MA52772A - Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations - Google Patents

Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations

Info

Publication number
MA52772A
MA52772A MA052772A MA52772A MA52772A MA 52772 A MA52772 A MA 52772A MA 052772 A MA052772 A MA 052772A MA 52772 A MA52772 A MA 52772A MA 52772 A MA52772 A MA 52772A
Authority
MA
Morocco
Prior art keywords
monospecific
multispecific anti
tmeff2 antibodies
tmeff2
antibodies
Prior art date
Application number
MA052772A
Other languages
English (en)
Inventor
Phillip Cooper
Robin Ernst
Rajkumar Ganesan
Colleen Kane
Michael Russell
Sanjaya Singh
Sathyadevi Venkataramani
Sheng-Jiun Wu
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA52772A publication Critical patent/MA52772A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA052772A 2018-05-24 2019-05-21 Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations MA52772A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862675957P 2018-05-24 2018-05-24

Publications (1)

Publication Number Publication Date
MA52772A true MA52772A (fr) 2021-04-14

Family

ID=67211771

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052772A MA52772A (fr) 2018-05-24 2019-05-21 Anticorps anti-tmeff2 monospécifiques et multispécifiques et leurs utilisations

Country Status (24)

Country Link
US (1) US11866499B2 (fr)
EP (1) EP3802607A2 (fr)
JP (2) JP2021524255A (fr)
KR (1) KR20210011999A (fr)
CN (1) CN112703203B (fr)
AR (1) AR115419A1 (fr)
BR (1) BR112020023416A2 (fr)
CA (1) CA3101304A1 (fr)
CL (1) CL2020003032A1 (fr)
CO (1) CO2020014515A2 (fr)
CR (1) CR20200564A (fr)
EA (1) EA202092849A1 (fr)
EC (1) ECSP20075234A (fr)
IL (1) IL278862A (fr)
JO (1) JOP20200295A1 (fr)
MA (1) MA52772A (fr)
MX (1) MX2020012589A (fr)
NI (1) NI202000087A (fr)
PE (1) PE20210634A1 (fr)
PH (1) PH12020551948A1 (fr)
SG (1) SG11202011268VA (fr)
TW (1) TWI865451B (fr)
UY (1) UY38243A (fr)
WO (1) WO2019224713A2 (fr)

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MX420253B (es) * 2018-05-24 2025-02-10 Janssen Biotech Inc Anticuerpos anti-cd3 y usos de estos.
US20210214440A1 (en) * 2019-12-18 2021-07-15 Janssen Biotech, Inc. Materials and methods for in vivo biological targeting
IL298444A (en) 2020-05-27 2023-01-01 Janssen Biotech Inc Proteins containing cd3 antigen binding sites and uses thereof
CA3195114A1 (fr) * 2020-10-09 2022-04-14 Martin Klatt Compositions ciblant des complexes ndc80/mhc et utilisations associees
AR123767A1 (es) 2020-10-13 2023-01-11 Janssen Biotech Inc Inmunidad mediada por células t mediante bioingeniería, materiales y otros métodos para modular el cúmulo de diferenciación iv y/o viii
US12365743B2 (en) 2022-02-23 2025-07-22 Xencor, Inc. Anti-CD28 x anti-PSMA antibodies
JP2025530130A (ja) * 2022-09-09 2025-09-11 ヤンセン バイオテツク，インコーポレーテツド 抗ｔｍｅｆｆ２×ｃｄ３二重特異性抗体でがんを治療する方法

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Also Published As

Publication number Publication date
IL278862A (en) 2021-01-31
JP2021524255A (ja) 2021-09-13
CL2020003032A1 (es) 2021-04-16
US20190359711A1 (en) 2019-11-28
JP2024105476A (ja) 2024-08-06
TW202003584A (zh) 2020-01-16
TWI865451B (zh) 2024-12-11
AU2019274652A1 (en) 2020-11-26
CO2020014515A2 (es) 2020-12-10
JOP20200295A1 (ar) 2020-11-22
NI202000087A (es) 2021-03-23
ECSP20075234A (es) 2020-12-31
CA3101304A1 (fr) 2019-11-28
EA202092849A1 (ru) 2021-03-16
SG11202011268VA (en) 2020-12-30
BR112020023416A2 (pt) 2021-02-17
CR20200564A (es) 2021-06-21
WO2019224713A2 (fr) 2019-11-28
WO2019224713A3 (fr) 2020-01-02
MX2020012589A (es) 2021-01-29
EP3802607A2 (fr) 2021-04-14
AR115419A1 (es) 2021-01-13
PE20210634A1 (es) 2021-03-23
KR20210011999A (ko) 2021-02-02
UY38243A (es) 2019-11-29
CN112703203B (zh) 2025-02-25
US11866499B2 (en) 2024-01-09
CN112703203A (zh) 2021-04-23
PH12020551948A1 (en) 2021-08-16

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