MA53859A - Procédé de transfert de gaz de membrane dans une culture de bioréacteur à haute densité - Google Patents

Procédé de transfert de gaz de membrane dans une culture de bioréacteur à haute densité

Info

Publication number
MA53859A
MA53859A MA053859A MA53859A MA53859A MA 53859 A MA53859 A MA 53859A MA 053859 A MA053859 A MA 053859A MA 53859 A MA53859 A MA 53859A MA 53859 A MA53859 A MA 53859A
Authority
MA
Morocco
Prior art keywords
gas transfer
membrane gas
bioreactor culture
density bioreactor
density
Prior art date
Application number
MA053859A
Other languages
English (en)
Inventor
jonathan Coffman
Scott Godfrey
Lisa Sawicki
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MA53859A publication Critical patent/MA53859A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26—Conditioning fluids entering or exiting the reaction vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/02—Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
MA053859A 2018-10-10 2019-10-08 Procédé de transfert de gaz de membrane dans une culture de bioréacteur à haute densité MA53859A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862743767P 2018-10-10 2018-10-10

Publications (1)

Publication Number Publication Date
MA53859A true MA53859A (fr) 2022-01-19

Family

ID=68345046

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053859A MA53859A (fr) 2018-10-10 2019-10-08 Procédé de transfert de gaz de membrane dans une culture de bioréacteur à haute densité

Country Status (6)

Country Link
US (2) US12415980B2 (fr)
EP (1) EP3864127A1 (fr)
KR (1) KR20210074341A (fr)
CN (1) CN113166695A (fr)
MA (1) MA53859A (fr)
WO (1) WO2020076776A1 (fr)

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JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
KR20210074341A (ko) 2018-10-10 2021-06-21 베링거 인겔하임 인터내셔날 게엠베하 고밀도 생물 반응기 배양에서 막 기체 전달을 위한 방법
CN111454841A (zh) * 2020-05-26 2020-07-28 上海艾众生物科技有限公司 用于生物反应器的通气装置
CN111484937A (zh) * 2020-05-26 2020-08-04 上海艾众生物科技有限公司 用于生物反应器的培养基外循环更新装置
EP4176041A1 (fr) * 2020-07-06 2023-05-10 Merck Patent GmbH Dispositif et procédé pour la préparation de milieux de culture cellulaire et la réalisation d'une culture cellulaire
CN112210504B (zh) * 2020-10-15 2021-05-18 新疆天润生物科技股份有限公司 一种马克思克鲁维酵母菌菌株的培养方法
CN113388515A (zh) * 2021-05-21 2021-09-14 瑞太生物科技(沈阳)有限公司 一种用于外泌体生产制备的系统及其制备外泌体的方法
JP7299437B1 (ja) 2022-08-08 2023-06-27 日機装株式会社 培養システム
EP4324905A1 (fr) * 2022-08-19 2024-02-21 Sartorius Stedim Biotech GmbH Système de bioréacteur avec installation de fumigation
CN120569467A (zh) * 2022-10-31 2025-08-29 Abec公司 旋转混合式细胞培养生物反应器
EP4647486A3 (fr) * 2022-11-15 2026-01-14 Asahi Kasei Life Science Corporation Procédé de production de produit cellulaire, procédé de purification de produit cellulaire, procédé de suppression de la diminution de perméabilité membranaire
CN116041103B (zh) * 2023-02-01 2025-04-11 郑州大学 一种易于微生物发酵的有机肥料生产加工设备
WO2024218715A1 (fr) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Milieu de culture à base d'hydrolysat de protéines et leur procédé de préparation
US20240360399A1 (en) * 2023-04-26 2024-10-31 Terumo Bct, Inc. Methods To Remove Solutes Without Suspension Cell Loss
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation
CN119001024A (zh) * 2024-08-22 2024-11-22 楚天科技股份有限公司 一种生物反应器中传质系数的测定方法
WO2026119859A1 (fr) * 2024-12-05 2026-06-11 Wageningen Universiteit Insert destiné à être inséré dans un milieu de croissance, et procédé associé
CN120555192A (zh) * 2025-08-01 2025-08-29 苏州英赛斯智能科技有限公司 生物反应装置及生物培养方法

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Also Published As

Publication number Publication date
US12415980B2 (en) 2025-09-16
CN113166695A (zh) 2021-07-23
US20210380923A1 (en) 2021-12-09
EP3864127A1 (fr) 2021-08-18
KR20210074341A (ko) 2021-06-21
WO2020076776A1 (fr) 2020-04-16
US20250368939A1 (en) 2025-12-04

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