MA53808A - Inhibiteurs de pde4 contenant du bore - Google Patents

Inhibiteurs de pde4 contenant du bore

Info

Publication number: MA53808A
Authority: MA; Morocco
Prior art keywords: boron; pde4 inhibitors; containing pde4; inhibitors; pde4
Prior art date: 2018-10-05

Application number

MA053808A

Other languages

English (en)

Inventor

Tsutomu Akama

David Clive Blakemore

Robert Toms Jacobs

Peter Jones

David Christopher Limburg

Martins Sunday Oderinde

Matthew Alexander Perry

Jacob John Plattner

Joseph Walter Strohbach

Rubben Federico Torella

Thean Yeow Yeoh

Yasheen Zhou

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-10-05

Filing date

2019-10-01

Publication date

2022-01-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=68136492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA53808(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2019-10-01 Application filed by Pfizer filed Critical Pfizer

2022-01-12 Publication of MA53808A publication Critical patent/MA53808A/fr

Links

229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title 1
239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

MA053808A 2018-10-05 2019-10-01 Inhibiteurs de pde4 contenant du bore MA53808A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201862741868P	2018-10-05	2018-10-05
US201962889599P	2019-08-21	2019-08-21

Publications (1)

Publication Number	Publication Date
MA53808A true MA53808A (fr)	2022-01-12

Family

ID=68136492

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA053808A MA53808A (fr)	2018-10-05	2019-10-01	Inhibiteurs de pde4 contenant du bore

Country Status (30)

Country	Link
US (3)	US10946031B2 (fr)
EP (1)	EP3861001B1 (fr)
JP (1)	JP7048823B2 (fr)
KR (1)	KR102576125B1 (fr)
CN (1)	CN113166177B (fr)
AU (1)	AU2019351960B2 (fr)
BR (1)	BR112021005870B1 (fr)
CA (1)	CA3114702C (fr)
CL (1)	CL2021000843A1 (fr)
CO (1)	CO2021003928A2 (fr)
CR (1)	CR20210163A (fr)
CU (1)	CU20210023A7 (fr)
DK (1)	DK3861001T3 (fr)
DO (1)	DOP2021000055A (fr)
EC (1)	ECSP21023404A (fr)
ES (1)	ES2974208T3 (fr)
FI (1)	FI3861001T3 (fr)
GE (2)	GEAP202215599A (fr)
IL (1)	IL282083B2 (fr)
MA (1)	MA53808A (fr)
MX (1)	MX2021003871A (fr)
NI (1)	NI202100020A (fr)
PE (1)	PE20211546A1 (fr)
PH (1)	PH12021550743A1 (fr)
PY (1)	PY1983118A (fr)
SG (1)	SG11202102674RA (fr)
TW (1)	TWI764052B (fr)
UY (1)	UY38400A (fr)
WO (1)	WO2020070651A1 (fr)
ZA (1)	ZA202101822B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2021000795A (es)	2018-07-24	2021-04-12	Taiho Pharmaceutical Co Ltd	Compuestos heterociclicos para inhibir la actividad de shp2.
GB201911928D0 (en)	2019-08-20	2019-10-02	Otsuka Pharma Co Ltd	Pharmaceutical compounds
JP2023538362A (ja) *	2020-08-20	2023-09-07	ファイザー・インク	１（ｒ）－４－（５－（４－メトキシ－３－プロポキシフェニル）ピリジン－３－イル）－１，２－オキサボロラン－２－オールの安定な局所製剤
EP4204012A1 (fr)	2020-08-31	2023-07-05	Pfizer Inc.	Procédés de protection de l'arn
JP7838832B2 (ja) *	2020-12-25	2026-04-01	瑞石生物医薬有限公司	ボレート誘導体及びその使用
CN119403811A (zh) *	2022-06-24	2025-02-07	瑞石生物医药有限公司	一种硼酸酯衍生物的可药用盐、其结晶形式及用途
TW202404610A (zh)	2022-06-24	2024-02-01	大陸商瑞石生物醫藥有限公司	一種硼酸酯衍生物的結晶、其製備方法及用途
GB202306663D0 (en)	2023-05-05	2023-06-21	Union Therapeutics As	Combination therapy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9411587D0 (en)	1994-06-09	1994-08-03	Zeneca Ltd	Compound, composition and use
ES2287971T3 (es)	1997-08-11	2007-12-16	Pfizer Products Inc.	Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
EP2343304B1 (fr) *	2005-02-16	2015-06-10	Anacor Pharmaceuticals, Inc.	Composés boronophthalide biocides
JO3598B1 (ar) *	2006-10-10	2020-07-05	Infinity Discovery Inc	الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
WO2009111676A2 (fr)	2008-03-06	2009-09-11	Anacor Pharmaceuticals, Inc	Petites molécules contenant du bore utilisées en tant qu'agents anti-inflammatoires
JP5745279B2 (ja) *	2008-01-09	2015-07-08	アナコールファーマシューティカルズ，インコーポレイテッド	抗炎症剤としてのホウ素含有小分子
KR20150065941A (ko) *	2008-03-06	2015-06-15	아나코르 파마슈티칼스 인코포레이티드	소염제로써 붕소가 함유된 소분자
AU2011329485A1 (en) *	2010-11-18	2013-04-18	Glaxo Group Limited	Compounds
CN108142434A (zh)	2011-10-07	2018-06-12	先正达参股股份有限公司	用于保护有用植物或植物繁殖材料的方法
HRP20230162T1 (hr) *	2012-10-25	2023-04-14	Tetra Discovery Partners Llc	Heteroarilni inhibitori enzima pde4
EP2752196A1 (fr) *	2013-01-03	2014-07-09	Université Bordeaux Segalen	Peptides inhibiteurs nox-1 sélectifs et leurs utilisations
MA38319A1 (fr)	2013-01-30	2016-08-31	Dow Agrosciences Llc	Utilisation des benzoxaboroles à titre d'agents antimicrobiens volatils sur les viandes, les plantes, ou des parties de plantes
WO2014147009A1 (fr) *	2013-03-18	2014-09-25	Syngenta Participations Ag	Nouveaux microbiocides
AU2014202928B1 (en)	2013-06-05	2014-09-11	Agrofresh Inc.	Compounds and compositions
GB201705263D0 (en) *	2017-03-31	2017-05-17	Probiodrug Ag	Novel inhibitors
US11919902B2 (en) *	2017-12-22	2024-03-05	Hibercell, Inc.	Aryl-bipyridine amine derivatives as phosphatidylinositol phosphate kinase inhibitors

2019
- 2019-10-01 CR CR20210163A patent/CR20210163A/es unknown
- 2019-10-01 MX MX2021003871A patent/MX2021003871A/es unknown
- 2019-10-01 EP EP19782756.1A patent/EP3861001B1/fr active Active
- 2019-10-01 GE GEAP202215599A patent/GEAP202215599A/en unknown
- 2019-10-01 FI FIEP19782756.1T patent/FI3861001T3/fi active
- 2019-10-01 KR KR1020217013141A patent/KR102576125B1/ko active Active
- 2019-10-01 BR BR112021005870-2A patent/BR112021005870B1/pt active IP Right Grant
- 2019-10-01 AU AU2019351960A patent/AU2019351960B2/en not_active Ceased
- 2019-10-01 CU CU2021000023A patent/CU20210023A7/es unknown
- 2019-10-01 ES ES19782756T patent/ES2974208T3/es active Active
- 2019-10-01 SG SG11202102674RA patent/SG11202102674RA/en unknown
- 2019-10-01 MA MA053808A patent/MA53808A/fr unknown
- 2019-10-01 CA CA3114702A patent/CA3114702C/fr active Active
- 2019-10-01 JP JP2021518191A patent/JP7048823B2/ja active Active
- 2019-10-01 GE GEAP201915599A patent/GEP20227442B/en unknown
- 2019-10-01 WO PCT/IB2019/058355 patent/WO2020070651A1/fr not_active Ceased
- 2019-10-01 CN CN201980080149.6A patent/CN113166177B/zh active Active
- 2019-10-01 PE PE2021000415A patent/PE20211546A1/es unknown
- 2019-10-01 DK DK19782756.1T patent/DK3861001T3/da active
- 2019-10-01 IL IL282083A patent/IL282083B2/en unknown
- 2019-10-03 UY UY0001038400A patent/UY38400A/es not_active Application Discontinuation
- 2019-10-04 US US16/593,171 patent/US10946031B2/en active Active
- 2019-10-04 TW TW108135972A patent/TWI764052B/zh active
- 2019-10-04 PY PY201901983118A patent/PY1983118A/es unknown
2020
- 2020-10-28 US US17/082,102 patent/US11559538B2/en active Active
2021
- 2021-03-18 ZA ZA2021/01822A patent/ZA202101822B/en unknown
- 2021-03-18 NI NI202100020A patent/NI202100020A/es unknown
- 2021-03-29 CO CONC2021/0003928A patent/CO2021003928A2/es unknown
- 2021-03-31 DO DO2021000055A patent/DOP2021000055A/es unknown
- 2021-04-05 CL CL2021000843A patent/CL2021000843A1/es unknown
- 2021-04-05 PH PH12021550743A patent/PH12021550743A1/en unknown
- 2021-04-05 EC ECSENADI202123404A patent/ECSP21023404A/es unknown
2022
- 2022-12-15 US US18/066,468 patent/US20230148402A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PH12021550743A1 (en)	2021-10-11
CN113166177A (zh)	2021-07-23
US20230148402A1 (en)	2023-05-11
TWI764052B (zh)	2022-05-11
US20210069219A1 (en)	2021-03-11
CN113166177B (zh)	2024-09-03
ZA202101822B (en)	2022-08-31
CA3114702A1 (fr)	2020-04-09
JP2021534222A (ja)	2021-12-09
CU20210023A7 (es)	2021-10-12
EP3861001B1 (fr)	2023-12-13
IL282083A (en)	2021-05-31
ECSP21023404A (es)	2021-05-31
ES2974208T3 (es)	2024-06-26
US10946031B2 (en)	2021-03-16
AU2019351960B2 (en)	2022-07-28
TW202027755A (zh)	2020-08-01
SG11202102674RA (en)	2021-04-29
GEP20227442B (en)	2022-11-25
AU2019351960A1 (en)	2021-04-29
PE20211546A1 (es)	2021-08-16
FI3861001T3 (fi)	2024-01-03
DK3861001T3 (da)	2024-01-15
PY1983118A (es)	2021-07-15
CR20210163A (es)	2021-06-24
BR112021005870A2 (pt)	2021-07-27
IL282083B1 (en)	2025-01-01
MX2021003871A (es)	2021-05-27
EP3861001A1 (fr)	2021-08-11
KR102576125B1 (ko)	2023-09-08
JP7048823B2 (ja)	2022-04-05
IL282083B2 (en)	2025-05-01
DOP2021000055A (es)	2021-05-16
KR20210068532A (ko)	2021-06-09
BR112021005870B1 (pt)	2024-01-09
CA3114702C (fr)	2023-08-08
NI202100020A (es)	2021-08-24
US11559538B2 (en)	2023-01-24
UY38400A (es)	2020-04-30
CL2021000843A1 (es)	2021-09-10
GEAP202215599A (en)	2022-08-10
WO2020070651A1 (fr)	2020-04-09
CO2021003928A2 (es)	2021-04-19
US20200108083A1 (en)	2020-04-09

Publication	Publication Date	Title
IL283639A (en)	2021-07-29	Kif18a inhibitors
MA53808A (fr)	2022-01-12	Inhibiteurs de pde4 contenant du bore
MA54550A (fr)	2022-03-30	Inhibiteurs de kif18a
EP4007752C0 (fr)	2025-09-24	Inhibiteurs de kif18a
EP3898616C0 (fr)	2024-10-02	Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a
EP3898592C0 (fr)	2024-10-09	Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a
EP4007753C0 (fr)	2025-09-24	Inhibiteurs de kif18a
DK3740479T3 (da)	2025-01-13	Dna-pk-hæmmere
EP3801503A4 (fr)	2021-12-08	Inhibiteurs de sarm1
LT3661921T (lt)	2024-02-12	Selektyvūs nlrp3 inflamasomos inhibitoriai
EP3541932A4 (fr)	2021-03-03	Inhibiteurs de crispr-cas9
PT3565520T (pt)	2026-03-12	Composições anidras de inibidores de mtor e métodos de utilização
EP3761992A4 (fr)	2021-11-24	Inhibiteurs d'arginase
MA52813A (fr)	2021-04-14	Inhibiteurs de sarm1
EP3347008A4 (fr)	2019-04-10	Inhibiteurs de bêta-lactamases
DK3571192T3 (da)	2023-02-06	Jak1-selektive inhibitorer
DK3681884T3 (da)	2022-08-22	Rad51-inhibitorer
EP3817736A4 (fr)	2021-07-28	Inhibiteurs de pikfyve
EP3980011C0 (fr)	2025-12-17	Inhibiteurs de sarm1
MA52809A (fr)	2021-04-14	Inhibiteurs de sarm1
EP3609882A4 (fr)	2020-10-28	Inhibiteurs hétérocycliques de pcsk9
DK3668955T3 (da)	2023-02-27	Korrosionsinhibitor
DK3630744T3 (da)	2023-03-06	Pyrazol-magl-inhibitorer
IL281514A (en)	2021-04-29	O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors
EP3502111A4 (fr)	2020-05-20	Inhibiteur de pde4