11-14
KR102819951B1 (ko) 2025-06-13
IL278517B1 (en) 2024-05-01
ES2992256T3 (es) 2024-12-11
JP7235047B2 (ja) 2023-03-08
EP3792260A1 (fr) 2021-03-17
TWI868068B (zh) 2025-01-01
AU2019265134B2 (en) 2024-02-29
MA52587B1 (fr) 2024-10-31
IL278517B2 (en) 2024-09-01
LT3792260T (lt) 2024-10-25
HRP20241414T1 (hr) 2024-12-20
MD3792260T2 (ro) 2024-12-31
EP3792260A4 (fr) 2022-02-09
CL2020002868A1 (es) 2021-04-16
UA126774C2 (uk) 2023-02-01
CN112368282B (zh) 2023-10-13
AU2019265134A1 (en) 2020-12-17
KR20210006437A (ko) 2021-01-18
ECSP20078586A (es) 2021-01-29
ZA202007164B (en) 2024-06-26
PT3792260T (pt) 2024-10-02
US20210371412A1 (en) 2021-12-02
BR112020022662A2 (pt) 2021-02-09
SMT202400407T1 (it) 2024-11-15
SA520420487B1 (ar) 2024-03-17
MY202833A (en) 2024-05-24
CN112368282A (zh) 2021-02-12
PH12020551873A1 (en) 2021-05-31
DK3792260T3 (da) 2024-10-14
EP3792260B1 (fr) 2024-09-11

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