MA53402A - Immunomodulateurs pour l'imagerie tep - Google Patents

Immunomodulateurs pour l'imagerie tep

Info

Publication number
MA53402A
MA53402A MA053402A MA53402A MA53402A MA 53402 A MA53402 A MA 53402A MA 053402 A MA053402 A MA 053402A MA 53402 A MA53402 A MA 53402A MA 53402 A MA53402 A MA 53402A
Authority
MA
Morocco
Prior art keywords
immunomodulators
pet imaging
pet
imaging
Prior art date
Application number
MA053402A
Other languages
English (en)
Inventor
Kenneth M Boy
David J Donnelly
Joonyoung Kim
Adrienne Pena
Yunhui Zhang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MA53402A publication Critical patent/MA53402A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12—Arrangements for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA053402A 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep MA53402A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662338872P 2016-05-19 2016-05-19

Publications (1)

Publication Number Publication Date
MA53402A true MA53402A (fr) 2021-06-02

Family

ID=59021563

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053402A MA53402A (fr) 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep

Country Status (25)

Country Link
US (2) US11103605B2 (fr)
EP (2) EP3458111B1 (fr)
JP (1) JP6953444B2 (fr)
KR (1) KR102378288B1 (fr)
CN (1) CN109414514B (fr)
AU (1) AU2017268291B2 (fr)
BR (1) BR112018073642A2 (fr)
CA (1) CA3024844A1 (fr)
CY (1) CY1124241T1 (fr)
DK (1) DK3458111T3 (fr)
EA (1) EA038019B1 (fr)
ES (1) ES2864091T3 (fr)
HR (1) HRP20210644T8 (fr)
HU (1) HUE054306T2 (fr)
IL (1) IL262962B (fr)
LT (1) LT3458111T (fr)
MA (1) MA53402A (fr)
MX (1) MX2018014028A (fr)
PL (1) PL3458111T3 (fr)
PT (1) PT3458111T (fr)
RS (1) RS61742B1 (fr)
SG (1) SG11201810177VA (fr)
SI (1) SI3458111T1 (fr)
SM (1) SMT202100238T1 (fr)
WO (1) WO2017201111A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9856292B2 (en) 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
WO2018048882A1 (fr) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Composition d'agent d'imagerie par tomographie par imagerie de positrons et méthode pour infection bactérienne
KR102611270B1 (ko) 2016-12-01 2023-12-08 리제너론 파마슈티칼스 인코포레이티드 면역-pet 영상화를 위한 방사성 표지된 항-pd-l1 항체
BR112019012986A2 (pt) * 2016-12-23 2019-12-03 Univ Johns Hopkins imageamento de tumores e de células imunes com base na expressão de pd-l1
JP7167041B2 (ja) 2017-02-10 2022-11-08 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 免疫ｐｅｔイメージングのための放射標識抗ｌａｇ３抗体
US11066445B2 (en) 2017-06-23 2021-07-20 Bristol-Myers Squibb Company Immunomodulators acting as antagonists of PD-1
BR112020001360A2 (pt) 2017-07-24 2020-08-11 Regeneron Pharmaceuticals, Inc. anticorpo monoclonal isolado ou fragmento de ligação a antígeno deste que se liga a cd8, composição farmacêutica, molécula de ácido nucleico, vetor de expressão, célula hospedeira, conjugado de anticorpo, métodos para gerar imagens de um tecido que expressa cd8, para tratar um sujeito tendo um tumor sólido, para prever uma resposta positiva a uma terapia antitumoral, para monitorar uma resposta de um tumor em um sujeito a uma terapia antitumoral, para prever ou monitorar a eficácia da terapia antitumoral e para monitorar a presença de células t em um tumor ao longo do tempo, e, composto.
EP3692053A1 (fr) 2017-10-03 2020-08-12 Bristol-Myers Squibb Company Immunomodulateurs
CN110504017B (zh) * 2019-07-30 2022-06-10 哈尔滨医科大学 一种示踪剂的制备和使用方法
US12403174B2 (en) 2020-01-06 2025-09-02 Bristol-Myers Squibb Company Immunomodulators
WO2021188480A1 (fr) * 2020-03-16 2021-09-23 Bristol-Myers Squibb Company Immunomodulateurs
US12421278B2 (en) 2020-03-30 2025-09-23 Bristol-Myers Squibb Company Immunomodulators
US12159403B2 (en) * 2021-06-18 2024-12-03 The United States Government As Represented By The Department Of Veteran Affairs Combination of features from biopsies and scans to predict prognosis in SCLC
KR20250117435A (ko) * 2022-12-12 2025-08-04 머크 샤프 앤드 돔 엘엘씨 그랜자임 b의 pet 영상화제로서의 시클릭 펩티드

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US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
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IL113610A0 (en) 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
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WO1997041898A1 (fr) 1996-05-03 1997-11-13 Immunomedics, Inc. Immunotherapie-cible associee contre le cancer
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US6277818B1 (en) 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
EP1009726B1 (fr) 1997-09-03 2007-02-14 Immunomedics, Inc. Fluoration de proteines et de peptides servant a une tomographie par emission de positrons f-18
EP2990411B1 (fr) 2007-03-26 2017-05-03 The University of Tokyo Procede pour synthetiser un compose peptidique cyclique
BRPI0917891A2 (pt) 2008-08-25 2015-11-24 Amplimmune Inc antagonistas de pd-1 e métodos de utilização dos mesmos
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JP6206943B2 (ja) 2010-12-03 2017-10-04 国立大学法人 東京大学 ペプチドライブラリーの製造方法、ペプチドライブラリー、及びスクリーニング方法
WO2013010573A1 (fr) * 2011-07-18 2013-01-24 Universitaet Muenster Composés avec activité inhibitrice de métalloprotéinase de matrice
EP2717895A1 (fr) 2011-06-08 2014-04-16 Aurigene Discovery Technologies Limited Composés thérapeutiques pour une immunomodulation
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JP2013253842A (ja) 2012-06-06 2013-12-19 Univ Of Tokyo ｐＨ依存的に標的分子に結合するペプチドのスクリーニング方法
ES2647076T3 (es) 2012-06-06 2017-12-19 Polyphor Ag Peptidomiméticos de horquilla beta
PL2972373T3 (pl) 2013-03-15 2020-03-31 F. Hoffmann-La Roche Ag Biomarkery i sposoby leczenia stanów związanych z PD-1 i PD-L1
US9308236B2 (en) 2013-03-15 2016-04-12 Bristol-Myers Squibb Company Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
HRP20181271T1 (hr) 2013-09-06 2018-10-05 Aurigene Discovery Technologies Limited Ciklički peptidomimetički spojevi kao imunomodulatori
WO2015044900A1 (fr) 2013-09-27 2015-04-02 Aurigene Discovery Technologies Limited Composés immunomodulateurs thérapeutiques
JP6405457B2 (ja) 2014-09-11 2018-10-17 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｐｄ−１／ｐｄ−ｌ１およびｃｄ８０（ｂ７−１）／ｐｄ−ｌ１タンパク質／タンパク質相互作用の大環状阻害剤
US9732119B2 (en) 2014-10-10 2017-08-15 Bristol-Myers Squibb Company Immunomodulators
US9856292B2 (en) * 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
EP4218832A3 (fr) 2014-11-25 2023-08-23 Bristol-Myers Squibb Company Méthodes et compositions pour radiomarquage au 18f du domaine de fibronectine iii
CN107406494B (zh) * 2014-11-25 2022-03-25 百时美施贵宝公司 用于成像的新型pd-l1结合多肽
US9861680B2 (en) 2014-12-18 2018-01-09 Bristol-Myers Squibb Company Immunomodulators
US9944678B2 (en) 2014-12-19 2018-04-17 Bristol-Myers Squibb Company Immunomodulators
US20160222060A1 (en) 2015-02-04 2016-08-04 Bristol-Myers Squibb Company Immunomodulators
US9809625B2 (en) 2015-03-18 2017-11-07 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
WO2017210335A1 (fr) 2016-06-01 2017-12-07 Bristol-Myers Squibb Company Méthodes d'imagerie faisant intervenir des substances biologiques radiomarquées au 18f
JP7085545B2 (ja) 2016-11-07 2022-06-16 ブリストル－マイヤーズ スクイブ カンパニー 免疫修飾因子
US11066445B2 (en) 2017-06-23 2021-07-20 Bristol-Myers Squibb Company Immunomodulators acting as antagonists of PD-1
EP3692053A1 (fr) 2017-10-03 2020-08-12 Bristol-Myers Squibb Company Immunomodulateurs

Also Published As

Publication number Publication date
JP6953444B2 (ja) 2021-10-27
US20210386876A1 (en) 2021-12-16
KR102378288B1 (ko) 2022-03-23
US11103605B2 (en) 2021-08-31
CN109414514B (zh) 2022-03-11
BR112018073642A2 (pt) 2019-02-26
IL262962B (en) 2020-04-30
PL3458111T3 (pl) 2021-06-28
ES2864091T3 (es) 2021-10-13
PT3458111T (pt) 2021-04-09
IL262962A (en) 2018-12-31
US20190117801A1 (en) 2019-04-25
WO2017201111A1 (fr) 2017-11-23
SI3458111T1 (sl) 2021-07-30
SG11201810177VA (en) 2018-12-28
CY1124241T1 (el) 2022-07-22
SMT202100238T1 (it) 2021-05-07
LT3458111T (lt) 2021-05-25
MX2018014028A (es) 2019-04-04
DK3458111T3 (da) 2021-04-26
EA201892635A1 (ru) 2019-04-30
CA3024844A1 (fr) 2017-11-23
AU2017268291A1 (en) 2019-01-17
KR20190009330A (ko) 2019-01-28
HRP20210644T1 (hr) 2021-05-28
EP3458111B1 (fr) 2021-03-03
EA038019B1 (ru) 2021-06-23
EP3458111A1 (fr) 2019-03-27
AU2017268291B2 (en) 2022-09-29
CN109414514A (zh) 2019-03-01
EP3827849A1 (fr) 2021-06-02
HRP20210644T8 (hr) 2021-06-25
JP2019520328A (ja) 2019-07-18
RS61742B1 (sr) 2021-05-31
HUE054306T2 (hu) 2021-08-30

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